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1.
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation.
Proc Natl Acad Sci U S A
; 106(37): 15950-5, 2009 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19717450
2.
The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.
J Neurosci
; 23(20): 7586-91, 2003 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-12930797
3.
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo.
J Med Chem
; 47(24): 5825-8, 2004 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-15537338
4.
A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors.
Eur J Pharmacol
; 450(1): 19-28, 2002 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12176104
5.
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
J Pharmacol Exp Ther
; 313(1): 199-206, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15608073
6.
Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents.
J Pharmacol Exp Ther
; 306(1): 116-23, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12660307
7.
Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides.
ChemMedChem
; 1(8): 807-11, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16902933
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