Emergence of high level azithromycin-resistant Neisseria gonorrhoeae strain isolated in Argentina.

One Neisseria gonorrhoeae strains highly resistant to azithromycin AzHLR (MIC >2048 mg/L) was isolated in Argentina in 2001 and it has been characterized by N. gonorrhoeae multiantigen sequence typing (NG-MAST) as ST696, suggesting a different event to other isolates in Europe. Neither, mtrR mutations or presence of mef gene were detected.

El Linfogranuloma venéreo rectal: presentación clínica emergente / Rectal lymphogranuloma venereum: an emergent clinical presentation

El linfogranuloma venéreo (LGV) es una enfermedad de transmisión sexual (ETS) poco frecuente causada por los serotipos L1, L2 y L3 de Chlamydia trachomatis.Desde hace más de una década se produjo un aumento de la incidencia de proctitis por LGV casi exclusivamente en hombres que tienen sexo con hombres con prácticas sexuales de riesgo para ETS.Se presentan cuatro casos con LGV rectal

Lymphogranuloma venereum is a rare sexually transmitted infection (STI) caused by serotypes L1, L2 and L3 of Chlamydia trachomatis.For over a decade, there has been a considerable increase in the incidence of LGV proctitis in almost exclusively men who have sex with men with STI risk behaviors.Four cases of rectal LGV are reported

[Study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis, in patients of the Francisco J. Muñiz Infectious Diseases Hospital]. / Estudio de las vulvovaginitis agudas en pacientes adultas, sexualmente activas, con especial referencia a la candidiasis, en pacientes del hospital de infecciosas Francisco J. Muñiz.

The results of microbiological vaginal secretions samples obtained from 749 women (from July 2001 to July 2002) were studied in the Bacteriology Unit of the Francisco Javier Muñiz Hospital from Buenos Aires. All patients suffered acute vulvovaginitis were child bearing and sexually active women, 334 of them were HIV-positive. The following are the results of the microbiological studies: Lactobacillus spp 50.6%, Gardnerella vaginalis 25.6%, Candida spp 17.4%, Trichomonas vaginalis 5.3%, Neisseria gonorrhoeae 0.3% and B group Streptococcus 0.8%. Candida vaginitis was significantly more frequent in HIV-positive patients, (21.6% vs 14%; p = 0.0086); meanwhile, trichomoniasis was less common although the difference was not statistically significant (3.6 vs 6.7%, p = 0.0810). The following Candida species were isolated in this study: Candida albicans 76.8%, Candida glabrata 15.6%, Candida parapsilosis 2.9%, Candida tropicalis 1.5% and Candida krusei 0.7%. Eight cases (6.2%) of vaginitis were produced by two Candida species (C. albicans and C. glabrata), and in three cases (2.17%) Saccharomyces cerevisiae were isolated. Five women suffering acute vaginitis with Candida spp presented another etiologic agent of vaginal infection, three cases T. vaginalis and two cases G. vaginalis. The following are some of the most important findings of this study: 1) Half of the patients presented a normal microbial biota; 2) Candida spp vaginitis was significantly more frequent among HIV-positive women; 3) we observed a high incidence of Candida glabrata infections (15.9%), 4) 6.2% of vaginal candidiasis were caused by more than one Candida species and, 5) the susceptibility pattern of C. albicans and C. glabrata isolates against fluconazole was similar to the one observed in other studies. The majority of C. albicans isolates were susceptible to fluconazole (MIC90 = 0.5 microg/ml) meanwhile C. glabrata strains were much less susceptible to this drug (MIC50 and MIC90 = 32 microg/ml).

Incremento de cepas de neisseria gonorrhoeae productoras de beta lactamasa en nuestro medio / An increase of beta lactamase producing Neisseria gonorrhoeae in our environment

El objetivo de este trabajo fue determinar el porcentaje de cepas de Neisseria gonorrhoeae productoras de beta lactamasa (PPNG) , su distribución en nuestro medio y su correlación en pacientes tratados previamente con antibióticos beta lactámicos. Hemos notado un gran incremento de cepas PPNG en el último trienio. Dicho incremento tal vez esté relacionado en gran medida a tratamientos inadecuados con antibióticos beta lactámicos no respaldados por un estudio bacteriológico previo con tipificación del germen y determinación de beta lactamas. Se señala por lo tanto la importancia de realizar dicho estudio para asegurar una terapéutica adecuada

Importancia del método iodométrico en medio sólido en la detección de Beta Lactamas en Neisseria gonorrhoeae / Importance of the iodometric solid medium method for beta lactamasa detection in Neisseria gonorrhoeae

Se realizó la determinación de Beta Lactamas (B.L. sobre 137 cepas de Neisseria gonorrhoeae por los métodos de la Cefalosporina Cromogénica (C.C.) (Nitrocefin) y método lodométrico en medio sólido (I.M.S>). Notamos una concidencia del 100% entre ambos métodos tanto en resultados positivos (detección de B.L.) como en resultados negativos (no detección de B.L.) y una mayor rapidez con la técnica de la C.C. (promèdio 5 minutos) en comparación con el I.M.S. (promedio 2 horas). Debido a la difícil provisión en nuestro medio de la C.C. y su elevado valor comercial, la técnica I.M.S. descripta adquiere mayor importancia por ser confiable, sencilla y de bajo costo