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1.
Opt Express ; 26(4): 4004-4022, 2018 Feb 19.
Artículo en Inglés | MEDLINE | ID: mdl-29475257

RESUMEN

Free space optical communications utilizing orbital angular momentum beams have recently emerged as a new technique for communications with potential for increased channel capacity. Turbulence due to changes in the index of refraction emanating from temperature, humidity, and air flow patterns, however, add nonlinear effects to the received patterns, thus making the demultiplexing task more difficult. Deep learning techniques have been previously been applied to solve the demultiplexing problem as an image classification task. Here we make use of a newly developed theory suggesting a link between image turbulence and photon transport through the continuity equation to describe a method that utilizes a "shallow" learning method instead. The decoding technique is tested and compared against previous approaches using deep convolutional neural networks. Results show that the new method can obtain similar classification accuracies (bit error ratio) at a small fraction (1/90) of the computational cost, thus enabling higher bit rates.

2.
Neuroimage Clin ; 12: 990-1003, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27995065

RESUMEN

Brain amyloid burden may be quantitatively assessed from positron emission tomography imaging using standardised uptake value ratios. Using these ratios as an adjunct to visual image assessment has been shown to improve inter-reader reliability, however, the amyloid positivity threshold is dependent on the tracer and specific image regions used to calculate the uptake ratio. To address this problem, we propose a machine learning approach to amyloid status classification, which is independent of tracer and does not require a specific set of regions of interest. Our method extracts feature vectors from amyloid images, which are based on histograms of oriented three-dimensional gradients. We optimised our method on 133 18F-florbetapir brain volumes, and applied it to a separate test set of 131 volumes. Using the same parameter settings, we then applied our method to 209 11C-PiB images and 128 18F-florbetaben images. We compared our method to classification results achieved using two other methods: standardised uptake value ratios and a machine learning method based on voxel intensities. Our method resulted in the largest mean distances between the subjects and the classification boundary, suggesting that it is less likely to make low-confidence classification decisions. Moreover, our method obtained the highest classification accuracy for all three tracers, and consistently achieved above 96% accuracy.


Asunto(s)
Enfermedad de Alzheimer/diagnóstico por imagen , Enfermedad de Alzheimer/metabolismo , Amiloide/metabolismo , Encéfalo/metabolismo , Interpretación de Imagen Asistida por Computador/métodos , Tomografía de Emisión de Positrones/métodos , Máquina de Vectores de Soporte , Anciano , Anciano de 80 o más Años , Enfermedad de Alzheimer/clasificación , Compuestos de Anilina , Encéfalo/diagnóstico por imagen , Radioisótopos de Carbono , Glicoles de Etileno , Femenino , Humanos , Masculino , Radiofármacos , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Estilbenos
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