Detalles de la búsqueda
1.
Amine-Linked Flavonoids as Agents Against Cutaneous Leishmaniasis.
Antimicrob Agents Chemother
; 65(5)2023 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33685890
2.
In Vivo Reversal of P-Glycoprotein-Mediated Drug Resistance in a Breast Cancer Xenograft and in Leukemia Models Using a Novel, Potent, and Nontoxic Epicatechin EC31.
Int J Mol Sci
; 24(5)2023 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36901808
3.
Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel.
Int J Mol Sci
; 23(23)2022 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36499627
4.
Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)2, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP/ABCG2).
Int J Mol Sci
; 23(21)2022 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-36362047
5.
Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer.
BMC Cancer
; 20(1): 964, 2020 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33023525
6.
Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1,2-benzisothiazol-3(2H)-one derivatives as potent New Delhi metallo-ß-lactamase inhibitors.
Bioorg Chem
; 100: 103873, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32361294
7.
Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.
J Cell Biochem
; 117(10): 2357-69, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26950525
8.
A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo.
Mol Pharm
; 12(10): 3507-17, 2015 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26291333
9.
In vitro and in vivo efficacy of novel flavonoid dimers against cutaneous leishmaniasis.
Antimicrob Agents Chemother
; 58(6): 3379-88, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24687505
10.
Determination of exogenous epigallocatechin gallate peracetate in mouse plasma using liquid chromatography with quadrupole time-of-flight mass spectrometry.
J Sep Sci
; 37(23): 3473-80, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25250898
11.
Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis.
J Pharm Anal
; 14(1): 100-114, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38352946
12.
Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice.
Angiogenesis
; 16(1): 59-69, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22948799
13.
Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening.
J Chem Inf Model
; 53(8): 2131-40, 2013 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23848971
14.
Identification of Binding Sites in the Nucleotide-Binding Domain of P-Glycoprotein for a Potent and Nontoxic Modulator, the Amine-Containing Monomeric Flavonoid FM04.
J Med Chem
; 66(9): 6160-6183, 2023 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37098275
15.
Validation of the AmpC ß-lactamase binding site and identification of inhibitors with novel scaffolds.
J Chem Inf Model
; 52(5): 1367-75, 2012 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22559726
16.
Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.
Bioorg Med Chem
; 20(9): 3031-7, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22459208
17.
Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled to quadrupole-time-of-flight-mass-spectrometry.
Front Pharmacol
; 13: 1025053, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36304154
18.
A novel liquid-phase strategy for organic synthesis using organic ions as soluble supports.
Chem Soc Rev
; 39(8): 2977-3006, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20480066
19.
An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis.
Front Pharmacol
; 12: 714790, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34721014
20.
Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2).
J Med Chem
; 64(19): 14311-14331, 2021 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34606270