Add-on Eye Movement Desensitization and Reprocessing (EMDR) Therapy for Adults with Post-traumatic Stress Disorder Who Failed to Respond to Initial Antidepressant Pharmacotherapy.

This study examined the add-on efficacy of eye movement desensitization and reprocessing (EMDR) therapy among adult civilians with post-traumatic stress disorder (PTSD) who continued to be symptomatic after more than 12 weeks of initial antidepressant treatment. Scores for the Clinician Administered PTSD Scale (CAPS) were rated pre- and post-EMDR and at a 6-month follow-up. After an average of six sessions of EMDR treatment, seven of 14 patients (50%) showed more than a 30% decrease in CAPS score and eight (57%) no longer met the criteria for PTSD. Our results indicate that EMDR could be successfully added after failure of initial pharmacotherapy for PTSD.

Deep-Learning-Based Recovery of Missing Optical Marker Trajectories in 3D Motion Capture Systems.

Motion capture (MoCap) technology, essential for biomechanics and motion analysis, faces challenges from data loss due to occlusions and technical issues. Traditional recovery methods, based on inter-marker relationships or independent marker treatment, have limitations. This study introduces a novel U-net-inspired bi-directional long short-term memory (U-Bi-LSTM) autoencoder-based technique for recovering missing MoCap data across multi-camera setups. Leveraging multi-camera and triangulated 3D data, this method employs a sophisticated U-shaped deep learning structure with an adaptive Huber regression layer, enhancing outlier robustness and minimizing reconstruction errors, proving particularly beneficial for long-term data loss scenarios. Our approach surpasses traditional piecewise cubic spline and state-of-the-art sparse low rank methods, demonstrating statistically significant improvements in reconstruction error across various gap lengths and numbers. This research not only advances the technical capabilities of MoCap systems but also enriches the analytical tools available for biomechanical research, offering new possibilities for enhancing athletic performance, optimizing rehabilitation protocols, and developing personalized treatment plans based on precise biomechanical data.

Prevalence and clinical correlates of dissociative subtype of posttraumatic stress disorder at an outpatient trauma clinic in South Korea.

Background: Previous studies on of the dissociative subtype of posttraumatic stress disorder (d-PTSD) have relied on specialized statistical methods (i.e. profile or class analyses) for diagnosis than clinical rating available to clinicians. Objective: This study investigated the prevalence and covariates of d-PTSD diagnosed by a semi-structured interview in a cohort of outpatients with DSM-IV PTSD in a specialized trauma clinic in South Korea. Method: Data from 249 patients with civilian PTSD were examined, including demographics, clinical variables, Clinical Global Impression (CGI) Scale, and Clinician-Administered PTSD Scale (CAPS-IV). We defined d-PTSD as the presence of either depersonalization or derealization according to additional dissociative items of the CAPS. About one third (n = 82, 32.9%) of patients were designated as having d-PTSD. Results: Compared to the other patients with PTSD, those with d-PTSD were younger, had more severe PTSD symptoms, frequent interpersonal trauma, and a higher number of comorbid disorders. When these variables and their interactions were entered into a logistic regression model, younger age, severe PTSD symptoms and two or more comorbid conditions remained for the final model. We did not find a significant difference in improvement over the course of treatment between two groups. Conclusions: This study highlights the high prevalence of d-PTSD in a clinical population. Associated features of d-PTSD were similar to those reported in the Euro-American literature. Further studies are needed to better understand mechanisms and treatment options for d-PTSD.

Antecedentes: los estudios previos del trastorno de estrés postraumático, subtipo disociativo (TEPT-d) se han basado en métodos estadísticos especializados (es decir, análisis de perfil o clase) para el diagnóstico en vez de la calificación clínica disponible para los médicos.Objetivo: Este estudio investigó la prevalencia y las covariables de TEPT-d diagnosticadas por una entrevista semiestructurada en una cohorte de pacientes ambulatorios con diagnóstico TEPT, según DSM IV, en una clínica especializada en trauma en Corea del Sur.Método: Se examinaron datos de 249 pacientes con TEPT civil, incluidos datos demográficos, variables clínicas, Escala de Impresión Clínica Global (CGI) y Escala de TEPT administrada por el médico (CAPS-IV). Definimos TEPT-d como la presencia de despersonalización o desrealización de acuerdo con ítems disociativos adicionales de la CAPS. Alrededor de un tercio (n = 82, 32.9%) de los pacientes fueron designados como TEPT-dResultados: en comparación con los otros pacientes con TEPT, los que tenían TEPT-d eran más jóvenes, tenían síntomas de TEPT más graves, mayor frecuencia de traumas interpersonales y un mayor número de trastornos comórbidos. Cuando estas variables y sus interacciones se ingresaron en un modelo de regresión logística, la edad más joven, los síntomas graves de TEPT y dos o más condiciones comórbidas permanecieron para el modelo final. No encontramos diferencias significativas en la mejora en el curso del tratamiento entre los dos grupos.Conclusiones: este estudio destaca la alta prevalencia de TEPT-d en una población clínica. Las características asociadas a TEPT-d fueron similares a las reportadas en la literatura Euroamericana. Se necesitan más estudios para comprender mejor los mecanismos y las opciones de tratamiento para TEPT-d.