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1.
Clin Anat ; 35(6): 698-700, 2022 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-35333413

RESUMEN

The newest influx of young learners of anatomy in medical education belong to Generation Z (GenZ), a unique generation of individuals that are vastly different from the Millennial and GenZ trainees before them. It has been shown that the first wave of GenZ members entering the workforce possess considerable talent for innovation and dedication to their work. However, recent evidence suggests that GenZ learners are also potently susceptible to environmental influences and place heavy emphasis on personal relationships developed with their instructors. This characteristic presents a challenge to current instructors of clinical anatomy participating in intergenerational teaching, especially with respect to instructing the intangible aspects of a successful academic career. This article highlights the pressing educational challenges faced by anatomy instructors and provides a concise method to reach GenZ trainees in a way that will help prepare them for the personal and professional milestones needed to achieve a successful academic and clinical career.


Asunto(s)
Anatomistas , Anatomía , Educación Médica , Anatomía/educación , Humanos , Enseñanza
2.
Neurosurg Rev ; 44(2): 763-772, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32318923

RESUMEN

The pharyngeal plexus is an essential anatomical structure, but the contributions from the glossopharyngeal and vagus nerves and the superior cervical ganglion that give rise to the pharyngeal plexus are not fully understood. The pharyngeal plexus is likely to be encountered during various anterior cervical surgical procedures of the neck such as anterior cervical discectomy and fusion. Therefore, a detailed understanding of its anatomy is essential for the surgeon who operates in and around this region. Although the pharyngeal plexus is an anatomical structure that is widely mentioned in literature and anatomy books, detailed descriptions of its structural nuances are scarce; therefore, we provide a comprehensive review that encompasses all the available data from this critical structure. We conducted a narrative review of the current literature using databases like PubMed, Embase, Ovid, and Cochrane. Information was gathered regarding the pharyngeal plexus to improve our understanding of its anatomy to elucidate its involvement in postoperative spine surgery complications such as dysphagia. The neural contributions of the cranial nerves IX, X, and superior sympathetic ganglion intertwine to form the pharyngeal plexus that can be injured during ACDF procedures. Factors like surgical retraction time, postoperative hematoma, surgical hardware materials, and profiles and smoking are related to postoperative dysphagia onset. Thorough anatomical knowledge and lateral approaches to ACDF are the best preventing measures.


Asunto(s)
Trastornos de Deglución/diagnóstico , Ganglios Simpáticos/anatomía & histología , Nervio Glosofaríngeo/anatomía & histología , Músculos Faríngeos/anatomía & histología , Complicaciones Posoperatorias/diagnóstico , Nervio Vago/anatomía & histología , Vértebras Cervicales/anatomía & histología , Vértebras Cervicales/cirugía , Trastornos de Deglución/etiología , Discectomía/efectos adversos , Femenino , Ganglios Simpáticos/cirugía , Nervio Glosofaríngeo/cirugía , Humanos , Masculino , Músculos Faríngeos/inervación , Músculos Faríngeos/cirugía , Complicaciones Posoperatorias/etiología , Fusión Vertebral/efectos adversos , Nervio Vago/cirugía
3.
Clin Anat ; 34(1): 30-39, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-32315475

RESUMEN

INTRODUCTION: Three-dimensional (3D) printing of anatomical structures is a growing method of education for students and medical trainees. These models are generally produced as static representations of gross surface anatomy. In order to create a model that provides educators with a tool for demonstration of kinematic and physiologic concepts in addition to surface anatomy, a high-resolution segmentation and 3D-printingtechnique was investigated for the creation of a dynamic educational model. METHODS: An anonymized computed tomography scan of the cervical spine with a diagnosis of ossification of the posterior longitudinal ligament was acquired. Using a high-resolution thresholding technique, the individual facet and intervertebral spaces were separated, and models of the C3-7 vertebrae were 3D-printed. The models were placed on a myelography simulator and subjected to flexion and extension under fluoroscopy, and measurements of the spinal canal diameter were recorded and compared to in-vivo measurements. The flexible 3D-printed model was then compared to a static 3D-printed model to determine the educational benefit of demonstrating physiologic concepts. RESULTS: The canal diameter changes on the flexible 3D-printed model accurately reflected in-vivo measurements during dynamic positioning. The flexible model also was also more successful in teaching the physiologic concepts of spinal canal changes during flexion and extension than the static 3D-printed model to a cohort of learners. CONCLUSIONS: Dynamic 3D-printed models can provide educators with a cost-effective and novel educational tool for not just instruction of surface anatomy, but also physiologic concepts through 3D ex-vivo modeling of case-specific physiologic and pathologic conditions.


Asunto(s)
Anatomía/educación , Vértebras Cervicales/anatomía & histología , Modelos Anatómicos , Impresión Tridimensional/normas , Humanos , Imagenología Tridimensional , Osificación del Ligamento Longitudinal Posterior/diagnóstico por imagen , Impresión Tridimensional/economía , Tomografía Computarizada por Rayos X
4.
Neurocrit Care ; 32(3): 894-898, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-31332627

RESUMEN

BACKGROUND: Medical simulation for the teaching of procedural skills to health-care providers is an effective method of instruction to improve safety, quality, and procedural efficiency. There are several commercially available simulators for lumbar puncture training; however, there is currently no model available for lumbar drain intrathecal catheter placement. METHODS: A modular lumbar drain simulator was assembled with the use of a spine model, ballstical gel, and Penrose drain tubing to recreate the procedural steps and tactile feedback of a live lumbar drain insertion. RESULTS: The assembled simulator demonstrated the ability to provide users with manual feeback of a "pop" sensation when intrathecal puncture was achieved with a 14 gauge Touhy needle, as well as spontaneous CSF flow. A silastic catheter was able to be inserted into the simulated subarachnoid space in the same manner as a live procedure. CONCLUSIONS: A high-fidelity lumbar drain simulator can be constructed in a cost-effective manner. We have detailed the materials and assembly of our successful design in order to provide a novel educational tool for procedural instruction and practice.


Asunto(s)
Cateterismo , Competencia Clínica , Drenaje , Entrenamiento Simulado/métodos , Punción Espinal , Humanos , Vértebras Lumbares , Espacio Subaracnoideo
5.
Clin Anat ; 33(3): 428-430, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31885101

RESUMEN

Three-dimensional (3D) printing has revolutionized individualized medicine for patient-specific anatomical modeling and surgical planning. The surge of investigations in model creation for preoperative assessments and patient education has demonstrated improvements in both operative factors and patient satisfaction. In addition, recent technologic advances in 3D printing techniques have provided a resource to create visually pleasing models with chromatic cues for segmentation of adjacent structures. Despite these advances, an important consideration that has yet to be addressed is the quality of representation of the not only the form of structures created, but also the functional relationships of each structure. Jean François Fernel (1497-1558 AD) recognized a similar trend in anatomic innovation over 500 years ago, and sparked a series of texts that challenged the superficial anthropocentric views of the time and led to the foundation of physiologic principles that shaped modern medical philosophy. Accurately generating anatomical structures are directly related to discerning true physiologic function, and a comprehensive understanding of both is essential to hold accountability in fidelity for individualized 3D printing.


Asunto(s)
Modelación Específica para el Paciente/tendencias , Impresión Tridimensional , Humanos
6.
Clin Anat ; 33(1): 124-127, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31581311

RESUMEN

Anatomical knowledge is a key tenet in graduate medical and surgical education. Classically, these principles are taught in the operating room during live surgical experience. This puts both the learner and the patient at a disadvantage due to environment, time, and safety constraints. Educational adjuncts such as cadaveric courses and surgical skills didactics have been shown to improve resident confidence and proficiency in both anatomical knowledge and surgical techniques. However, the cost-effectiveness of these courses is a limiting factor and in many cases prevents implementation within institutional training programs. Anatomical simulation in the form of "desktop" three-dimensional (3D) printing provides a cost-effective adjunct while maintaining educational value. This article describes the anatomical and patient-centered approach that led to the establishment of our institution's 3D printing laboratory for anatomical and procedural education. Clin. Anat. 32:124-127, 2019. © 2019 Wiley Periodicals, Inc.


Asunto(s)
Anatomía/educación , Educación de Postgrado en Medicina/métodos , Imagenología Tridimensional , Modelos Anatómicos , Impresión Tridimensional , Entrenamiento Simulado/métodos , Cirugía General/educación , Humanos
7.
Clin Anat ; 33(6): 920-926, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32239547

RESUMEN

Cervical radiculopathy from uncovertebral joint (UVJ) hypertrophy and nerve root compression often occurs anterior and lateral within the cervical intervertebral foramen, presenting a challenge for complete decompression through anterior cervical approaches owing to the intimate association with the vertebral artery and associated venous plexus. Complete uncinatectomy during anterior cervical discectomy and fusion (ACDF) is a controversial topic, many surgeons relying on indirect nerve root decompression from restoration of disc space height. However, in cases of severe UVJ hypertrophy, indirect decompression does not adequately address the underlying pathophysiology of anterolateral foraminal stenosis. Previous reports in the literature have described techniques involving extensive dissection of the cervical transverse process and lateral uncinate process (UP) in order to identify the vertebral artery for safe removal of the UP. Recent anatomical investigations have detailed the microanatomical organization of the fibroligamentous complex surrounding the UP and neurovascular structures. The use of the natural planes formed from the encapsulation of these connective tissue layers provides a safe passage for lateral UP dissection during anterior cervical approaches. This can be performed from within the disc space during ACDF to avoid extensive lateral dissection. In this article, we present our 10-year experience using an anatomy-based microsurgical technique for safe and complete removal of the UP during ACDF for cervical radiculopathy caused by UVJ hypertrophy.


Asunto(s)
Descompresión Quirúrgica/métodos , Discectomía/métodos , Microcirugia/métodos , Radiculopatía/cirugía , Fusión Vertebral/métodos , Articulación Cigapofisaria/cirugía , Humanos
8.
Clin Anat ; 33(7): 1056-1061, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31837174

RESUMEN

Geniculate neuralgia (GN) is an uncommon, but severe, condition that is characterized by excruciating paroxysmal pain in the seventh cranial nerve's cutaneous distribution of general somatic afferent fibers carried through the nervus intermedius (NI). GN becomes a surgical disease in refractory cases of pain after exhaustive medical management. Surgical intervention in the form of microvascular decompression and nerve sectioning has been investigated with good patient outcomes. Despite this, there are limited guidelines on either technique's appropriateness in specific operative scenarios. In our 30-year experience in GNs surgical management, we have found that a detailed knowledge of the NIs anatomy, variants, and intraoperative surgical anatomic findings are the key to choosing the most appropriate intervention, and may provide the answer to why some patients fail to experience pain relief after surgery. These anatomic variants also may explain why many patients commonly do not experience side effects related to the visceral efferent and special afferent fibers after nerve sectioning.


Asunto(s)
Nervio Facial/anatomía & histología , Nervio Facial/cirugía , Neuralgia/cirugía , Adulto , Anciano , Dolor de Oído/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
9.
Clin Anat ; 33(3): 458-467, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31943378

RESUMEN

INTRODUCTION: Three-dimensional printing and virtual simulation both provide useful methods of patient-specific anatomical modeling for assessing and validating surgical techniques. A combination of these two methods for evaluating the feasibility of spinal instrumentation techniques based on anatomical landmarks has not previously been investigated. MATERIALS AND METHODS: Nineteen anonymized CT scans of the thoracic spine in adult patients were acquired. Maximum pedicle width and height were recorded, and statistical analysis demonstrated normal distributions. The images were converted into standard tessellation language (STL) files, and the T12 vertebrae were anatomically segmented. The intersection of two diagonal lines drawn from the lateral and medial borders of the T12 transverse process (TP) to the lateral border of the pars and inferolateral portion of the TP was identified on both sides of each segmented vertebra. A virtual screw was created and insertion into the pedicle on each side was simulated using the proposed landmarks. The vertebral STL files were then 3D-printed, and 38 pedicles were instrumented according to the individual posterior landmarks used in the virtual investigation. RESULTS: There were no pedicle breaches using the proposed anatomical landmarks for insertion of T12 pedicle screws in the virtual simulation component. The technique was further validated by additive manufacturing of individual T12 vertebrae and demonstrated no breaches or model failures during live instrumentation using the proposed landmarks. CONCLUSIONS: Ex vivo modeling through virtual simulation and 3D printing provides a powerful and cost-effective means of replicating vital anatomical structures for investigation of complex surgical techniques.


Asunto(s)
Puntos Anatómicos de Referencia , Imagenología Tridimensional , Tornillos Pediculares , Impresión Tridimensional , Vértebras Torácicas/anatomía & histología , Vértebras Torácicas/cirugía , Adulto , Anciano , Diseño Asistido por Computadora , Femenino , Humanos , Masculino , Persona de Mediana Edad , Vértebras Torácicas/diagnóstico por imagen , Tomografía Computarizada por Rayos X
10.
Catheter Cardiovasc Interv ; 93(3): 428-433, 2019 02 15.
Artículo en Inglés | MEDLINE | ID: mdl-30311400

RESUMEN

BACKGROUND: There are limited options for percutaneous mechanical circulatory support (pMCS) in patients requiring high-risk percutaneous coronary intervention. OBJECTIVES: This first-in-human, single-center study aimed to evaluate the safety and feasibility of a novel pMCS device in high-risk percutaneous coronary intervention patients. METHODS: Aortix (Procyrion, Houston, Texas) is a pMCS device deployed in the descending aorta via the femoral artery that uses axial flow to provide cardiac unloading and augment renal and systemic perfusion. We assessed the use and effect of the Aortix device in six patients undergoing high-risk PCI. All patients had impaired left ventricular function, complex coronary disease, renal dysfunction, and suitable iliofemoral anatomy for Aortix placement via transfemoral approach. We recorded periprocedural events including hemodynamic effects of the device on cardiac output and urine output. We then followed patients up to 30 days following the PCI procedure for adverse events. RESULTS: Aortix delivery (18 Fr sheath) took 4-9 min, mean support time was 70 (range 47-95) min, and mean flow rate through the device was 3.5 L/min. During support, mean rate of urine output increased 10-fold (range 2.5-25.0x). Estimated GFR improved at discharge compared with baseline (mean increase 6.95 ± 8.09 mL/min). There were no device failures and PCI was successful in all patients. Aortix was removed and hemostasis was achieved with a vascular closure device and manual pressure. No patients experienced adverse events or hemodynamic compromise. No clinically significant hemolysis occurred (mean LDH 239.2 ± 73.6 mU/mL at baseline and 206.4 ± 82.2 mU/mL at discharge). No vascular access complications were observed. CONCLUSIONS: Aortix, a novel pMCS device, was successfully deployed and retrieved in all initial patients undergoing high-risk PCI. We noted no significant hemolysis with temporary use of this axial flow device. Improvement in eGFR suggests a potential renal protective effect and is an important area for future investigation in patients with impaired left ventricular function and renal dysfunction.


Asunto(s)
Aorta/fisiopatología , Enfermedad de la Arteria Coronaria/terapia , Corazón Auxiliar , Intervención Coronaria Percutánea , Implantación de Prótesis/instrumentación , Disfunción Ventricular Izquierda/terapia , Anciano , Enfermedad de la Arteria Coronaria/diagnóstico , Enfermedad de la Arteria Coronaria/fisiopatología , Circulación Coronaria , Remoción de Dispositivos , Estudios de Factibilidad , Femenino , Tasa de Filtración Glomerular , Hemodinámica , Humanos , Riñón/fisiopatología , Enfermedades Renales/fisiopatología , Masculino , Persona de Mediana Edad , Paraguay , Intervención Coronaria Percutánea/efectos adversos , Estudios Prospectivos , Diseño de Prótesis , Implantación de Prótesis/efectos adversos , Recuperación de la Función , Flujo Sanguíneo Regional , Circulación Renal , Factores de Riesgo , Factores de Tiempo , Resultado del Tratamiento , Micción , Disfunción Ventricular Izquierda/diagnóstico , Disfunción Ventricular Izquierda/fisiopatología , Función Ventricular Izquierda
11.
Acta Neurochir (Wien) ; 161(10): 2229-2232, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31402419

RESUMEN

BACKGROUND: Cervical radiculopathy from uncovertebral joint hypertrophy and foraminal stenosis is a common indication for anterior cervical diskectomy and fusion (ACDF). Often, the uncinate hypertrophy extends lateral to the foramen and impinges on the nerve close to the vertebral artery as it travels in between the transverse foramina. METHOD: Using an injected cadaveric specimen to highlight the vital neurovascular and bony structures pertinent to this procedure, we demonstrate the technical details of complete uncinatectomy for cervical foraminal stenosis. CONCLUSION: Total uncinatectomy is a useful adjunct during ACDF for complete foraminal decompression in cases of uncovertebral joint hypertrophy.


Asunto(s)
Vértebras Cervicales/cirugía , Discectomía/métodos , Radiculopatía/cirugía , Fusión Vertebral/métodos , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/patología , Humanos , Hipertrofia/diagnóstico por imagen , Hipertrofia/cirugía , Posicionamiento del Paciente , Radiculopatía/diagnóstico por imagen , Resultado del Tratamiento
12.
Acta Neurochir (Wien) ; 161(12): 2429-2431, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31696301

RESUMEN

BACKGROUND: Posterior instrumentation techniques are commonly employed for cervicothoracic fixation. The pedicles of the upper thoracic vertebrae can typically accommodate larger diameter screws than the subaxial cervical vertebrae. In many construct systems, this requires the use of a tapered rod, which can be technically challenging to place. METHOD: Using a three-dimensionally printed biomimetic spine simulator, we illustrate the stepwise process of instrumentation and tapered rod placement across the cervicothoracic junction (CTJ). CONCLUSION: Tapered rod systems can augment the biomechanical stability of cervicothoracic constructs. Ease of rod placement across the CTJ hinges upon a systematic method of instrumentation.


Asunto(s)
Clavos Ortopédicos , Vértebras Cervicales/cirugía , Fusión Vertebral/métodos , Vértebras Torácicas/cirugía , Fenómenos Biomecánicos , Cadáver , Humanos , Fusión Vertebral/instrumentación
13.
J Nurs Adm ; 49(11): 531-537, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31651612

RESUMEN

OBJECTIVE: This study explored the relationships between nurse-sensitive structures, processes (work engagement [WE], frequency of fall risk discussion during report, and frequency of purposeful rounds), and patient falls. BACKGROUND: Strong WE is associated with better nurse-assessed quality of care, but previous research is limited by self-reported outcome measures. METHODS: We used a descriptive, cross-sectional, survey design with 41 nursing units from 7 hospitals. Nurses completed a survey including the Utrecht Work Engagement Scale. National Database of Nursing Quality Indicators reports provided falls data. RESULTS: WE was not related to patient falls, even after controlling for RN staffing and skill mix. The nursing units that had more nurses performing frequent purposeful rounds experienced greater falls with injury. Highly engaged nurses participated more in purposeful rounding and discussion of fall risk during bedside report than less engaged nurses. CONCLUSIONS: Further research is needed to understand the impact of WE on patient outcomes.


Asunto(s)
Accidentes por Caídas/prevención & control , Atención de Enfermería/normas , Personal de Enfermería en Hospital/psicología , Guías de Práctica Clínica como Asunto , Administración de la Seguridad/normas , Lugar de Trabajo/normas , Adulto , Estudios Transversales , Femenino , Humanos , Persona de Mediana Edad
14.
Oper Neurosurg (Hagerstown) ; 24(6): e414-e420, 2023 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-36656028

RESUMEN

BACKGROUND: Anterior approaches to the cervical spine are among the most common exposures by which neurosurgeons and orthopedic surgeons access the prevertebral space and ultimately the cervical disk and vertebral bodies. There is a paucity of literature describing the microanatomic fascial planes of the neck with respect to anterior cervical approaches. OBJECTIVE: To delineate the microanatomic connections of the cervical fascial planes pertinent to anterior cervical exposure. METHODS: Using a cadaveric model, original illustrations, the Visible Human Project, and an original surgical video, we demonstrate a stepwise method for identifying the correct planes for anterior cervical exposure. RESULTS: A step-by-step method for identifying the anterior cervical fascial planes intraoperatively is demonstrated. CONCLUSION: A comprehensive understanding of anterior cervical microsurgical anatomy is vital for performing a methodical yet efficient approach to the prevertebral space while minimizing retraction and iatrogenic injury to the surrounding neurovascular structures.


Asunto(s)
Vértebras Cervicales , Cuello , Humanos , Vértebras Cervicales/cirugía , Vértebras Cervicales/anatomía & histología , Cuello/cirugía , Disección
15.
Oper Neurosurg (Hagerstown) ; 24(2): 201-208, 2023 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-36637305

RESUMEN

BACKGROUND: Graduate surgical education is highly variable across regions and institutions regarding case volume and degree of trainee participation in each case. Dedicated educational curriculum using cadaveric tissue has been shown to enhance graduate surgical training, however with associated financial and utility burden to the institution. OBJECTIVE: To investigate the utility of educational and cost applications of a novel method of combining mixed organic hydrogel polymers and 3-dimensional printed anatomic structures to create a complete "start-to-finish" simulation for resident education in spinal anatomy, instrumentation, and surgical techniques. METHODS: This qualitative pilot study investigated 14 international participants on achievement of objective and personal learning goals in a standardized curriculum using biomimetic simulation compared with cadaveric tissue. A questionnaire was developed to examine trainee evaluation of individual anatomic components of the biomimetic simulators compared with previous experience with cadaveric tissue. RESULTS: A total of 210 responses were acquired from 14 participants. Six participants originated from US residency education programs and 8 from transcontinental residency programs. Survey results for the simulation session revealed high user satisfaction. Score averages for each portion of the simulation session indicated learner validation of anatomic features for the simulation compared with previous cadaveric experience. Cost analysis resulted in an estimated savings of $10 833.00 for this single simulation session compared with previous cadaveric tissue sessions. CONCLUSION: The results of this study indicate a strong potential of establishing biomimetic simulation as a cost-effective and high-quality alternative to cadaveric tissue for the instruction of fundamental spine surgical techniques.


Asunto(s)
Internado y Residencia , Humanos , Proyectos Piloto , Educación de Postgrado en Medicina/métodos , Curriculum , Cadáver
16.
Clin Spine Surg ; 2023 Sep 05.
Artículo en Inglés | MEDLINE | ID: mdl-37684726

RESUMEN

STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To perform a systematic review of the clinical symptoms, radiographic findings, and outcomes after spinal decompression in B-cell lymphoma. SUMMARY OF BACKGROUND DATA: B-cell lymphoma is a potential cause of spinal cord compression that presents ambiguously with nonspecific symptoms and variable imaging findings. Surgical decompression is a mainstay for both diagnosis and management, especially in patients with acute neurological deficits; however, the efficacy of surgical intervention compared with nonoperative management is still unclear. METHODS: The databases of Medline, PubMed, and the Cochrane Database of Systemic Reviews were queried for all articles reporting spinal B-cell lymphoma. Data on presenting symptoms, treatments, survival outcomes, and histologic markers were extracted. Using the R software "survival" package, we generated bivariate and multivariate Cox survival regression models and Kaplan-Meier curves. RESULTS: In total, 65 studies were included with 72 patients diagnosed with spinal B-cell lymphoma. The mean age was 56.22 (interquartile range: 45.00-70.25) with 68% of patients being males and 4.2% of patients being immunocompromised. Back pain was the most common symptom (74%), whereas B symptoms and cauda equina symptoms were present in 6% and 29%, respectively. The average duration of symptoms before presentation was 3.81 months (interquartile range: 0.45-3.25). The most common location was the thoracic spine (53%), with most lesions being hyperintense (28%) on T2 magnetic resonance imaging. Surgical resection was performed in 83% of patients. Symptoms improved in 91% of patients after surgery and in 80% of patients treated nonoperatively. For all 72 patients, the overall survival at 1 and 5 years was 85% (95% CI: 0.749-0.953; n = 72) and 66% (95% CI: 0.512-0.847; n = 72), respectively. CONCLUSION: Although surgery is usually offered in patients with acute spinal cord compression from B-cell lymphoma, chemotherapy and radiation alone offer a hopeful alternative to achieve symptomatic relief, particularly in patients who are unable to undergo surgery.

17.
Cureus ; 15(7): e41765, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37575766

RESUMEN

Carotid body tumors (CBTs) are rare neoplasms of the neuroectoderm accounting for 0.6% of head and neck tumors, with a 2%-12.5% risk of malignancy. While surgical resection has been associated with a high rate of neurologic and vascular complications, it remains the mainstay of treatment for malignant CBTs. We present the case of a 40-year-old female with a 5-year history of progressively enlarging right-sided neck mass, with MRI and MRA showing a Shamblin grade III CBT encasement of the internal carotid artery (ICA). Blood flow was absent in the petrous segment of ICA, with great collateralization of brain blood supply, enabling en bloc resection of the tumor with a carotid bulb and ligation of the common carotid artery (CCA) without vascular reconstruction. Further, we describe the characteristics and current management for malignant CBTs, including surgical management, pre-surgical embolization, and adjuvant radiation therapy.

18.
J Neurosurg Spine ; 38(1): 91-97, 2023 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-36029261

RESUMEN

OBJECTIVE: There is a paucity of literature on pelvic fixation failure after adult spine surgery in the early postoperative period. The purpose of this study was to determine the incidence of acute pelvic fixation failure in a large single-center study and to describe the lessons learned. METHODS: The authors performed a retrospective review of adult (≥ 18 years old) patients who underwent spinal fusion with pelvic fixation (iliac, S2-alar-iliac [S2AI] screws) at a single academic medical center between 2015 and 2020. All patients had a minimum of 3 instrumented levels. The minimum follow-up was 6 months after the index spine surgery. Patients with prior pelvic fixation were excluded. Acute pelvic fixation failure was defined as revision of the pelvic screws within 6 months of the primary surgery. Patient demographics and operative, radiographic, and rod/screw parameters were collected. All rods were cobalt-chrome. All iliac and S2AI screws were closed-headed screws. RESULTS: In 358 patients, the mean age was 59.5 ± 13.6 years, and 64.0% (n = 229) were female. The mean number of instrumented levels was 11.5 ± 5.5, and 79.1% (n = 283) had ≥ 6 levels fused. Three-column osteotomies were performed in 14.2% (n = 51) of patients, and 74.6% (n = 267) had an L5-S1 interbody fusion. The mean diameter/length of pelvic screws was 8.5/86.6 mm. The mean number of pelvic screws was 2.2 ± 0.5, the mean rod diameter was 6.0 ± 0 mm, and 78.5% (n = 281) had > 2 rods crossing the lumbopelvic junction. Accessory rods extended to S1 (32.7%, n = 117) or S2/ilium (45.8%, n = 164). Acute pelvic fixation failure occurred in 1 patient (0.3%); this individual had a broken S2AI screw near the head-neck junction. This 76-year-old woman with degenerative lumbar scoliosis and chronic lumbosacral zone 1 fracture nonunion had undergone posterior instrumented fusion from T10 to pelvis with bilateral S2AI screws (8.5 × 90 mm); i.e., transforaminal lumbar interbody fusion L4-S1. The patient had persistent left buttock pain postoperatively, with radiographically confirmed breakage of the left S2AI screw 68 days after surgery. Revision included instrumentation removal at L2-pelvis and a total of 4 pelvic screws. CONCLUSIONS: The acute pelvic fixation failure rate was exceedingly low in adult spine surgery. This rate may be the result of multiple factors including the preference for multirod (> 2), closed-headed pelvic screw constructs in which large-diameter long screws are used. Increasing the number of rods and screws at the lumbopelvic junction may be important factors to consider, especially for patients with high risk for nonunion.


Asunto(s)
Escoliosis , Fusión Vertebral , Humanos , Adulto , Femenino , Persona de Mediana Edad , Anciano , Adolescente , Masculino , Tornillos Óseos , Pelvis/cirugía , Ilion/cirugía , Escoliosis/cirugía , Osteotomía , Fusión Vertebral/efectos adversos , Sacro/diagnóstico por imagen , Sacro/cirugía
19.
J Neurosurg Spine ; 38(2): 208-216, 2023 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-36242579

RESUMEN

OBJECTIVE: The purpose of this study was to determine the incidence, mechanism, and potential protective strategies for pelvic fixation failure (PFF) within 2 years after adult spinal deformity (ASD) surgery. METHODS: Data for ASD patients (age ≥ 18 years, minimum of six instrumented levels) with pelvic fixation (S2-alar-iliac [S2AI] and/or iliac screws) with a minimum 2-year follow-up were consecutively collected (2015-2019). Patients with prior pelvic fixation were excluded. PFF was defined as any revision to pelvic screws, which may include broken rods across the lumbosacral junction requiring revision to pelvic screws, pseudarthrosis across the lumbosacral junction requiring revision to pelvic screws, a broken or loose pelvic screw, or sacral/iliac fracture. Patient information including demographic data and health history (age, sex, BMI, smoking status, American Society of Anesthesiologists score, osteoporosis), operative (total instrumented levels [TIL], three-column osteotomy [3CO], interbody fusion), screw (iliac, S2AI, length, diameter), rod (diameter, kickstand), rod pattern (number crossing lumbopelvic junction, lowest instrumented vertebra [LIV] of accessory rod[s], lateral connectors, dual-headed screws), and pre- and postradiographic (lumbar lordosis, pelvic incidence, pelvic tilt, major Cobb angle, lumbosacral fractional curve, C7 coronal vertical axis [CVA], T1 pelvic angle, C7 sagittal vertical axis) parameters was collected. All rods across the lumbosacral junction were cobalt-chrome. All iliac and S2AI screws were closed-headed tulips. Both univariate and multivariate analyses were performed to determine risk factors for PFF. RESULTS: Of 253 patients (mean age 58.9 years, mean TIL 13.6, 3CO 15.8%, L5-S1 interbody 74.7%, mean pelvic screw diameter/length 8.6/87 mm), the 2-year failure rate was 4.3% (n = 11). The mechanisms of failure included broken rods across the lumbosacral junction (n = 4), pseudarthrosis across the lumbosacral junction requiring revision to pelvic screws (n = 3), broken pelvic screw (n = 1), loose pelvic screw (n = 1), sacral/iliac fracture (n = 1), and painful/prominent pelvic screw (n = 1). A higher number of rods crossing the lumbopelvic junction (mean 3.8 no failure vs 2.9 failure, p = 0.009) and accessory rod LIV to S2/ilium (no failure 54.2% vs failure 18.2%, p = 0.003) were protective for failure. Multivariate analysis demonstrated that accessory rod LIV to S2/ilium versus S1 (OR 0.2, p = 0.004) and number of rods crossing the lumbar to pelvis (OR 0.15, p = 0.002) were protective, while worse postoperative CVA (OR 1.5, p = 0.028) was an independent risk factor for failure. CONCLUSIONS: The 2-year PFF rate was low relative to what is reported in the literature, despite patients undergoing long fusion constructs for ASD. The number of rods crossing the lumbopelvic junction and accessory rod LIV to S2/ilium relative to S1 alone likely increase construct stiffness. Residual postoperative coronal malalignment should be avoided to reduce PFF.


Asunto(s)
Lordosis , Seudoartrosis , Fusión Vertebral , Humanos , Adulto , Persona de Mediana Edad , Adolescente , Seudoartrosis/diagnóstico por imagen , Seudoartrosis/epidemiología , Seudoartrosis/etiología , Vértebras Lumbares/diagnóstico por imagen , Vértebras Lumbares/cirugía , Pelvis/cirugía , Lordosis/diagnóstico por imagen , Lordosis/cirugía , Lordosis/etiología , Tornillos Óseos , Sacro/diagnóstico por imagen , Sacro/cirugía , Ilion/diagnóstico por imagen , Ilion/cirugía , Fusión Vertebral/efectos adversos
20.
Cureus ; 14(8): e28577, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36185845

RESUMEN

Syringomyelia and syringobulbia continue to remain a diagnosis without widely accepted treatment paradigms. Furthermore, the currently available treatment options can be complicated by delayed symptom recurrence and the need for revision surgery. Revision intradural surgery is challenging, and currently, there is a paucity of literature describing safe techniques for revision syringotomy and shunt placement. In this technical report, we present a surgical video describing the technique of revision syringo-subarachnoid shunt placement in a 61-year-old female with a history of multiple intradural surgeries who presented with progressively symptomatic ascending syringobulbia.

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