How compassionate use enabled Israel to deliver the Pfizer-BioNTech COVID-19 vaccination to vulnerable children aged 12-15 years before regulatory approval.

AIM: This paper describes the emergency, compassionate use of the COVID-19 vaccination for high-risk adolescents aged 12-15 years prior to approval by the American Food and Drugs Administration in May 2021. The target audience had underlying health conditions associated with severe disease and multisystem inflammatory syndrome in children (MIS-C) or severely immunosuppressed household members. METHODS: An orderly approval system was established in Israel for adolescents aged 12-15 years, based on a professional position paper and compassionate treatment regulations. From 12 February 2021, eligible adolescents were referred to the Israeli Ministry of Health for permission to vaccinate, via four health maintenance organisations. Data were collected about adverse events after vaccinations and the incidence of any cases of COVID-19. RESULTS: By 15 March 2021, the vaccine had been approved for 607 adolescents: 333 had received one dose, and 92 had received two doses. The median age was 14.6 years, and the major indication was obesity. Only one child tested positive for the virus, 4 days after vaccination, and no adverse effects were recorded. CONCLUSION: The emergency use of COVID-19 vaccination for 333 adolescents aged 12-15, 92 of them with 2 doses, based on a position paper and compassionate treatment regulations, did not result in any adverse effects. Since 27 July 2021, the same process was further applied in Israel among younger children, aged 5-11, preceding formal release of the clinical trial.

A large multi-country outbreak of monkeypox across 41 countries in the WHO European Region, 7 March to 23 August 2022.

Following the report of a non-travel-associated cluster of monkeypox cases by the United Kingdom in May 2022, 41 countries across the WHO European Region have reported 21,098 cases and two deaths by 23 August 2022. Nowcasting suggests a plateauing in case notifications. Most cases (97%) are MSM, with atypical rash-illness presentation. Spread is mainly through close contact during sexual activities. Few cases are reported among women and children. Targeted interventions of at-risk groups are needed to stop further transmission.

Predictors of Involvement and Warmth of Custodial Fathers in Israel: Comparison with Married and Noncustodial Divorced Fathers.

This study compared the levels and predictors of paternal warmth and involvement of 218 custodial fathers to 222 married fathers and 105 noncustodial (NC) divorced fathers in Israel. The examined predictors were fathers' perceptions of their own fathers; their own caregiving behaviors and parental self-efficacy; and child characteristics and coparental coordination. Results indicated that being a custodial father was associated with more involvement than being a married or NC divorced father. Regression analyses revealed that experience of care with own father predicted fathers' involvement, whereas own father control was related to lower paternal warmth. Lower avoidant caregiving and high paternal self-efficacy predicted both paternal involvement and warmth, whereas perceiving the child as more difficult predicted lower paternal warmth. Higher levels of coparental coordination were associated with more paternal involvement, whereas low coparental coordination was associated with less involvement, primarily among NC divorced fathers. These interactions highlight the distinct paternal behavior of custodial fathers. Unlike married and NC divorced fathers, they showed more warmth, regardless of their avoidant caregiving. Results are discussed in light of the different roles played by fathers in the three groups.

Young adult sibling relations: the effects of perceived parental favoritism and narcissism.

The present study examined predictors of siblings' relations in 202 young adults (aged 21-32 years), who completed the Adult Sibling Relationship Questionnaire and the Narcissistic Personality Inventory. Results indicate that warmth between siblings is explained by gender (with women feeling closer), perceived paternal favoritism, low levels of narcissism, and an interaction suggesting that paternal favoritism moderates the link between narcissism and sibling warmth. Conflict between siblings was explained by gender (sisters), age, parental favoritism, high levels of narcissism, extreme levels of similarity or dissimilarity between siblings, and interactions indicating that older age is a predictor of conflict between siblings among women but not among men. The impact of parental favoritism and narcissism on sibling relationships in young adulthood was discussed.

Forgiveness in late life.

This study expands the understanding of forgiveness among a sample of older adults in Israel by exploring the contributory roles of meaning in life; stressful life events; and socio economic variables such as gender, age, and religiosity as well as time and agent of hurt. A convenience sample of 225 older adults in Israel responded to the Enright Forgiveness Inventory and the Reker Meaning in Life Scale. An additional questionnaire contained demographic and other background information, including a list of traumatic life events. The results of our study support our assumption that meaning in life correlates with forgiveness on all its dimensions. Furthermore, women tend to forgive more than men, and there is a tendency to forgive family members more readily than nonfamily members, and people who are still alive, as opposed to those who have passed away.

Adjustment to divorce: a preliminary study among Muslim Arab citizens of Israel.

Adjustment to divorce in a sample of 312 Muslim Arab citizens of Israel was associated both with variables that have been shown to affect adjustment to divorce in Western societies and with variables specific to the culture of the study. The former included male gender, education, current employment, fewer accompanying stressors, and greater satisfaction with the divorce process. The latter were the respondents' self-defined modernity (as opposed to traditionalism) and their disinclination to perceive divorced persons as bad parents and spouses and as socially deviant, in accord with the social stereotype of their community.

The drug-user husband and his wife: attachment styles, family cohesion, and adaptability.

This study which assesses the association between the attachment styles of drug-user husbands (n = 56) and their wives (n = 56) and their perceptions of family dynamics was conducted in 1998. The population study included heroin (52.9%) and multidrug detoxified outpatients. All subjects completed the Adult Attachment Style Scale and the FACES III. Results indicated that the perceptions of family adaptability and cohesion among the drug-user husbands and their wives did not differ from the Israeli norm. Most of the drug users (60.7%) were characterized by the avoidant attachment style, followed by the secure style (26.8%), and the anxious/ambivalent style (12.5%). Half the wives (53.6%) were characterized by the secure style, followed by the avoidant style (42.9%) and the anxious/ambivalent style (3.6%). A secure style in husband and wife was associated with higher levels of family cohesion and adaptability, and the anxious/ambivalent style with a lower perception of family cohesion and adaptability. These findings have important implications for rehabilitation prospects and for planning intervention programs.