RESUMEN
BACKGROUND: Whole breast irradiation reduces loco-regional recurrence and risk of death in patients submitted to breast-conserving treatment. Data show that radiation to the index quadrant alone may be enough in selected patients. AIM: To report the experience with intra-operative radiotherapy (IORT) with Electron-beam Cone in Linear Accelerator (ELIOT) and the results in overall survival, local control and late toxicity of patients submitted to this treatment. MATERIALS AND METHODS: 147 patients treated with a median follow up of 6.9 years (0.1⿿11.5 years). The actuarial local control and overall survival probabilities were estimated using the Kaplan Meier method. All tests were two-sided and p ⿤ 0.05 was considered statistically significant. RESULTS: Overall survival of the cohort in 5 years, in the median follow up and in 10 years was of 98.3%, 95.1% and 95.1%, respectively, whereas local control in 5 years, in the median follow up and in 10 years was of 96%, 94.9% and 89.5%, respectively. Two risk groups were identified for local recurrence depending on the estrogen or progesterone receptors, axillary or margin status and lymphovascular invasion (LVI) (p = 0.016). CONCLUSIONS: IORT is a safe and effective treatment. Rigorous selection is important to achieve excellent local control results.
RESUMEN
O carcinoma espinocelular representa 20 por cento a 25 por cento dos casos de câncer de pele na população branca mundial. Os autores relatam um caso de carcinoma espinocelular localizado no complexo papiloareolar em um paciente do sexo masculino, cuja apresentação clínica era uma lesão ulcerada com invasão do parênquima mamário subjacente. O paciente foi submetido a mastectomia radical modificada à Patey. O diagnóstico diferencial com doença de Paget da mama deve ser lembrado.