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1.
Sensors (Basel) ; 24(10)2024 May 20.
Artículo en Inglés | MEDLINE | ID: mdl-38794101

RESUMEN

With recent advances in vehicle technologies, in-vehicle networks (IVNs) and wiring harnesses are becoming increasingly complex. To solve these challenges, the automotive industry has adopted a new zonal-based IVN architecture (ZIA) that connects electronic control units (ECUs) according to their physical locations. In this paper, we evaluate how the number of zones in the ZIA affects the end-to-end (E2E) delay and the characteristics of the wiring harnesses. We evaluate the impact of the number of zones on E2E delay through the OMNeT++ network simulator. In addition, we theoretically predict and analyze the impact of the number of zones on the wiring harnesses. Specifically, we use an asymptotic approach to analyze the total length and weight evolution of the wiring harnesses in ZIAs with 2, 4, 6, 8, and 10 zones by incrementally increasing the number of ECUs. We find that as the number of zones increases, the E2E delay increases, but the total length and weight of the wiring harnesses decreases. These results confirm that the ZIA effectively uses the wiring harnesses and mitigates network complexity within the vehicle.

2.
Sensors (Basel) ; 23(5)2023 Feb 27.
Artículo en Inglés | MEDLINE | ID: mdl-36904829

RESUMEN

Recently, with the continuous increase in the number of sensors, motors, actuators, radars, data processors and other components carried by humanoid robots, the integration of electronic components within a humanoid is also facing new challenges. Therefore, we focus on the development of sensor networks suitable for humanoid robots to designing an in-robot network (IRN) that can support a large sensor network for reliable data exchange. It was shown that the domain based in-vehicle network (IVN) architectures (DIA) used in the traditional and electric vehicles is gradually moving towards zonal IVN architectures (ZIA). Compared with DIA, ZIA for vehicles is known to provide better network scalability, maintenance convenience, shorter harness length, lighter harness weight, lower data transmission delay, and other several advantages. This paper introduces the structural differences between ZIRA and the domain based IRN architecture (DIRA) for humanoids. Additionally, it compares the differences in the length and weight of wiring harnesses of the two architectures. The results show that as the number of electrical components including sensors increases, ZIRA reduces at least 16% compared to DIRA, the wiring harness length, weight, and its cost.

3.
Psychometrika ; 2024 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-38429494

RESUMEN

Multidimensional item response theory (MIRT) models have generated increasing interest in the psychometrics literature. Efficient approaches for estimating MIRT models with dichotomous responses have been developed, but constructing an equally efficient and robust algorithm for polytomous models has received limited attention. To address this gap, this paper presents a novel Gaussian variational estimation algorithm for the multidimensional generalized partial credit model. The proposed algorithm demonstrates both fast and accurate performance, as illustrated through a series of simulation studies and two real data analyses.

4.
Poult Sci ; 101(4): 101708, 2022 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-35150940

RESUMEN

Adiponectin can participate in the regulation of glucose and lipid metabolism, energy regulation, immune response, resistance to inflammation, oxidative stress, and apoptosis. Studies in rodents demonstrated that the small molecule compound adiponectin receptor agonist AdipoRon could activate the adiponectin receptor and played the same biological role as adiponectin. To explore the influence and regulation of AdipoRon on lipid metabolism disorder in Huoyan goose liver, in this study, goslings were fed a high-fat diet and then administered different dosages of AdipoRon. Subsequently, goose body weight, liver index, liver histopathological changes, blood glucose, blood and liver lipid, biochemical indexes related to liver function and oxidative stress, and the expression levels of genes related to lipid metabolism, inflammation, apoptosis, and autophagy, adiponectin and its receptors, key molecules of adiponectin involved signal pathway, and transcription factors in the liver, were detected using H&E and Oil red O staining, ELISA, and qRT-PCR methods. The results indicated that AdipoRon could alter the expression of lipid metabolism-related genes, inflammatory factors, apoptosis and autophagy genes, and adiponectin and its receptor genes in liver tissues through signaling pathways such as AMPK and p38 MAPK, as well as the involvement of transcription factors such as PPARα, PPARγ, SIRT1, and FOXO1, reduce the lipid content in blood and liver tissues of geese fed high-fat diets, improve liver antioxidant capacity, regulate apoptosis and autophagy of hepatocytes, and reduce liver inflammatory injury. Our study suggests that AdipoRon has a protective effect on fatty liver injury in goslings fed a high-fat diet.


Asunto(s)
Dieta Alta en Grasa , Receptores de Adiponectina , Adiponectina/genética , Adiponectina/metabolismo , Animales , Pollos/metabolismo , Dieta Alta en Grasa/efectos adversos , Dieta Alta en Grasa/veterinaria , Gansos/metabolismo , Inflamación/veterinaria , Lípidos , Hígado/metabolismo , Piperidinas , Receptores de Adiponectina/genética , Factores de Transcripción
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