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Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments.
Nucleic Acids Res
; 32(15): e121, 2004 Aug 25.
Artículo
en Inglés
| MEDLINE
| ID: mdl-15329383
RESUMEN
We have developed a method for genomic representation using Type IIB restriction endonucleases. Representation by concatenation of restriction digests, or RECORD, is an approach to sample the fragments generated by cleavage with these enzymes. Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction.