[Analysis of the working population applying to the clinic for the psycological job environmental discomfort relating to employment at AUSL of Romagna - Rimini]. / Analisi della popolazione lavorativa afferente all'ambulatorio per il Disagio psicologico nell'Ambiente di Lavoro dell'AUSL della Romagna - Sede di Rimini.

OBJECTIVES: The Occupational Physician in accordance with the Prevention and Protection of AUSL Romagna (Rimini) has enabled for some years, a Clinic for the psychological job environmental discomfort addressed to employment, with expressions of the psychophysical disorders, caused by work related stress. Health is defined by the current legislation as a state of psychophysical and social wellbeing. METHODS: The main purpose of Clinic for the psychological distress in working environment is to provide listening space and psychological support for employees. In order to assure this support, the Occupational Physician can activate the collaboration with the Psychologist of Clinic for the Psychological Evaluation in support to the formulation of the fitness for work. RESULTS: The data analyzed are those in the period between November 2010 and 2014, concerning the accesses to the Clinic for the psychological distress in working environment and in order to the developments of the paths undertaken by the workers. CONCLUSIONS: The Clinic for the psychological distress in working environment represents an effort into the individual improvement and a possible answer to the reckoning of the risk for work related stress.

Occupational exposure to antineoplastic drugs in seven Italian hospitals: the effect of quality assurance and adherence to guidelines.

In health care facilities, dermal contact and inhalation are considered to be the main routes of exposure to cytotoxic antineoplastic drugs (ADs). Hand-to-mouth contamination or accidental needle sticks as well as events due to inadequate disposal may also contribute to exposure. In order to measure the extent of contamination, biological and environmental monitoring are essential tools for routine testing. Moreover, reliable sampling and analytical procedures are required. During the last decade, several methods have been developed and validated. The appropriate analytical techniques were used to quantify even very low levels of some of the more commonly used ADs, such as cyclophosphamide, 5-fluoruracil, taxol, anthracyclines, and platinum-compounds. The main objective of this study is to assess the adherence to existing standards of practice through an effective monitoring program, including environmental and biological measurements. In seven hospitals located in Northern-Central Italy, periodic surveys were scheduled to verify continuing compliance with guidelines over a 5-year period. All biological samples were found to be below detection limits and a progressive, significant decrease in workplace contamination was observed. Our results confirm that a cost-effective monitoring regime, including fast and simple sample pre-treatment procedures, simultaneous determination of the analytes and their metabolites, validated procedures including uncertainty evaluation, and periodic surveys, is the adequate approach for the collection of reliable exposure data and hence for effective intervention.