Effects of 2,4-dichlorophenoxy acetic acid dimethyl amine salt on dental hard tissue formation in rats.

2,4-Dichlorophenoxy acetic acid dimethyl amine salt (2,4-D DMA), as one of the phenoxy acids, is used as a herbicide mainly against broad-leaf weeds in cereal crops, sugar cane, and on turf, pasture, and non-crop land. Some formulations of 2,4-D may be contaminated with dioxins. Recently, it has been shown that chlorinated organic compounds, dioxins, and furans are present in mother's milk and may cause developmental defects in children's teeth. Therefore, we aimed to evaluate the effects of 2,4-D DMA on odontogenesis in rats. 2,4-D DMA was given orally combined with rat food to pregnant albino rats. Each group consisted of two pregnant rats and, 0 (control, group A), 25 ppm (group B), 50 ppm (group C), and 100 ppm (group D) 2,4-D DMA was given to each pregnant rat as daily intake. 2,4-D DMA affected young rat's dental development and dose-related findings were found in experimental groups. The odontoblast layer was irregular and globular dentin formation was present in Groups B, C, and D but not in the control group. Thickness of enamel decreased in Groups C and D. The results of the study have shown that 2,4-D DMA could disturb dental development in rats even in relatively low doses. It is concluded that environmental contaminants such as chlorinated organic pesticides may play an important role in infant's dental development when taken via mother's milk.

Verification and comparison of a fast fourier transform-based full diffraction method for tilted and offset planes.

The recent introduction of a fast Fourier transform- (FFT-) based method for calculating the Rayleigh-Sommerfeld full diffraction integral for tilted and offset planes permits high-speed evaluation of integrated optical systems. An important part of introducing a new calculational tool is its validation and an assessment of its limitations. The validity of the new FFT-based method was determined by comparison of that method with direct integration (DI) of the Rayleigh-Sommerfeld integral, a well-established method. Points of comparison were accuracy, computational speed, memory requirements of the host computer, and applicability to various optical modeling situations. The new FFT-based method is 228 times faster, yet requires 14 times more memory, than the DI method for a 500 mum by 500 mum real computational window.

Cost, performance, and reliability simulator for optical transceiver modules.

The program couple combines simulators for optical performance, mechanical reliability, and production cost under a graphical-user interface to design, simulate, and evaluate micro-optomechanical structures. The thermal simulator predicts the package temperature distribution on the basis of the materials and the geometry as well as on heat sources, sinks, and boundary conditions. The thermal distribution is input to the mechanical simulator, which calculates the stresses or strains and displacements caused by differential thermal expansion. The optical simulator predicts the impact on the optical efficiency and the cross talk of mechanical and optical parameter variations such as solder heights, misalignments, and wavelength distributions. The cost simulator represents the manufacturing process flow and calculates the final cost and the cost sensitivity on basis of the cost and the yield of each process step. By means of balancing detector and coupling yield, cosimulation from optical to cost domains determines the optimum detector size to produce the lowest-cost transceiver module.