[A case of intestinal occlusion caused by a Meckel' diverticulum (etiopathogenetic, diagnostic and clinical considerations)]. / Su di un caso di occlusione intestinale da diverticolo di Meckel (Considerazioni etiopatogenetiche, diagnostiche e cliniche).

The authors show a case of acute intestinal stoppage due to Meckel's diverticulum. After some notices about embryogenesis, pathological anatomy and symptomatology of Meckel's diverticula, they point out the difficulty to reach the diagnosis of such disease, which almost always is only done subsequent to the appearance of complications, such as: intestinal stoppage, inflammation, ulceration, perforation, neoplasms, bleeding. In fact, the diagnosis of Meckel's diverticulum is exceptionally preoperative and difficult on the basis of the symptomatology only, for which the disease can be responsible, whereas it can be more easily placed thanks to the contribution of instrumental methods, such as: barium meal, opaque enema, scintigraphy with 99mNa pertechnetate, selective arteriography of upper mesenterial artery. The diagnosis is more frequently interoperative, in course of explorative laparotomy or performed for other indications. Then the Authors state their orientation about the treatment, which is surgical in all the complex cases of Meckel's diverticulum, with a mention of the different operative techniques, and, as a conclusion, confirm the necessity for the systematic research of the asymptomatic diverticulum, the removal of which represents the only prophylactic measure against a permanent possibility and dreadful complicative evolution of same.

[The immunohistochemical demonstration of intracytoplasmic estradiol in colorectal neoplasms]. / Evidenziazione immunoistochimica dell'estradiolo intracitoplasmatico nelle neoplasie del colon-retto.

Intracytoplasmic estradiol content was studied retrospectively using immunohistochemical procedures in tissue samples from subjects suffering from colorectal cancer. The results obtained reveal the presence of intracytoplasmic estradiol in cancer tissue. In precancerous lesions this presence is rarer and inconstant. Estradiol was not detected in the healthy tissue examined. These data suggest that such tumours may depend to some degree on endocrine factors.

[Clinical considerations of jejunal carcinoma]. / Considerazioni cliniche sul carcinoma del digiuno.

The carcinoma of the jejunum represents 3-6.5% of gastric intestinal tumors and 33-50% of small intestine carcinomas. The observation of a case of jejunum carcinoma has offered the authors the idea for a critical revision on the subject. After an examination on the diagnostic, anatomopathological, clinical and therapeutic problems, the authors underline the importance of the precocious diagnosis of neoplasia; in fact the jejunum carcinoma is characterized by a hidden and aspecific symptomatology and by dangerous evolution; besides the site is difficult for an organic study with the common methods of investigation. Therefore, in all patients in whom the suspicion of a jejunum pathology exists, it is indispensable to carry out a precise diagnostic iter which is based on radiological endoscopic and tomographic investigation: in fact the small intestine and the jejunum in particular are intestinal tracts that are explored with difficult and therefore at times only an accurate effecting of the radiological study can permit a precocious diagnosis the only valid supposition for the carrying out of a truly radical surgical therapy and for the acquiring of a batter prognosis.