Pediatric Panoramic Radiography: Techniques, Artifacts, and Interpretation.

Panoramic radiography, particularly in the pediatric population, is rarely addressed in the radiology literature. The authors provide an in-depth discussion of how these images are acquired, what artifacts can be visualized, and how to mitigate these artifacts. Dental anatomy, as well as relevant osseous and soft-tissue anatomy visible on a panoramic image, are reviewed. The appearance of the normal pediatric panoramic radiograph, with an emphasis on the dental follicle, is discussed, as well as how to differentiate this normal structure from underlying pathologic conditions. The most commonly encountered pathologic conditions of carious disease and trauma are emphasized. A systematic approach to diagnosing mass lesions and their appropriate work-up, including multimodality imaging examples of relevant pathologic conditions, is also provided. Finally, congenital anomalies, including some of the more commonly encountered dysplasias, are reviewed. The authors provide a concise review of the relevant information needed to confidently interpret a pediatric panoramic radiograph. The online slide presentation from the RSNA Annual Meeting is available for this article. ©RSNA, 2021.

The Current and Future Roles of Precision Oncology in Advanced Breast Cancer.

Breast cancer is a common but heterogeneous disease characterized by several biologic features, including tumor grade, hormone receptor status, human epidermal growth factor receptor 2 status, and gene expression assays. These biologic and genomic features drive treatment decisions. In the advanced disease setting, inter- and intrapatient tumor heterogeneity is increasingly recognized as a challenge for optimizing treatment. Recent evidence and the recent approval of novel radiopharmaceuticals have increased recognition and acceptance of the potential of molecular imaging as a biomarker to impact and guide management decisions for advanced breast cancer.

Late Subacute Cerebral Hematoma Mimicking a Metastasis on PSMA PET/CT.

ABSTRACT: A 64-year-old man with history of prostate cancer was found to have rising prostate-specific antigen after radical prostatectomy. 18 F-DCFPyL PET/CT demonstrated a prostate-specific membrane antigen-avid brain lesion in the left frontal lobe and no other findings to account for rising prostate-specific antigen. Brain MRI demonstrated a small intraparenchymal hematoma with late subacute features in this location. The patient reported a seizure 3 weeks before but was otherwise asymptomatic, and neurologic examination was normal. Follow-up MRI demonstrated gradual decrease in size of the hematoma without treatment.

Post-operative imaging surveillance of breast cancer patients status post lumpectomy with BioZorb implant placement.

The evolving nature of newer surgical techniques and devices adds to the challenge of interpreting breast imaging in the post lumpectomy setting. The BioZorb surgical marker placed at lumpectomy sites for post-operative radiation targeting has its own distinct imaging appearance on each modality. Determining the expected follow-up imaging findings unique to this relatively new device is an ongoing endeavor with minimal literature on this topic. The following series of cases of post BioZorb breast surveillance are one of the first reported in the literature to provide examples of developing asymmetries and new or enlarging masses adjacent to the BioZorb site along with the final pathologic diagnosis for each case. Pathology findings range from fat necrosis and foreign body reaction to recurrent disease.