Detalles de la búsqueda
1.
Immunogenicity and Safety of a Purified Vero Rabies Vaccine - Serum Free, Compared With Two Licensed Vaccines, in a Simulated Rabies Post-Exposure Regimen in Healthy Adults in France: A Randomized Controlled Phase III Trial.
Clin Infect Dis
; 2024 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38478634
2.
Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 µg auto-injector in healthy volunteers.
Br J Clin Pharmacol
; 89(3): 1012-1019, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36136762
3.
A pharmacokinetic drug-drug interaction study between selexipag and midazolam, a CYP3A4 substrate, in healthy male subjects.
Eur J Clin Pharmacol
; 73(9): 1121-1128, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28639119
4.
Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Int J Clin Pract
; 71(9)2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28869722
5.
Changes in Activated Thrombin-Activatable Fibrinolysis Inhibitor Levels Following Thrombolytic Therapy in Ischemic Stroke Patients Correlate with Clinical Outcome.
Cerebrovasc Dis
; 42(5-6): 404-414, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27387478
6.
First-in-humans study of the safety, tolerability, and pharmacokinetics of ACT-451840, a new chemical entity with antimalarial activity.
Antimicrob Agents Chemother
; 59(2): 935-42, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25421475
7.
Digestive Symptoms in Healthy People and Subjects With Irritable Bowel Syndrome: Validation of Symptom Frequency Questionnaire.
J Clin Gastroenterol
; 49(7): e64-70, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25014236
8.
Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial.
J Transl Med
; 12: 38, 2014 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24507657
9.
Evaluation of the effects of therapeutic and supratherapeutic doses of agomelatine on the QT/QTc interval: a phase I, randomized, double-blind, placebo-controlled and positive-controlled, crossover thorough QT/QTc study conducted in healthy volunteers.
J Cardiovasc Pharmacol
; 64(5): 440-51, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24977347
10.
Effect on blood lipids of two daily servings of Camembert cheese. An intervention trial in mildly hypercholesterolemic subjects.
Int J Food Sci Nutr
; 65(8): 1013-8, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25095811
11.
Relative bioavailability of a newly developed pediatric formulation of bosentan vs. the adult formulation.
Int J Clin Pharmacol Ther
; 51(6): 529-36, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23611572
12.
Determination of the Optimal Single Dose Treatment for Acoziborole, a Novel Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Study.
Clin Pharmacokinet
; 62(3): 481-491, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36763327
13.
Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials.
Am J Clin Nutr
; 116(6): 1580-1594, 2022 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-36149331
14.
Absence of psychostimulant effects of a supratherapeutic dose of tianeptine: a placebo-controlled study versus methylphenidate in young healthy volunteers.
J Clin Psychopharmacol
; 31(4): 441-8, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21694627
15.
A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies: some points to consider from the French Club Phase I working group.
Br J Clin Pharmacol
; 70(5): 736-48, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21039768
16.
Similar immunogenicity of the A/H1N1 2009 pandemic influenza strain when used as a monovalent or a trivalent vaccine.
Hum Vaccin
; 6(10): 823-8, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20935517
17.
Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A.
Br J Clin Pharmacol
; 68(6): 928-35, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20002088
18.
Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial.
Nutr J
; 8: 9, 2009 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-19196472
19.
The New First-in-Human EMA Guideline: Disruptive or Constructive? Outcomes From the First EUFEMED Discussion Forum.
Front Pharmacol
; 10: 398, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31068811
20.
Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial.
Gut Microbes
; 9(3): 236-251, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29227175