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1.
J Appl Clin Med Phys ; 17(2): 573-582, 2016 03 08.
Artículo en Inglés | MEDLINE | ID: mdl-27074469

RESUMEN

Over the last two decades, there has been a concerted effort in North America to organize medical physicists' clinical training programs along more structured and formal lines. This effort has been prompted by the Commission on Accreditation of Medical Physics Education Programs (CAMPEP) which has now accredited about 90 residency programs. Initially the accreditation focused on standardized and higher quality clinical physics training; the development of rounded professionals who can function at a high level in a multidisciplinary environment was recognized as a priority of a radiation oncology physics residency only lately. In this report, we identify and discuss the implementation of, and the essential components of, a radiation oncology physics residency designed to produce knowledgeable and effective clinical physicists for today's safety-conscious and collaborative work environment. Our approach is that of inverse planning, by now familiar to all radiation oncology physicists, in which objectives and constraints are identified prior to the design of the program. Our inverse planning objectives not only include those associated with traditional residencies (i.e., clinical physics knowledge and critical clinical skills), but also encompass those other attributes essential for success in a modern radiation therapy clinic. These attributes include formal training in management skills and leadership, teaching and communication skills, and knowledge of error management techniques and patient safety. The constraints in our optimization exercise are associated with the limited duration of a residency and the training resources available. Without compromising the knowledge and skills needed for clinical tasks, we have successfully applied the model to the University of Calgary's two-year residency program. The program requires 3840 hours of overall commitment from the trainee, of which 7%-10% is spent in obtaining formal training in nontechnical "soft skills".


Asunto(s)
Competencia Clínica , Física Sanitaria/normas , Internado y Residencia , Desarrollo de Programa , Oncología por Radiación/normas , Acreditación , Educación Médica , Física Sanitaria/educación , Humanos , Modelos Teóricos , Oncología por Radiación/educación , Recursos Humanos
2.
Acta Oncol ; 53(3): 324-9, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23957683

RESUMEN

PURPOSE: To evaluate the clinical impact of using the deterministic dose calculation algorithm, Acuros XB, for early stage lung cancer patients undergoing stereotactic body radiotherapy (SBRT). MATERIAL AND METHODS: Seventy-seven stage I non-small cell lung cancer patients who underwent lung SBRT from 2008 to 2012 at our center were included in this study. All treatment plans originally calculated by the anisotropic analytical algorithm (AAA) were recalculated using the AAA and Acuros XB algorithms with identical monitor units and beam arrangements. The dose, dose distribution, conformality number (CN) and heterogeneity index (HI) of the target were determined for each plan. A paired matched t-test was used to evaluate the difference between the mean dose, the dose distribution, and the CN and HI for the target. The importance of tumor (volume, location), patient (pulmonary functional, body mass index) and treatment (number of SBRT beams) on the dose distributions obtained from the two algorithms was statistically determined using linear regression analyses. RESULTS: The mean target dose was same for both algorithms. Compared to AAA, a small and significant difference in dose distribution in the target was found for the Acuros XB algorithm, resulting in lower conformity (-2.1%, p < 0.0001) and higher heterogeneity (p < 0.0001) of dose. Single logistic regression identified pulmonary function, number of beams and target location as being correlated with the difference of CN between the two calculations. Multivariate analysis indicated that the patient's pulmonary function (p = 0.0296) was the only predictor for the difference in conformality between the two dose calculation algorithms. CONCLUSIONS: In lung SBRT, the patient's pulmonary function is responsible for the difference in target dose distribution between the Acuros XB and AAA algorithms. The Acuros XB algorithm could be used to advantage in patients with compromised pulmonary function based on its accurate modeling of lung tissue in comparison to AAA.


Asunto(s)
Carcinoma de Pulmón de Células no Pequeñas/cirugía , Neoplasias Pulmonares/cirugía , Radiocirugia/métodos , Planificación de la Radioterapia Asistida por Computador/métodos , Algoritmos , Índice de Masa Corporal , Humanos , Análisis Multivariante , Dosificación Radioterapéutica
3.
J Appl Clin Med Phys ; 13(3): 3767, 2012 May 10.
Artículo en Inglés | MEDLINE | ID: mdl-22584177

RESUMEN

We have previously demonstrated the use of Eclipse fluence optimization to define aperture sizes for a novel aperture modulated translating bed total body irradiation (TBI) technique. The purposes of the present study were to identify, characterize, and correct for sources of error inherent in our previous fluence optimization technique, and to develop a clinically viable fluence optimization module for the translating bed TBI technique. Aperture modulated TBI is delivered by translating the patient at constant speed on a custom bed under a modulated radiation beam. The patient is then turned from supine to prone and the process repeated, resulting in an AP-PA treatment. Radiological depths were calculated along divergent ray lines through individual CT slices of a RANDO phantom. Beam apertures, defined using a dynamic multileaf collimator (DMLC), were generated using calculated radiological depths and calibration factors that relate fluence to aperture size in a dynamic environment. These apertures were defined every 9 mm along the phantom superior-inferior axis. The calculated beam apertures were further modified to account for scatter within the patient. For dose calculation purposes the individual MLC files were imported into Eclipse. For treatment delivery, dynamic MLC files for both AP and PA beams were generated and delivered dynamically. Dose homogeneity in the head and neck region of the RANDO phantom was within ± 4% of the prescribed dose with this novel technique compared to -5% to +7% with our previous aperture modulated technique based on Eclipse fluence optimization. Fluence optimization and beam aperture calculation using the new technique offers a ten-fold reduction in planning time and significantly reduces the likelihood of user error during the planning process. In conclusion, a clinically viable aperture modulated translating bed TBI technique that employs dynamically shaped MLC-defined beam apertures based on radiological depth calculations, has been developed.


Asunto(s)
Neoplasias de Cabeza y Cuello/radioterapia , Irradiación Corporal Total/métodos , Neoplasias de Cabeza y Cuello/diagnóstico por imagen , Humanos , Fantasmas de Imagen , Dosificación Radioterapéutica , Planificación de la Radioterapia Asistida por Computador/métodos , Radioterapia Conformacional/métodos , Radioterapia de Intensidad Modulada/métodos , Tomografía Computarizada Espiral
4.
Med Phys ; 38(2): 932-41, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21452729

RESUMEN

PURPOSE: Total body irradiation (TBI) techniques aim to deliver a uniform radiation dose to a patient with an irregular body contour and a heterogeneous density distribution to within +/-10% of the prescribed dose. In the current article, the authors present a novel, aperture modulated, translating bed TBI (AMTBI) technique that produces a high degree of dose uniformity throughout the entire patient. METHODS: The radiation beam is dynamically shaped in two dimensions using a multileaf collimator (MLC). The irregular surface compensation algorithm in the Eclipse treatment planning system is used for fluence optimization, which is performed based on penetration depth and internal inhomogeneities. Two optimal fluence maps (AP and PA) are generated and beam apertures are created to deliver these optimal fluences. During treatment, the patient/phantom is translated on a motorized bed close to the floor (source to bed distance: 204.5 cm) under a stationary radiation beam with 0 degree gantry angle. The bed motion and dynamic beam apertures are synchronized. RESULTS: The AMTBI technique produces a more homogeneous dose distribution than fixed open beam translating bed TBI. In phantom studies, the dose deviation along the midline is reduced from 10% to less than 5% of the prescribed dose in the longitudinal direction. Dose to the lung is reduced by more than 15% compared to the unshielded fixed open beam technique. At the lateral body edges, the dose received from the open beam technique was 20% higher than that prescribed at umbilicus midplane. With AMTBI the dose deviation in this same region is reduced to less than 3% of the prescribed dose. Validation of the technique was performed using thermoluminescent dosimeters in a Rando phantom. Agreement between calculation and measurement was better than 3% in all cases. CONCLUSIONS: A novel, translating bed, aperture modulated TBI technique that employs dynamically shaped MLC defined beams is shown to improve dose uniformity in three dimensions. In comparison with the fixed open beam TBI technique, homogeneity of dose distribution is greatly improved.


Asunto(s)
Movimiento (Física) , Posicionamiento del Paciente/métodos , Irradiación Corporal Total/métodos , Humanos , Fantasmas de Imagen , Dosis de Radiación , Planificación de la Radioterapia Asistida por Computador , Dosimetría Termoluminiscente
5.
J Appl Clin Med Phys ; 12(2): 3449, 2011 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-21587193

RESUMEN

A database of clinically approved stereotactic radiosurgery treatment plans was created. One hundred and seventy targets in the database were then retrospectively evaluated using conformity indices suggested by RTOG, SALT-Lomax and Paddick. Relationships between the three alternative conformity indices were determined. The Paddick index combines the information provided by the RTOG and SALT-Lomax indices into a single index. The variation in the geometric overlap ratio, which is related to the SALT-Lomax index, was found to be not clinically relevant for our cohort of patients, and thus the Paddick and RTOG indices can be directly related. It was found that access to a dose volume histogram or dose distribution for a treatment plan renders the RTOG conformity index sufficient for plan quality evaluation.


Asunto(s)
Neoplasias Encefálicas/radioterapia , Radiocirugia/métodos , Algoritmos , Neoplasias Encefálicas/secundario , Bases de Datos Factuales , Femenino , Humanos , Masculino , Oncología Médica/métodos , Modelos Teóricos , Metástasis de la Neoplasia , Neoplasias/patología , Neoplasias/radioterapia , Dosificación Radioterapéutica , Radioterapia Conformacional/métodos , Reproducibilidad de los Resultados , Estudios Retrospectivos
6.
Med Phys ; 37(7): 3862-7, 2010 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-20831094

RESUMEN

PURPOSE: Patient specific IMRT QC is performed routinely in many clinics as a safeguard against errors and inaccuracies which may be introduced during the complex planning, data transfer, and delivery phases of this type of treatment. The purpose of this work is to evaluate the feasibility of detecting systematic errors in MLC leaf bank position with patient specific checks. METHODS: 9 head and neck (H&N) and 14 prostate IMRT beams were delivered using MLC files containing systematic offsets (+/- 1 mm in two banks, +/- 0.5 mm in two banks, and 1 mm in one bank of leaves). The beams were measured using both MAPCHECK (Sun Nuclear Corp., Melbourne, FL) and the aS1000 electronic portal imaging device (Varian Medical Systems, Palo Alto, CA). Comparisons with calculated fields, without offsets, were made using commonly adopted criteria including absolute dose (AD) difference, relative dose difference, distance to agreement (DTA), and the gamma index. RESULTS: The criteria most sensitive to systematic leaf bank offsets were the 3% AD, 3 mm DTA for MAPCHECK and the gamma index with 2% AD and 2 mm DTA for the EPID. The criterion based on the relative dose measurements was the least sensitive to MLC offsets. More highly modulated fields, i.e., H&N, showed greater changes in the percentage of passing points due to systematic MLC inaccuracy than prostate fields. CONCLUSIONS: None of the techniques or criteria tested is sufficiently sensitive, with the population of IMRT fields, to detect a systematic MLC offset at a clinically significant level on an individual field. Patient specific QC cannot, therefore, substitute for routine QC of the MLC itself.


Asunto(s)
Artefactos , Medicina de Precisión , Radioterapia de Intensidad Modulada/normas , Estudios de Factibilidad , Neoplasias de Cabeza y Cuello/radioterapia , Humanos , Masculino , Neoplasias de la Próstata/radioterapia , Control de Calidad , Dosificación Radioterapéutica , Radioterapia de Intensidad Modulada/métodos
7.
Med Phys ; 37(8): 4495-500, 2010 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-20879608

RESUMEN

The AAPM Professional Council approved the formation of a task group in 2007, whose purpose is to develop recommendations for an ethics curriculum for medical physics graduate and residency programs. Existing program's ethics curricula range in scope and content considerably. It is desirable to have a more uniform baseline curriculum for all programs. Recommended subjects areas, suggested ethics references, and a sample curriculum are included. This report recommends a reasonable ethics course time to be 15-30 h while allowing each program the flexibility to design their course.


Asunto(s)
Curriculum/normas , Educación de Postgrado en Medicina/normas , Educación Médica/normas , Física Sanitaria/educación , Física Sanitaria/normas , Internado y Residencia/normas , Estados Unidos
8.
J Appl Clin Med Phys ; 11(3): 3213, 2010 Jun 08.
Artículo en Inglés | MEDLINE | ID: mdl-20717088

RESUMEN

The accuracy of dose calculations at extended SSD is of significant importance in the dosimetric planning of total body irradiation (TBI). In a first step toward the implementation of electronic, multi-leaf collimator compensation for dose inhomogeneities and surface contour in TBI, we have evaluated the ability of the Eclipse AAA to accurately predict dose distributions in water at extended SSD. For this purpose, we use the Eclipse AAA algorithm, commissioned with machine-specific beam data for a 6 MV photon beam, at standard SSD (100 cm). The model was then used for dose distribution calculations at extended SSD (179.5 cm). Two sets of measurements were acquired for a 6 MV beam (from a Varian linear accelerator) in a water tank at extended SSD: i) open beam for 5 x 5, 10 x 10, 20 x 20 and 40 x 40 cm2 field sizes (defined at 179.5 cm SSD), and ii) identical field sizes but with a 1.3 cm thick acrylic spoiler placed 10 cm above the water surface. Dose profiles were acquired at 5 cm, 10 cm and 20 cm depths. Dose distributions for the two setups were calculated using the AAA algorithm in Eclipse. Confidence limits for comparisons between measured and calculated absolute depth dose curves and normalized dose profiles were determined as suggested by Venselaar et al. The confidence limits were within 2% and 2 mm for both setups. Extended SSD calculations were also performed using Eclipse AAA, commissioned with Varian Golden beam data at standard SSD. No significant difference between the custom commissioned and Golden Eclipse AAA was observed. In conclusion, Eclipse AAA commissioned at standard SSD can be used to accurately predict dose distributions in water at extended SSD for 6 MV open beams.


Asunto(s)
Algoritmos , Planificación de la Radioterapia Asistida por Computador , Irradiación Corporal Total , Simulación por Computador , Humanos , Aceleradores de Partículas , Fantasmas de Imagen , Fotones , Radiometría , Dosificación Radioterapéutica , Agua
9.
Med Phys ; 36(7): 3304-9, 2009 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-19673226

RESUMEN

The objective determination of performance standards for radiation therapy equipment requires, ideally, establishing the quantitative relationship between performance deviations and clinical outcome or some acceptable surrogate. In this simulation study the authors analyzed the dosimetric impact of random (leaf by leaf) and systematic (entire leaf bank) errors in the position of the MLC leaves on seven clinical prostate and seven clinical head and neck IMRT plans delivered using a dynamic MLC. In-house software was developed to incorporate normally distributed errors of up to +/- 2 mm in individual leaf position or systematic errors (+/- 1 and +/- 0.5 mm in all leaves of both leaf banks or +1 mm in one bank only) into the 14 plans, thus simulating treatment delivery using a suboptimally performing MLC. The dosimetric consequences of suboptimal MLC performance were quantified using the equivalent uniform doses (EUDs) of the clinical target volumes and important organs at risk (OARs). The deviation of the EUDs of the selected structures as the performance of the MLC deteriorated was used as the objective surrogate of clinical outcome. Random errors of 2 mm resulted in negligible changes for all structures of interest in both sites. In contrast, systematic errors can lead to potentially significant dosimetric changes that may compromise clinical outcome. If a 2% change in EUD of the target and 2 Gy for the OARs were adopted as acceptable levels of deviation in dose due to MLC effects alone, then systematic errors in leaf position will need to be limited to 0.3 mm. This study provides guidance, based on a dosimetric surrogate of clinical outcome, for the development of one component, leaf position accuracy of performance standards for multileaf collimators.


Asunto(s)
Simulación por Computador , Planificación de la Radioterapia Asistida por Computador , Radioterapia de Intensidad Modulada/métodos , Tronco Encefálico/efectos de la radiación , Neoplasias de Cabeza y Cuello/radioterapia , Humanos , Laringe/efectos de la radiación , Masculino , Glándula Parótida/efectos de la radiación , Neoplasias de la Próstata/radioterapia , Radiometría , Dosificación Radioterapéutica , Recto/efectos de la radiación , Riesgo , Programas Informáticos , Médula Espinal/efectos de la radiación , Vejiga Urinaria/efectos de la radiación
11.
Int J Radiat Oncol Biol Phys ; 71(1 Suppl): S200-3, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18406929

RESUMEN

Recent publications in both the scientific and the popular press have highlighted the risks to which patients expose themselves when entering a healthcare system. Patient safety issues are forcing us to, not only acknowledge that incidents do occur, but also actively develop the means for assessing and managing the risks of such incidents. To do this, we ideally need to know the probability of an incident's occurrence, the consequences or severity for the patient should it occur, and the basic causes of the incident. A structured approach to the description of failure modes is helpful in terms of communication, avoidance of ambiguity, and, ultimately, decision making for resource allocation. In this report, several classification schemes or taxonomies for use in risk assessment and management are discussed. In particular, a recently developed approach that reflects the activity domains through which the patient passes and that can be used as a basis for quantifying incident severity is described. The estimation of incident severity, which is based on the concept of the equivalent uniform dose, is presented in some detail. We conclude with a brief discussion on the use of a defined basic-causes table and how adding such a table to the reports of incidents can facilitate the allocation of resources.


Asunto(s)
Algoritmos , Errores Médicos/clasificación , Radioterapia/efectos adversos , Gestión de Riesgos/métodos , Braquiterapia/efectos adversos , Bases de Datos Factuales , Toma de Decisiones , Humanos , Errores Médicos/prevención & control , Asignación de Recursos , Administración de la Seguridad
12.
Int J Radiat Oncol Biol Phys ; 71(1 Suppl): S2-12, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18406928

RESUMEN

This report summarizes the consensus findings and recommendations emerging from 2007 Symposium, "Quality Assurance of Radiation Therapy: Challenges of Advanced Technology." The Symposium was held in Dallas February 20-22, 2007. The 3-day program, which was sponsored jointly by the American Society for Therapeutic Radiology and Oncology (ASTRO), American Association of Physicists in Medicine (AAPM), and National Cancer Institute (NCI), included >40 invited speakers from the radiation oncology and industrial engineering/human factor communities and attracted nearly 350 attendees, mostly medical physicists. A summary of the major findings follows. The current process of developing consensus recommendations for prescriptive quality assurance (QA) tests remains valid for many of the devices and software systems used in modern radiotherapy (RT), although for some technologies, QA guidance is incomplete or out of date. The current approach to QA does not seem feasible for image-based planning, image-guided therapies, or computer-controlled therapy. In these areas, additional scientific investigation and innovative approaches are needed to manage risk and mitigate errors, including a better balance between mitigating the risk of catastrophic error and maintaining treatment quality, complimenting the current device-centered QA perspective by a more process-centered approach, and broadening community participation in QA guidance formulation and implementation. Industrial engineers and human factor experts can make significant contributions toward advancing a broader, more process-oriented, risk-based formulation of RT QA. Healthcare administrators need to appropriately increase personnel and ancillary equipment resources, as well as capital resources, when new advanced technology RT modalities are implemented. The pace of formalizing clinical physics training must rapidly increase to provide an adequately trained physics workforce for advanced technology RT. The specific recommendations of the Symposium included the following. First, the AAPM, in cooperation with other advisory bodies, should undertake a systematic program to update conventional QA guidance using available risk-assessment methods. Second, the AAPM advanced technology RT Task Groups should better balance clinical process vs. device operation aspects--encouraging greater levels of multidisciplinary participation such as industrial engineering consultants and use-risk assessment and process-flow techniques. Third, ASTRO should form a multidisciplinary subcommittee, consisting of physician, physicist, vendor, and industrial engineering representatives, to better address modern RT quality management and QA needs. Finally, government and private entities committed to improved healthcare quality and safety should support research directed toward addressing QA problems in image-guided therapies.


Asunto(s)
Braquiterapia/normas , Oncología por Radiación/normas , Planificación de la Radioterapia Asistida por Computador/normas , Radioterapia de Intensidad Modulada/normas , Control de Calidad , Tecnología Radiológica/normas
13.
Int J Radiat Oncol Biol Phys ; 71(1 Suppl): S170-3, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18406920

RESUMEN

The increasing complexity of modern radiation therapy planning and delivery techniques challenges traditional prescriptive quality control and quality assurance programs that ensure safety and reliability of treatment planning and delivery systems under all clinical scenarios. Until now quality management (QM) guidelines published by concerned organizations (e.g., American Association of Physicists in Medicine [AAPM], European Society for Therapeutic Radiology and Oncology [ESTRO], International Atomic Energy Agency [IAEA]) have focused on monitoring functional performance of radiotherapy equipment by measurable parameters, with tolerances set at strict but achievable values. In the modern environment, however, the number and sophistication of possible tests and measurements have increased dramatically. There is a need to prioritize QM activities in a way that will strike a balance between being reasonably achievable and optimally beneficial to patients. A systematic understanding of possible errors over the course of a radiation therapy treatment and the potential clinical impact of each is needed to direct limited resources in such a way to produce maximal benefit to the quality of patient care. Task Group 100 of the AAPM has taken a broad view of these issues and is developing a framework for designing QM activities, and hence allocating resources, based on estimates of clinical outcome, risk assessment, and failure modes. The report will provide guidelines on risk assessment approaches with emphasis on failure mode and effect analysis (FMEA) and an achievable QM program based on risk analysis. Examples of FMEA to intensity-modulated radiation therapy and high-dose-rate brachytherapy are presented. Recommendations on how to apply this new approach to individual clinics and further research and development will also be discussed.


Asunto(s)
Algoritmos , Benchmarking/métodos , Guías de Práctica Clínica como Asunto/normas , Control de Calidad , Radioterapia/normas , Benchmarking/normas , Humanos , Errores Médicos , Radioterapia de Intensidad Modulada/normas , Asignación de Recursos , Medición de Riesgo/métodos , Análisis de Sistemas
14.
Radiother Oncol ; 86(2): 217-23, 2008 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-18237802

RESUMEN

BACKGROUND AND PURPOSE: The rising cost of health care is of universal concern. If the cost effectiveness of conventional and novel radiotherapeutic strategies is to be established we need to have confidence in our estimates of both cost and effectiveness. The purpose of this study is to explore the degree of consistency of recently published cost estimates for radiation therapy. METHODS AND MATERIALS: Eleven publications form the basis of this analysis. From each study we have estimated the cost of a 21 fraction course (when possible) of radiation therapy. The costs have been decomposed into the three inputs: process, clinical infrastructure and supporting infrastructure. We have also investigated the time course of radiation therapy costs over the last two decades. RESULTS: From the latest four studies we conclude that the cost of a 21 fraction course of radiation therapy is 3239 euro+/-566 euro. The percentages of this total spent on process, clinical infrastructure and supporting infrastructure over the last 15 years are 54, 29 and 17, respectively. The real increase in the cost of radiotherapy over the last 15 years is estimated to be approximately 5.5%. CONCLUSION: Cost estimates for radiation therapy appear to be converging. However, we will need far more sophisticated analyses in the future if we are to establish the cost effectiveness of the newer treatment strategies currently under active clinical investigation.


Asunto(s)
Neoplasias/radioterapia , Radioterapia/economía , Análisis Costo-Beneficio , Fraccionamiento de la Dosis de Radiación , Costos de la Atención en Salud , Humanos
15.
Med Phys ; 35(12): 5303-11, 2008 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-19175089

RESUMEN

The authors describe a detailed evaluation of the capabilities of imaging and image registration systems available with Varian linear accelerators for image guided radiation therapy (IGRT). Specifically, they present modulation transfer function curves for megavoltage planar, kilovoltage (kV) planar, and cone beam computed tomography imaging systems and compare these with conventional computed tomography. While kV planar imaging displayed the highest spatial resolution, all IGRT imaging techniques were assessed as adequate for their intended purpose. They have also characterized the image registration software available for use in conjunction with these imaging systems through a comprehensive phantom study involving translations in three orthogonal directions. All combinations of imaging systems and image registration software were found to be accurate, although the planar kV imaging system with automatic registration was generally superior, with both accuracy and precision of the order of 1 mm, under the conditions tested. Based on their phantom study, the attainable accuracy for rigid body translations using any of the features available with Varian equipment will more likely be limited by the resolution of the couch readouts than by inherent limitations in the imaging systems and image registration software. Overall, the accuracy and precision of currently available IGRT technology exceed published experience with the accuracy and precision of contouring for planning.


Asunto(s)
Radiometría/métodos , Radioterapia/métodos , Automatización , Procesamiento Automatizado de Datos , Diseño de Equipo , Humanos , Procesamiento de Imagen Asistido por Computador , Modelos Estadísticos , Aceleradores de Partículas , Fantasmas de Imagen , Reproducibilidad de los Resultados , Procesamiento de Señales Asistido por Computador , Programas Informáticos , Tomografía Computarizada por Rayos X
16.
Med Phys ; 35(6): 2513-8, 2008 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-18649484

RESUMEN

Radiation therapy, along with other branches of medicine, is moving towards a firmer basis in evidence to optimally utilize resources. As new treatment technology and strategies place greater demands on quality assurance resources, the need to objectively evaluate equipment and process performance standards from the perspective of predicted clinical impact becomes more urgent. This study evaluates the appropriateness of recommended quality control tolerance and action levels for linear accelerators based on the calculated dosimetric impact of suboptimal equipment performance. A method is described to quantify the dosimetric changes, as reflected by the changes in the outcome surrogate, equivalent uniform dose (EUD), of machine performance deviations from the optimal, specifically in the range of tolerance and action levels promulgated by the Canadian Association of Provincial Cancer Agencies (CAPCA). Linear accelerator performance deviations were simulated for the treatment of prostate, breast, lung, and brain using 3D conformal techniques, and the impact evaluated in terms of the changes in the EUD of the target volumes and two principal organs at risk (OARs) per site. The eight key performance characteristics examined are: Output constancy, beam flatness, gantry angle, collimator angle, field size indicator, laser alignment (three directions) and, by inference, the optical distance indicator. Currently accepted CAPCA tolerance levels for these eight performance characteristics are shown to maintain average EUD deviations to within 2% for the targets and 2 Gy for the OARs. However, within the 2% or 2 Gy range, the recommended tolerance levels are found to have markedly different effects on the EUDs of the structures of interest.


Asunto(s)
Aceleradores de Partículas/normas , Radioterapia/métodos , Encéfalo/efectos de la radiación , Mama/efectos de la radiación , Humanos , Pulmón/efectos de la radiación , Masculino , Próstata/efectos de la radiación , Control de Calidad , Radiometría , Dosificación Radioterapéutica , Planificación de la Radioterapia Asistida por Computador , Radioterapia Conformacional
17.
Radiother Oncol ; 126(2): 183-190, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-28988660

RESUMEN

BACKGROUND AND PURPOSE: The IAEA has developed a methodology for comprehensive quality audits of radiotherapy practices called Quality Assurance Team for Radiation Oncology (QUATRO). This study explores the factors that impacted quality of care among QUATRO audited centres in the IAEA Europe Region. MATERIALS AND METHODS: The 31 QUATRO reports collected over 10years include extensive data describing the quality of radiotherapy at the audited centres. A coding key was developed to aggregate and review these data in terms of recommendations for improvement and positive findings (commendations). RESULTS: Overall 759 recommendations and 600 commendations were given. Eight centres recognized as centres of competence differed from other centres mostly because they operated complete quality management systems and were adequately staffed. Other centres had excessive staff workloads and many gaps in the process of care. Insufficient equipment levels were prevalent. Patient centredness, communication, dosimetry, quality control and radiation protection were frequently commended by QUATRO. CONCLUSIONS: This analysis points to barriers to quality care such as insufficient staffing, education/training, equipment and lack of quality management. It highlights the correlation between the human resources availability and quality of care. It has also identified common action items for enhancing quality of radiotherapy programmes in the Region.


Asunto(s)
Oncología por Radiación/métodos , Oncología por Radiación/normas , Europa (Continente) , Humanos , Agencias Internacionales , Auditoría Médica , Garantía de la Calidad de Atención de Salud , Control de Calidad
18.
Int J Radiat Oncol Biol Phys ; 67(1): 71-7, 2007 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-16997500

RESUMEN

PURPOSE: The aim of this study was to demonstrate, based on clinical postplan dose distributions, that technology can be used efficiently to eliminate the learning curve associated with permanent seed implant planning and delivery. METHODS AND MATERIALS: Dose distributions evaluated 30 days after the implant of the initial 22 consecutive patients treated with permanent seed implants at two institutions were studied. Institution 1 (I1) consisted of a new team, whereas institution 2 (I2) had performed more than 740 preplanned implantations over a 9-year period before the study. Both teams had adopted similar integrated systems based on three-dimensional (3D) transrectal ultrasonography, intraoperative dosimetry, and an automated seed delivery and needle retraction system (FIRST, Nucletron). Procedure time and dose volume histogram parameters such as D90, V100, V150, V200, and others were collected in the operating room and at 30 days postplan. RESULTS: The average target coverage from the intraoperative plan (V100) was 99.4% for I1 and 99.9% for I2. D90, V150, and V200 were 191.4 Gy (196.3 Gy), 75.3% (73.0%), and 37.5% (34.1%) for I1 (I2) respectively. None of these parameters shows a significant difference between institutions. The postplan D90 was 151.2 Gy for I1 and 167.3 Gy for I2, well above the 140 Gy from the Stock et al. analysis, taking into account differences at planning, results in a p value of 0.0676. The procedure time required on average 174.4 min for I1 and 89 min for I2. The time was found to decrease with the increasing number of patients. CONCLUSION: State-of-the-art technology enables a new brachytherapy team to obtain excellent postplan dose distributions, similar to those achieved by an experienced team with proven long-term clinical results. The cost for bypassing the usual dosimetry learning curve is time, with increasing team experience resulting in shorter treatment times.


Asunto(s)
Braquiterapia/métodos , Práctica Psicológica , Neoplasias de la Próstata/radioterapia , Tecnología Radiológica/normas , Braquiterapia/normas , Braquiterapia/estadística & datos numéricos , Competencia Clínica , Humanos , Imagenología Tridimensional , Masculino , Neoplasias de la Próstata/diagnóstico por imagen , Dosificación Radioterapéutica , Factores de Tiempo , Ultrasonografía
19.
Radiother Oncol ; 84(1): 64-6, 2007 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-17586076

RESUMEN

In allocating resources within a risk management program, ideally we would like to know both the probabilities and consequences of potential incidents. We simulate, on a treatment planning computer, several commonly reported incidents in radiation treatment and explore their consequences for the EUDs of targets and organs at risk.


Asunto(s)
Traumatismos por Radiación/diagnóstico , Planificación de la Radioterapia Asistida por Computador , Encéfalo/efectos de la radiación , Mama/efectos de la radiación , Fraccionamiento de la Dosis de Radiación , Femenino , Humanos , Pulmón/efectos de la radiación , Masculino , Modelos Biológicos , Próstata/efectos de la radiación , Radioterapia Conformacional , Medición de Riesgo
20.
Brachytherapy ; 6(4): 254-7, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17991622

RESUMEN

INTRODUCTION: In 2003, the Tom Baker Cancer Centre started a prostate brachytherapy program using Iodine-125 seeds, intraoperative treatment planning, and an automated remote afterloader, the seedSelectron. Over a 3-month period in 2004-2005, technologic changes were implemented with the intent of reducing the time spent in the operating room and improving ergonomics for the radiation oncologist/surgeon. New commercial software including inverse planning was installed, concurrent needle insertion and seed train building was implemented, and additional hardware (a slave monitor) was connected to the system. PURPOSE: To demonstrate that, with these enhancements, dosimetry is not compromised, whereas efficiency is significantly improved. METHODS: Interactive inverse planning was used to create the treatment plans in the operating room. Seed-spacer trains were built concurrently with each needle's insertion guided by rotating the ultrasound probe to the correct sagittal plane using the Needle Navigator feature. Needles were built, inserted, and delivered one needle at a time. Needle coordinate and insert positions were verified on the live ultrasound image displayed on both the slave monitor positioned above the patient's pelvis and the operator console. Dosimetry parameters (D(90) and V(100)), numbers of seeds, and OR times were compared for 20 patients before and 11 patients after the implementation of the concurrent insertion and build protocol combined with inverse planning and the slave monitor. RESULTS: Operating room (OR) times (probe in to probe out) were reduced by 33 min and the number of seeds per unit volume by 3% on an average. The majority of the decrease in time is due to the concurrent building and insertion of needles. Before and after the new technique, average postplan D(90) and V(100) values at 4 weeks after the implant were the same to within 4 Gy and 0.1%, respectively. The range (max-min) of D(90) decreased by 20% of the mean dose and the V(100) range decreased by 6% with the new technique. Adding the slave monitor improved quality assurance of the delivery process and ergonomics for physicians. CONCLUSIONS: The concurrent insertion and build protocol, together with inverse planning and the slave monitor, have decreased OR times with greater consistency in the delivered dose distribution.


Asunto(s)
Braquiterapia/métodos , Próstata/diagnóstico por imagen , Neoplasias de la Próstata/radioterapia , Planificación de la Radioterapia Asistida por Computador/métodos , Ergonomía , Humanos , Radioisótopos de Yodo , Masculino , Agujas , Quirófanos/organización & administración , Neoplasias de la Próstata/diagnóstico por imagen , Ultrasonografía
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