1.
Case Rep Oncol
; 15(3): 874-880, 2022.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36825101
RESUMEN
A diagnosis of acute myeloid leukemia involving the central nervous system (CNS) can be confirmed through cerebrospinal fluid (CSF) and serum flow cytometry. These two detection methods should demonstrate the same immunophenotype due to hematogenous dissemination. Here, we reported a 65-year-old male diagnosed with CNS leukemia with differing immunophenotypes between CSF and peripheral blood. This immunophenotypic shift may suggest leukemic migration within the blood-brain barrier. In addition, the case highlights the concept of leukemic heterogeneity and the importance of considering cancer heterogeneity when analyzing a tumor's genetic profile and selecting therapy for patients.
2.
Heart
; 110(7): 507-540, 2024 Mar 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38471725