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1.
Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture.
Regul Toxicol Pharmacol
; 115: 104697, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32590049
2.
Carcinogenicity risk assessment of romosozumab: A review of scientific weight-of-evidence and findings in a rat lifetime pharmacology study.
Regul Toxicol Pharmacol
; 81: 212-222, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27569204
3.
Inhibition of both sclerostin and DKK1 results in novel skull findings in the rat and non-human primate that is not observed with inhibition of sclerostin alone.
Bone
; 179: 116985, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38052372
4.
Pharmacokinetics and local tissue response to local instillation of vocacapsaicin, a novel capsaicin prodrug, in rat and rabbit osteotomy models.
J Orthop Res
; 40(10): 2281-2293, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35128722
5.
A 28-Day Toxicity Study of Tenofovir Alafenamide Hemifumarate by Subcutaneous Infusion in Rats and Dogs.
Microbiol Spectr
; 9(1): e0033921, 2021 09 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34190595
6.
Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody.
Bone Rep
; 8: 90-94, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29955626
7.
Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys.
J Bone Miner Res
; 32(4): 788-801, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27865001
8.
Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma.
Clin Sci (Lond)
; 110(6): 645-54, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16417466
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