Búsqueda | BVS CLAP/SMR-OPS/OMS

1.

Gut inflammation and adaptive immunity amplify acetaminophen toxicity in bowel and liver.

Alabbas, Saleh Y; Giri, Rabina; Oancea, Iulia; Davies, Julie; Schreibner, Veronika; Florin, Timothy H; Begun, Jakob.

J Gastroenterol Hepatol ; 38(4): 609-618, 2023 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-36598244

2.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Walker, Gareth J; Harrison, James W; Heap, Graham A; Voskuil, Michiel D; Andersen, Vibeke; Anderson, Carl A; Ananthakrishnan, Ashwin N; Barrett, Jeffrey C; Beaugerie, Laurent; Bewshea, Claire M; Cole, Andy T; Cummings, Fraser R; Daly, Mark J; Ellul, Pierre; Fedorak, Richard N; Festen, Eleonora A M; Florin, Timothy H; Gaya, Daniel R; Halfvarson, Jonas; Hart, Ailsa L; Heerasing, Neel M; Hendy, Peter; Irving, Peter M; Jones, Samuel E; Koskela, Jukka; Lindsay, James O; Mansfield, John C; McGovern, Dermot; Parkes, Miles; Pollok, Richard C G; Ramakrishnan, Subramaniam; Rampton, David S; Rivas, Manuel A; Russell, Richard K; Schultz, Michael; Sebastian, Shaji; Seksik, Philippe; Singh, Abhey; So, Kenji; Sokol, Harry; Subramaniam, Kavitha; Todd, Anthony; Annese, Vito; Weersma, Rinse K; Xavier, Ramnik; Ward, Rebecca; Weedon, Michael N; Goodhand, James R; Kennedy, Nicholas A; Ahmad, Tariq.

JAMA ; 321(8): 773-785, 2019 02 26.

Artículo en Inglés | MEDLINE | ID: mdl-30806694

3.

Therapeutic Drug Monitoring for IBD Children on Thioguanine.

Florin, Timothy H; Duley, John A.

J Pediatr Gastroenterol Nutr ; 77(3): e64-e65, 2023 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-37346029

4.

Serologic antibodies in relation to outcome in postoperative Crohn's disease.

Hamilton, Amy L; Kamm, Michael A; De Cruz, Peter; Wright, Emily K; Selvaraj, Fabiyola; Princen, Fred; Gorelik, Alexandra; Liew, Danny; Lawrance, Ian C; Andrews, Jane M; Bampton, Peter A; Sparrow, Miles P; Florin, Timothy H; Gibson, Peter R; Debinski, Henry; Gearry, Richard B; Macrae, Finlay A; Leong, Rupert W; Kronborg, Ian; Radford-Smith, Graham; Selby, Warwick; Bell, Sally J; Brown, Steven J; Connell, William R.

J Gastroenterol Hepatol ; 32(6): 1195-1203, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-27976801

5.

Crohn's disease management after intestinal resection: a randomised trial.

De Cruz, Peter; Kamm, Michael A; Hamilton, Amy L; Ritchie, Kathryn J; Krejany, Efrosinia O; Gorelik, Alexandra; Liew, Danny; Prideaux, Lani; Lawrance, Ian C; Andrews, Jane M; Bampton, Peter A; Gibson, Peter R; Sparrow, Miles; Leong, Rupert W; Florin, Timothy H; Gearry, Richard B; Radford-Smith, Graham; Macrae, Finlay A; Debinski, Henry; Selby, Warwick; Kronborg, Ian; Johnston, Michael J; Woods, Rodney; Elliott, P Ross; Bell, Sally J; Brown, Steven J; Connell, William R; Desmond, Paul V.

Lancet ; 385(9976): 1406-17, 2015 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-25542620

6.

Measurement of fecal calprotectin improves monitoring and detection of recurrence of Crohn's disease after surgery.

Wright, Emily K; Kamm, Michael A; De Cruz, Peter; Hamilton, Amy L; Ritchie, Kathryn J; Krejany, Efrosinia O; Leach, Steven; Gorelik, Alexandra; Liew, Danny; Prideaux, Lani; Lawrance, Ian C; Andrews, Jane M; Bampton, Peter A; Jakobovits, Simon L; Florin, Timothy H; Gibson, Peter R; Debinski, Henry; Macrae, Finlay A; Samuel, Douglas; Kronborg, Ian; Radford-Smith, Graeme; Selby, Warwick; Johnston, Michael J; Woods, Rodney; Elliott, P Ross; Bell, Sally J; Brown, Steven J; Connell, William R; Day, Andrew S; Desmond, Paul V; Gearry, Richard B.

Gastroenterology ; 148(5): 938-947.e1, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25620670

7.

Health and climate change.

Florin, Timothy H; Allen, David W.

Lancet ; 393(10187): 2196-2197, 2019 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-31162074

8.

Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease.

Doecke, James D; Simms, Lisa A; Zhao, Zhen Zhen; Roberts, Rebecca L; Fowler, Elizabeth V; Croft, Anthony; Lin, Angela; Huang, Ning; Whiteman, David C; Florin, Timothy H J; Barclay, Murray L; Merriman, Tony R; Gearry, Richard B; Montgomery, Grant W; Radford-Smith, Graham L.

J Gastroenterol Hepatol ; 30(2): 299-307, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24989722

9.

IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells.

Hasnain, Sumaira Z; Tauro, Sharyn; Das, Indrajit; Tong, Hui; Chen, Alice C-H; Jeffery, Penny L; McDonald, Victoria; Florin, Timothy H; McGuckin, Michael A.

Gastroenterology ; 144(2): 357-368.e9, 2013 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-23123183

10.

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity.

Oancea, Iulia; Png, Chin Wen; Das, Indrajit; Lourie, Rohan; Winkler, Ingrid G; Eri, Rajaraman; Subramaniam, Nathan; Jinnah, H A; McWhinney, Brett C; Levesque, Jean-Pierre; McGuckin, Michael A; Duley, John A; Florin, Timothy H J.

Gut ; 62(4): 594-605, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22773547

11.

MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier.

McGuckin, Michael A; Davies, Julie M; Felgner, Pascal; Wong, Kuan Yau; Giri, Rabina; He, Yaowu; Moniruzzaman, Md; Kryza, Thomas; Sajiir, Haressh; Hooper, John D; Florin, Timothy H; Begun, Jakob; Oussalah, Abderrahim; Hasnain, Sumaira Z; Hensel, Michael; Sheng, Yong H.

Cell Mol Gastroenterol Hepatol ; 16(6): 985-1009, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37660948

12.

An Extremes of Phenotype Approach Confirms Significant Genetic Heterogeneity in Patients with Ulcerative Colitis.

Mortlock, Sally; Lord, Anton; Montgomery, Grant; Zakrzewski, Martha; Simms, Lisa A; Krishnaprasad, Krupa; Hanigan, Katherine; Doecke, James D; Walsh, Alissa; Lawrance, Ian C; Bampton, Peter A; Andrews, Jane M; Mahy, Gillian; Connor, Susan J; Sparrow, Miles P; Bell, Sally; Florin, Timothy H; Begun, Jakob; Gearry, Richard B; Radford-Smith, Graham L.

J Crohns Colitis ; 17(2): 277-288, 2023 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-36111848

13.

Mucins in inflammatory bowel diseases and colorectal cancer.

Sheng, Yong H; Hasnain, Sumaira Z; Florin, Timothy H J; McGuckin, Michael A.

J Gastroenterol Hepatol ; 27(1): 28-38, 2012 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21913981

14.

The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis.

Sheng, Yong H; Lourie, Rohan; Lindén, Sara K; Jeffery, Penny L; Roche, Deborah; Tran, Thu V; Png, Chin W; Waterhouse, Nigel; Sutton, Philip; Florin, Timothy H J; McGuckin, Michael A.

Gut ; 60(12): 1661-70, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21636645

15.

Secreted NF-κB suppressive microbial metabolites modulate gut inflammation.

Giri, Rabina; Hoedt, Emily C; Khushi, Shamsunnahar; Salim, Angela A; Bergot, Anne-Sophie; Schreiber, Veronika; Thomas, Ranjeny; McGuckin, Michael A; Florin, Timothy H; Morrison, Mark; Capon, Robert J; Ó Cuív, Páraic; Begun, Jakob.

Cell Rep ; 39(2): 110646, 2022 04 12.

Artículo en Inglés | MEDLINE | ID: mdl-35417687

16.

MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Axis.

Sheng, Yong H; Davies, Julie M; Wang, Ran; Wong, Kuan Yau; Giri, Rabina; Yang, Yuanhao; Begun, Jakob; Florin, Timothy H; Hasnain, Sumaira Z; McGuckin, Michael A.

Cell Mol Gastroenterol Hepatol ; 14(4): 789-811, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35809803

17.

MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy.

Lindén, Sara K; Sheng, Yong H; Every, Alison L; Miles, Kim M; Skoog, Emma C; Florin, Timothy H J; Sutton, Philip; McGuckin, Michael A.

PLoS Pathog ; 5(10): e1000617, 2009 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-19816567

18.

Intestinal secretory cell ER stress and inflammation.

McGuckin, Michael A; Eri, Rajaraman D; Das, Indrajit; Lourie, Rohan; Florin, Timothy H.

Biochem Soc Trans ; 39(4): 1081-5, 2011 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-21787352

19.

Advances in Thiopurine Drug Delivery: The Current State-of-the-Art.

Bayoumy, Ahmed B; Crouwel, Femke; Chanda, Nripen; Florin, Timothy H J; Buiter, Hans J C; Mulder, Chris J J; de Boer, Nanne K H.

Eur J Drug Metab Pharmacokinet ; 46(6): 743-758, 2021 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-34487330

20.

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy.

Sheng, Yong Hua; Giri, Rabina; Davies, Julie; Schreiber, Veronika; Alabbas, Saleh; Movva, Ramya; He, Yaowu; Wu, Andy; Hooper, John; McWhinney, Brett; Oancea, Iulia; Kijanka, Gregor; Hasnain, Sumaira; Lucke, Andrew J; Fairlie, David P; McGuckin, Michael A; Florin, Timothy H; Begun, Jakob.

Cell Mol Gastroenterol Hepatol ; 11(1): 33-53, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-32497793

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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