1.
Molecules
; 9(3): 102-8, 2004 Feb 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-18007414
RESUMEN
A series of 9-(pyridin-2'-yl)-aminoacridines was prepared and analyzed for their ability to change the thermal denaturation temperature of genomic calf thymus DNA. Development of a QSAR equation indicated that electron withdrawing groups on the pyridine ring promoted the interaction with double stranded DNA.