RESUMEN
We studied three patients with schizencephaly and related the results of comprehensive neuropsychologic and speech/language assessments to the severity and location of the brain malformations as appreciated by magnetic resonance imaging. Level of general intellectual functioning related to the amount of brain tissue involved, and variations in specific neurobehavioral abilities reflected the location of the brain malformation and the prenatal onset of the disorder. The overall findings emphasize the importance of comprehensive neuropsychologic and speech/language studies for appreciating the impact of prenatal neural insult on the functional reorganization of the brain and subsequent neurobehavioral functioning.
Asunto(s)
Encéfalo/anomalías , Encéfalo/patología , Adolescente , Adulto , Femenino , Lateralidad Funcional , Humanos , Discapacidad Intelectual/diagnóstico , Trastornos del Lenguaje/diagnóstico , Pruebas del Lenguaje , Imagen por Resonancia Magnética , Masculino , Pruebas Neuropsicológicas , Desempeño PsicomotorRESUMEN
This article, aimed toward the nonneurologist specialist, presents current indications for MRI in the CNS. Primary and metastatic brain tumors, white matter disease, stroke and hemorrhage, hydrocephalus, and spinal disease are discussed. Emphasis is placed on the contribution of MRI to the evaluation of these major classes of disease. Because of its improved sensitivity and noninvasiveness, in most instances MRI is the initial imaging procedure of choice in the CNS.