RESUMEN
BACKGROUND: Lack of standardized assessments that explicitly quantify performance during prosthetic grip selection poses difficulty determining whether efforts to improve the design of multi-grip hands and their control approaches are successful. In this study, we developed and validated a novel assessment of multi-grip prosthetic performance: The Coffee Task. METHODS: Individuals without limb loss completed the Box and Block Test and two versions of the Coffee Task - Continuous and Segmented - with a myoelectric prosthetic emulator. On different days, participants selected prosthetic grips using pattern recognition and trigger control. Outcomes of the Continuous and Segmented Coffee Task were completion time and number of errors, respectively. Two independent raters assessed outcomes of the Coffee Task using video recordings to determine inter-rater reliability. Known-group validity was assessed by comparing outcomes with the emulator to those with an intact limb. Convergent validity was assessed through the correlation of the Coffee Task outcomes and those of the Box and Blocks Test. Responsiveness to changes with practice and control approach were assessed using the standardized response mean (SRM). RESULTS: Inter-rater reliability was high for both versions of the Coffee Task (Intra-class coefficient > 0.981). Coffee Task outcomes were moderately correlated with the Box and Blocks outcomes (|r| ≥ 0.412, p ≤ 0.007). Participants completed the Coffee Task faster with their intact limb than with the emulator (p < 0.001). Both versions of the Coffee Task were responsive to changes with training (SRM ≥ 0.81) but not control approach (SRM ≤ 0.12). CONCLUSIONS: The Coffee Task is reliable, has good known-group and convergent validity, and is responsive to changes due to practice. Future work should assess whether the Coffee Task is feasible and reliable for people with upper limb loss who use multi-grip prostheses.
Asunto(s)
Miembros Artificiales , Café , Humanos , Reproducibilidad de los Resultados , Extremidad Superior , Fuerza de la ManoRESUMEN
BACKGROUND: Patient access to body-powered and myoelectric upper limb prostheses in the United States is often restricted by a healthcare system that prioritizes prosthesis prescription based on cost and perceived value. Although this system operates on an underlying assumption that design differences between these prostheses leads to relative advantages and disadvantages of each device, there is limited empirical evidence to support this view. MAIN TEXT: This commentary article will review a series of studies conducted by our research team with the goal of differentiating how prosthesis design might impact user performance on a variety of interrelated domains. Our central hypothesis is that the design and actuation method of body-powered and myoelectric prostheses might affect users' ability to access sensory feedback and account for device properties when planning movements. Accordingly, other domains that depend on these abilities may also be affected. While our work demonstrated some differences in availability of sensory feedback based on prosthesis design, this did not result in consistent differences in prosthesis embodiment, movement accuracy, movement quality, and overall kinematic patterns. CONCLUSION: Collectively, our findings suggest that performance may not necessarily depend on prosthesis design, allowing users to be successful with either device type depending on the circumstances. Prescription practices should rely more on individual needs and preferences than cost or prosthesis design. However, we acknowledge that there remains a dearth of evidence to inform decision-making and that an expanded research focus in this area will be beneficial.
Asunto(s)
Miembros Artificiales , Diseño de Prótesis , Extremidad Superior , Humanos , Extremidad Superior/fisiología , Electromiografía/instrumentación , Retroalimentación Sensorial/fisiología , Fenómenos BiomecánicosRESUMEN
BACKGROUND: The mechanical properties of an ankle-foot orthosis (AFO) play an important role in the gait mechanics of the end user. However, testing methodologies for evaluating these mechanical properties are not standardized. The purpose of this study was to compare five different evaluation frameworks to assess AFO stiffness. METHOD: The same 13 carbon composite AFOs were tested with five different methods. Four previously reported custom test fixtures (the BRUCE, KST, SMApp, and EMPIRE) rotated an AFO into dorsiflexion about a defined axis in the sagittal plane. The fifth method involved quasi-static deflection of AFOs into dorsiflexion by hanging weights (HW) from the footplate. AFO rotational stiffness was calculated as the linear fit of the AFO resistive torque and angular deflection. Differences between methods were assessed using descriptive statistics and a repeated measures Friedman with post-hoc Bonferroni-Holm adjusted Wilcoxon signed-rank tests. RESULTS: There were significant differences in measured AFO stiffnesses between test methods. Specifically, the BRUCE and HW methods measured lower stiffness than both the EMPIRE and the KST. Stiffnesses measured by the SMApp were not significantly different than any test method. Stiffnesses were lowest in the HW method, where motion was not constrained to a single plane. The median difference in absolute AFO stiffness across methods was 1.03 Nm/deg with a range of [0.40 to 2.35] Nm/deg. The median relative percent difference, measured as the range of measured stiffness from the five methods over the average measured stiffness was 62% [range 13% to 156%]. When the HW method was excluded, the four previously reported test fixtures produced a median difference in absolute AFO stiffness of 0.52 [range 0.38 to 2.17] Nm/deg with a relative percent difference between the methods of 27% [range 13% to 89%]. CONCLUSIONS: This study demonstrates the importance of developing mechanical testing standards, similar to those that exist for lower limb prosthetics. Lacking standardization, differences in methodology can result in large differences in measured stiffness, particularly for different constraints on motion. Non-uniform measurement practices may limit the clinical utility of AFO stiffness as a metric in AFO prescription and future research.
Asunto(s)
Tobillo , Ortesis del Pié , Humanos , Articulación del Tobillo , Marcha , Proyectos de Investigación , Fenómenos Biomecánicos , Rango del Movimiento ArticularRESUMEN
Understanding the fundamental characteristics of prosthetic movement control is imperative in improving prosthesis design and training. This study quantified how using an upper limb prosthesis affected performance during goal-directed reaching tasks. Nine prosthesis users with unilateral transradial limb absence and nine healthy controls completed a series of goal-directed reaching movements with different goals: one spatial and three temporal with different goal frequencies. We quantified end-point accuracy, smoothness, and peak speed for the spatial task and temporal accuracy, horizontal distance, and speed for the temporal task. For the temporal task, we also used a goal-equivalent manifold (GEM) approach to decompose variability in movement distance and speed into those perpendicular and tangential to the GEM. Detrended fluctuation analysis (DFA) quantified the temporal persistence of each time series. For the spatial task, movements made with prostheses were less smooth, had larger end-point errors, and had slower peak speed compared to those with control limbs (p < 0.041). For the temporal task, movements made with prostheses and intact limbs of prosthesis users and control limbs were similar in distance and speed and had similar timing errors (p > 0.138). Timing errors, distance, speed, and GEM deviations were corrected similarly between prosthetic limbs and control limbs (p > 0.091). The mean and variability of distance, speed, and perpendicular deviations decreased with increased goal frequency (p < 0.001). Our results suggest that prosthesis users have a sufficient internal model to successfully complete ballistic movements but are unable to accurately complete movements requiring substantial feedback.
Asunto(s)
Miembros Artificiales , Humanos , Objetivos , Extremidad Superior , Movimiento , Factores de TiempoRESUMEN
Currently available prosthetic hands are capable of actuating anywhere from five to 30 degrees of freedom (DOF). However, grasp control of these devices remains unintuitive and cumbersome. To address this issue, we propose directly extracting finger commands from the neuromuscular system. Two persons with transradial amputations had bipolar electrodes implanted into regenerative peripheral nerve interfaces (RPNIs) and residual innervated muscles. The implanted electrodes recorded local electromyography with large signal amplitudes. In a series of single-day experiments, participants used a high speed movement classifier to control a virtual prosthetic hand in real-time. Both participants transitioned between 10 pseudo-randomly cued individual finger and wrist postures with an average success rate of 94.7% and trial latency of 255 ms. When the set was reduced to five grasp postures, metrics improved to 100% success and 135 ms trial latency. Performance remained stable across untrained static arm positions while supporting the weight of the prosthesis. Participants also used the high speed classifier to switch between robotic prosthetic grips and complete a functional performance assessment. These results demonstrate that pattern recognition systems can use intramuscular electrodes and RPNIs for fast and accurate prosthetic grasp control.
RESUMEN
BACKGROUND: Powered prosthetic ankles provide battery-powered mechanical push-off, with the aim of reducing the metabolic demands of walking for people with transtibial amputations. The efficacy of powered ankles has been shown in active, high functioning individuals with transtibial amputation, but is less clear in other populations. Additionally, it is unclear how use of a powered prosthesis influences everyday physical activity and mobility. METHODS: Individuals with unilateral transtibial amputations participated in a randomized clinical trial comparing their prescribed, unpowered prosthesis and the BiOM powered prosthesis. Participants' metabolic costs and self-selected walking speeds were measured in the laboratory and daily step count, daily steps away from home, and walking speed were measured over two weeks of at-home prosthesis use. Participants also rated their perception of mobility and quality of life and provided free-form feedback. Dependent measures were compared between prostheses and the relationships between metabolic cost, perception of mobility, and characteristics of walking in daily life were explored using Pearson's correlations. RESULTS: Twelve people were randomly allocated to the powered prosthesis first (n = 7) or unpowered prosthesis first (n = 5) and ten completed the full study. There were no differences in metabolic costs (p = 0.585), daily step count (p = 0.995), walking speed in-lab (p = 0.145) and in daily life (p = 0.226), or perception of mobility between prostheses (p ≥ 0.058). Changes varied across participants, however. There were several medium-sized effects for device comparisons. With the powered prosthesis, participants had increased self-reported ambulation (g = 0.682) and decreased frustration (g = 0.506). CONCLUSIONS: There were no universal benefits of the powered prosthesis on function in the lab or home environment. However, the effects were subject-specific, with some reporting preference for power and improved mobility, and some increasing their activity and decreasing their metabolic effort. Additionally, self-reported preferences did not often correlate with objective measures of function. This highlights the need for future clinical research to include both perception and objective measures to better inform prosthetic prescription. TRIAL REGISTRATION: https://clinicaltrials.gov , #NCT02828982. Registered 12 July 2016, https://clinicaltrials.gov/ct2/show/NCT02828982.
Asunto(s)
Articulación del Tobillo/fisiopatología , Miembros Artificiales , Prioridad del Paciente , Esfuerzo Físico/fisiología , Caminata/fisiología , Adulto , Anciano , Fenómenos Biomecánicos , Estudios Cruzados , Femenino , Humanos , Pierna , Masculino , Persona de Mediana Edad , Calidad de VidaRESUMEN
During fatiguing tasks, people adapt their movement strategies to offset effects of muscle fatigue. Painful stimuli may compete for cognitive resources during this process, impairing fatigue adaptation. This study determined how pain affected movement control and muscle endurance during a repetitive task and how pain catastrophizing moderated these effects. Twenty-two healthy young adults performed timed reaching movements until voluntary exhaustion on two separate days. On 1 day, subjects simultaneously experienced ischemic pain in the contralateral arm. Subjective pain, and effort were recorded at regular intervals. Timing errors, distance and speed were calculated for each movement. Detrended fluctuation analysis was used to quantify temporal persistence in each time series. Subjects made shorter, slower movements during the last compared to the first minute of fatigue on both days (p < 0.001). Deviations in movement speed were corrected faster in the no pain condition compared to the pain condition (p = 0.042), but only early during the condition. Time to fatigue was influenced by pain and the order of testing. Subjects performed the task longer on the second day whether the condition was pain or no pain. This effect was larger when the pain condition was first (3.4 compared to 1.1 min. increase). Subjects with high and low pain catastrophizing responded similarly to the painful stimuli. The results suggest that pain causes people to adopt more conservative movement strategies which can affect the fatigue rate, but these effects depend on familiarity with the painful stimulus and the fatiguing task.
Asunto(s)
Catastrofización/fisiopatología , Actividad Motora/fisiología , Fatiga Muscular/fisiología , Músculo Esquelético/fisiología , Dolor/fisiopatología , Resistencia Física/fisiología , Adulto , Femenino , Humanos , Masculino , Factores de Tiempo , Adulto JovenRESUMEN
OBJECTIVE: To determine whether there are changes in level walking performance for people using a powered ankle prosthesis that was tuned by an independent, manufacturer-certified prosthetist in accordance with device recommendations. DESIGN: Intervention study with cross-over design. SETTING: Laboratory. PARTICIPANTS: Convenience sample of 10 individuals with unilateral, transtibial amputation, and 10 age- and gender-matched control participants. INTERVENTIONS: Powered ankle prosthesis (BiOM T2 Ankle System). Main outcome metrics: Metabolic costs of walking, preferred walking speed. RESULTS: There were no significant differences in oxygen consumption (2.9% difference; P = 0.606, d = 0.26), cost of transport (~1% difference; P = 0.652, d = 0.23), or preferred walking speed (~1% difference; P = 0.147, d = 0.76) when using the powered ankle compared to unpowered prostheses. Secondary analyses of user characteristics revealed that participants who were classified as having the highest function (K4 on Medicare's 5-point scale from K0 to K4) were significantly more likely to exhibit energy cost savings than those classified as having lower function (K3; P = 0.014, d = 2.36). CONCLUSIONS: Participants did not demonstrate significant improvements in energetics or preferred speed when wearing a clinically tuned powered ankle prosthesis compared to their non-powered prostheses. Prescribers of powered devices should understand that not all users will show an immediate reduction in energy expenditure.
Asunto(s)
Amputación Quirúrgica/métodos , Miembros Artificiales , Prótesis Articulares , Diseño de Prótesis , Velocidad al Caminar/fisiología , Adulto , Articulación del Tobillo/cirugía , Índice de Masa Corporal , Intervalos de Confianza , Estudios Cruzados , Metabolismo Energético , Humanos , Masculino , Persona de Mediana Edad , Consumo de Oxígeno/fisiología , Valores de Referencia , Tibia/cirugía , Caminata/fisiologíaRESUMEN
During grasping, the median nerve undergoes mechanical stress in the carpal tunnel which may contribute to carpal tunnel syndrome. This study investigated the effects of wrist posture, grip type, and grip force on the shape and cross-sectional area of the median nerve. Ultrasound examination was used to obtain cross-sectional images of the dominant wrist of 16 healthy subjects (8 male) at the proximal carpal tunnel during grasping. The cross-sectional area, circularity, and axis lengths of the median nerve were assessed in 27 different conditions (3 postures × 3 grip types × 3 force levels). There were no significant changes in median nerve cross-sectional area (P > 0.05). There were significant interactions across posture, grip type, and grip force affecting nerve circularity and axis lengths. When the wrist was flexed, increasing grip force caused the median nerve to shorten in the mediolateral direction and lengthen in the anteroposterior direction (P < 0.04), becoming more circular. These effects were significant during four finger pinch grip and chuck grip (P < 0.05) but not key grip (P > 0.07). With the wrist extended, the nerve became more flattened (less circular) as grip force increased during four finger pinch grip and chuck grip (P < 0.04) but not key grip (P > 0.3). Circularity was lower during the four finger pinch compared to chuck or key grip (P < 0.03). The findings suggest that grip type and wrist posture significantly alter the shape of the median nerve. Clin. Anat. 30:470-478, 2017. © 2017 Wiley Periodicals, Inc.
Asunto(s)
Fuerza de la Mano/fisiología , Nervio Mediano/anatomía & histología , Postura , Muñeca/fisiología , Femenino , Voluntarios Sanos , Humanos , Masculino , Curva ROC , Ultrasonografía , Muñeca/anatomía & histología , Adulto JovenRESUMEN
OBJECTIVE: We quantified the range of motion (ROM) required for eight upper-extremity activities of daily living (ADLs) in healthy participants. METHOD: Fifteen right-handed participants completed several bimanual and unilateral basic ADLs while joint kinematics were monitored using a motion capture system. Peak motions of the pelvis, trunk, shoulder, elbow, and wrist were quantified for each task. RESULTS: To complete all activities tested, participants needed a minimum ROM of -65°/0°/105° for humeral plane angle (horizontal abduction-adduction), 0°-108° for humeral elevation, -55°/0°/79° for humeral rotation, 0°-121° for elbow flexion, -53°/0°/13° for forearm rotation, -40°/0°/38° for wrist flexion-extension, and -28°/0°/38° for wrist ulnar-radial deviation. Peak trunk ROM was 23° lean, 32° axial rotation, and 59° flexion-extension. CONCLUSION: Full upper-limb kinematics were calculated for several ADLs. This methodology can be used in future studies as a basis for developing normative databases of upper-extremity motions and evaluating pathology in populations.
Asunto(s)
Actividades Cotidianas , Articulación del Codo/fisiopatología , Rango del Movimiento Articular , Articulación del Hombro/fisiopatología , Extremidad Superior/fisiopatología , Fenómenos Biomecánicos , Femenino , Antebrazo/fisiopatología , Articulación de la Cadera/fisiopatología , Humanos , Masculino , Pronación/fisiología , Rotación , Columna Vertebral/fisiopatología , Análisis y Desempeño de Tareas , Articulación de la Muñeca/fisiopatología , Adulto JovenRESUMEN
BACKGROUND: Novel techniques for the control of upper limb prostheses may allow users to operate more complex prostheses than those that are currently available. Because many of these techniques are surgically invasive, it is important to understand whether individuals with upper limb loss would accept the associated risks in order to use a prosthesis. METHODS: An online survey of individuals with upper limb loss was conducted. Participants read descriptions of four prosthetic control techniques. One technique was noninvasive (myoelectric) and three were invasive (targeted muscle reinnervation, peripheral nerve interfaces, cortical interfaces). Participants rated how likely they were to try each technique if it offered each of six different functional features. They also rated their general interest in each of the six features. A two-way repeated measures analysis of variance with Greenhouse-Geisser corrections was used to examine the effect of the technique type and feature on participants' interest in each technique. RESULTS: Responses from 104 individuals were analyzed. Many participants were interested in trying the techniques - 83 % responded positively toward myoelectric control, 63 % toward targeted muscle reinnervation, 68 % toward peripheral nerve interfaces, and 39 % toward cortical interfaces. Common concerns about myoelectric control were weight, cost, durability, and difficulty of use, while the most common concern about the invasive techniques was surgical risk. Participants expressed greatest interest in basic prosthesis features (e.g., opening and closing the hand slowly), as opposed to advanced features like fine motor control and touch sensation. CONCLUSIONS: The results of these investigations may be used to inform the development of future prosthetic technologies that are appealing to individuals with upper limb loss.
Asunto(s)
Miembros Artificiales , Extremidad Superior , Adulto , Anciano , Anciano de 80 o más Años , Amputados , Interfaces Cerebro-Computador , Corteza Cerebral , Escolaridad , Femenino , Mano , Humanos , Masculino , Persona de Mediana Edad , Músculo Esquelético/inervación , Prótesis Neurales , Satisfacción del Paciente , Nervios Periféricos , Diseño de Prótesis , Encuestas y Cuestionarios , Interfaz Usuario-Computador , Adulto JovenRESUMEN
Repetitive movements can cause muscle fatigue, leading to motor reorganization, performance deficits, and/or possible injury. The effects of fatigue may depend on the type of fatigue task employed, however. The purpose of this study was to determine how local fatigue of a specific muscle group versus widespread fatigue of various muscle groups affected the control of movement timing. Twenty healthy subjects performed an upper extremity low-load work task similar to sawing for 5 continuous minutes both before and after completing a protocol that either fatigued all the muscles used in the task (widespread fatigue) or a protocol that selectively fatigued the primary muscles used to execute the pushing stroke of the sawing task (localized fatigue). Subjects were instructed to time their movements with a metronome. Timing error, movement distance, and speed were calculated for each movement. Data were then analyzed using a goal-equivalent manifold approach to quantify changes in goal-relevant and non-goal-relevant variability. We applied detrended fluctuation analysis to each time series to quantify changes in fluctuation dynamics that reflected changes in the control strategies used. After localized fatigue, subjects made shorter, slower movements and exerted greater control over non-goal-relevant variability. After widespread fatigue, subjects exerted less control over non-goal-relevant variability and did not change movement patterns. Thus, localized and widespread muscle fatigue affected movement differently. Local fatigue may reduce the available motor solutions and therefore cause greater movement reorganization than widespread muscle fatigue. Subjects altered their control strategies but continued to achieve the timing goal after both fatigue tasks.
Asunto(s)
Movimiento/fisiología , Contracción Muscular/fisiología , Fatiga Muscular/fisiología , Músculo Esquelético/fisiología , Adulto , Fenómenos Biomecánicos/fisiología , Electromiografía , Femenino , Humanos , Masculino , Factores de Tiempo , Adulto JovenRESUMEN
While healthy individuals have redundant degrees of freedom of the joints, they coordinate their multi-joint movements such that the redundancy is effectively reduced. Achieving high inter-joint coordination may be difficult for upper limb prosthesis users due to the lack of proprioceptive feedback and limited motion of the terminal device. This study compared inter-joint coordination between prosthesis users and individuals without limb loss during different upper limb activities of daily living (ADLs). Nine unilateral prosthesis users (five males) and nine age- and sex-matched controls without limb loss completed three unilateral and three bilateral ADLs. Principal component analysis was applied to the three-dimensional motion trajectories of the trunk and arms to identify coordinative patterns. For each ADL, we quantified the cumulative variance accounted for (VAF) of the first five principal components (pcs), which was the lowest number of pcs that could achieve 90% VAF in control limb movements across all ADLs (5 ≤ n ≤ 9). The VAF was lower for movements involving a prosthesis compared to those completed by controls across all ADLs (p < 0.001). The pc waveforms were similar between movements involving a prosthesis and movements completed by control participants for pc1 (r > 0.78, p < 0.001). The magnitude of the relationship for pc2 and pc3 differed between ADLs, with the strongest correlation for symmetric bilateral ADLs (0.67 ≤ r ≤ 0.97, p < 0.001). Collectively, this study demonstrates that activities of daily living were completed with distinct coordination strategies in prosthesis users compared to individuals without limb loss. Future work should explore how device features, such as the availability of sensory feedback or motorized wrist joints influence multi-joint coordination.
Asunto(s)
Actividades Cotidianas , Miembros Artificiales , Análisis de Componente Principal , Humanos , Masculino , Femenino , Persona de Mediana Edad , Adulto , Fenómenos Biomecánicos , Extremidad Superior , Anciano , Desempeño Psicomotor/fisiología , AmputadosRESUMEN
Individuals with upper limb loss lack sensation of the missing hand, which can negatively impact their daily function. Several groups have attempted to restore this sensation through electrical stimulation of residual nerves. The purpose of this study was to explore the utility of regenerative peripheral nerve interfaces (RPNIs) in eliciting referred sensation. In four participants with upper limb loss, we characterized the quality and location of sensation elicited through electrical stimulation of RPNIs over time. We also measured functional stimulation ranges (sensory perception and discomfort thresholds), sensitivity to changes in stimulation amplitude, and ability to differentiate objects of different stiffness and sizes. Over a period of up to 54 months, stimulation of RPNIs elicited sensations that were consistent in quality (e.g. tingling, kinesthesia) and were perceived in the missing hand and forearm. The location of elicited sensation was partially-stable to stable in 13 of 14 RPNIs. For 5 of 7 RPNIs tested, participants demonstrated a sensitivity to changes in stimulation amplitude, with an average just noticeable difference of 45 nC. In a case study, one participant was provided RPNI stimulation proportional to prosthetic grip force. She identified four objects of different sizes and stiffness with 56% accuracy with stimulation alone and 100% accuracy when stimulation was combined with visual feedback of hand position. Collectively, these experiments suggest that RPNIs have the potential to be used in future bi-directional prosthetic systems.
Asunto(s)
Miembros Artificiales , Nervios Periféricos , Femenino , Humanos , Nervios Periféricos/fisiología , Extremidad Superior , Sensación , Mano , Estimulación EléctricaRESUMEN
Due to the loss of ankle function, many people with a transtibial amputation (TTA) have difficulty maintaining balance during functional tasks. Prosthetic alignment may affect how people with TTA maintain balance as it affects ground reaction forces (GRFs) and centers of pressure. We quantified the effect of prosthetic alignment on dynamic balance during several functional tasks. Ten people with TTA and 10 controls without TTA completed tasks including walking and transitioning from a chair. Participants with TTA completed all tasks with their prescribed alignment and six shifted alignments, including ±10 mm anterior/posterior, medial/lateral, and ±20 mm in the vertical direction. For each task, we quantified dynamic balance as the range of whole-body angular momentum (HâWB) and quantified trunk range of motion (ROM) and peak GRFs. Compared to controls, participants with TTA using their prescribed alignment had a greater range of HâWB in the sagittal plane during walking, in all planes during sit-to-stand, and in the transverse plane during stand-to-sit. These results were associated with GRF and trunk ROM differences between participant groups. Alignment only affected the range of HâWB in the frontal plane during walking. The larger range for the tall alignment coincided with a greater difference in vertical GRF between intact and amputated legs compared to other alignments. Our findings suggest that people with TTA can adapt to small, translational, alignment changes to maintain similar levels of dynamic balance during chair transitions. Future work should investigate alignment changes during other tasks and in lower functioning individuals.
Asunto(s)
Miembros Artificiales , Marcha , Humanos , Fenómenos Biomecánicos , Caminata , Amputación QuirúrgicaRESUMEN
Replacing human hand function with prostheses goes far beyond only recreating muscle movement with feedforward motor control. Natural sensory feedback is pivotal for fine dexterous control and finding both engineering and surgical solutions to replace this complex biological function is imperative to achieve prosthetic hand function that matches the human hand. This review outlines the nature of the problems underlying sensory restitution, the engineering methods that attempt to address this deficit and the surgical techniques that have been developed to integrate advanced neural interfaces with biological systems. Currently, there is no single solution to restore sensory feedback. Rather, encouraging animal models and early human studies have demonstrated that some elements of sensation can be restored to improve prosthetic control. However, these techniques are limited to highly specialized institutions and much further work is required to reproduce the results achieved, with the goal of increasing availability of advanced closed loop prostheses that allow sensory feedback to inform more precise feedforward control movements and increase functionality.
Asunto(s)
Miembros Artificiales , Animales , Humanos , Extremidad Superior/cirugía , Mano/cirugía , Mano/fisiología , Sensación , Retroalimentación Sensorial , Diseño de PrótesisRESUMEN
Objective.Extracting signals directly from the motor system poses challenges in obtaining both high amplitude and sustainable signals for upper-limb neuroprosthetic control. To translate neural interfaces into the clinical space, these interfaces must provide consistent signals and prosthetic performance.Approach.Previously, we have demonstrated that the Regenerative Peripheral Nerve Interface (RPNI) is a biologically stable, bioamplifier of efferent motor action potentials. Here, we assessed the signal reliability from electrodes surgically implanted in RPNIs and residual innervated muscles in humans for long-term prosthetic control.Main results.RPNI signal quality, measured as signal-to-noise ratio, remained greater than 15 for up to 276 and 1054 d in participant 1 (P1), and participant 2 (P2), respectively. Electromyography from both RPNIs and residual muscles was used to decode finger and grasp movements. Though signal amplitude varied between sessions, P2 maintained real-time prosthetic performance above 94% accuracy for 604 d without recalibration. Additionally, P2 completed a real-world multi-sequence coffee task with 99% accuracy for 611 d without recalibration.Significance.This study demonstrates the potential of RPNIs and implanted EMG electrodes as a long-term interface for enhanced prosthetic control.
Asunto(s)
Miembros Artificiales , Nervios Periféricos , Humanos , Reproducibilidad de los Resultados , Nervios Periféricos/fisiología , Extremidad Superior , Electromiografía/métodos , Electrodos Implantados , ElectrodosRESUMEN
BACKGROUND: Due to increased interest in treadmill gait training, recent research has focused on the similarities and differences between treadmill and overground walking. Most of these studies have tested healthy, young subjects rather than impaired populations that might benefit from such training. These studies also do not include optic flow, which may change how the individuals integrate sensory information when walking on a treadmill. This study compared overground walking to treadmill walking in a computer assisted virtual reality environment (CAREN) in individuals with and without transtibial amputations (TTA). METHODS: Seven individuals with traumatic TTA and 27 unimpaired controls participated. Subjects walked overground and on a treadmill in a CAREN at a normalized speed. The CAREN applied optic flow at the same speed that the subject walked. Temporal-spatial parameters, full body kinematics, and kinematic variability were collected during all trials. RESULTS: Both subject groups decreased step time and control subjects decreased step length when walking in the CAREN. Differences in lower extremity kinematics were small (< 2.5(â)) and did not exceed the minimal detectable change values for these measures. Control subjects exhibited decreased transverse and frontal plane range of motion of the pelvis and trunk when walking in the CAREN, while patients with TTA did not. Both groups exhibited increased step width variability during treadmill walking in the CAREN, but only minor changes in kinematic variability. CONCLUSIONS: The results of this study suggest that treadmill training in a virtual environment should be similar enough to overground that changes should carry over. Caution should be made when comparing step width variability and step time results from studies utilizing a treadmill to those overground.
Asunto(s)
Amputación Quirúrgica/rehabilitación , Tibia , Caminata/fisiología , Adulto , Fenómenos Biomecánicos , Interpretación Estadística de Datos , Femenino , Humanos , Articulaciones/fisiología , Extremidad Inferior/fisiología , Masculino , Movimiento (Física) , Pelvis/fisiología , Educación y Entrenamiento Físico , Rango del Movimiento Articular , Tórax/fisiología , Interfaz Usuario-Computador , Adulto JovenRESUMEN
BACKGROUND: People with upper limb absence use compensatory movements to accommodate lack of motion in the prosthetic hand. The purpose of this study was to determine if the type of prosthesis used (i.e. body-powered or myoelectric) affects compensatory movements during activities of daily living. METHODS: Twelve transradial body-powered and/or myoelectric prosthesis users performed up to six unimanual and bimanual activities of daily living. Trunk range of motion and peak upper limb angles for each task were compared between prostheses. FINDINGS: Compensatory movement generally did not differ based on prosthesis type. However, body-powered users had increased trunk lateral lean compared to myoelectric users during a deodorant application task (P = 0.025). Body-powered users also had increased trunk axial rotation (P = 0.048) and decreased shoulder elevation (P = 0.046) when transferring a box between shelves. Compensatory movements were not systematically correlated with duration of prosthesis ownership, socket comfort, or terminal device type. INTERPRETATION: A prosthesis user's compensatory movements may depend on other factors beyond whether the prosthesis terminal device is actuated through body-powered or myoelectric mechanisms. Further exploration of the factors that influence joint kinematics in prosthesis users may inform future prosthesis prescription practices and help patients become successful users.
Asunto(s)
Amputados , Miembros Artificiales , Actividades Cotidianas , Humanos , Movimiento , Diseño de Prótesis , Implantación de Prótesis , Extremidad SuperiorRESUMEN
Objective.Electrical stimulation can induce sensation in the phantom limb of individuals with amputation. It is difficult to generalize existing findings as there are many approaches to delivering stimulation and to assessing the characteristics and benefits of sensation. Therefore, the goal of this systematic review was to explore the stimulation parameters that effectively elicited referred sensation, the qualities of elicited sensation, and how the utility of referred sensation was assessed.Approach.We searched PubMed, Web of Science, and Engineering Village through January of 2022 to identify relevant papers. We included papers which electrically induced referred sensation in individuals with limb loss and excluded papers that did not contain stimulation parameters or outcome measures pertaining to stimulation. We extracted information on participant demographics, stimulation approaches, and participant outcomes.Main results.After applying exclusion criteria, 49 papers were included covering nine stimulation methods. Amplitude was the most commonly adjusted parameter (n= 25), followed by frequency (n= 22), and pulse width (n= 15). Of the 63 reports of sensation quality, most reported feelings of pressure (n= 52), paresthesia (n= 48), or vibration (n= 40) while less than half (n= 29) reported a sense of position or movement. Most papers evaluated the functional benefits of sensation (n= 33) using force matching or object identification tasks, while fewer papers quantified subjective measures (n= 16) such as pain or embodiment. Only 15 studies (36%) observed percept intensity, quality, or location over multiple sessions.Significance.Most studies that measured functional performance demonstrated some benefit to providing participants with sensory feedback. However, few studies could experimentally manipulate sensation location or quality. Direct comparisons between studies were limited by variability in methodologies and outcome measures. As such, we offer recommendations to aid in more standardized reporting for future research.