Neural representations of confidence emerge from the process of decision formation during perceptual choices.

Choice confidence represents the degree of belief that one's actions are likely to be correct or rewarding and plays a critical role in optimizing our decisions. Despite progress in understanding the neurobiology of human perceptual decision-making, little is known about the representation of confidence. Importantly, it remains unclear whether confidence forms an integral part of the decision process itself or represents a purely post-decisional signal. To address this issue we employed a paradigm whereby on some trials, prior to indicating their decision, participants could opt-out of the task for a small but certain reward. This manipulation captured participants' confidence on individual trials and allowed us to discriminate between electroencephalographic signals associated with certain-vs.-uncertain trials. Discrimination increased gradually and peaked well before participants indicated their choice. These signals exhibited a temporal profile consistent with a process of evidence accumulation, culminating at time of peak discrimination. Moreover, trial-by-trial fluctuations in the accumulation rate of nominally identical stimuli were predictive of participants' likelihood to opt-out of the task, suggesting that confidence emerges from the decision process itself and is computed continuously as the process unfolds. Correspondingly, source reconstruction placed these signals in regions previously implicated in decision making, within the prefrontal and parietal cortices. Crucially, control analyses ensured that these results could not be explained by stimulus difficulty, lapses in attention or decision accuracy.

Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions.

Neural representations of perceptual decision formation that are abstracted from specific motor requirements have previously been identified in humans using non-invasive electrophysiology; however, it is currently unclear where these originate in the brain. Here we capitalized on the high spatiotemporal precision of intracranial EEG to localize such abstract decision signals. Participants undergoing invasive electrophysiological monitoring for epilepsy were asked to judge the direction of random-dot stimuli and respond either with a speeded button press (N = 24), or vocally, after a randomized delay (N = 12). We found a widely distributed motor-independent network of regions where high-frequency activity exhibited key characteristics consistent with evidence accumulation, including a gradual buildup that was modulated by the strength of the sensory evidence, and an amplitude that predicted participants' choice accuracy and response time. Our findings offer a new view on the brain networks governing human decision-making.

The Confidence Database.

Understanding how people rate their confidence is critical for the characterization of a wide range of perceptual, memory, motor and cognitive processes. To enable the continued exploration of these processes, we created a large database of confidence studies spanning a broad set of paradigms, participant populations and fields of study. The data from each study are structured in a common, easy-to-use format that can be easily imported and analysed using multiple software packages. Each dataset is accompanied by an explanation regarding the nature of the collected data. At the time of publication, the Confidence Database (which is available at https://osf.io/s46pr/) contained 145 datasets with data from more than 8,700 participants and almost 4 million trials. The database will remain open for new submissions indefinitely and is expected to continue to grow. Here we show the usefulness of this large collection of datasets in four different analyses that provide precise estimations of several foundational confidence-related effects.

Human VMPFC encodes early signatures of confidence in perceptual decisions.

Choice confidence, an individual's internal estimate of judgment accuracy, plays a critical role in adaptive behaviour, yet its neural representations during decision formation remain underexplored. Here, we recorded simultaneous EEG-fMRI while participants performed a direction discrimination task and rated their confidence on each trial. Using multivariate single-trial discriminant analysis of the EEG, we identified a stimulus-independent component encoding confidence, which appeared prior to subjects' explicit choice and confidence report, and was consistent with a confidence measure predicted by an accumulation-to-bound model of decision-making. Importantly, trial-to-trial variability in this electrophysiologically-derived confidence signal was uniquely associated with fMRI responses in the ventromedial prefrontal cortex (VMPFC), a region not typically associated with confidence for perceptual decisions. Furthermore, activity in the VMPFC was functionally coupled with regions of the frontal cortex linked to perceptual decision-making and metacognition. Our results suggest that the VMPFC holds an early confidence representation arising from decision dynamics, preceding and potentially informing metacognitive evaluation.