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1.
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial.
Respir Res
; 23(1): 202, 2022 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35945604
2.
Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study.
Ann Rheum Dis
; 78(8): 1033-1040, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31177099
3.
Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation.
Ann Rheum Dis
; 77(4): 523-532, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29275332
4.
First-in-human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL-17A and IL-17F, in mild psoriasis.
Br J Clin Pharmacol
; 83(5): 991-1001, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27859546
5.
Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.
J Pharmacol Exp Ther
; 351(2): 259-69, 2014 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25125580
6.
Efficacy and Safety of Bimekizumab in Moderate to Severe Hidradenitis Suppurativa: A Phase 2, Double-blind, Placebo-Controlled Randomized Clinical Trial.
JAMA Dermatol
; 157(11): 1279-1288, 2021 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34406364
7.
Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice.
Eur J Cancer
; 44(1): 142-50, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18039567
8.
A program for individual and population optimal design for univariate and multivariate response pharmacokinetic-pharmacodynamic models.
Comput Methods Programs Biomed
; 86(1): 51-61, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17292995
9.
A cross-species translational pharmacokinetic-pharmacodynamic evaluation of core body temperature reduction by the TRPM8 blocker PF-05105679.
Eur J Pharm Sci
; 109S: S161-S167, 2017 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28603038
10.
Population pharmacokinetics of onercept in healthy subjects.
Clin Pharmacokinet
; 44(12): 1295-304, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16372827
11.
Characterization of a surrogate murine antibody to model anti-human CD3 therapies.
MAbs
; 5(4): 555-64, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23751612
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