Detalles de la búsqueda
1.
Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.
Exp Aging Res
; : 1-16, 2022 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36545820
2.
Diet enriched in omega-3 fatty acids alleviates olfactory system deficits in APOE4 transgenic mice.
Eur J Neurosci
; 54(9): 7092-7108, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34549475
3.
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.
Hum Mol Genet
; 25(8): 1600-18, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26908611
4.
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Genome Res
; 25(5): 701-13, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25908449
5.
Activation of caspase-6 and cleavage of caspase-6 substrates is an early event in NMDA receptor-mediated excitotoxicity.
J Neurosci Res
; 96(3): 391-406, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29193273
6.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Hum Mol Genet
; 23(15): 4142-60, 2014 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24705354
7.
Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.
Biogerontology
; 17(5-6): 817-828, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27465500
8.
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice.
Neurobiol Dis
; 76: 24-36, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25583186
9.
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice.
Hum Mol Genet
; 21(9): 1954-67, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22262731
10.
Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.
J Neurosci
; 32(1): 183-93, 2012 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-22219281
11.
Specific olfactory deficit patterns observed in seniors and associated with cognitive decline.
Prog Neuropsychopharmacol Biol Psychiatry
; 126: 110775, 2023 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37120003
12.
Amelioration of Cognitive and Olfactory System Deficits in APOE4 Transgenic Mice with DHA Treatment.
Mol Neurobiol
; 60(10): 5624-5641, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37329383
13.
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.
Neurobiol Dis
; 48(3): 282-9, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22796360
14.
Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression.
Hum Mol Genet
; 19(8): 1528-38, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20097678
15.
Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.
J Neurosci
; 30(43): 14318-29, 2010 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20980587
16.
Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.
J Neurosci
; 30(45): 15019-29, 2010 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21068307
17.
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease.
J Neurosci
; 29(7): 2193-204, 2009 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-19228972
18.
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.
Hum Mol Genet
; 17(17): 2738-51, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18558632
19.
Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus.
Hum Mol Genet
; 17(15): 2390-404, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18445618
20.
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin.
Brain
; 132(Pt 4): 919-32, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19224899