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1.
Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial.
Haematologica
; 97(5): 731-8, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22315495
2.
Correction to: Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer.
Target Oncol
; 15(6): 803, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33108585
3.
Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer.
Target Oncol
; 15(2): 163-174, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32314268
4.
On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.
Mol Cancer Ther
; 19(2): 468-478, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31619463
5.
Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 867(1): 105-10, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18417430
6.
Pharmacokinetics of intravenous pan-class I phosphatidylinositol 3-kinase (PI3K) inhibitor [14C]copanlisib (BAY 80-6946) in a mass balance study in healthy male volunteers.
Cancer Chemother Pharmacol
; 80(3): 535-544, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28714036
7.
A phase I, multicenter, open-label, first-in-human, dose-escalation study of the oral smoothened inhibitor Sonidegib (LDE225) in patients with advanced solid tumors.
Clin Cancer Res
; 20(7): 1900-9, 2014 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24523439
8.
Development and validation of a liquid chromatography-tandem mass spectrometry assay for the simultaneous quantitation of prednisolone and dipyridamole in human plasma and its application in a pharmacokinetic study.
J Pharm Biomed Anal
; 49(5): 1241-9, 2009 Jul 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-19304431
9.
Ocular pharmacokinetics of besifloxacin following topical administration to rabbits, monkeys, and humans.
J Ocul Pharmacol Ther
; 25(4): 335-44, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19492955
10.
4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine.
J Pharmacol Exp Ther
; 301(3): 1025-32, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12023534
11.
The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine.
J Pharmacol Exp Ther
; 304(2): 539-46, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12538805
12.
Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam.
Drug Metab Dispos
; 31(5): 548-58, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12695342
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