Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 34
Filtrar
Más filtros

Banco de datos
País/Región como asunto
Tipo del documento
País de afiliación
Intervalo de año de publicación
1.
Surg Endosc ; 32(1): 252-259, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28664438

RESUMEN

BACKGROUND AND AIMS: Many patients who undergo bariatric surgery will experience weight regain and effective strategies are needed to help these patients. A dilated gastrojejunal anastomosis (GJA) has been associated with weight recidivism after Roux-en-Y gastric bypass surgery (RYGB). Endoscopic transoral outlet reduction (TORe) with a full thickness endoscopic suturing device (Overstitch, Apollo Endosurgery, Austin, TX) is a minimally invasive therapeutic option. The primary aim of this project was to examine the safety and long-term efficacy data from three bariatric surgery centers and to conduct a systematic review and meta-analysis of the existing literature. METHODS: Patients who underwent TORe with the Overstitch device from Jan 2013 to Nov 2016 at 3 participating bariatric surgery centers were included in the multicenter analysis. For the systematic review and meta-analysis, a comprehensive search of multiple English databases was conducted. Random effects model was used. RESULTS: 130 consecutive patients across three centers underwent TORe with an endolumenal suturing device. These patients (mean age 47; mean BMI 36.8) had experienced 24.6% weight regain from nadir weight after RYGB. Average weight lost at 6, 12, and 18 months after TORe was 9.31 ± 6.7 kg (N = 84), 7.75 ± 8.4  kg (N = 70), 8 ± 8.8 kg (N = 46) (p < 0.01 for all three time points), respectively. The meta-analysis included 330 patients. The pooled weight lost at 12 months was 8.4 kg (95% CI 6.5-10.3) with no significant heterogeneity across included studies (p = 0.07). Overall, 14% of patients experienced nausea, 18% had pain and 8% required a repeat EGD. No serious adverse events reported. CONCLUSION: When implemented as part of a multidisciplinary intervention, TORe using endolumenal suturing is safe, reproducible, and effective approach to manage weight recidivism after RYGB and should be utilized early in the management algorithm of these patients.


Asunto(s)
Endoscopía/métodos , Derivación Gástrica , Obesidad Mórbida/cirugía , Reoperación/métodos , Técnicas de Sutura , Aumento de Peso , Adulto , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Recurrencia , Estudios Retrospectivos , Resultado del Tratamiento
2.
Eat Weight Disord ; 23(1): 87-94, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-27473870

RESUMEN

PURPOSE: To elicit patient experiences of weight management discussions with providers and provide recommendations for future weight-related discussions. METHODS: 1000 patients who recently saw their provider for non-weight specific appointments were mailed measures of demographics, self-reported height and weight, activity level, adherence, perceptions of and recommendations for weight-related discussions, and internalized weight bias. This study was primarily descriptive and utilized a mixed method design including collection of quantitative and qualitative data. RESULTS: 242 patients responded (24 % response rate); 32.4 % overweight (N = 72), 41.9 % obese (N = 93). 47 % of overweight and 71 % of obese patients recalled that their provider discussed weight; 92 % were motivated to follow recommendations and 89 % felt confident doing so. Most patients (75 %) would like their provider to be "very direct/straightforward" when discussing weight, and 52 % would be "not at all offended" if they were diagnosed as "overweight/obese." Most patients (63 %) reported being "extremely comfortable" discussing weight with providers. Patients with higher BMI had higher levels of internalized weight bias (p < .001) and wanted their provider to "discuss weight sensitively" (p < .05). CONCLUSION: This study suggests that patients have important preferences that providers should be mindful of when discussing weight. While these discussions can be challenging, most patients report that they would be comfortable having these conversations directly and most would have enhanced motivation and confidence following these conversations. Communicating about weight is needed and desired by patients; doing so sensitively with those at higher weight is essential.


Asunto(s)
Peso Corporal/fisiología , Motivación , Obesidad/terapia , Sobrepeso/terapia , Prioridad del Paciente , Relaciones Médico-Paciente , Anciano , Anciano de 80 o más Años , Comunicación , Femenino , Personal de Salud , Humanos , Masculino , Persona de Mediana Edad
3.
J Nutr ; 145(9): 2046-51, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26246321

RESUMEN

BACKGROUND: Caloric restriction alone has been shown to improve insulin action and fasting glucose metabolism; however, the mechanism by which this occurs remains uncertain. OBJECTIVE: We sought to quantify the effect of caloric restriction on ß cell function and glucose metabolism in people with type 2 diabetes. METHODS: Nine subjects (2 men, 7 women) with type 2 diabetes [BMI (in kg/m(2)): 40.6 ± 1.4; age: 58 ± 3 y; glycated hemoglobin: 6.9% ± 0.2%] were studied using a triple-tracer mixed meal after withdrawal of oral diabetes therapy. The oral minimal model was used to measure ß cell function. Caloric restriction limited subjects to a pureed diet (<900 kcal/d) for the 12 wk of study. The studies were repeated after 6 and 12 wk of caloric restriction. RESULTS: Fasting glucose concentrations decreased significantly from baseline after 6 wk of caloric restriction with no further reduction after a further 6 wk of caloric restriction (9.8 ± 1.3, 5.9 ± 0.2, and 6.2 ± 0.3 mmol/L at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.01) because of decreased fasting endogenous glucose production (EGP: 20.4 ± 1.1, 16.2 ± 0.8, and 17.4 ± 1.1 µmol · kg(-1) · min(-1) at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.03). These changes were accompanied by an improvement in ß cell function measured by the disposition index (189 ± 51, 436 ± 68, and 449 ± 67 10(-14) dL · kg(-1) · min(-2) · pmol(-1) at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.01). CONCLUSIONS: Six weeks of caloric restriction lowers fasting glucose and EGP with accompanying improvements in ß cell function in people with type 2 diabetes. An additional 6 wk of caloric restriction maintained the improvement in glucose metabolism. This trial was registered at clinicaltrials.gov as NCT01094054.


Asunto(s)
Glucemia/metabolismo , Restricción Calórica , Diabetes Mellitus Tipo 2/dietoterapia , Células Secretoras de Insulina/metabolismo , Periodo Posprandial , Índice de Masa Corporal , Péptido C/sangre , Ingestión de Energía , Ayuno , Femenino , Glucagón/sangre , Hemoglobina Glucada/metabolismo , Humanos , Insulina/sangre , Masculino , Persona de Mediana Edad , Factores de Tiempo
4.
Women Health ; 53(4): 405-18, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23751093

RESUMEN

UNLABELLED: Obesity rates have risen sharply in the United States, with minority women among those most affected. Although a majority of Americans are considered inactive, little attention has been devoted to studying the correlation of sedentary behavior with dietary cravings in adults. OBJECTIVE: The current study used objective and self-report methods to measure sedentary behavior and its relationship to food cravings in a sample of overweight African American and Caucasian women. DESIGN: Thirty-nine adult women (54% African American) with an average body mass index of 33.7 wore accelerometers for one week and completed self-report measures of sedentary behavior, physical activity, and food cravings. RESULTS: Self-reported television viewing time was slightly longer (3.0 versus 2.5 hours), although total sedentary time was shorter (6.7 versus 8.0 hours) on weekends versus weekdays. Weekend but not weekday sedentary time and television viewing were associated with stable aspects of food cravings rather than craving for specific foods. CONCLUSION: In this small sample, only a third of all sedentary time was attributed to viewing television. Assessing whether sedentary behavior occurs by necessity versus choice may be a factor to consider in examining its relationship to food cravings.


Asunto(s)
Negro o Afroamericano/psicología , Conducta Alimentaria/psicología , Conductas Relacionadas con la Salud/etnología , Sobrepeso/etnología , Conducta Sedentaria/etnología , Población Blanca/psicología , Acelerometría , Adulto , Negro o Afroamericano/estadística & datos numéricos , Anciano , Índice de Masa Corporal , Ejercicio Físico , Conducta Alimentaria/etnología , Femenino , Humanos , Persona de Mediana Edad , Proyectos Piloto , Factores de Riesgo , Autoinforme , Factores Socioeconómicos , Encuestas y Cuestionarios , Televisión/estadística & datos numéricos , Estados Unidos/epidemiología , Población Blanca/estadística & datos numéricos
5.
Am J Addict ; 21(4): 335-42, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22691012

RESUMEN

Current efforts underway to develop the fifth edition of the Diagnostic and Statistical Manual (DSM-5) have reignited discussions for classifying the substance use disorders. This study's aim was to contribute to the understanding of abusive alcohol use and its validity as a diagnosis. Cluster analysis was used to identify relatively homogeneous groups of hazardous, nondependent drinkers by using data collected from the Prevention and Treatment of Hypertension Study (PATHS), a multisite trial that examined the ability of a cognitive-behavioral-based alcohol reduction intervention, compared to a control condition, to reduce alcohol use. Participants for this study (N = 511) were male military veterans. Variables theoretically associated with alcohol use (eg, demographic, tobacco use, and mental health) were used to create the clusters and a priori, empirically based external criteria were used to assess discriminant validity. Bivariate correlations among cluster variables were generally consistent with previous findings in the literature. Analyses of internal and discriminant validity of the identified clusters were largely nonsignificant, suggesting meaningful differences between clusters could not be identified. Although the typology literature has contributed supportive validity for the alcohol dependence diagnosis, this study's results do not lend supportive validity for the construct of alcohol abuse.


Asunto(s)
Consumo de Bebidas Alcohólicas/psicología , Alcoholismo/diagnóstico , Alcoholismo/psicología , Adaptación Psicológica , Anciano , Bebidas , Cafeína , Análisis por Conglomerados , Depresión , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Humanos , Masculino , Persona de Mediana Edad , Motivación , Reproducibilidad de los Resultados , Fumar , Apoyo Social , Factores Socioeconómicos , Estrés Psicológico , Veteranos
6.
Surg Obes Relat Dis ; 17(4): 701-710, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33551252

RESUMEN

BACKGROUND: Cannabis is second only to alcohol as a substance of abuse and dependence in the United States. While there is extensive research examining alcohol use and bariatric surgery, there is currently little research and there are no published guidelines specific to cannabis use and bariatric surgery. OBJECTIVES: To identify major themes and general guidelines applied by bariatric surgery psychology clinicians. SETTING: This practice survey was disseminated to bariatric surgery psychologists at various U.S. academic medical centers, hospitals, and private practices. METHODS: An electronic, 35-question survey was sent to 47 bariatric surgery psychologists to collect information on current clinical practice guidelines regarding cannabis use before and after bariatric surgery. RESULTS: The survey questionnaire was completed by 34 (72.34%) bariatric surgery psychologists. The major identified themes included: (1) the lack of a standardized assessment of cannabis use; (2) a requirement for 3 months of abstinence from cannabis before bariatric surgery; (3) recommended lifetime abstinence from cannabis after bariatric surgery; and (4) discussion of cannabis use risks following bariatric surgery, including appetite stimulation, addiction potential, and possible negative impacts on judgment. CONCLUSION: Cannabis use will likely further increase in the United States. This survey highlighted common bariatric surgery psychology practices in the absence of extensive research and published guidelines. These findings suggest a preliminary framework with which to address cannabis use in patients seeking bariatric surgery. It is recommended that professional organizations and societies build on these initial survey findings to develop guidelines for more consistent, evidence-based practice regarding cannabis use and bariatric surgery.


Asunto(s)
Cirugía Bariátrica , Cannabis , Consumo de Bebidas Alcohólicas , Humanos , Práctica Psicológica , Encuestas y Cuestionarios , Estados Unidos
7.
Mayo Clin Proc ; 95(3): 527-540, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-32138881

RESUMEN

The prevalence of class 3 obesity (body mass index ≥40 kg/m2) is 7.7% of the United States adult population; thus, more than 25 million people may be medically appropriate for consideration of bariatric surgery as therapy for severe obesity. Although bariatric surgery is the most effective therapy for patients with severe obesity, the surgery is performed in less than 1% of patients annually for whom it may be appropriate. Patients' and medical professionals' misperceptions about obesity and bariatric surgery create barriers to accessing bariatric surgery that are not given adequate attention and clinical consideration. Commonly cited patient barriers are lack of knowledge about the severity of obesity, the perception that obesity is a lifestyle problem rather than a chronic disease, and fear that bariatric surgery is dangerous. Medical professional barriers include failing to recognize causes of obesity and weight gain, providing recommendations that are inconsistent with current obesity treatment guidelines, and being uncomfortable counseling patients about treatment options for severe obesity. Previous research has revealed that medical professional counseling and accurate perception of the health risks associated with severe obesity are strong predictors of patients' willingness to consider bariatric surgery. This article reviews patient and medical professional barriers to acceptance of bariatric surgery as a treatment of medical necessity and offers practical advice for medical professionals to rethink perspectives about bariatric surgery when it is medically and psychologically appropriate.


Asunto(s)
Cirugía Bariátrica/normas , Obesidad Mórbida/cirugía , Selección de Paciente , Actitud del Personal de Salud , Toma de Decisiones , Humanos , Obesidad Mórbida/epidemiología , Obesidad Mórbida/psicología , Estados Unidos/epidemiología
8.
Ethn Dis ; 19(2): 192-8, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19537232

RESUMEN

OBJECTIVE: A fifth subscale was recently added to the widely used multidimensional health locus of control (MHLC) measure, and little is known about the factor structure of the MHLC with the new scale among African Americans from disadvantaged backgrounds. Also, few studies have examined differences in Health Locus of Control (HLOC) beliefs across medical patients from similar demographic backgrounds. METHODS: We asked participants to complete a survey about HLOC beliefs and extracted biological markers from their medical charts. Participants were drawn from patients of internal medicine and infectious disease clinics at a charity hospital in Baton Rouge, Louisiana. In total, we surveyed 186 African American patients who were diagnosed with HIV/AIDS or type 2 diabetes. RESULTS: Confirmatory factor analysis could not confirm a 5-factor structure; however, a new 3-factor structure was produced that includes 1) internal health beliefs, 2) external health beliefs, and 3) God health beliefs. Patients with HIV/AIDS reported more external and God HLOC beliefs than did patients with type 2 diabetes. CONCLUSIONS: The factor structures that emerged from previous research may not be appropriate to use when conducting research with individuals from a low SES who are also from an ethnic/racial minority background. Our findings suggest a new 3-factor structure for the MHLC. Future research should examine whether patients with HIV/AIDS may benefit from interventions that target external beliefs to improve health behavior.


Asunto(s)
Actitud Frente a la Salud/etnología , Negro o Afroamericano/psicología , Diabetes Mellitus/psicología , Infecciones por VIH/psicología , Control Interno-Externo , Pruebas de Personalidad , Adulto , Enfermedad Crónica , Estudios de Cohortes , Diabetes Mellitus/etnología , Femenino , Infecciones por VIH/etnología , Humanos , Masculino , Persona de Mediana Edad , Religión , Reproducibilidad de los Resultados , Factores Socioeconómicos
9.
Eat Behav ; 34: 101310, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-31374335

RESUMEN

This study developed and provided initial validation for the Support for Healthy Lifestyle (SHeL), a set of scales designed to measure adolescent-perceived social support of healthy eating and physical activity. Item pool development utilized a prior focus group study of adolescents' perceptions of socially supportive behavior and a review of the literature on social support for health behavior change in adolescents. Exploratory factor analysis of the item pool completed by 220 adolescents, internal consistency estimates, and expert review of items and consensus resulted in 9 scales for the SHeL: Family Healthy Eating Support, Family Physical Activity Support, Family Hypocritical Control, Peer Health Eating Support, Peer Physical Activity Support, Peer Undermining, Professional Healthy Eating Support, Professional Physical Activity Support, and Professional General Support. Scale internal reliability estimates were α = 0.73-0.96. Supporting construct validity, the SHeL showed a pattern of stronger correlations between measures of the same source (parent/peer) and target behavior (healthy eating/physical activity) and stronger correlations with corresponding Sallis scales vis-à-vis other Sallis scales, with exceptions related to peer support for healthy eating. Divergent validity was somewhat limited, including in two instances, the SHeL scale was more strongly correlated with another SHeL scale. Supporting criterion validity, often the SHeL scales were correlated with related health behaviors. This study provided important psychometric information for a new measurement of social support for health behavior for adolescents. Further research with larger, more diverse, and treatment-seeking populations is needed to provide further validation of the SHeL and to begin to establish normative scores.


Asunto(s)
Dieta Saludable/psicología , Ejercicio Físico/psicología , Conducta Alimentaria/psicología , Conductas Relacionadas con la Salud , Psicometría/métodos , Apoyo Social , Adolescente , Análisis Factorial , Femenino , Grupos Focales , Humanos , Masculino , Grupo Paritario , Reproducibilidad de los Resultados , Conducta Social , Encuestas y Cuestionarios
10.
J Clin Psychol Med Settings ; 15(2): 163-9, 2008 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19104981

RESUMEN

The current study examined social support and stress as mediators of the hostility-coronary heart disease (CHD) relationship as suggested by the psychosocial vulnerability model in a sample of low-income African Americans. Among 95 CHD patients and 30 healthy controls, hostility was negatively correlated with social support, but was not related to minor stress. CHD patients endorsed higher levels of hostility; however, the relationship between hostility and CHD status was diminished once stress and social support were included in the model. This study lends partial support for the psychosocial vulnerability model of hostility in African Americans, but suggests that the relationship between hostility and stress may be impacted by socioeconomic status.


Asunto(s)
Negro o Afroamericano/psicología , Enfermedad Coronaria/psicología , Hostilidad , Modelos Psicológicos , Pobreza/psicología , Negro o Afroamericano/estadística & datos numéricos , Comorbilidad , Enfermedad Coronaria/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Oportunidad Relativa , Pobreza/estadística & datos numéricos , Valor Predictivo de las Pruebas , Psicometría/métodos , Psicometría/estadística & datos numéricos , Índice de Severidad de la Enfermedad , Apoyo Social , Factores Socioeconómicos , Estrés Psicológico/epidemiología , Estrés Psicológico/psicología , Encuestas y Cuestionarios , Estados Unidos/epidemiología
11.
Ethn Dis ; 17(2 Suppl 2): S2-55-9, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17684816

RESUMEN

Cardiovascular diseases account for a significant portion of deaths and healthcare costs in the United States. Women from ethnic minorities and rural areas carry a disproportionately higher burden of cardiovascular morbidity and mortality. Many factors contribute to this persistent disparity: a comparatively low level of awareness especially among the at-risk populations, increased prevalence of cardiovascular risks linked to the obesity epidemic, and inconsistent levels of screening and treatment of cardiovascular risks. Cultural and social factors that influence lifestyle and behavior also have significant cardiovascular health consequences and contribute to the disparity. Any intervention to address health disparities should include a community-based component that incorporates education at the lay level, as well as the healthcare provider level. We describe a community education initiative to increase awareness and knowledge about heart disease in women and a community-academic collaborative project to improve diabetes and cardiovascular outcome. These programs have been successfully initiated in the Mississippi Delta, a location with some of the highest cardiovascular mortality (especially among the African American women) as well as limited healthcare infrastructure, low socioeconomic levels, and low literacy rates.


Asunto(s)
Enfermedades Cardiovasculares/etiología , Redes Comunitarias , Educación en Salud , Negro o Afroamericano , Enfermedades Cardiovasculares/epidemiología , Enfermedades Cardiovasculares/etnología , Enfermedades Cardiovasculares/mortalidad , Femenino , Humanos , Masculino , Mississippi/epidemiología , Factores de Riesgo , Población Blanca
12.
J Assoc Nurses AIDS Care ; 18(3): 65-73, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17570301

RESUMEN

Patients with HIV/AIDS are likely to have numerous interactions with health care providers (HCPs) during the course of their disease. Research has shown that satisfaction with one's HCP is related to better medication adherence in patients with HIV/AIDS. Although a patient's attitude toward his or her HCP is important, little has been done to assess how it relates to appointment attendance. The current study assessed how attitudes toward HCPs as well as social support and depression relate to outpatient appointment attendance. Further, this study used a newly developed, psychometrically valid scale to assess specific patient attitudes toward HCPs including those related to disease stigma. Participants were predominantly low-income African American men (N = 109) recruited from a public southern HIV clinic. Analyses indicated that attitudes toward HIV HCPs, social support, and medication status but not depression or satisfaction with social support were associated with appointment attendance.


Asunto(s)
Citas y Horarios , Infecciones por VIH/terapia , Aceptación de la Atención de Salud/psicología , Relaciones Profesional-Paciente , Adulto , Terapia Antirretroviral Altamente Activa , Depresión/psicología , Femenino , Infecciones por VIH/tratamiento farmacológico , Infecciones por VIH/psicología , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Análisis de Regresión , Apoyo Social , Estados Unidos
13.
Surg Obes Relat Dis ; 13(8): 1369-1375, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28600115

RESUMEN

BACKGROUND: Support following bariatric surgery is vital to ensure long-term postoperative success. Many individuals undergoing bariatric surgery are turning to online modalities, especially the popular social media platform Facebook, to access support groups and pages. Despite evidence suggesting that the majority of patients considering bariatric surgery are utilizing online groups, little is known about the actual content of these groups. OBJECTIVES: The purpose of the present study was to conduct a content analysis of bariatric surgery support groups and pages on Facebook. SETTING: Online via Facebook, independent academic medical center, United States. METHODS: Data from bariatric surgery-related Facebook support groups and pages were extracted over a 1-month period in 2016. Salient content themes (e.g., progress posts, depression content, eating behaviors) were coded reliably (all κ> .70). RESULTS: More than 6,800 posts and replies were coded. Results indicated that seeking recommendations (11%), providing information or recommendations (53%), commenting on changes since surgery (19%), and lending support to other members (32%) were the most common types of posts. Content surrounding anxiety, eating behaviors, depression, body image, weight bias, and alcohol was found less frequently. CONCLUSIONS: Online bariatric surgery groups can be used to receive support, celebrate physical and emotional accomplishments, provide anecdotal accounts of the "bariatric lifestyle" for preoperative patients, and comment on challenges with mental health and experiences of weight bias. Providers should become acquainted with the content commonly found in online groups and exercise caution in recommending these platforms to information-seeking patients.


Asunto(s)
Cirugía Bariátrica , Obesidad Mórbida/cirugía , Grupos de Autoayuda/estadística & datos numéricos , Medios de Comunicación Sociales/estadística & datos numéricos , Apoyo Social , Consumo de Bebidas Alcohólicas/psicología , Ansiedad/psicología , Imagen Corporal , Depresión/psicología , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Humanos , Salud Mental , Obesidad Mórbida/psicología
14.
Obes Surg ; 27(10): 2759-2767, 2017 10.
Artículo en Inglés | MEDLINE | ID: mdl-28815388

RESUMEN

BACKGROUND: Helping patients determine which type of bariatric surgery, Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG), may be the best treatment can be challenging. This study investigated psychological correlates and their influence on weight loss for patients who underwent RYGB or VSG. METHODS: Four hundred twenty-two patients (RYGB = 305; VSG = 117) completed screening questionnaires presurgery and underwent surgery between August 2012 and April 2015. Associations between demographics and questionnaires with percentage weight change were evaluated using multivariable linear regression models. RESULTS: Median age was 48 years and median BMI 45.3 kg/m2 presurgery. Median percentage changes in weight from baseline to years 1 and 2 follow-up were - 31.5% (range - 52.2 to - 9.2%) and - 31.2% (range - 50.0 to - 1.2%) for RYGB and 25.3% (range - 49.8 to - 4.7%) and - 23.3% (range - 58.9 to - 1.6%) for VSG, respectively. Linear regression models revealed that younger patients lost more weight than older patients at years 1 (RYGB p < 0.0001; VSG p = 0.0001) and 2 (RYGB p = 0.005; VSG p = 0.002). No psychological correlates were significantly associated with weight loss outcomes. Post hoc analyses comparing patients who had surgery to those in the same cohort who did not have surgery revealed significantly higher rates of depression (p < 0.001), anxiety (p < 0.001), binge eating (p = 0.003), night eating (p < 0.001), food addiction (p = 0.042), and lower self-efficacy (p < 0.001) among patients who did not have surgery. DISCUSSION: Patients who are psychologically higher functioning are more likely to complete the evaluation process and undergo bariatric surgery. For patients who had surgery, psychological correlates were not associated with weight loss outcome for either RYGB or VSG. Implications for surgical choice are discussed.


Asunto(s)
Cirugía Bariátrica/métodos , Conducta de Elección , Toma de Decisiones , Obesidad Mórbida/psicología , Obesidad Mórbida/cirugía , Adulto , Afecto/fisiología , Cirugía Bariátrica/efectos adversos , Cirugía Bariátrica/psicología , Estudios de Cohortes , Ingestión de Alimentos/psicología , Femenino , Gastrectomía/métodos , Gastrectomía/psicología , Derivación Gástrica/métodos , Derivación Gástrica/psicología , Conductas Relacionadas con la Salud/fisiología , Humanos , Masculino , Persona de Mediana Edad , Pérdida de Peso/fisiología
15.
Pharmacotherapy ; 37(11): 1374-1382, 2017 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-28845898

RESUMEN

STUDY OBJECTIVE: The extended-release (ER) form of venlafaxine is preferred because of improved patient adherence, but the immediate-release (IR) form is frequently used after Roux-en-Y gastric bypass (RYGB) surgery because of concerns for malabsorption. The objective of this study was to determine whether a statistically significant and predictable change in the bioavailability of venlafaxine ER capsules occurs after RYGB. DESIGN: Prospective nonblinded single-dose pharmacokinetic study. SETTING: Clinical research unit at a large tertiary care medical practice. PATIENTS: Ten adult pre-bariatric surgery patients who met the criteria for noncomplicated RYGB were enrolled and served as their own controls. INTERVENTIONS: Patients were administered one venlafaxine ER 75-mg capsule at two visits-the first visit at least 1 week before undergoing RYGB and the second visit 3-4 months after RYGB. Blood samples were collected at predetermined intervals over 48 hours after each dose, and the pharmacokinetics of venlafaxine were measured. MEASUREMENTS AND MAIN RESULTS: Plasma levels of venlafaxine and its primary metabolite, O-desmethylvenlafaxine (ODV), were compared at baseline and 3-4 months after RYGB. The areas under the serum concentration-time curves from 0-24 hours (AUC0-24 ) for venlafaxine (mean ± SD 734 ± 602 vs 630 ± 553 ng·hr/ml, p=0.22) and ODV (mean ± SD 894 ± 899 vs 1083 ± 972 ng·hr/ml, p=0.07) were similar before and after RYGB. Using a bioequivalence approach, differences in pre-RYGB and post-RYGB values of AUC0-24 , peak serum concentration, and time to peak serum concentration were not statistically significant for either venlafaxine or ODV. CONCLUSION: This study suggests that RYGB does not significantly alter the amount of venlafaxine or its active metabolite, ODV, absorbed from a venlafaxine ER capsule or the time over which it is absorbed.


Asunto(s)
Derivación Gástrica/métodos , Obesidad/cirugía , Inhibidores de Captación de Serotonina y Norepinefrina/administración & dosificación , Clorhidrato de Venlafaxina/administración & dosificación , Adulto , Anciano , Área Bajo la Curva , Disponibilidad Biológica , Cápsulas , Preparaciones de Acción Retardada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Inhibidores de Captación de Serotonina y Norepinefrina/farmacocinética , Equivalencia Terapéutica , Factores de Tiempo , Clorhidrato de Venlafaxina/farmacocinética
16.
Am J Med Sci ; 331(4): 201-6, 2006 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-16617235

RESUMEN

Psychological evaluation of the weight loss surgery patient is recommended because of the prevalence of psychiatric comorbidities in persons with severe obesity and the behavioral adaptations required for successful surgical outcomes. Although there is currently no national standard for the specific components of these evaluations, there is general agreement in the literature about the objectives and the kinds of assessment methods that are most useful. This paper summarizes the current literature on psychological evaluation of weight loss surgery patients. Methods of assessment relevant to the major behavioral health characteristics of surgical candidates are reviewed, and results from several studies examining weight loss and quality of life outcomes in relation to pre-surgery psychological characteristics are discussed.


Asunto(s)
Cirugía Bariátrica/psicología , Obesidad Mórbida/psicología , Obesidad Mórbida/cirugía , Obesidad/psicología , Obesidad/cirugía , Comorbilidad , Contraindicaciones , Humanos , Trastornos Mentales/epidemiología , Obesidad/epidemiología , Obesidad/fisiopatología , Evaluación de Resultado en la Atención de Salud , Manejo de Atención al Paciente , Calidad de Vida , Grupos de Autoayuda , Resultado del Tratamiento , Pérdida de Peso
17.
Obes Surg ; 26(6): 1274-8, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26341087

RESUMEN

BACKGROUND: Screening for depressive symptoms is important when evaluating bariatric surgery candidates, as worse outcomes can be seen with higher pre-surgical and post-surgical psychiatric comorbidities. The Beck Depression Inventory-II (BDI-II) and Patient Health Questionnaire (PHQ-9) are two widely used depression screening instruments. This study evaluated whether both instruments have similar performance in an outpatient bariatric surgery clinic setting. METHODS: One thousand thirty-four bariatric surgery candidates completed both PHQ-9 and BDI-II whose scores were analyzed in this retrospective study. Spearman's correlation coefficient was calculated to compare total scores on each instrument. PHQ-9 categories were compared to corresponding BDI-II categories via several different methods. Weighted kappa coefficients were calculated for (1) PHQ-9 and BDI-II categories, (2) scores ≥10 on the PHQ-9 and ≥20 on the BDI-II, and (3) the specific item of suicidality. RESULTS: Spearman's correlation was strong at 0.74. The median PHQ-9 and BDI-II scores were 5 and 9, corresponding to the mild and minimal categories, respectively. Weighted kappa analysis demonstrated a moderate association between depressive symptom categories evaluated using three methods. A moderate to substantial association was found for the suicidality item, with agreement of 92.3 %. CONCLUSIONS: PHQ-9 and BDI-II scores in patients seeking bariatric surgery are closely correlated. Categories of depressive symptom severity and responses to suicidality showed moderate to substantial agreement. When choosing an appropriate depression screening tool, these findings support the use of the PHQ-9 as a viable alternative to the BDI-II in patients seeking bariatric surgery.


Asunto(s)
Cirugía Bariátrica/psicología , Depresión/diagnóstico , Obesidad Mórbida/cirugía , Escalas de Valoración Psiquiátrica , Adulto , Anciano , Comorbilidad , Trastorno Depresivo/diagnóstico , Femenino , Humanos , Masculino , Tamizaje Masivo/métodos , Persona de Mediana Edad , Obesidad Mórbida/psicología , Servicio Ambulatorio en Hospital , Cuestionario de Salud del Paciente , Reproducibilidad de los Resultados , Estudios Retrospectivos , Ideación Suicida
18.
Obes Surg ; 26(7): 1559-64, 2016 07.
Artículo en Inglés | MEDLINE | ID: mdl-26464243

RESUMEN

INTRODUCTION/PURPOSE: Distress intolerance is characterized by a low threshold for negative emotional experiences and lack of emotion regulation and has been shown to predict various health outcomes. As such, the primary aim of this study was to determine the association between distress tolerance and psychological variables (eating behaviors, mood, substance use, trauma history), completion of bariatric surgery, and post-bariatric surgery weight loss outcomes and follow up with a provider. MATERIALS AND METHODS: Two hundred forty-eight patients (75 % female, 89 % Caucasian) underwent a multidisciplinary evaluation for bariatric surgery and were assessed for psychiatric disorders via semi-structured clinical interview and psychometric questionnaires. RESULTS: Low distress tolerance was associated with symptoms of depression (p ≤ 0.001), anxiety (p ≤ 0.001), disordered eating behaviors (p ≤ 0.001), substance abuse (p ≤ 0.001), a history of being the victim of childhood sexual abuse (p ≤ 0.001), and with high BMI (p < .05). Patients endorsing higher levels of distress tolerance were more likely to undergo bariatric surgery (p < .01). Distress tolerance was not related to 2-year post-surgical weight loss outcomes or follow up with a provider. CONCLUSION: The ability to tolerate negative affect may be a variable that differentiates which patients undergo bariatric surgery rather than early postoperative outcomes.


Asunto(s)
Cirugía Bariátrica/psicología , Ajuste Emocional , Trastornos Mentales/psicología , Obesidad/psicología , Obesidad/cirugía , Adaptación Psicológica , Adulto , Comorbilidad , Emociones , Femenino , Humanos , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Encuestas y Cuestionarios , Pérdida de Peso
19.
Surg Obes Relat Dis ; 12(1): 165-70, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26183302

RESUMEN

BACKGROUND: Food addiction (FA) may be related to poor weight loss outcomes; however, the literature on food addiction in bariatric surgery-seeking populations is limited. OBJECTIVES: The aim of the present study was to identify the prevalence of FA in a bariatric surgery-seeking population and its association with mood, problematic eating behaviors, and substance use. The relationship between prebariatric surgery food addiction screening and postsurgical outcomes was assessed. SETTING: Academic medical center. METHODS: Adult outpatients (n = 923) seeking bariatric surgery underwent psychological evaluation between January 2012 and May 2014. Patients were administered the Yale Food Addiction Scale (YFAS) to assess FA. Of the original sample, 195 patients underwent Roux-en-Y gastric bypass surgery. Patients returned for medical follow-up at 6 (n = 169) and 12 (n = 113) months postsurgery; 26 (13%) patients at 6 months and 82 (42%) patients at 12 months were lost to follow-up or had not reached 1 year postsurgery. RESULTS: Fourteen percent of patients met FA criteria. Patients positive for FA were more likely to endorse greater levels of depression, anxiety, binge eating episodes, nighttime eating syndrome, and low eating self-efficacy. No relationship was observed between FA and current substance use. FA did not predict postoperative outcomes including weight loss, rehospitalization, or attendance at follow-up medical appointments. CONCLUSIONS: FA is related to psychological distress and eating disordered behaviors among bariatric patients. However, FA was not predictive of short-term (6-12 mo) bariatric surgery outcomes. Future research should determine how FA affects long-term postoperative outcomes and mood stability.


Asunto(s)
Afecto , Cirugía Bariátrica/psicología , Conducta Adictiva/complicaciones , Trastorno por Atracón/complicaciones , Depresión/complicaciones , Conducta Alimentaria/psicología , Obesidad Mórbida/cirugía , Adolescente , Adulto , Anciano , Conducta Adictiva/epidemiología , Conducta Adictiva/psicología , Trastorno por Atracón/epidemiología , Trastorno por Atracón/psicología , Depresión/epidemiología , Depresión/psicología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Obesidad Mórbida/complicaciones , Obesidad Mórbida/psicología , Prevalencia , Pronóstico , Estudios Retrospectivos , Encuestas y Cuestionarios , Factores de Tiempo , Pérdida de Peso/fisiología , Adulto Joven
20.
Psychol Assess ; 17(1): 110-4, 2005 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15769232

RESUMEN

The psychometric properties of the Beck Depression Inventory-II (BDI-II) are well established with primarily Caucasian samples. However, little is known about its reliability and validity with minority groups. This study evaluated the psychometric properties of the BDI-II in a sample of low-income African American medical outpatients (N=220). Reliability was demonstrated with high internal consistency (.90) and good item-total intercorrelations. Criterion-related validity was demonstrated. A confirmatory factor analysis supported a hierarchical factor structure in which the BDI-II reflected 2 first-order factors (Cognitive and Somatic) that in turn reflected a second-order factor (Depression). These results are consistent with previous findings and thus support the use of the BDI-II in assessing depressive symptoms for African American patients in a medical setting.


Asunto(s)
Negro o Afroamericano/psicología , Trastorno Depresivo Mayor/diagnóstico , Trastorno Depresivo Mayor/etnología , Pruebas Psicológicas , Adulto , Anciano , Anciano de 80 o más Años , Demografía , Análisis Factorial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Factores Socioeconómicos , Encuestas y Cuestionarios
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA