Detalles de la búsqueda
1.
Investigation of selective retinoic acid receptor alpha antagonist ER-50891 and related analogs for male contraception.
Arch Pharm (Weinheim)
; 356(7): e2300031, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37154197
2.
Steroidal Antagonists of Progesterone- and Prostaglandin E1-Induced Activation of the Cation Channel of Sperm.
Mol Pharmacol
; 101(1): 56-67, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34718225
3.
FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer.
Biochemistry
; 60(18): 1413-1419, 2021 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32930576
4.
Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis.
Biol Reprod
; 103(2): 368-377, 2020 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32667031
5.
Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
Neurobiol Dis
; 116: 93-105, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29758256
6.
Recombinant production of enzymatically active male contraceptive drug target hTSSK2 - Localization of the TSKS domain phosphorylated by TSSK2.
Protein Expr Purif
; 121: 88-96, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26777341
7.
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.
J Med Chem
; 66(3): 1928-1940, 2023 02 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36701569
8.
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun
; 14(1): 3213, 2023 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37270540
9.
Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception.
Eur J Med Chem
; 261: 115821, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37776573
10.
Quantification of adverse events associated with functional MRI scanning and with real-time fMRI-based training.
Int J Behav Med
; 19(3): 372-81, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21633905
11.
Discovery and Characterization of Multiple Classes of Human CatSper Blockers.
ChemMedChem
; 17(15): e202000499, 2022 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35644882
12.
Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2.
ACS Chem Biol
; 15(7): 1759-1764, 2020 07 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32433863
13.
Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins.
ACS Chem Biol
; 15(11): 3038-3049, 2020 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33138352
14.
7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.
J Med Chem
; 62(14): 6824-6830, 2019 07 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31268316
15.
Automated Live-Cell Imaging of Synapses in Rat and Human Neuronal Cultures.
Front Cell Neurosci
; 13: 467, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31680875
16.
The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.
Open Biol
; 9(8): 190117, 2019 08 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31409229
17.
Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception.
J Med Chem
; 61(5): 1800-1820, 2018 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29291372
18.
Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe.
ACS Med Chem Lett
; 9(12): 1223-1229, 2018 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30613330
19.
Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinaseâ 2 (TSSK2).
ChemMedChem
; 12(22): 1857-1865, 2017 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28952188
20.
Corrigendum: Discovery and Characterization of Multiple Classes of Human CatSper Blockers.
ChemMedChem
; 17(19): e202200441, 2022 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36002337