Búsqueda | BVS CLAP/SMR-OPS/OMS

1.

Probing the mechanisms of two exonuclease domain mutators of DNA polymerase Ïµ.

Dahl, Joseph M; Thomas, Natalie; Tracy, Maxwell A; Hearn, Brady L; Perera, Lalith; Kennedy, Scott R; Herr, Alan J; Kunkel, Thomas A.

Nucleic Acids Res ; 50(2): 962-974, 2022 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-35037018

2.

Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.

Lee, Mitchell B; Dowsett, Ian T; Carr, Daniel T; Wasko, Brian M; Stanton, Sarah G; Chung, Michael S; Ghodsian, Niloufar; Bode, Anna; Kiflezghi, Michael G; Uppal, Priya A; Grayden, Katherine A; Elala, Yordanos C; Tang, Thao T; Tran, Ngoc H B; Tran, Thu H B; Diep, Anh B; Hope, Michael; Promislow, Daniel E L; Kennedy, Scott R; Kaeberlein, Matt; Herr, Alan J.

Proc Natl Acad Sci U S A ; 116(8): 3062-3071, 2019 02 19.

Artículo en Inglés | MEDLINE | ID: mdl-30718408

3.

Volatility of Mutator Phenotypes at Single Cell Resolution.

Kennedy, Scott R; Schultz, Eric M; Chappell, Thomas M; Kohrn, Brendan; Knowels, Gary M; Herr, Alan J.

PLoS Genet ; 11(4): e1005151, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25868109

4.

dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase Îµ variants.

Williams, Lindsey N; Marjavaara, Lisette; Knowels, Gary M; Schultz, Eric M; Fox, Edward J; Chabes, Andrei; Herr, Alan J.

Proc Natl Acad Sci U S A ; 112(19): E2457-66, 2015 May 12.

Artículo en Inglés | MEDLINE | ID: mdl-25827226

5.

POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome.

Lessel, Davor; Hisama, Fuki M; Szakszon, Katalin; Saha, Bidisha; Sanjuanelo, Alexander Barrios; Salbert, Bonnie A; Steele, Pamela D; Baldwin, Jennifer; Brown, W Ted; Piussan, Charles; Plauchu, Henri; Szilvássy, Judit; Horkay, Edit; Högel, Josef; Martin, George M; Herr, Alan J; Oshima, Junko; Kubisch, Christian.

Hum Mutat ; 36(11): 1070-9, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26172944

6.

Mutator suppression and escape from replication error-induced extinction in yeast.

Herr, Alan J; Ogawa, Masanori; Lawrence, Nicole A; Williams, Lindsey N; Eggington, Julie M; Singh, Mallika; Smith, Robert A; Preston, Bradley D.

PLoS Genet ; 7(10): e1002282, 2011 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22022273

7.

Antimutator variants of DNA polymerases.

Herr, Alan J; Williams, Lindsey N; Preston, Bradley D.

Crit Rev Biochem Mol Biol ; 46(6): 548-70, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21977975

8.

DNA replication fidelity and cancer.

Preston, Bradley D; Albertson, Tina M; Herr, Alan J.

Semin Cancer Biol ; 20(5): 281-93, 2010 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-20951805

9.

A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae.

Jiang, Pengyao; Ollodart, Anja R; Sudhesh, Vidha; Herr, Alan J; Dunham, Maitreya J; Harris, Kelley.

Elife ; 102021 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-34523420

10.

Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles.

Dowsett, Ian T; Sneeden, Jessica L; Olson, Branden J; McKay-Fleisch, Jill; McAuley, Emma; Kennedy, Scott R; Herr, Alan J.

Commun Biol ; 4(1): 21, 2021 01 04.

Artículo en Inglés | MEDLINE | ID: mdl-33398111

11.

Spontaneous Polyploids and Antimutators Compete During the Evolution of Saccharomyces cerevisiae Mutator Cells.

Tracy, Maxwell A; Lee, Mitchell B; Hearn, Brady L; Dowsett, Ian T; Thurber, Luke C; Loo, Jason; Loeb, Anisha M; Preston, Kent; Tuncel, Miles I; Ghodsian, Niloufar; Bode, Anna; Tang, Thao T; Chia, Andy R; Herr, Alan J.

Genetics ; 215(4): 959-974, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32513814

12.

Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae.

Chen, Kenneth L; Ven, Toby N; Crane, Matthew M; Brunner, Matthew L C; Pun, Adrian K; Helget, Kathleen L; Brower, Katherine; Chen, Dexter E; Doan, Ha; Dillard-Telm, Justin D; Huynh, Ellen; Feng, Yen-Chi; Yan, Zili; Golubeva, Alexandra; Hsu, Roy A; Knight, Raheem; Levin, Jessie; Mobasher, Vesal; Muir, Michael; Omokehinde, Victor; Screws, Corey; Tunali, Esin; Tran, Rachael K; Valdez, Luz; Yang, Edward; Kennedy, Scott R; Herr, Alan J; Kaeberlein, Matt; Wasko, Brian M.

Geroscience ; 42(2): 749-764, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31975050

13.

Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase Î´ variant.

Dennis, Daniel G; McKay-Fleisch, Jill; Eitzen, Kaila; Dowsett, Ian; Kennedy, Scott R; Herr, Alan J.

Sci Rep ; 7: 46535, 2017 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-28417960

14.

Pathways through the small RNA world of plants.

Herr, Alan J.

FEBS Lett ; 579(26): 5879-88, 2005 Oct 31.

Artículo en Inglés | MEDLINE | ID: mdl-16162339

15.

DNA replication error-induced extinction of diploid yeast.

Herr, Alan J; Kennedy, Scott R; Knowels, Gary M; Schultz, Eric M; Preston, Bradley D.

Genetics ; 196(3): 677-91, 2014 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-24388879

16.

Emergence of DNA polymerase Îµ antimutators that escape error-induced extinction in yeast.

Williams, Lindsey N; Herr, Alan J; Preston, Bradley D.

Genetics ; 193(3): 751-70, 2013 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-23307893

17.

Somatic mutations in aging, cancer and neurodegeneration.

Kennedy, Scott R; Loeb, Lawrence A; Herr, Alan J.

Mech Ageing Dev ; 133(4): 118-26, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22079405

18.

An SNF2 protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in Arabidopsis.

Smith, Lisa M; Pontes, Olga; Searle, Iain; Yelina, Nataliya; Yousafzai, Faridoon K; Herr, Alan J; Pikaard, Craig S; Baulcombe, David C.

Plant Cell ; 19(5): 1507-21, 2007 May.

Artículo en Inglés | MEDLINE | ID: mdl-17526749

19.

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.

Herr, Alan J; Molnàr, Attila; Jones, Alex; Baulcombe, David C.

Proc Natl Acad Sci U S A ; 103(41): 14994-5001, 2006 Oct 10.

Artículo en Inglés | MEDLINE | ID: mdl-17008405

20.

Factors that influence selection of coding resumption sites in translational bypassing: minimal conventional peptidyl-tRNA:mRNA pairing can suffice.

Herr, Alan J; Wills, Norma M; Nelson, Chad C; Gesteland, Raymond F; Atkins, John F.

J Biol Chem ; 279(12): 11081-7, 2004 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-14707145

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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