Round pneumonia in adults.

We recently evaluated three adult patients with rounded densities on their chest roentgenograms in whom the final diagnosis was presumed to be lower respiratory tract infection. In all cases, the circular infiltrates proved to be localized "round pneumonias." Round pneumonia has been well described in children but is less well known in adults. While uncommon, round pneumonia in adults may not be rare and deserves early diagnostic consideration to prevent unnecessary investigation.

Hospital admissions caused by iatrogenic disease.

Complications of medical therapy requiring hospitalization affect the costs and quality of medical care. We studied all admissions to the medical services of a public teaching hospital to characterize current incidence and cause of iatrogenic admissions. We studied 834 admissions resulting in 47 distinct iatrogenic events and 45 iatrogenic admissions (5.4%). Thirty-five cases were caused by medications, nine by procedures, one by radiotherapy, one by transfusional therapy, and one by nosocomial infection. Almost 50% of these admissions were avoidable. Though the incidence of iatrogenic admissions in this study is similar to that in previous reports, the profile of the responsible agents is different. We did not find relationships with age, number or type of diagnoses, or number of medications on admission. Study of other patient and physician characteristics may be more rewarding in reducing the number of iatrogenic complications.

The new medical practice environment. Internists' view of the future.

There have been many changes in the environment in which internal medicine is practiced in recent years. This has been coupled with reports of internists becoming frustrated and of internists leaving primary care practice. We conducted a survey of 219 internists in academic and private practice in western New York. While internists were generally positive regarding the training of residents, there was a pervasive feeling of frustration and demoralization among practicing internists. This demoralization may affect recruitment of new physicians to internal medicine and cause early retirement of practicing internists. The study demonstrated some of the causes of the demoralization.

Intravenous therapy team and peripheral venous catheter-associated complications. A prospective controlled study.

A prospective controlled trial was conducted on four similar inpatient medical wards to test the hypothesis that a trained intravenous therapy (IVT) team would substantially reduce the incidence of peripheral intravenous (IV) catheter-related complications. We followed 863 IV catheters. The overall incidence of phlebitis in the ward staff-maintained IV catheters was 32% as compared with 15% for those maintained by the IVT team. The incidence of two more serious complications (cellulitis and suppurative phlebitis) was reduced tenfold from 2.1% to 0.2%. We conclude that an IVT team can substantially reduce the iatrogenic complications related to IV catheters.

The natural history of intravenous catheter-associated phlebitis.

During a controlled evaluation of an intravenous therapy (IVT) team, we had the opportunity to follow up 202 episodes of catheter-associated phlebitis. While the IVT team had a considerable effect on the incidence of phlebitis, the clinical course of this complication was not influenced. More than 40% of catheter-associated phlebitis occurred more than 24 hours after withdrawal of the catheter. Premonitory symptoms were not useful in predicting the development of phlebitis. Factors that influenced the duration of phlebitis included the patient's diagnosis and the administration of vancomycin hydrochloride. The duration of phlebitis was prolonged by delayed removal of the catheter after the development of phlebitis.

Enhancing physician adoption of practice guidelines. Dissemination of influenza vaccination guideline using a small-group consensus process.

BACKGROUND: A dissemination intervention to facilitate adoption of a preventive practice guideline (influenza vaccination for older adults) in group practices was developed and evaluated. The intervention, small-group consensus process, started with a physician expert presenting the guideline and followed with the group participating in a structured discussion of ways to implement the guideline that culminated in a public commitment (ie, "buy in") to adopt the guideline. METHODS: Thirteen group practices and their primary care physicians (mean size, 5) were assigned randomly to intervention or control arms. In each group practice, physicians in the intervention arm met for 1 hour. Control physicians participated in an unrelated discussion (non-steroidal drug use). Guideline adoption was determined by changes in physicians' vaccination rates that were obtained through prechart and postchart reviews of 51 physicians. Prequestionnaires and postquestionnaires measured influenza knowledge and prevention attitudes. RESULTS: Using analysis of covariance, the small-group consensus process was found to increase physician vaccination rates by 34% compared with the control arm (F (1,48) = 19.49). All intervention arm physicians increased vaccination rates from before to after compared with 54% of control arm physicians. Attitudes and knowledge did not change and were unrelated to increased vaccination rates. CONCLUSIONS: A case is made for the small-group consensus process as an effective utilization-focused dissemination method. Interventions based on group dynamics and sensitive to local practice contexts can be useful in facilitating adoption of guidelines by physicians in group practices.

CSF silicon in dementia: a prospective study.

We designed a prospective study to determine whether CSF silicon elevation is specific for Alzheimer-type dementia (ATD) and whether it is related to the severity of cognitive or functional impairment. We found elevated CSF silicon in 30% of 23 ATD patients but in only 1 of the 23 age-matched nondemented controls. In all ATD patients with elevated CSF silicon, symptoms began after age 65. Thirty-four percent of 29 patients with other types of dementia also had elevated CSF silicon. Therefore, elevated CSF silicon concentrations are not specific for ATD, but they correlate with age and severity of functional impairment in late-onset ATD.

Cerebrospinal fluid trace element content in dementia: clinical, radiologic, and pathologic correlations.

Using inductively coupled argon plasma emission spectroscopy, we measured 19 trace elements in cerebrospinal fluid of 265 patients who were undergoing diagnostic lumbar puncture. Thirty-three patients had Alzheimer-type dementia (ATD); 16 patients had other dementing illnesses; and 20 had no neurologic disease. There were seven cases of autopsy-proven Alzheimer's disease (AD) and eight autopsy controls. We found elevated CSF silicon in 24% of ATD and 71% of AD patients. We found no relationship between CSF aluminum, arsenic, lead, or manganese and ATD, AD, or other dementing illnesses.

Silicon as a potential uremic neurotoxin: trace element analysis in patients with renal failure.

We analyzed multiple trace elements in tap water, dialysis fluids, and CSF of patients on dialysis and with chronic renal insufficiency. Before placement of a deionizer in the dialysis unit, we found elevated levels of aluminum, barium, copper, silicon, and zinc in tap water and dialysis fluids. These were corrected by the deionizer. CSF silicon content was increased in patients with chronic renal insufficiency and on dialysis; CSF aluminum, barium, copper, and zinc were normal.

Postmortem management of patient affairs: the resident's perspective.

The role of residents continues to evolve, and they are finding themselves increasingly being asked to request an autopsy from a grieving family. Although much has been written previously concerning the need for residents to be more aggressive in obtaining autopsy, this article suggests that structural problems must be addressed if the current low autopsy rate is to be improved.

Experience with community academic practice: strategies for the ambulatory education of residents.

The expectation that training programs will place more of their physician graduates into primary care has caused internal medicine programs to explore different educational experiences for their residents. One proposal is to transfer the ambulatory training site for residents from the hospital clinic to a community academic practice (CAP) site. We discuss the theoretical aspects, the practical considerations, and our experience with one CAP site, including the problems that have been solved and the problems remaining.

Transient superior vena cava syndrome due to propylthiouracil therapy in intrathoracic goiter.

Intrathoracic goiter is a rare cause of superior vena cava syndrome. We present the findings in a patient in whom the syndrome was precipitated by therapy with propylthiouracil and remitted on withdrawal of the medication. The superior vena cava syndrome did not recur on medical management, suggesting that surgery is not always indicated in this setting.

Assessing clinical experience in a residency training program.

Training programs are expected to provide experience to residents and students such that a reasonable spectrum of diseases and severity of illness are encountered. One approach is to have the resident or student keep a record of the cases encountered. A clinical experience is much more than the patients completely evaluated and treated by the resident or student. We propose a program approach in which all patients admitted to the medical service are categorized by several standard methods. This study describes an evaluation of a patient population seen by medical residents and students with specific demographic information and the spectrum and severity of their diseases. The numbers of patients and the severity of illness of the patients cared for during the ward experience affect the educational value of the program. This type of information has implications for the evaluation and design of training programs.

Resident knowledge of charges: are we asking the right questions?

Physician knowledge of costs and charges for medical services is thought to have substantial relevance for cost containment. Unfortunately, numerous studies have demonstrated the difficulties in using educational techniques to improve knowledge and reduce charges. Furthermore, reductions in charges, when achieved, have not correlated with improved physician knowledge. The authors examined several methods of ascertaining physician knowledge of charges and they suggest that previous methods may have been too insensitive. Previous reports may have underestimated physician knowledge of costs and charges.

Delivery of vaccines to adults: correlations with physician knowledge and patient variables.

Our objective was to explore reasons why vaccines are not provided to adult patients receiving primary health care. The study setting was a primary health care clinic in a urban hospital staffed primarily by residents and teaching faculty. The patients were identified as all continuity care patients with a scheduled visit to the clinic during the 4-week study period in April 1995. The providers were all primary care providers for the patients during the study period. The providers were given two surveys before the study: one to assess their knowledge of published preventive health care guidelines and one to assess their perspective of the guidelines. During the study period, the charts of the patients were reviewed for the services they had received. An assessment was placed in each patient's chart for the provider's completion during the visit. The assessment enabled the provider to explain why services had not been provided. The results showed that influenza, pneumococcal, and diphtheria-tetanus vaccines were provided at varying rates. Each vaccine had a different profile as to noncompliance with guidelines. Lack of provider knowledge of the guideline was most apparent with pneumococcal vaccine. Providers' ambivalence regarding the scientific basis and/or clinical importance was most apparent with influenza vaccine. Patient refusal was a prominent cause with influenza vaccine in the elderly. Patient appointment behavior (opportunity for care and compliance) also seemed to play an important role. We conclude that explanations for nondelivery of vaccines to adults seem to be multiple. Lack of physician knowledge and physician perception of the guidelines provide some explanations. Patient-related factors including refusal, decreased opportunity for care, and noncompliance also play important roles in why vaccinations are not provided. Improvement in the rates at which immunizations to adults are provided will require interventions in multiple areas.

Barriers to control of blood glucose in diabetes mellitus.

The purpose of this study was to characterize the barriers to tight control of diabetes mellitus. The study collected data from multiple sources at a primary health care clinic in an academic teaching hospital serving an urban population, including patients' charts, structured interviews with patients, a survey of physicians' general perspectives and beliefs concerning diabetes mellitus, and a physician's structured review of barriers to tight control for individual patients. One hundred thirty-five patients with scheduled appointments were eligible for the study, of whom 94% had had a recent hemoglobin A1C (HbA1C). Seventy-seven of 88 patients (88%) who presented for their appointments consented to the interview, 48 of 50 providers (96%) returned useable surveys, and providers completed individual assessments for 96 patients (71%). Patients had a mean age of 61 years, an average of 7.60 diagnoses, and an average of 8.96 prescriptions. Their diabetes control was less than ideal, with less than 15% having normal or near normal control and almost a quarter having poor control. Correlations of HbA1C with age and show rate were seen. Physicians' assessments showed that motivation and understanding of diabetes and compliance with diet and medications correlated with diabetes control. Neither patient knowledge nor physician knowledge appeared to be a problem, nor did either correlate with diabetes control. The number of barriers to control were many, with over half of the patients having five or more barriers. Tight control of blood glucose is felt to be an important aspect of quality care for diabetic patients. In this study, a representative sample of diabetic patients had less than ideal diabetes control. This population was receiving their care in an urban setting and had many comorbid illnesses and many barriers to control. Age, motivation, understanding of the disease, show rate, and compliance with diet and medications had statistical correlations with diabetes control. In order to improve the quality of care for diabetic patients, barriers to care must be addressed.

Assessment of delivery of preventive health services.

Our objective was to design and evaluate an instrument to assess the performance of a clinic in the delivery of preventive health services to a general medical clinic population. The patients were identified prospectively; data were obtained retrospectively with review of the charts. The study was conducted in a primary care clinic staffed primarily by internal medicine residents in an urban academic medical center. Patients who were receiving continuity care in the clinic and who were scheduled for an appointment during the 4-week study period were eligible for inclusion. Patients were identified by the appointment schedule. Charts were reviewed for the delivery of preventive health services. Data were abstracted utilizing a standard instrument. We found that the rate at which services were provided varied considerably by service and over time. The techniques used provided some insight into methods for the evaluation of the delivery of preventive services. It should be possible to assess a clinic's performance over a range of services over its entire population over time. An understanding of this more global performance may provide a better tool for managers and researchers addressing these issues. There may be legitimate reasons for services not being provided. These issues are complex and require sensitive, detailed investigation.

Update on screening for type 2 diabetes. The why, who, how, and what of testing and diagnosing.

Type 2 diabetes can cause serious complications even as it remains undiagnosed. Screening is recommended only in people with risk factors for the disease. The ADA recommends FPG as the test of choice, but RPG is also a practical alternative because it is easier and more convenient. Frequency of rescreening if the first screen result is normal depends on the number of risk factors present. Physicians should realize the importance of a confirmatory test and not base a diagnosis of diabetes on a single value unless the value is so high that the diagnosis is unequivocal.