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Bioorg Med Chem Lett
; 14(1): 21-4, 2004 Jan 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-14684289
RESUMEN
Novel classes of thienopyrimidines and thienopyridines have been identified as potent inhibitors of VEGFR-2 kinase. The synthesis and SAR of these compounds is presented, along with successful efforts to diminish EGFR activity present in the lead series.