Leftover drug disposal: Customer behavior, pharmacist recommendations, and obstacles to drug take-back box implementation.

Production and use of pharmaceuticals in the United States is high and continues to grow. This, combined with poor wastewater removal rates for drugs in excreted waste, and improper pharmaceutical disposal leads to the presence of pharmaceuticals in fresh- and marine waters and wildlife. In the United States, safe drug take-back boxes, or dropboxes, were established in pharmacies after federal legislation passed in 2014, allowing for year-round safe collection of leftover pharmaceuticals. The overarching objective of this work was to identify opportunities for improving access to proper pharmaceutical disposal. We assessed consumer behavior regarding drug disposal choices and knowledge of dropboxes at pharmacies, investigated pharmacist attitudes toward and recommendations about leftover drug disposal, and compared responses at locations with and without dropboxes. We also explored obstacles to dropbox adoption and usage. We found that customer awareness of dropboxes as well as knowledge about risks of improper disposal are low, however awareness was greater at pharmacies with dropboxes. Additionally, pharmacists at dropbox locations were more consistent in their messaging to customers, more likely to recommend proper disposal methods, and more supportive of drug take-back programs. Through a focus group, we learned that further consumer education would overwhelm the capacity of the existing dropboxes. Based on our findings, we recommend solutions to improper disposal focus on legislation mandating dropboxes at pharmacies and pressure on the pharmaceutical industry to fund proper disposal of unused pharmaceuticals.

Microplastic Prevalence in 4 Oregon Rivers Along a Rural to Urban Gradient Applying a Cost-Effective Validation Technique.

Microplastics are ubiquitous in our environment and are found in rivers, streams, oceans, and even tap water. Riverine microplastics are relatively understudied compared with those in marine ecosystems. In Oregon (USA), we sampled 8 sites along 4 freshwater rivers spanning rural to urban areas to quantify microplastics. Plankton tow samples from sites along the Columbia, Willamette, Deschutes, and Rogue Rivers were analyzed using traditional light microscopy for initial microplastic counts. Application of Nile Red dye to validate microplastics improved microplastic identification, particularly for particles (Wilcox test; p = 0.001). Nile Red-corrected microfiber abundance was correlated with human population within 5 km of the sample site (R² = 0.554), although no such relationship was observed between microparticles and population (R² = 0.183). We found that plastics were present in all samples from all sites, despite the range from undeveloped, remote stretches of river in rural areas to metropolitan sites within Portland (OR, USA), demonstrating the pervasive presence of plastic pollution in freshwater ecosystems. Environ Toxicol Chem 2020;39:1590-1598. © 2020 SETAC.

Proceed with caution: The need to raise the publication bar for microplastics research.

Plastic is a ubiquitous contaminant of the Anthropocene. The highly diverse nature of microplastic pollution means it is not a single contaminant, but a suite of chemicals that include a range of polymers, particle sizes, colors, morphologies, and associated contaminants. Microplastics research has rapidly expanded in recent years and has led to an overwhelming consideration in the peer-reviewed literature. While there have been multiple calls for standardization and harmonization of the research methods used to study microplastics in the environment, the complexities of this emerging field have led to an exploration of many methods and tools. While different research questions require different methods, making standardization often impractical, it remains import to harmonize the outputs of these various methodologies. We argue here that in addition to harmonized methods and quality assurance practices, journals, editors and reviewers must also be more proactive in ensuring that scientific papers have clear, repeatable methods, and contribute to a constructive and factual discourse on plastic pollution. This includes carefully considering the quality of the manuscript submissions and how they fit into the larger field of research. While comparability and reproducibility is critical in all fields, we argue that this is of utmost importance in microplastics research as policy around plastic pollution is being developed in real time alongside this evolving scientific field, necessitating the need for rigorous examination of the science being published.