1.
Org Biomol Chem
; 16(3): 389-392, 2018 01 17.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29271460
RESUMEN
Stapled peptides are gaining tremendous interest as next-generation therapeutic agents to target protein-protein interactions. Herein, we report an intramolecular peptide stapling method which links two tryptophan residues at the C2 position of the indole moieties via acid-mediated condensation with an aldehyde.