RESUMEN
A 25-year-old pregnant patient developed life-threatening asthma refractory to all standard treatment including anaesthetic agents. Ventilatory pressures continued to rise with impending cardio-respiratory arrest. The introduction of nebulised endotracheal DNase however resulted in a rapid and dramatic improvement with good clinical outcome.
Asunto(s)
Asma/tratamiento farmacológico , Desoxirribonucleasas/administración & dosificación , Nebulizadores y Vaporizadores , Adulto , Femenino , Humanos , Embarazo , Resultado del TratamientoRESUMEN
The fact that exercise-induced bronchoconstriction (EIB) may be both over- and underdiagnosed in athletes has led to calls for widespread screening for the condition. This article assesses such a strategy by employing the standard framework used when evaluating any screening policy. This approach highlights a number of concerns and allows recommendations to help optimize the success of such a strategy if it were to be implemented.
Asunto(s)
Asma Inducida por Ejercicio/epidemiología , Asma Inducida por Ejercicio/prevención & control , Tamizaje Masivo/normas , Deportes/normas , Humanos , Formulación de Políticas , PrevalenciaRESUMEN
A 73-year-old former smoker with previous occupational exposure to asbestos presented with a pneumothorax that was initially managed by simple aspiration. Despite this, it re-accumulated and a bronchopleural fistula was suspected. A video-assisted thoracoscopic procedure was performed and revealed an abnormally thickened pleura that turned out to be a mesothelioma. All persistent pneumothoraces should be investigated.