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1.

Ca²⁺ -Calmodulin-Calcineurin Signaling Modulates α-Synuclein Transmission.

Ueda, Jun; Uemura, Norihito; Ishimoto, Tomoyuki; Taguchi, Tomoyuki; Sawamura, Masanori; Nakanishi, Etsuro; Ikuno, Masashi; Matsuzawa, Shuichi; Yamakado, Hodaka; Takahashi, Ryosuke.

Mov Disord ; 38(6): 1056-1067, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37066491

2.

Genetic and clinical landscape of childhood cerebellar hypoplasia and atrophy.

Sakamoto, Masamune; Iwama, Kazuhiro; Sasaki, Masayuki; Ishiyama, Akihiko; Komaki, Hirofumi; Saito, Takashi; Takeshita, Eri; Shimizu-Motohashi, Yuko; Haginoya, Kazuhiro; Kobayashi, Tomoko; Goto, Tomohide; Tsuyusaki, Yu; Iai, Mizue; Kurosawa, Kenji; Osaka, Hitoshi; Tohyama, Jun; Kobayashi, Yu; Okamoto, Nobuhiko; Suzuki, Yume; Kumada, Satoko; Inoue, Kenji; Mashimo, Hideaki; Arisaka, Atsuko; Kuki, Ichiro; Saijo, Harumi; Yokochi, Kenji; Kato, Mitsuhiro; Inaba, Yuji; Gomi, Yuko; Saitoh, Shinji; Shirai, Kentaro; Morimoto, Masafumi; Izumi, Yuishin; Watanabe, Yoriko; Nagamitsu, Shin-Ichiro; Sakai, Yasunari; Fukumura, Shinobu; Muramatsu, Kazuhiro; Ogata, Tomomi; Yamada, Keitaro; Ishigaki, Keiko; Hirasawa, Kyoko; Shimoda, Konomi; Akasaka, Manami; Kohashi, Kosuke; Sakakibara, Takafumi; Ikuno, Masashi; Sugino, Noriko; Yonekawa, Takahiro; Gürsoy, Semra.

Genet Med ; 24(12): 2453-2463, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36305856

3.

Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.

Sawamura, Masanori; Onoe, Hirotaka; Tsukada, Hideo; Isa, Kaoru; Yamakado, Hodaka; Okuda, Shinya; Ikuno, Masashi; Hatanaka, Yusuke; Murayama, Shigeo; Uemura, Norihito; Isa, Tadashi; Takahashi, Ryosuke.

Mov Disord ; 37(10): 2033-2044, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-35989519

4.

Striatal-Inoculation of α-Synuclein Preformed Fibrils Aggravated the Phenotypes of REM Sleep without Atonia in A53T BAC-SNCA Transgenic Mice.

Okuda, Shinya; Nakayama, Takeo; Uemura, Norihito; Hikawa, Rie; Ikuno, Masashi; Yamakado, Hodaka; Inoue, Haruhisa; Tachibana, Naoko; Hayashi, Yu; Takahashi, Ryosuke; Egawa, Naohiro.

Int J Mol Sci ; 23(21)2022 Nov 02.

Artículo en Inglés | MEDLINE | ID: mdl-36362177

5.

GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.

Ikuno, Masashi; Yamakado, Hodaka; Akiyama, Hisako; Parajuli, Laxmi Kumar; Taguchi, Katsutoshi; Hara, Junko; Uemura, Norihito; Hatanaka, Yusuke; Higaki, Katsumi; Ohno, Kousaku; Tanaka, Masaki; Koike, Masato; Hirabayashi, Yoshio; Takahashi, Ryosuke.

Hum Mol Genet ; 28(11): 1894-1904, 2019 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-30689867

6.

Perampanel Inhibits α-Synuclein Transmission in Parkinson's Disease Models.

Ueda, Jun; Uemura, Norihito; Sawamura, Masanori; Taguchi, Tomoyuki; Ikuno, Masashi; Kaji, Seiji; Taruno, Yosuke; Matsuzawa, Shuichi; Yamakado, Hodaka; Takahashi, Ryosuke.

Mov Disord ; 36(7): 1554-1564, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-33813737

7.

α-Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC-SNCA Mice.

Uemura, Norihito; Ueda, Jun; Yoshihara, Toru; Ikuno, Masashi; Uemura, Maiko T; Yamakado, Hodaka; Asano, Masahide; Trojanowski, John Q; Takahashi, Ryosuke.

Mov Disord ; 36(9): 2036-2047, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-33547846

8.

α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.

Taguchi, Tomoyuki; Ikuno, Masashi; Hondo, Mari; Parajuli, Laxmi Kumar; Taguchi, Katsutoshi; Ueda, Jun; Sawamura, Masanori; Okuda, Shinya; Nakanishi, Etsuro; Hara, Junko; Uemura, Norihito; Hatanaka, Yusuke; Ayaki, Takashi; Matsuzawa, Shuichi; Tanaka, Masaki; El-Agnaf, Omar M A; Koike, Masato; Yanagisawa, Masashi; Uemura, Maiko T; Yamakado, Hodaka; Takahashi, Ryosuke.

Brain ; 143(1): 249-265, 2020 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-31816026

9.

Animal Model for Prodromal Parkinson's Disease.

Taguchi, Tomoyuki; Ikuno, Masashi; Yamakado, Hodaka; Takahashi, Ryosuke.

Int J Mol Sci ; 21(6)2020 Mar 13.

Artículo en Inglés | MEDLINE | ID: mdl-32183024

10.

Animal models for Parkinson's disease.

Ikuno, Masashi; Takahashi, Ryosuke.

Nihon Rinsho ; 75(1): 42-46, 2017 Jan.

Artículo en Inglés, Japonés | MEDLINE | ID: mdl-30566293

11.

Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice.

Okuda, Shinya; Uemura, Norihito; Sawamura, Masanori; Taguchi, Tomoyuki; Ikuno, Masashi; Uemura, Maiko T; Yamakado, Hodaka; Takahashi, Ryosuke.

Neurotherapeutics ; 19(1): 289-304, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34935120

12.

Mitochondrial dysfunction in a mouse model of prodromal Parkinson's disease: A metabolomic analysis.

Ikuno, Masashi; Yamakado, Hodaka; Amano, Ikuko; Hatanaka, Yusuke; Uemura, Norihito; Matsuzawa, Shu-Ichi; Takahashi, Ryosuke.

Neurosci Lett ; 765: 136267, 2021 11 20.

Artículo en Inglés | MEDLINE | ID: mdl-34571089

13.

Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson's Disease.

Parajuli, Laxmi Kumar; Wako, Ken; Maruo, Suiki; Kakuta, Soichiro; Taguchi, Tomoyuki; Ikuno, Masashi; Yamakado, Hodaka; Takahashi, Ryosuke; Koike, Masato.

eNeuro ; 7(4)2020.

Artículo en Inglés | MEDLINE | ID: mdl-32817196

14.

Real-world pharmacological treatment patterns of patients with young-onset Parkinson's disease in Japan: a medical claims database analysis.

Kasamo, Sachiko; Takeuchi, Masato; Ikuno, Masashi; Kawasaki, Yohei; Tanaka, Shiro; Takahashi, Ryosuke; Kawakami, Koji.

J Neurol ; 266(8): 1944-1952, 2019 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-31076875

15.

Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.

Fujita, Kyota; Homma, Hidenori; Kondo, Kanoh; Ikuno, Masashi; Yamakado, Hodaka; Tagawa, Kazuhiko; Murayama, Shigeo; Takahashi, Ryosuke; Okazawa, Hitoshi.

eNeuro ; 5(4)2018.

Artículo en Inglés | MEDLINE | ID: mdl-30225354

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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