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1.
Cost Eff Resour Alloc ; 22(1): 10, 2024 Jan 30.
Artículo en Inglés | MEDLINE | ID: mdl-38291472

RESUMEN

Preference elicitation is widely used within health economic evaluations to inform coverage decisions. However, coverage decisions involve questions of social justice and it is unclear what role empirical evidence about preferences can play here. This study reviews the prevalent normative frameworks for using population-based preference elicitation and the criticisms they face, and proposes an alternative based on constitutional economics. The frameworks reviewed include a supposedly value-neutral framework of preferences as predictors of choice, preference utilitarian frameworks that aim to maximize preference satisfaction, and substantive consequentialist frameworks that aim to maximize happiness, health, or capabilities. The proposed alternative implements the idea that indices of social value are tools for conflict resolution, rather than tools for maximization. Preference elicitation is used for validating values generated by multi-criteria decision analysis results within representative processes of stakeholder deliberation.

2.
Cost Eff Resour Alloc ; 17: 29, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31866768

RESUMEN

BACKGROUND: The question of appropriate discount rates in health economic evaluations has been a point of continuous scientific debate. Today, it is widely accepted that, under certain conditions regarding the social objective of the healthcare decision maker and the fixity of the budget for healthcare, a lower discount rate for health gains than for costs is justified if the consumption value of health is increasing over time. To date, however, there is neither empirical evidence nor a strong theoretical a priori supporting this assumption. Given this lack of evidence, we offer an additional approach to check the appropriateness of differential discounting. METHODS: Our approach is based on a two-goods extension of Ramsey's optimal growth model which allows accounting for changing relative values of goods explicitly. Assuming a constant elasticity of substitution (CES) utility function, the growth rate of the consumption value of health depends on three variables: the growth rate of consumption, the growth rate of health, and the income elasticity of the willingness to pay for health. Based on a review of the empirical literature on the monetary value of health, we apply the approach to obtain an empirical value of the growth rate of the consumption value of health in Germany. RESULTS: The empirical literature suggests that the income elasticity of the willingness to pay for health is probably not larger but rather smaller than 1 and probably not smaller but rather larger than 0.2. Combining this finding with reasonable values of the annual growth rates in consumption (1.5-1.6%) and health (0.1%) suggests, for Germany, an annual growth rate of the consumption value of health between 0.3 and 1.5%. CONCLUSION: In the light of a two-goods extension of Ramsey's optimal growth model, the available empirical evidence makes the case for a growing consumption value of health. Therefore, the current German practice of applying the same discount rate to costs and health gains introduces a systematic bias against healthcare technologies with upfront costs and long-term health effects. Differential discounting with a lower rate for health effects appears to be a more appropriate discounting model.

3.
BMC Health Serv Res ; 13: 424, 2013 Oct 19.
Artículo en Inglés | MEDLINE | ID: mdl-24139278

RESUMEN

BACKGROUND: The evidence on the long-term economic effects of obesity is still scarce. This study aims to analyse the impact of body mass index (BMI) and BMI-change on future pharmaceutical utilisation and expenditures. METHODS: Based on data from 2,946 participants in a German population-based health survey (MONICA/KORA, 1994/95) and the follow-up study (2004/05), drug intake and expenditures were estimated using a bottom-up approach. Using univariate and multivariate methods, we analysed the impact of baseline BMI and BMI-change on drug utilisation and expenditures after 10 years. RESULTS: The use of pharmaceuticals was more likely in moderately and severely obese compared to the normal weight group (OR 1.8 and 4.0, respectively). In those who reported pharmaceutical intake, expenditures were about 40% higher for the obese groups. A 1-point BMI-gain in 10 years was, on average, associated with almost 6% higher expenditures compared to a constant BMI. CONCLUSION: The results suggest that obesity as well as BMI-gain are strong predictors of future drug utilisation and associated expenditures in adults, and thus highlight the necessity of timely and effective intervention and prevention programmes. This study complements the existing literature and provides important information on the relevance of obesity as a health problem.


Asunto(s)
Índice de Masa Corporal , Costos de los Medicamentos/estadística & datos numéricos , Obesidad/economía , Estudios de Cohortes , Quimioterapia/economía , Quimioterapia/estadística & datos numéricos , Femenino , Estudios de Seguimiento , Alemania/epidemiología , Gastos en Salud/estadística & datos numéricos , Encuestas Epidemiológicas , Humanos , Masculino , Persona de Mediana Edad , Obesidad/tratamiento farmacológico , Obesidad Mórbida/tratamiento farmacológico , Obesidad Mórbida/economía , Sobrepeso/tratamiento farmacológico , Sobrepeso/economía , Factores Socioeconómicos
4.
BMC Health Serv Res ; 12: 300, 2012 Sep 04.
Artículo en Inglés | MEDLINE | ID: mdl-22947299

RESUMEN

BACKGROUND: Economic evaluation of newborn screening poses specific methodological challenges. Amongst others, these challenges refer to the use of quality adjusted life years (QALYs) in newborns, and which costs and outcomes need to be considered in a full evaluation of newborn screening programmes. Because of the increasing scale and scope of such programmes, a better understanding of the methods of high-quality economic evaluations may be crucial for both producers/authors and consumers/reviewers of newborn screening-related economic evaluations. The aim of this study was therefore to develop specific guidelines designed to assess and improve the methodological quality of economic evaluations in newborn screening. METHODS: To develop the guidelines, existing guidelines for assessing the quality of economic evaluations were identified through a literature search, and were reviewed and consolidated using a deductive iterative approach. In a subsequent test phase, these guidelines were applied to various economic evaluations which acted as case studies. RESULTS: The guidelines for assessing and improving the methodological quality of economic evaluations in newborn screening are organized into 11 categories: "bibliographic details", "study question and design", "modelling", "health outcomes", "costs", "discounting", "presentation of results", "sensitivity analyses", "discussion", "conclusions", and "commentary". CONCLUSIONS: The application of the guidelines highlights important issues regarding newborn screening-related economic evaluations, and underscores the need for such issues to be afforded greater consideration in future economic evaluations. The variety in methodological quality detected by this study reveals the need for specific guidelines on the appropriate methods for conducting sound economic evaluations in newborn screening.


Asunto(s)
Enfermedades Genéticas Congénitas/diagnóstico , Pruebas Genéticas/economía , Enfermedades Metabólicas/diagnóstico , Tamizaje Neonatal/economía , Guías de Práctica Clínica como Asunto/normas , Análisis Costo-Beneficio , Pruebas Genéticas/métodos , Humanos , Recién Nacido
5.
BMC Health Serv Res ; 11: 9, 2011 Jan 13.
Artículo en Inglés | MEDLINE | ID: mdl-21232111

RESUMEN

BACKGROUND: This study's aim was to develop a first quantification of the frequency and costs of adverse drug events (ADEs) originating in ambulatory medical practice in Germany. METHODS: The frequencies and costs of ADEs were quantified for a base case, building on an existing cost-of-illness model for ADEs. The model originates from the U.S. health care system, its structure of treatment probabilities linked to ADEs was transferred to Germany. Sensitivity analyses based on values determined from a literature review were used to test the postulated results. RESULTS: For Germany, the base case postulated that about 2 million adults ingesting medications have will have an ADE in 2007. Health care costs related to ADEs in this base case totalled 816 million Euros, mean costs per case were 381 Euros. About 58% of costs resulted from hospitalisations, 11% from emergency department visits and 21% from long-term care. Base case estimates of frequency and costs of ADEs were lower than all estimates of the sensitivity analyses. DISCUSSION: The postulated frequency and costs of ADEs illustrate the possible size of the health problems and economic burden related to ADEs in Germany. The validity of the U.S. treatment structure used remains to be determined for Germany. The sensitivity analysis used assumptions from different studies and thus further quantified the information gap in Germany regarding ADEs. CONCLUSIONS: This study found costs of ADEs in the ambulatory setting in Germany to be significant. Due to data scarcity, results are only a rough indication.


Asunto(s)
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Costos de la Atención en Salud/estadística & datos numéricos , Costos de Hospital/estadística & datos numéricos , Adulto , Atención Ambulatoria/economía , Quimioterapia/economía , Servicio de Urgencia en Hospital/economía , Alemania , Investigación sobre Servicios de Salud , Mortalidad Hospitalaria , Hospitalización/economía , Hospitalización/estadística & datos numéricos , Humanos , Cuidados a Largo Plazo/economía
6.
Curr Opin Clin Nutr Metab Care ; 13(3): 305-13, 2010 May.
Artículo en Inglés | MEDLINE | ID: mdl-20179587

RESUMEN

PURPOSE OF REVIEW: The rising prevalence of obesity amongst children and adolescents is a growing public health burden. This study reviews recent studies, first, examining the economic consequences of childhood obesity, and, second, evaluating the cost-effectiveness of programs to prevent and to manage childhood obesity. RECENT FINDINGS: Evidence of the impact of childhood obesity on healthcare costs for children is ambiguous. Although one study did not find increasing costs with increasing body mass index (BMI), in some other studies this effect was visible--partly only in subgroups. The evaluation studies show that in order to reach acceptable cost-effectiveness values, interventions cannot focus solely on physical activity, but must include nutrition as an intervention target. Moreover, there is some evidence supporting the expectation that childhood obesity prevention may be successful in combining health gains with net cost savings. SUMMARY: There is a need to estimate the costs of childhood obesity as an essential part of identifying cost-effective treatment and prevention measures. Given the diversity and shortcomings of the methodological approaches chosen in the existing evaluation studies, there is an urgent need both for more standardized economic evaluations of those measures and more methodological research.


Asunto(s)
Fenómenos Fisiológicos Nutricionales Infantiles , Costos de la Atención en Salud , Obesidad/economía , Índice de Masa Corporal , Niño , Análisis Costo-Beneficio , Dieta , Ejercicio Físico , Humanos , Obesidad/prevención & control , Obesidad/terapia , Terapéutica/economía
7.
Am J Nephrol ; 31(3): 222-9, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20068286

RESUMEN

BACKGROUND: Chronic kidney disease (CKD) is common, but the longitudinal effects of CKD and associated comorbidities on health care costs in the general population are unknown. METHODS: Population-based cohort study of 2,988 subjects in Germany, aged 25-74 years at baseline, who participated both in the baseline and 10-year follow-up examination (1994/95-2004/05). Presence of CKD was based on serum creatinine and defined as an estimated glomerular filtration rate of <60 ml/min/1.73 m(2). Self-reported health services utilization was used to estimate costs. RESULTS: Health care costs at baseline and follow-up were higher for subjects with CKD. Controlling for socio-economics, lifestyle factors and comorbid conditions, subjects with baseline CKD, in comparison to those without, exhibited 65% higher total costs 10 years after baseline examination, corresponding to a difference in adjusted costs of EUR 743. Incident CKD was related to 38% higher total costs. Costs for inpatient treatment and drug costs were the major costs components, while CKD revealed no effect on outpatient costs. The effect of CKD was strongly modified by angina, myocardial infarction, diabetes, and anemia. CONCLUSIONS: The direct effect of CKD on costs is modified by comorbid conditions. Therefore, early treatment of CKD and its precipitous factors may save future health care costs.


Asunto(s)
Costos de la Atención en Salud/estadística & datos numéricos , Insuficiencia Renal Crónica/economía , Insuficiencia Renal Crónica/epidemiología , Adulto , Anciano , Amidohidrolasas/sangre , Comorbilidad , Estudios de Seguimiento , Alemania/epidemiología , Tasa de Filtración Glomerular , Costos de Hospital/estadística & datos numéricos , Humanos , Incidencia , Persona de Mediana Edad , Pacientes Ambulatorios/estadística & datos numéricos
8.
Health Policy ; 89(2): 184-92, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-18619704

RESUMEN

OBJECTIVES: Our contribution aims to explore the different ways in which early economic data can inform public health policy decisions on new medical technologies. METHODS: A literature research was conducted to detect methodological contributions covering the health policy perspective. RESULTS: Early economic data on new technologies can support public health policy decisions in several ways. Embedded in horizon scanning and HTA activities, it adds to monitoring and assessment of innovations. It can play a role in the control of technology diffusion by informing coverage and reimbursement decisions as well as the direct public promotion of healthcare technologies, leading to increased efficiency. Major problems include the uncertainty related to economic data at early stages as well as the timing of the evaluation of an innovation. CONCLUSIONS: Decision-makers can benefit from the information supplied by early economic data, but the actual use in practice is difficult to determine. Further empirical evidence should be gathered, while the use could be promoted by further standardization.


Asunto(s)
Atención a la Salud/economía , Difusión de Innovaciones , Política de Salud , Salud Pública , Análisis Costo-Beneficio , Humanos , Reembolso de Seguro de Salud
9.
Br J Health Psychol ; 14(Pt 4): 717-34, 2009 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-19187576

RESUMEN

OBJECTIVES: Obesity has been shown to be negatively related to physical health-related quality of life (HQOL) much more strongly than mental HQOL. This is remarkable given findings on obesity-related social stigmata and associations with depression. Considering obesity as a stressor, this study tests for a moderating role of social support for obesity/HQOL associations among women and men. DESIGN: Data come from N=2,732 participants aged 35-74 years in a 2004-2005 general population survey in the Augsburg region, Germany. METHODS: Body weight and height were assessed by anthropometric measurements (classified by body mass index using WHO standards), social support by the Social Support Questionnaire 14-item Short-Form (F-SozU-K14) and HQOL by the 12-item Short-Form Health Survey (SF-12). In multiple regression and general linear models, age, education, family status, health insurance, and place of residence were adjusted for. RESULTS: Among both genders, obesity was associated with reduced physical but not mental HQOL. Among men reporting strong social support, physical HQOL was impaired neither in the moderately nor the severely obese group (compared with normal weight), while it was given less social support. Among women, poor physical HQOL was associated with obesity regardless of social support. CONCLUSIONS: In this adult population sample, no association was found for obesity with mental HQOL. In contrast, a negative association with physical HQOL exists for all subgroups except men with strong social support, indicating that social support buffers obesity-related impairments in physical HQOL in men but not in women. This suggests that obese women and men with strong social support represent distinct populations, with possible implications for obesity care.


Asunto(s)
Estado de Salud , Obesidad/psicología , Calidad de Vida/psicología , Apoyo Social , Adulto , Anciano , Femenino , Alemania , Humanos , Masculino , Persona de Mediana Edad , Modelos Estadísticos , Encuestas y Cuestionarios
10.
BMC Health Serv Res ; 8: 194, 2008 Sep 24.
Artículo en Inglés | MEDLINE | ID: mdl-18816378

RESUMEN

BACKGROUND: New products evolving from research and development can only be translated to medical practice on a large scale if they are reimbursed by third-party payers. Yet the decision processes regarding reimbursement are highly complex and internationally heterogeneous. This study develops a process-oriented framework for monitoring these so-called fourth hurdle procedures in the context of product development from bench to bedside. The framework is suitable both for new drugs and other medical technologies. METHODS: The study is based on expert interviews and literature searches, as well as an analysis of 47 websites of coverage decision-makers in England, Germany and the USA. RESULTS: Eight key steps for monitoring fourth hurdle procedures from a company perspective were determined: entering the scope of a healthcare payer; trigger of decision process; assessment; appraisal; setting level of reimbursement; establishing rules for service provision; formal and informal participation; and publication of the decision and supplementary information. Details are given for the English National Institute for Health and Clinical Excellence, the German Federal Joint Committee, Medicare's National and Local Coverage Determinations, and for Blue Cross Blue Shield companies. CONCLUSION: Coverage determination decisions for new procedures tend to be less formalized than for novel drugs. The analysis of coverage procedures and requirements shows that the proof of patient benefit is essential. Cost-effectiveness is likely to gain importance in future.


Asunto(s)
Disciplinas de las Ciencias Biológicas , Toma de Decisiones en la Organización , Transferencia de Tecnología , Disciplinas de las Ciencias Biológicas/organización & administración , Inglaterra , Alemania , Investigación sobre Servicios de Salud , Humanos , Entrevistas como Asunto , Modelos Organizacionales , Mecanismo de Reembolso/organización & administración , Estados Unidos
11.
J Psychosom Res ; 61(4): 553-60, 2006 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-17011365

RESUMEN

OBJECTIVE: The objective of this study was to assess the association of obesity with the utilization of general practitioners (GP), medical specialists (MS), physical therapists (PT), and alternative practitioners (AP), and to elucidate whether body weight dissatisfaction mediates extant associations. METHODS: In an adult population survey (KORA Survey S4 1999/2001) in Augsburg, Germany, anthropometric body mass [body mass index (BMI), kg/m(2)], utilization, physical comorbidities, functional limitations due to body weight, and body weight dissatisfaction were assessed and analyzed via multiple logistic regressions. RESULTS: Obese adults (BMI>or=30) had around double odds of AP, GP, and PT utilization. Regarding AP and, to a lesser extent, PT, body weight dissatisfaction both had direct effects and mediated excess utilization. Most notably, the odds for AP use were about twofold in those who were dissatisfied, and the association of obesity and AP use diminished when adjustment for dissatisfaction was performed. Among overweight participants (25

Asunto(s)
Asociación , Imagen Corporal , Peso Corporal , Terapias Complementarias/estadística & datos numéricos , Personal de Salud , Servicios de Salud/estadística & datos numéricos , Medicina Tradicional , Obesidad/terapia , Satisfacción Personal , Especialidad de Fisioterapia/estadística & datos numéricos , Médicos , Adulto , Anciano , Femenino , Conductas Relacionadas con la Salud , Humanos , Estilo de Vida , Masculino , Persona de Mediana Edad , Encuestas y Cuestionarios
12.
Diabetes Care ; 27(9): 2120-8, 2004 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-15333472

RESUMEN

OBJECTIVE: To compare the cost-effectiveness of different type 2 diabetes screening strategies using population-based data (KORA Survey; Augsburg, Germany; subjects aged 55-74 years), including participation data. RESEARCH DESIGN AND METHODS: The decision analytic model, which had a time horizon of 1 year, used the following screening strategies: fasting glucose testing, the oral glucose tolerance test (OGTT) following fasting glucose testing in impaired fasting glucose (IFG) (fasting glucose + OGTT), OGTT only, and OGTT if HbA(1c) was >5.6% (HbA(1c) + OGTT), all with or without first-step preselection (p). The main outcome measures were costs (in Euros), true-positive type 2 diabetic cases, incremental cost-effectiveness ratios (ICERs), third-party payers, and societal perspectives. RESULTS: After dominated strategies were excluded, the OGTT and HbA(1c) + OGTT from the perspective of the statutory health insurance remained, as did fasting glucose + OGTT and HbA(1c) + OGTT from the societal perspective. OGTTs (4.90 per patient) yielded the lowest costs from the perspective of the statutory health insurance and fasting glucose + OGTT (10.85) from the societal perspective. HbA(1c) + OGTT was the most expensive (21.44 and 31.77) but also the most effective (54% detected cases). ICERs, compared with the next less effective strategies, were 771 from the statutory health insurance and 831 from the societal perspective. In the Monte Carlo analysis, dominance relations remained unchanged in 100 and 68% (statutory health insurance and societal perspective, respectively) of simulated populations. CONCLUSIONS: The most effective screening strategy was HbA(1c) combined with OGTT because of high participation. However, costs were lower when screening with fasting glucose tests combined with OGTT or OGTT alone. The decision regarding which is the most favorable strategy depends on whether the goal is to identify a high number of cases or to incur lower costs at reasonable effectiveness.


Asunto(s)
Diabetes Mellitus Tipo 2/epidemiología , Tamizaje Masivo/economía , Anciano , Análisis Costo-Beneficio , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/economía , Femenino , Alemania/epidemiología , Intolerancia a la Glucosa/diagnóstico , Intolerancia a la Glucosa/epidemiología , Prueba de Tolerancia a la Glucosa , Humanos , Masculino , Persona de Mediana Edad , Prevalencia , Sensibilidad y Especificidad
13.
Eur J Hum Genet ; 23(6): 729-35, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25248395

RESUMEN

Given the cost constraints of the European health-care systems, criteria are needed to decide which genetic services to fund from the public budgets, if not all can be covered. To ensure that high-priority services are available equitably within and across the European countries, a shared set of prioritization criteria would be desirable. A decision process following the accountability for reasonableness framework was undertaken, including a multidisciplinary EuroGentest/PPPC-ESHG workshop to develop shared prioritization criteria. Resources are currently too limited to fund all the beneficial genetic testing services available in the next decade. Ethically and economically reflected prioritization criteria are needed. Prioritization should be based on considerations of medical benefit, health need and costs. Medical benefit includes evidence of benefit in terms of clinical benefit, benefit of information for important life decisions, benefit for other people apart from the person tested and the patient-specific likelihood of being affected by the condition tested for. It may be subject to a finite time window. Health need includes the severity of the condition tested for and its progression at the time of testing. Further discussion and better evidence is needed before clearly defined recommendations can be made or a prioritization algorithm proposed. To our knowledge, this is the first time a clinical society has initiated a decision process about health-care prioritization on a European level, following the principles of accountability for reasonableness. We provide points to consider to stimulate this debate across the EU and to serve as a reference for improving patient management.


Asunto(s)
Servicios de Laboratorio Clínico/legislación & jurisprudencia , Pruebas Genéticas/legislación & jurisprudencia , Servicios de Laboratorio Clínico/ética , Servicios de Laboratorio Clínico/normas , Consenso , Europa (Continente) , Pruebas Genéticas/ética , Pruebas Genéticas/normas , Responsabilidad Social
14.
Expert Rev Pharmacoecon Outcomes Res ; 12(6): 733-43, 2012 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23252356

RESUMEN

As in most countries, overweight and obesity among children and adolescents have dramatically increased in Germany over the last two decades. This serious public-health challenge has stimulated many efforts to curb the pediatric obesity epidemic. In this article, the authors briefly describe these efforts and examine the role of health economics in informing German health policies and evaluating the outcomes of interventions aimed at reducing pediatric obesity. The findings indicate that the tools of health-economic analysis have rarely been used to guide the development of strategies to prevent pediatric obesity and to support decision-making on the use of the scarce resources available for preventive actions. The authors give some reasons why health economics has not been an important policy tool so far and make some recommendations for how this could be changed. Reasons impeding health economics playing a more important role in this area are the existence of many unsolved issues in the methods of health economic evaluation and large gaps in the knowledge base on the effectiveness of interventions. Nevertheless, these methods should be considered to be indispensible tools of health policy development. However, taking into account the broad range of political and societal concerns related to pediatric obesity, decision-making in this area will ultimately rest on a process of deliberate thinking integrating different perspectives among, which health economics will be one.


Asunto(s)
Política de Salud/economía , Obesidad/prevención & control , Sobrepeso/prevención & control , Adolescente , Niño , Toma de Decisiones , Alemania/epidemiología , Humanos , Obesidad/epidemiología , Sobrepeso/epidemiología , Formulación de Políticas
15.
Eur J Health Econ ; 13(2): 127-44, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21170731

RESUMEN

Over the last decades, methods for the economic evaluation of health care technologies were increasingly used to inform reimbursement decisions. For a short time, the German Statutory Health Insurance makes use of these methods to support reimbursement decisions on patented drugs. In this context, the discounting procedure emerges as a critical component of these methods, as discount rates can strongly affect the resulting incremental cost-effectiveness ratios. The aim of this paper is to identify the appropriate value of a social discount rate to be used by the German Statutory Health Insurance for the economic evaluation of health technologies. On theoretical grounds, we build on the widespread view of contemporary economists that the social rate of time preference (SRTP) is the adequate social discount rate. For quantifying the SRTP, we first apply the market behaviour approach, which assumes that the SRTP is reflected in observable market interest rates. As a second approach, we derive the SRTP from optimal growth theory by using the Ramsey equation. A major part of the paper is devoted to specify the parameters of this equation. Depending on various assumptions, our empirical findings result in the range of 1.75-4.2% for the SRTP. A reasonable base case discount rate for Germany, thus, would be about 3%. Furthermore, we deal with the much debated question whether a common discount rate for costs and health benefits or a lower rate for health should be applied in health economic evaluations. In the German social health insurance system, no exogenously fixed budget constraint does exist. When evaluating a new health technology, the health care decision maker is obliged to conduct an economic evaluation in order to examine whether there is an economically appropriate relation between the value of the health gains and the additional costs which are given by the value of the consumption losses due to the additional health care expenditures. Therefore, a discount rate lower than the SRTP for consumption should be applied if an increase in the consumption value of health is expected. However, given the limited empirical evidence on the relationship between consumption and the value of health, it is hardly possible to make reliable forecasts of this value. Regarding the practice of the German evaluation authority, it is not recommended to use differential discounting in the base case. Instead, the issue of differential discounting should be addressed in sensitivity analyses. Reducing the discount rate for health compared to the rate for costs by a figure in the range between near 0% and 3% may be considered to be appropriate for Germany.


Asunto(s)
Tecnología Biomédica/economía , Toma de Decisiones en la Organización , Seguro de Salud/economía , Programas Nacionales de Salud/economía , Toma de Decisiones , Alemania , Servicios de Salud/economía , Necesidades y Demandas de Servicios de Salud/economía , Humanos , Renta , Impuesto a la Renta/economía , Modelos Econométricos , Evaluación de Necesidades
16.
Adv Prev Med ; 2012: 601631, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22536517

RESUMEN

This analysis aims to discuss the implications of the "health asset concept", introduced by the WHO, and the "investment for health model" requiring a "participatory approach" of cooperative programme development applied on a physical activity programme for socially disadvantaged women and to demonstrate the related costing issues as well as the relevant decision context. The costs of programme implementation amounted to €48,700. Adding the costs for developing the programme design of €48,800 results in total costs of €97,500; adding on top of that the costs of asset assessment running to €35,600 would total €133,100. These four different cost figures match four different types of potentially relevant decisions contexts. Depending on the decision context the total costs, and hence the incremental cost-effectiveness ratio of a health promotion intervention, could differ considerably. Therefore, a detailed cost assessment and the identification of the decision context are of crucial importance.

17.
Nutrition ; 28(9): 829-39, 2012 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-22452837

RESUMEN

OBJECTIVE: This review aims to put an economic perspective on childhood and adolescent obesity by providing an overview on the latest literature on obesity-related costs and the cost effectiveness of interventions to prevent or manage the problem. METHODS: The review is based on a comprehensive PubMed/Medline search performed in October 2011. RESULTS: Findings on the economic burden of childhood obesity are inconclusive. Considering the different cost components and age groups, most but not all studies found excess health care costs for obese compared with normal-weight peers. The main limitations relate to short study periods and the strong focus on health care costs, neglecting other components of the economic burden of childhood obesity. The results of the economic evaluations of childhood and adolescent obesity programs support the expectation that preventive and management interventions with acceptable cost effectiveness do exist. Some interventions may even be cost saving. However, owing to the differences in various methodologic aspects, it is difficult to compare preventive and treatment approaches in their cost effectiveness or to determine the most cost-effective timing of preventive interventions during infancy and adolescence. CONCLUSION: To design effective public policies against the obesity epidemic, a better understanding and a more precise assessment of the health care costs and the broader economic burden are necessary but, critically, depend on the collection of additional longitudinal data. The economic evaluation of childhood obesity interventions poses various methodologic challenges, which should be addressed in future research to fully use the potential of economic evaluation as an aid to decision making.


Asunto(s)
Atención a la Salud/economía , Costos de la Atención en Salud , Obesidad/economía , Niño , Costo de Enfermedad , Análisis Costo-Beneficio , Humanos , Obesidad/prevención & control , Obesidad/terapia
18.
Respir Med ; 106(4): 540-8, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22100535

RESUMEN

AIM: While it is known that severe COPD has substantial economic consequences, evidence on resource use and costs in mild disease is scarce. The objective of this study was to investigate excess costs of early stages of COPD. METHODS: Using data from two population-based studies in Southern Germany, current GOLD criteria were applied to pre-bronchodilator spirometry for COPD diagnosis and staging in 2255 participants aged 41 to 89. Utilization of physician visits, hospital stays and medication was compared between participants with COPD stage I, stage II+ (II or higher) and controls. Costs per year were calculated by applying national unit costs. In controlling for confounders, two-part generalized regression analyses were used to account for the skewed distribution of costs and the high proportion of subjects without costs. RESULTS: Utilization in all categories was significantly higher in COPD patients than in controls. After adjusting for confounders, these differences remained present in physician visits and medication, but not in hospital days. Adjusted annual costs did not differ between stage I (€ 1830) and controls (€ 1822), but increased by about 54% to € 2812 in stage II+. CONCLUSION: The finding that utilization and costs are considerably higher in moderate but not in mild COPD highlights the economic importance of prevention and of interventions aiming at early diagnosis and delayed disease progression.


Asunto(s)
Atención a la Salud/estadística & datos numéricos , Costos de la Atención en Salud/estadística & datos numéricos , Enfermedad Pulmonar Obstructiva Crónica/economía , Adulto , Anciano , Anciano de 80 o más Años , Atención Ambulatoria/economía , Atención Ambulatoria/estadística & datos numéricos , Estudios de Cohortes , Comorbilidad , Costos de los Medicamentos/estadística & datos numéricos , Utilización de Medicamentos/estadística & datos numéricos , Escolaridad , Femenino , Alemania , Hospitalización/economía , Hospitalización/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Visita a Consultorio Médico/estadística & datos numéricos , Enfermedad Pulmonar Obstructiva Crónica/tratamiento farmacológico , Índice de Severidad de la Enfermedad
19.
Nutrition ; 27(5): 534-42, 2011 May.
Artículo en Inglés | MEDLINE | ID: mdl-20739146

RESUMEN

OBJECTIVE: To determine if the Geriatric Nutritional Risk Index (GNRI), an index for the risk of nutrition-related complications, is associated with healthcare costs and risk of hospitalization at baseline and after 10 y. METHODS: Data from a German population-based cohort of 1999 subjects 55 to 74 y of age at baseline were used. Self-reported physician visits, length of hospital stay, and drug intake were used to estimate costs. The GNRI is based on serum albumin values and the discrepancy between real and ideal body weights. Low GNRI values were defined as mean minus 2 times standard deviation. Mean GNRI values were regarded as normal. RESULTS: Low baseline GNRI was consistently associated with increased total costs, probability of hospitalization, inpatient costs, and pharmaceutical costs at baseline and follow-up, after adjustment for socioeconomic characteristics, lifestyle factors, and coexisting conditions. Subjects with low GNRI at baseline had approximately 47% higher total costs, 50% higher risk of hospitalization, 62% higher inpatient costs and 27% higher pharmaceutical costs at follow-up than subjects with normal GNRI values. CONCLUSION: The GNRI risk predicted increased future healthcare costs and higher risk of hospitalization in independent-living older adults. The GNRI is a rapid and low-cost tool that might be routinely used in population-based settings.


Asunto(s)
Evaluación Geriátrica/métodos , Costos de la Atención en Salud/estadística & datos numéricos , Hospitalización/estadística & datos numéricos , Evaluación Nutricional , Anciano , Antropometría , Estudios Transversales , Fenómenos Fisiológicos Nutricionales del Anciano , Femenino , Estudios de Seguimiento , Hospitalización/economía , Humanos , Modelos Lineales , Modelos Logísticos , Masculino , Desnutrición/diagnóstico , Persona de Mediana Edad , Modelos Económicos , Estudios Prospectivos , Medición de Riesgo , Factores de Riesgo , Albúmina Sérica/análisis
20.
Econ Hum Biol ; 9(3): 302-15, 2011 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-21371953

RESUMEN

Obesity among children and adolescents is a growing public health burden. According to a national reference among German children and adolescents aged 3-17 years, 15% are overweight (including obese) and 6.3% are obese. This study aims to assess the economic burden associated with overweight and obesity in children based on a cross-sectional survey from two birth cohort studies: the GINI-plus - German Infant Nutritional Intervention plus Non-Intervention study (3287 respondents aged 9 to <12 years) and the LISA-plus study - Influence of life-style factors on the development of the immune system and allergies in East and West Germany (1762 respondents aged 9 to <12 years). Using a bottom-up approach, we analyse direct costs induced by the utilisation of healthcare services and indirect costs emerging from parents' productivity losses. To investigate the impact of Body Mass Index (BMI) on costs, we perform various descriptive analyses and estimate a two-part regression model. Average annual total direct medical costs of healthcare use are estimated to be €418 (95% CI [346-511]) per child, split between physician (22%), therapist (29%), hospital (41%) and inpatient rehabilitation costs (8%). Bivariate analysis shows considerable differences between BMI groups: €469 (severely underweight), €468 (underweight), €402 (normal weight), €468 (overweight) and €680 (obese). Indirect costs make up €101 per year on average and tend to be higher for obese children, although this was not statistically significant. Drawing on these results, differences in healthcare costs between BMI groups are already apparent in children.


Asunto(s)
Peso Corporal , Gastos en Salud , Niño , Estudios de Cohortes , Intervalos de Confianza , Costo de Enfermedad , Costos y Análisis de Costo/métodos , Femenino , Alemania , Humanos , Masculino , Oportunidad Relativa , Análisis de Regresión
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