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1.
Penetration of GSK1322322 into epithelial lining fluid and alveolar macrophages as determined by bronchoalveolar lavage.
Antimicrob Agents Chemother
; 58(1): 419-23, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24189245
2.
Safety, tolerability, and efficacy of GSK1322322 in the treatment of acute bacterial skin and skin structure infections.
Antimicrob Agents Chemother
; 58(11): 6518-27, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25136015
3.
Single-dose safety, tolerability, and pharmacokinetics of the antibiotic GSK1322322, a novel peptide deformylase inhibitor.
Antimicrob Agents Chemother
; 57(5): 2005-9, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23403431
4.
Effect of H2 blockade and food on single-dose pharmacokinetics of GSK1322322, a peptide deformylase inhibitor antibacterial.
Antimicrob Agents Chemother
; 57(6): 2556-61, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23529727
5.
Pharmacokinetics of zanamivir following intravenous administration to subjects with and without renal impairment.
Antimicrob Agents Chemother
; 57(7): 2967-71, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23587959
6.
Safety, tolerability and pharmacokinetics of repeat dosing of the antibiotic GSK1322322, a peptide deformylase inhibitor: a randomized placebo-controlled study.
J Antimicrob Chemother
; 68(8): 1901-9, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23557930
7.
The Effect of Food and Formulation on the Pharmacokinetics, Safety, and Tolerability of GSK1322322 in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 4(1): 49-55, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26097792
8.
Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment.
J Clin Pharmacol
; 55(9): 1042-50, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25857714
9.
Effects of omeprazole and ritonavir on absorption and elimination of the hepatitis C virus NS5A inhibitor GSK2336805 in healthy adults.
Clin Pharmacol Drug Dev
; 3(5): 338-45, 2014 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27129005
10.
Safety, tolerability and pharmacokinetics of orally inhaled zanamivir: a randomized study comparing Rotacap/Rotahaler and Rotadisk/Diskhaler in healthy adults.
Antivir Ther
; 18(6): 827-30, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23696221
11.
Safety, tolerability, and pharmacokinetics of oral and intravenous administration of GSK1322322, a peptide deformylase inhibitor.
J Clin Pharmacol
; 53(11): 1168-76, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23907665
12.
Ritonavir increases plasma amprenavir (APV) exposure to a similar extent when coadministered with either fosamprenavir or APV.
Antimicrob Agents Chemother
; 50(4): 1578-80, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16569890
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