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1.
Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254.
Clin Infect Dis
; 75(5): 786-794, 2022 09 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34996113
2.
Lack of pharmacokinetic interaction between the HIV-1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women.
Br J Clin Pharmacol
; 88(4): 1704-1712, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34427938
3.
A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33753329
4.
Phase I evaluation of pharmacokinetics and tolerability of the HIV-1 maturation inhibitor GSK3640254 and dolutegravir in healthy adults.
Br J Clin Pharmacol
; 87(9): 3501-3507, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33533507
5.
Multiple network-constrained regressions expand insights into influenza vaccination responses.
Bioinformatics
; 33(14): i208-i216, 2017 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28881994
6.
Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults.
J Infect Dis
; 211(7): 1174-84, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25367297
7.
Relative Bioavailability and Food Effect of GSK3640254 Tablet and Capsule Formulations in Healthy Participants.
Clin Pharmacol Drug Dev
; 11(5): 632-639, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34995417
8.
Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults.
Aging Cell
; 21(9): e13682, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35996998
9.
Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next-generation HIV-1 maturation inhibitor.
Pharmacol Res Perspect
; 8(6): e00671, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33200887
10.
Pandemic influenza H1N1 2009, innate immunity, and the impact of immunosenescence on influenza vaccine.
Yale J Biol Med
; 82(4): 143-51, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20027279
11.
Viral Drug Resistance Through 48 Weeks, in a Phase 2b, Randomized, Controlled Trial of the HIV-1 Attachment Inhibitor Prodrug, Fostemsavir.
J Acquir Immune Defic Syndr
; 77(3): 299-307, 2018 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29206721
12.
Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial.
PLoS One
; 13(10): e0205368, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30352054
13.
Safety and efficacy of the HIV-1 attachment inhibitor prodrug fostemsavir in antiretroviral-experienced subjects: week 48 analysis of AI438011, a Phase IIb, randomized controlled trial.
Antivir Ther
; 22(3): 215-223, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-27922453
14.
Efficacy, safety, bone and metabolic effects of HIV nucleoside reverse transcriptase inhibitor BMS-986001 (AI467003): a phase 2b randomised, controlled, partly blinded trial.
Lancet HIV
; 3(1): e13-22, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26762988
15.
Multicolor Digital Flow Cytometry in Human Translational Immunology.
Methods Mol Biol
; 1343: 53-64, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26420708
16.
Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination.
Aging (Albany NY)
; 7(1): 38-52, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25596819
17.
Safety and efficacy of the HIV-1 attachment inhibitor prodrug BMS-663068 in treatment-experienced individuals: 24 week results of AI438011, a phase 2b, randomised controlled trial.
Lancet HIV
; 2(10): e427-37, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26423650
18.
Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis.
J Int AIDS Soc
; 17(4 Suppl 3): 19530, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25394039
19.
Top3ß is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.
Nat Neurosci
; 16(9): 1238-47, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23912945
20.
Dysregulation of human Toll-like receptor function in aging.
Ageing Res Rev
; 10(3): 346-53, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21074638
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