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1.
Phys Rev E ; 98(1-1): 012311, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30110730

RESUMEN

The two-step contagion model is a simple toy model for understanding pandemic outbreaks that occur in the real world. The model takes into account that a susceptible person either gets immediately infected or weakened when getting into contact with an infectious one. As the number of weakened people increases, they eventually can become infected in a short time period and a pandemic outbreak occurs. The time required to reach such a pandemic outbreak allows for intervention and is often called golden time. Understanding the size-dependence of the golden time is useful for controlling pandemic outbreak. Using an approach based on a nonlinear mapping, here we find that there exist two types of golden times in the two-step contagion model, which scale as O(N^{1/3}) and O(N^{ζ}) with the system size N on Erdos-Rényi networks, where the measured ζ is slightly larger than 1/4. They are distinguished by the initial number of infected nodes, o(N) and O(N), respectively. While the exponent 1/3 of the N-dependence of the golden time is universal even in other models showing discontinuous transitions induced by cascading dynamics, the measured ζ exponents are all close to 1/4 but show model-dependence. It remains open whether or not ζ reduces to 1/4 in the asymptotically large-N limit. Our method can be applied to several models showing a hybrid percolation transition and gives insight into the origin of the two golden times.


Asunto(s)
Enfermedades Transmisibles/epidemiología , Modelos Teóricos , Enfermedades Transmisibles/transmisión , Simulación por Computador , Susceptibilidad a Enfermedades , Humanos , Dinámicas no Lineales
2.
Phys Rev E Stat Nonlin Soft Matter Phys ; 75(1 Pt 1): 011302, 2007 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-17358140

RESUMEN

In a realistic three-dimensional setup, we simulate the slow deformation of idealized granular media composed of spheres undergoing an axisymmetric triaxial shear test. We follow the self-organization of the spontaneous strain localization process leading to a shear band and demonstrate the existence of a critical packing density inside this failure zone. The asymptotic criticality arising from the dynamic equilibrium of dilation and compaction is found to be restricted to the shear band, while the density outside of it keeps the memory of the initial packing. The critical density of the shear band depends on friction (and grain geometry) and in the limit of infinite friction it defines a specific packing state, namely the dynamic random loose packing.

3.
Phys Rev E Stat Nonlin Soft Matter Phys ; 75(1 Pt 1): 011305, 2007 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-17358143

RESUMEN

We introduce a model to describe the wide shear zones observed in modified Couette cell experiments with granular material. The model is a generalization of the recently proposed approach based on a variational principle. The instantaneous shear band is identified with the surface that minimizes the dissipation in a random potential that is biased by the local velocity difference and pressure. The apparent shear zone is the ensemble average of the instantaneous shear bands. The numerical simulation of this model matches excellently with experiments and has measurable predictions.

4.
Sci Rep ; 7(1): 5723, 2017 07 18.
Artículo en Inglés | MEDLINE | ID: mdl-28720828

RESUMEN

Hybrid percolation transitions (HPTs) induced by cascading processes have been observed in diverse complex systems such as k-core percolation, breakdown on interdependent networks and cooperative epidemic spreading models. Here we present the microscopic universal mechanism underlying those HPTs. We show that the discontinuity in the order parameter results from two steps: a durable critical branching (CB) and an explosive, supercritical (SC) process, the latter resulting from large loops inevitably present in finite size samples. In a random network of N nodes at the transition the CB process persists for O(N 1/3) time and the remaining nodes become vulnerable, which are then activated in the short SC process. This crossover mechanism and scaling behavior are universal for different HPT systems. Our result implies that the crossover time O(N 1/3) is a golden time, during which one needs to take actions to control and prevent the formation of a macroscopic cascade, e.g., a pandemic outbreak.

5.
Phys Rev E ; 95(2-1): 022314, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-28297881

RESUMEN

Most studies of disease spreading consider the underlying social network as obtained without the contagion, though epidemic influences people's willingness to contact others: A "friendly" contact may be turned to "unfriendly" to avoid infection. We study the susceptible-infected disease-spreading model on signed networks, in which each edge is associated with a positive or negative sign representing the friendly or unfriendly relation between its end nodes. In a signed network, according to Heider's theory, edge signs evolve such that finally a state of structural balance is achieved, corresponding to no frustration in physics terms. However, the danger of infection affects the evolution of its edge signs. To describe the coupled problem of the sign evolution and disease spreading, we generalize the notion of structural balance by taking into account the state of the nodes. We introduce an energy function and carry out Monte Carlo simulations on complete networks to test the energy landscape, where we find local minima corresponding to the so-called jammed states. We study the effect of the ratio of initial friendly to unfriendly connections on the propagation of disease. The steady state can be balanced or a jammed state such that a coexistence occurs between susceptible and infected nodes in the system.

6.
Phys Rev E Stat Nonlin Soft Matter Phys ; 74(3 Pt 1): 031303, 2006 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17025619

RESUMEN

We present numerical results on spontaneous symmetry breaking strain localization in axisymmetric triaxial shear tests of granular materials. We simulated shear band formation using the three-dimensional distinct element method with spherical particles. We demonstrate that the local shear intensity, the angular velocity of the grains, the coordination number, and the local void ratio are correlated and any of them can be used to identify shear bands; however, the latter two are less sensitive. The calculated shear band morphologies are in good agreement with those found experimentally. We show that boundary conditions play an important role. We discuss the formation mechanism of shear bands in the light of our observations and compare the results with experiments. At large strains, with enforced symmetry, we found strain hardening.

7.
Phys Rev E ; 93: 042109, 2016 04.
Artículo en Inglés | MEDLINE | ID: mdl-27176256

RESUMEN

Interdependent networks are more fragile under random attacks than simplex networks, because interlayer dependencies lead to cascading failures and finally to a sudden collapse. This is a hybrid phase transition (HPT), meaning that at the transition point the order parameter has a jump but there are also critical phenomena related to it. Here we study these phenomena on the Erdos-Rényi and the two-dimensional interdependent networks and show that the hybrid percolation transition exhibits two kinds of critical behaviors: divergence of the fluctuations of the order parameter and power-law size distribution of finite avalanches at a transition point. At the transition point global or "infinite" avalanches occur, while the finite ones have a power law size distribution; thus the avalanche statistics also has the nature of a HPT. The exponent ß_{m} of the order parameter is 1/2 under general conditions, while the value of the exponent γ_{m} characterizing the fluctuations of the order parameter depends on the system. The critical behavior of the finite avalanches can be described by another set of exponents, ß_{a} and γ_{a}. These two critical behaviors are coupled by a scaling law: 1-ß_{m}=γ_{a}.

8.
Phys Rev E Stat Nonlin Soft Matter Phys ; 71(6 Pt 1): 061303, 2005 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-16089731

RESUMEN

We performed computer simulations based on a two-dimensional distinct element method to study granular systems of magnetized spherical particles. We measured the angle of repose and the surface roughness of particle piles, and we studied the effect of magnetization on avalanching. We report linear dependence of both angle of repose and surface roughness on the ratio f of the magnetic dipole interaction and the gravitational force (interparticle force ratio). There is a difference in avalanche formation at small and at large interparticle force ratios. The transition is at f(c) approximately 7. For f < f(c) small vertical chains follow each other at short times (granular regime), while for f > f(c) the avalanches are typically formed by one single large particle-cluster (correlated regime). The transition is not sharp. We give plausible estimates for f(c) based on stability criteria.

9.
J Clin Epidemiol ; 42(3): 217-29, 1989.
Artículo en Inglés | MEDLINE | ID: mdl-2785165

RESUMEN

The self-reported family support and stress of 249 ambulatory adult patients, aged 18-49 years, were studied relative to their self-reported functional health. Support from family members was found to be related positively with emotional function. Stress from family members was associated negatively with symptom status, physical function, and emotional function. Patients' severity of illness was related negatively to their symptom status, physical function, and social function, but not to their emotional function. During the study a new self-report instrument, the Duke Social Support and Stress Scale (DUSOCS), was developed to measure family and non-family support and stress. Also, a new chart audit methodology, the Duke Severity of Illness Scale (DUSOI), was designed to assess severity in the ambulatory setting. Reliability and validity of the DUSOCS and the DUSOI were supported. The importance of the patient's perception of health and its family determinants is emphasized.


Asunto(s)
Actitud Frente a la Salud , Familia , Indicadores de Salud , Encuestas Epidemiológicas , Medio Social , Apoyo Social , Estrés Psicológico/psicología , Adolescente , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , North Carolina , Índice de Severidad de la Enfermedad , Encuestas y Cuestionarios
10.
Biomaterials ; 1(1): 27-9, 1980 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-6258659

RESUMEN

The reaction of methylglyoxal with polypeptides is accompanied by an electron spin resonance absorption in the free radial region. Analysing the interaction of methylglyoxal with poly-L-lysine we found that methylglyoxal polymer formation is a major process in our system. The electron spin resonance signal seems to originate both from the polymer itself and its interaction with the polypeptide. Nuclear magnetic resonance measurements show that the methylglyoxal polymer interacts with the polypeptide via the NH groups of peptide bonds.


Asunto(s)
Aldehídos , Péptidos , Polilisina , Piruvaldehído , Espectroscopía de Resonancia por Spin del Electrón , Lisina/análogos & derivados , Espectroscopía de Resonancia Magnética
11.
Phys Rev Lett ; 84(17): 3851-4, 2000 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-11019222

RESUMEN

We introduce a mesoscopic model for the formation and evolution of shear bands in loose granular media. Numerical simulations reveal that the system undergoes a nontrivial self-organization process which is governed by the motion of the shear band and the consequent restructuring of the material along it. High density regions are built up, progressively confining the shear bands in localized regions. This results in an inhomogeneous aging of the material with a very slow increase in the mean density, displaying an unusual glassylike system-size dependence.

12.
Clin Electroencephalogr ; 27(2): 95-9, 1996 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-8681469

RESUMEN

Brainstem auditory evoked potentials (BAEP) were recorded and correlated with the clinical and electroencephalographic (EEG) findings in three verified cases of Creutzfeldt-Jakob disease (CJD). In contrast to previous reports, there was progressive deterioration of the BAEPs, through initial asymmetry of wave latencies to abnormal wave morphology, and increased interpeak latencies. Consequently, in two of the patients, disorganization of the wave pattern and generalized conduction-time slowing appeared by the time there was a fully developed clinical picture of CJD with periodic EEG waves. In the third, clinically mild CJD, asymmetry of wave latencies in the BAEP emerged, correlating with the appearance of periodicity on EEG. Our findings are consistent with the late, progressive involvement of the brainstem by the pathological process in CJD.


Asunto(s)
Síndrome de Creutzfeldt-Jakob/fisiopatología , Potenciales Evocados Auditivos del Tronco Encefálico/fisiología , Muerte Encefálica/fisiopatología , Tronco Encefálico/fisiopatología , Corteza Cerebral/fisiopatología , Síndrome de Creutzfeldt-Jakob/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Examen Neurológico , Pruebas Neuropsicológicas
13.
Phys Rev E Stat Nonlin Soft Matter Phys ; 63(5 Pt 1): 051112, 2001 May.
Artículo en Inglés | MEDLINE | ID: mdl-11414892

RESUMEN

We consider a preferential growth model where particles are added one by one to the system consisting of clusters of particles. A new particle can either form a new cluster (with probability q) or join an already existing cluster with a probability proportional to the size thereof. We calculate exactly the probability Pi(k,t) that the size of the ith cluster at time t is k. We analyze the asymptotics, the scaling properties of the size distribution and of the mean size, as well as the relation of our system to recent network models.

14.
Phys Rev E Stat Nonlin Soft Matter Phys ; 66(2 Pt 2): 026125, 2002 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-12241255

RESUMEN

We study the time-dependent cross-correlations of stock returns, i.e., we measure the correlation as the function of the time shift between pairs of stock return time series using tick-by-tick data. We find a weak but significant effect showing that in many cases the maximum correlation appears at nonzero time shift, indicating directions of influence between the companies. Due to the weakness of this effect and the shortness of the characteristic time (of the order of a few minutes), our findings are compatible with market efficiency. The interaction of companies defines a directed network of influence.

15.
Phys Rev E Stat Nonlin Soft Matter Phys ; 64(5 Pt 2): 057105, 2001 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-11736146

RESUMEN

In this study we have carried out computer simulations of random walks on Watts-Strogatz-type small world networks and measured the mean number of visited sites and the return probabilities. These quantities were found to obey scaling behavior with intuitively reasoned exponents as long as the probability p of having a long range bond was sufficiently low.

16.
Phys Rev E Stat Nonlin Soft Matter Phys ; 63(1 Pt 2): 016107, 2001 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-11304314

RESUMEN

We consider open systems where cars move according to the deterministic Nagel-Schreckenberg rules [K. Nagel and M. Schreckenberg, J. Phys. I 2, 2221 (1992)] and with maximum velocity v(max)>1, which is an extension of the asymmetric exclusion process (ASEP). It turns out that the behavior of the system is dominated by two features: (a) the competition between the left and the right boundary, (b) the development of so-called "buffers" due to the hindrance that an injected car feels from the front car at the beginning of the system. As a consequence, there is a first-order phase transition between the free flow and the congested phase accompanied by the collapse of the buffers, and the phase diagram essentially differs from that for v(max)=1 (ASEP).

17.
Phys Rev E Stat Nonlin Soft Matter Phys ; 63(1 Pt 2): 016108, 2001 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-11304315

RESUMEN

We study the phases of the Nagel-Schreckenberg traffic model with open boundary conditions as a function of the randomization probabilities p>0 and the maximum velocity v(max)>1. Due to the existence of "buffer sites" which enhance the free-flow region, the behavior is much richer than that of the related, parallel updated asymmetric exclusion process [(ASEP), v(max)=1]. Such sites exist for v(max)> or =3 and pp(c) an additional maximum current phase separated by second-order transitions occurs like for the ASEP. The density profile decays in the maximum current phase algebraically with an exponent gamma approximately 2 / 3 for all v(max)> or =2 indicating that these models belong to another universality class than the ASEP where gamma=1 / 2.

18.
Phys Rev E Stat Nonlin Soft Matter Phys ; 68(4 Pt 1): 041102, 2003 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-14682918

RESUMEN

Based on theoretical results and simulations, in two-dimensional arrangements of a dense dipolar particle system, there are two relevant local dipole arrangements: (1) a ferromagnetic state with dipoles organized in a triangular lattice and (2) an antiferromagnetic state with dipoles organized in a square lattice. In order to accelerate simulation algorithms, we search for the possibility of cutting off the interaction potential. Simulations on a dipolar two-line system lead to the observation that the ferromagnetic state is much more sensitive to the interaction cutoff R than the corresponding antiferromagnetic state. For R approximately > 8 (measured in particle diameters) there is no substantial change in the energetical balance of the ferromagnetic and antiferromagnetic state and the ferromagnetic state slightly dominates over the antiferromagnetic state, while the situation is changed rapidly for lower interaction cutoff values, leading to the disappearance of the ferromagnetic ground state. We studied the effect of bending ferromagnetic and antiferromagnetic two-line systems and observed that the cutoff has a major impact on the energetical balance of the ferromagnetic and the antiferromagnetic state for R approximately < 4. Based on our results we argue that R approximately 5 is a reasonable choice for dipole-dipole interaction cutoff in two-dimensional dipolar hard sphere systems, if one is interested in local ordering.

19.
Phys Rev E Stat Nonlin Soft Matter Phys ; 68(5 Pt 2): 056110, 2003 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-14682849

RESUMEN

The time dependence of the recently introduced minimum spanning tree description of correlations between stocks, called the "asset tree" has been studied in order to reflect the financial market taxonomy. The nodes of the tree are identified with stocks and the distance between them is a unique function of the corresponding element of the correlation matrix. By using the concept of a central vertex, chosen as the most strongly connected node of the tree, an important characteristic is defined by the mean occupation layer. During crashes, due to the strong global correlation in the market, the tree shrinks topologically, and this is shown by a low value of the mean occupation layer. The tree seems to have a scale-free structure where the scaling exponent of the degree distribution is different for "business as usual" and "crash" periods. The basic structure of the tree topology is very robust with respect to time. We also point out that the diversification aspect of portfolio optimization results in the fact that the assets of the classic Markowitz portfolio are always located on the outer leaves of the tree. Technical aspects such as the window size dependence of the investigated quantities are also discussed.

20.
Phys Rev E Stat Nonlin Soft Matter Phys ; 65(6 Pt 1): 061305, 2002 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-12188714

RESUMEN

The systematic errors due to the practical implementation of the contact dynamics method for simulation of dense granular media are examined. It is shown that, using the usual iterative solver to simulate a chain of rigid particles, effective elasticity and sound propagation with a finite velocity occur. The characteristics of these phenomena are investigated analytically and numerically in order to assess the limits of applicability of this simulation method and to compare it with soft particle molecular dynamics.

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