Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 30
Filtrar
Más filtros

Banco de datos
País/Región como asunto
Tipo del documento
Intervalo de año de publicación
1.
J Neurovirol ; 26(5): 797-799, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32720233

RESUMEN

There is concern that the global burden of coronavirus disease of 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection might yield an increased occurrence of Guillain-Barré syndrome (GBS). It is currently unknown whether concomitant SARS-CoV-2 infection and GBS are pathophysiologically related, what biomarkers are useful for diagnosis, and what is the optimal treatment given the medical comorbidities, complications, and simultaneous infection. We report a patient who developed severe GBS following SARS-CoV-2 infection at the peak of the initial COVID-19 surge (April 2020) in New York City and discuss diagnostic and management issues and complications that may warrant special consideration in similar patients.


Asunto(s)
Betacoronavirus/patogenicidad , Infecciones por Coronavirus/complicaciones , Síndrome de Guillain-Barré/complicaciones , Hiponatremia/complicaciones , Neumonía Viral/complicaciones , Enfermedad Aguda , Anciano , Anticoagulantes/uso terapéutico , COVID-19 , Infecciones por Coronavirus/patología , Infecciones por Coronavirus/terapia , Infecciones por Coronavirus/virología , Progresión de la Enfermedad , Enoxaparina/uso terapéutico , Femenino , Síndrome de Guillain-Barré/patología , Síndrome de Guillain-Barré/terapia , Síndrome de Guillain-Barré/virología , Humanos , Hiponatremia/patología , Hiponatremia/terapia , Hiponatremia/virología , Ciudad de Nueva York , Pandemias , Plasmaféresis , Neumonía Viral/patología , Neumonía Viral/terapia , Neumonía Viral/virología , SARS-CoV-2
2.
World J Surg ; 43(12): 3027-3034, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31555867

RESUMEN

BACKGROUND: Adhesive small bowel obstruction (ASBO) severity has been associated with important clinical outcomes. However, the impact of ASBO severity on hospitalization cost is unknown. The American Association for the Surgery of Trauma (AAST) developed an Emergency General Surgery (EGS) disease severity grading system for ASBO. We stratified patients' ASBO severity and captured hospitalization costs hypothesizing that increased disease severity would correlate with greater costs. METHODS: This was a single-center study of hospitalized adult patients with SBO during 2015-2017. Clinical data and estimated total cost (direct + indirect) were abstracted. AAST EGS grades (I-IV) stratified disease severity. Costs were normalized to the median grade I cost. Univariate and multivariate analyses evaluated the relationship between normalized cost and AAST EGS grade, length of hospital and ICU stay, operative time, and Charlson comorbidity index. RESULTS: There were 214 patients; 119 (56%) were female. AAST EGS grades included: I (62%, n = 132), II (23%, n = 49), III (7%, n = 16), and IV (8%, n = 17). Relative to grade I, median normalized cost increased by 1.4-fold for grade II, 1.6-fold for grade III, and 4.3-fold for grade IV disease. No considerable differences in patient comorbidity between grades were observed. Pair-wise comparisons demonstrated that grade I disease cost less than higher grades (corrected p < 0.001). Non-operative management was associated with lower normalized cost compared to operative management (1.1 vs. 4.5, p < 0.0001). In patients who failed non-operative management, normalized cost was increased 7.2-fold. Collectively, the AAST EGS grade correlated well with cost (Spearman's p = 0.7, p < 0.0001). After adjustment for covariates, AAST EGS grade maintained a persistent relationship with cost. CONCLUSION: Increasing ASBO severity is independently associated with greater costs. Efforts to identify and mitigate costs associated with this burdensome disease are warranted. LEVEL OF EVIDENCE: III, economic/decision.


Asunto(s)
Costos de Hospital/estadística & datos numéricos , Obstrucción Intestinal/economía , Intestino Delgado/cirugía , Adherencias Tisulares/economía , Anciano , Urgencias Médicas , Servicio de Urgencia en Hospital , Femenino , Hospitalización/economía , Humanos , Obstrucción Intestinal/terapia , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Adherencias Tisulares/terapia , Estados Unidos
3.
Am J Emerg Med ; 36(1): 114-119, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28927951

RESUMEN

BACKGROUND: Prehospital airway management increasingly involves supraglottic airway insertion and a paucity of data evaluates outcomes in trauma populations. We aim to describe definitive airway management in traumatically injured patients who necessitated prehospital supraglottic airway insertion. METHODS: We performed a single institution retrospective review of multisystem injured patients (≥15years) that received prehospital supraglottic airway insertion during 2009 to 2016. Baseline demographics, number and type of: supraglottic airway insertion attempts, definitive airway and complications were recorded. Primary outcome was need for tracheostomy. Univariate and multivariable statistics were performed. RESULTS: 56 patients met inclusion criteria and were reviewed, 78% were male. Median age [IQR] was 36 [24-56] years. Injuries comprised blunt (94%), penetrating (4%) and burns (2%). Median ISS was 26 [22-41]. Median number of prehospital endotracheal intubation (PETI) attempts was 2 [1-3]. Definitive airway management included: (n=20, 36%, tracheostomy), (n=10, 18%, direct laryngoscopy), (n=6, 11%, bougie), (n=9, 15%, Glidescope), (n=11, 20%, bronchoscopic assistance). 24-hour mortality was 41%. Increasing number of PETI was associated with increasing facial injury. On regression, increasing cervical and facial injury patterns as well as number of PETI were associated with definitive airway control via surgical tracheostomy. CONCLUSIONS: After supraglottic airway insertion, operative or non-operative approaches can be utilized to obtain a definitive airway. Patients with increased craniofacial injuries have an increased risk for airway complications and need for tracheostomy. We used these factors to generate an evidence based algorithm that requires prospective validation. LEVEL OF EVIDENCE: Level IV - Retrospective study. STUDY TYPE: Retrospective single institution study.


Asunto(s)
Servicios Médicos de Urgencia/métodos , Intubación Intratraqueal , Laringoscopía/estadística & datos numéricos , Traqueostomía/estadística & datos numéricos , Heridas y Lesiones/mortalidad , Heridas y Lesiones/terapia , Adulto , Algoritmos , Traumatismos Faciales/etiología , Femenino , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Estudios Retrospectivos , Estados Unidos , Heridas y Lesiones/clasificación , Adulto Joven
4.
J Emerg Med ; 53(1): 110-115, 2017 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-28408233

RESUMEN

BACKGROUND: Quality-improvement efforts at our institution have identified chest tube dislodgement as a preventable complication of tube thoracostomy. Because proper fixation techniques are not well described in the literature and are seldom formally taught, techniques vary among residents. OBJECTIVE: Our aim was to develop and test a framework for teaching and assessing chest tube securement. METHODS: A repeated-measures study design was used. At baseline, 19 emergency medicine residents (program years 1-3) placed and secured a chest tube in a cadaver. After a 45-min proficiency-based teaching session using a low-cost chest tube simulator (approximate cost, $5), each resident again placed and secured a chest tube in a cadaver, followed by 3-month retention testing. All securements were evaluated by two raters using a four-point checklist and a five-point global assessment scale (GAS). The checklist addressed suture selection, tying knots down to the tube, wound approximation, and tube displacement relative to skin. RESULTS: After the initial educational intervention, median scores for the group improved significantly over baseline for the GAS (p < 0.001), checklist (p < 0.001), and amount of displacement (p = 0.01). At 3 months, GAS, checklist, and displacement scores did not differ significantly from the immediate post-test scores. Inter-rater reliability was substantial, with weighted κ values of .77 for the GAS and .70 for the checklist. CONCLUSIONS: Quality of chest tube securement by emergency medicine residents can be significantly improved with an inexpensive chest tube simulator and a brief workshop. The four-point checklist served as a reliable and effective means for teaching and assessing chest tube securement.


Asunto(s)
Tubos Torácicos , Competencia Clínica/normas , Medicina de Emergencia/educación , Enseñanza/normas , Competencia Clínica/estadística & datos numéricos , Evaluación Educacional , Medicina de Emergencia/estadística & datos numéricos , Humanos , Simulación de Paciente , Mejoramiento de la Calidad/estadística & datos numéricos
5.
World J Surg ; 40(1): 236-41, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26374224

RESUMEN

BACKGROUND: Rib fractures are common after chest wall trauma. For patients with flail chest, surgical stabilization is a promising technique for reducing morbidity. Anatomical difficulties often lead to an inability to completely repair the flail chest; thus, the result is partial flail chest stabilization (PFS). We hypothesized that patients with PFS have outcomes similar to those undergoing complete flail chest stabilization (CFS). METHODS: A prospectively collected database of all patients who underwent rib fracture stabilization procedures from August 2009 until February 2013 was reviewed. Abstracted data included procedural and complication data, extent of stabilization, and pulmonary function test results. RESULTS: Of 43 patients who underwent operative stabilization of flail chest, 23 (53%) had CFS and 20 (47%) underwent PFS. Anterior location of the fracture was the most common reason for PFS (45%). Age, sex, operative time, pneumonia, intensive care unit and hospital length of stay, and narcotic use were the same in both groups. Total lung capacity was significantly improved in the CFS group at 3 months. No chest wall deformity was appreciated on follow-up, and no patients underwent additional stabilization procedures following PFS. CONCLUSION: Despite advances in surgical technique, not all fractures are amenable to repair. There was no difference in chest wall deformity, narcotic use, or clinically significant impairment in pulmonary function tests among patients who underwent PFS compared with CFS. Our data suggest that PFS is an acceptable strategy and that extending or creating additional incisions for CFS is unnecessary.


Asunto(s)
Tórax Paradójico/cirugía , Fijación Interna de Fracturas/métodos , Fracturas de las Costillas/cirugía , Adulto , Femenino , Tórax Paradójico/diagnóstico por imagen , Tórax Paradójico/etiología , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Respiración Artificial , Pruebas de Función Respiratoria , Fracturas de las Costillas/complicaciones , Fracturas de las Costillas/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
6.
World J Surg ; 39(3): 789-93, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25403887

RESUMEN

BACKGROUND: Rib fracture stabilization has become a more accepted practice although stabilization of the most cephalad ribs presents a unique challenge. We present our experience with use of a 90° drill and screwdriver to bridge these difficult rib fractures. METHODS: This retrospective review included patients who underwent rib fracture stabilization from August 1, 2009, through September 30, 2012. Patients were divided into two groups: those whose procedure used the 90° device and those that did not. Data were compared using standard statistical analysis and reported as percentages and medians [interquartile ranges]. P values <0.05 were considered significant. RESULTS: We identified 89 patients: 29 (33%) had 90° devices used and 60 (67%) did not. There were no differences between groups in age, sex, Trauma-Related Injury Severity Score, the presence of flail chest, occurrence of pneumonia, and intensive care unit or hospital length of stay. The Injury Severity Score was higher in the 90° group (22 vs. 16; P = 0.03). The highest rib stabilized was different between the 2 groups (3 [2-5] vs. 5 [2-9]; P = 0.001), with more third rib stabilizations in the 90° group (38 vs. 20%; P = 0.04) as well as more total number of ribs fixed (5 vs. 4; P = 0.001). There was no difference in operative time between the 2 groups. CONCLUSIONS: The surgical reach for rib fracture stabilization has been extended with use of a 90° drill and screwdriver. High fractures under the scapula where access is technically challenging can be stabilized without prolonging operative times.


Asunto(s)
Fijación Interna de Fracturas/instrumentación , Fracturas de las Costillas/cirugía , Anciano , Tornillos Óseos , Femenino , Humanos , Puntaje de Gravedad del Traumatismo , Masculino , Persona de Mediana Edad , Tempo Operativo , Estudios Retrospectivos
7.
Surgery ; 171(6): 1665-1670, 2022 06.
Artículo en Inglés | MEDLINE | ID: mdl-34815095

RESUMEN

BACKGROUND: Small bowel obstruction management has evolved to incorporate the Gastrografin challenge. We expanded its use to the emergency department observation unit, potentially avoiding hospital admission for highly select small bowel obstruction patients. We hypothesized that the emergency department observation unit small bowel obstruction protocol would reduce admissions, costs, and the total time spent in the hospital without compromising outcomes. METHODS: We reviewed patients who presented with small bowel obstruction from January 2015 to December 2018. Patients deemed to require urgent surgical intervention were admitted directly and excluded. The emergency department observation unit small bowel obstruction guidelines were introduced in November 2016. Patients were divided into pre and postintervention groups based on this date. The postintervention group was further subclassified to examine the emergency department observation unit patients. Cost analysis for each patient was performed looking at number of charges, direct costs, indirect cost, and total costs during their admission. RESULTS: In total, 125 patients were included (mean age 69 ± 14.3 years). The preintervention group (n = 62) and postintervention group (n = 63) had no significant difference in demographics. The postintervention group had a 51% (36.7 hours, P < .001) reduction in median duration of stay and a total cost reduction of 49% (P < .001). The emergency department observation unit subgroup (n = 46) median length of stay was 23.6 hours. The readmission rate was 16% preintervention compared to 8% in the postintervention group (P = .18). CONCLUSION: Management of highly selected small bowel obstruction patients with the emergency department observation unit small bowel obstruction protocol was associated with decreased length of stay and total cost, without an increase in complications, surgical intervention, or readmissions.


Asunto(s)
Obstrucción Intestinal , Anciano , Anciano de 80 o más Años , Diatrizoato de Meglumina , Servicio de Urgencia en Hospital , Hospitales , Humanos , Obstrucción Intestinal/etiología , Obstrucción Intestinal/cirugía , Tiempo de Internación , Persona de Mediana Edad , Estudios Retrospectivos
8.
J Trauma Acute Care Surg ; 91(6): 947-950, 2021 12 01.
Artículo en Inglés | MEDLINE | ID: mdl-34407006

RESUMEN

BACKGROUND: Rib fractures are uncommon in children and are markers of extreme traumatic force from high-energy or nonaccidental etiology. Traditional care includes nonoperative management, with analgesia, ventilator support, and pulmonary physiotherapy. Surgical stabilization of rib fractures (SSRFs) has been associated with improved outcomes in adults. In children, SSRF is performed and its role remains unclear, with data only available from case reports. We created a collected case series of published pediatric SSRF cases, with the aim to provide a descriptive summary of the existing data. METHODS: Published cases of SSRF following thoracic trauma in patients younger than 18 years were identified. Collected data included demographics, injury mechanism, associated injuries, surgical indication(s), surgical technique, time to extubation, postoperative hospital stay, and postoperative follow-up. RESULTS: Six cases were identified. All were boys, with age range 6 to 16 years. Injury mechanism was high-energy blunt force in all cases, and all patients suffered multiple associated injuries. Five of six cases were related to motor vehicles, and one was horse-related. Indication(s) for surgery included ventilator dependence in five, significant chest deformity in two, and poor pain control in one case. Plating systems were used for rib stabilization in five of six cases, while intramedullary splint was used in one. All patients were extubated within 7 days following SSRF, and all were discharged by postoperative Day 20. On postoperative follow-up, no SSRF-related major issues were reported. One patient underwent hardware removal at 2 months. CONCLUSION: Surgical stabilization of rib fractures in children is safe and feasible, and should be considered as an alternative to nonoperative therapy in select pediatric thoracic trauma cases. Potential indications for SSRF in pediatric patients include poor pain control, chest wall deformity, or ventilator dependence. Further studies are needed to establish the role and possible benefits of SSRF in pediatric thoracic trauma. LEVEL OF EVIDENCE: Collected case series, level V.


Asunto(s)
Fijación de Fractura/métodos , Adolescente , Cuidados Posteriores/métodos , Cuidados Posteriores/estadística & datos numéricos , Extubación Traqueal/métodos , Extubación Traqueal/estadística & datos numéricos , Niño , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Evaluación de Procesos y Resultados en Atención de Salud , Selección de Paciente , Periodo Preoperatorio , Fracturas de las Costillas/diagnóstico , Fracturas de las Costillas/etiología , Fracturas de las Costillas/fisiopatología , Fracturas de las Costillas/cirugía , Traumatismos Torácicos/diagnóstico , Traumatismos Torácicos/etiología , Traumatismos Torácicos/cirugía , Índices de Gravedad del Trauma , Heridas no Penetrantes/complicaciones
9.
Eur Radiol Exp ; 5(1): 9, 2021 02 16.
Artículo en Inglés | MEDLINE | ID: mdl-33590301

RESUMEN

BACKGROUND: Rib fractures are associated with considerable morbidity and mortality. Surgical stabilization of rib fractures (SSRF) can be performed to mitigate complications. Sarcopenia is in general known to be associated with poor clinical outcomes. We investigated if sarcopenia impacted number of days of mechanical ventilation, intensive care unit (ICU) stay, and total hospital stay in patients who underwent SSRF. METHODS: A retrospective single institutional review was performed including patients who underwent SSRF (2009-2017). Skeletal muscle index (SMI) was semiautomatically calculated at the L3 spinal level on computed tomography (CT) images and normalized by patient height. Sarcopenia was defined as SMI < 55 cm2/m2 in males and < 39 cm2/m2 in females. Demographics, operative details, and postoperative outcomes were reviewed. Univariate and multivariate analyses were performed. RESULTS: Of 238 patients, 88 (36.9%) had sarcopenia. There was no significant difference in number of days of mechanical ventilation (2.8 ± 4.9 versus 3.1 ± 4.3, p = 0.304), ICU stay (5.9 ± 6.5 versus 4.9 ± 5.7 days, p = 0.146), or total hospital stay (13.3 ± 7.2 versus 12.9 ± 8.2 days, p = 0.183) between sarcopenic and nonsarcopenic patients. Sarcopenic patients demonstrated increased modified frailty index scores (1.5 ± 1.1 versus 0.9 ± 0.9, p < 0.001) compared to nonsarcopenic patients. CONCLUSIONS: For patients who underwent SSRF for rib fractures, sarcopenia did not increase the number of days of mechanical ventilation, ICU stay, or total hospital stay. Sarcopenia should not preclude the utilization of SSRF in these patients.


Asunto(s)
Fracturas de las Costillas , Sarcopenia , Femenino , Humanos , Tiempo de Internación , Masculino , Estudios Retrospectivos , Fracturas de las Costillas/diagnóstico por imagen , Fracturas de las Costillas/cirugía , Sarcopenia/diagnóstico por imagen , Tomografía Computarizada por Rayos X
10.
Am J Surg ; 218(3): 521-526, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-30885455

RESUMEN

INTRODUCTION: Surgical exploration is still considered mandatory in the setting of small bowel obstruction (SBO) and a virgin abdomen by some large centers. The aim of this study is to determine the etiology of SBO in patients without prior abdominal operation. METHODS: Retrospective review of the patients treated for SBO and virgin abdomen at the Mayo Clinic between 2006 and 2016 was performed. Follow up data, operative and pathologic findings were examined to determine the etiology of SBO. RESULTS: Sixty patients met inclusion criteria; abdominal exploration was performed in 50 patients (83%) and 10 patients (17%) were managed non-operatively. Exploration was therapeutic in 29 (58%), negative in 20 (40%) and non-therapeutic in one patient (2%). Overall, 8 patients (13%) were diagnosed with a malignancy: right-sided colon cancer (n = 3), small bowel (SB) neuroendocrine tumor (n = 2), SB lymphoma (n = 2) and carcinomatosis peritonei (n = 1); Upon retrospective review, both SB neuroendocrine tumors and one SB lymphoma were visible on the initial imaging. Leukocytosis (p = .03) and no recent weight loss (p = .04) were associated with negative exploration. CONCLUSION: Patients with SBO and virgin abdomen frequently have a benign etiology. Careful imaging review directed at subtle signs of an underlying malignancy is warranted. If non-operative management is chosen, close follow up is essential and it should include a careful personal and family history as well as updated colonoscopy.


Asunto(s)
Obstrucción Intestinal/etiología , Intestino Delgado , Abdomen/cirugía , Anciano , Femenino , Humanos , Obstrucción Intestinal/diagnóstico , Obstrucción Intestinal/cirugía , Laparotomía , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
11.
BMJ Case Rep ; 12(8)2019 Aug 28.
Artículo en Inglés | MEDLINE | ID: mdl-31466980

RESUMEN

Ectopic branches of the external carotid artery are rare but have critical diagnostic and therapeutic implications. We present a case involving a 70-year-old man who presented with recurrent left hemispheric strokes in the setting of a subocclusive left internal carotid stenosis. A left ascending pharyngeal artery with variant origin from the internal carotid artery helped maintain flow distal to the area of stenosis and allowed for safe and successful internal carotid artery stenting. Identification of this variant and recognition of the anastomotic network involving this connection were crucial to determine the safety of stenting. The patient had no further recurrent events and had sustained improvement on his 90-day follow-up.


Asunto(s)
Variación Anatómica/fisiología , Arteria Carótida Interna/patología , Estenosis Carotídea/patología , Faringe/irrigación sanguínea , Anciano , Angioplastia de Balón/instrumentación , Arterias/fisiología , Arteria Carótida Externa/fisiología , Arteria Carótida Interna/diagnóstico por imagen , Arteria Carótida Interna/fisiopatología , Estenosis Carotídea/diagnóstico por imagen , Estenosis Carotídea/terapia , Circulación Cerebrovascular/fisiología , Circulación Colateral/fisiología , Angiografía por Tomografía Computarizada/métodos , Constricción Patológica/terapia , Humanos , Masculino , Recurrencia , Stents , Accidente Cerebrovascular/diagnóstico , Accidente Cerebrovascular/etiología , Resultado del Tratamiento
12.
Surgery ; 166(4): 556-563, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31378483

RESUMEN

OBJECTIVES: To determine the long-term impact of vaccination on any postoperative infection in adults who underwent splenectomy. METHODS: All adults (≥18 years) who underwent splenectomy from 1965 to 2011 in Olmsted County, MN were identified using the Rochester Epidemiology Project. Descriptive statistics, Kaplan-Meier estimates, and Cox proportional hazard ratios were performed. RESULTS: There were 724 patients who underwent splenectomy; 47% were female with a median age of 55 (35-69) years. Overall vaccination rate (pneumococcal, H influenza, meningococcal) was 62% (n = 449). There were 268 (36%) patients who developed a post-splenectomy infection; most presented with sepsis 148 (55%). The 3 most common infections included pneumonia (124, 17%), bloodstream (67, 9%), and urinary tract infection (49, 7%). Median time to infection was quicker in non-vaccinated compared with vaccinated patients (1.5 [0.1-4.3] vs 3.3 [1.9-9.8] years, P = .01). CONCLUSION: In this population-based study, the highest risk of infection after splenectomy was in patients who did not receive complete vaccination. Lack of complete vaccination was associated with a reduced time to infection and increased rates of bloodstream infections at 5 years. Infectious complication risk reduced as vaccination protocols improved for all indications except for malignancy. Adults who underwent a splenectomy should continue to receive booster vaccines.


Asunto(s)
Esplenectomía/efectos adversos , Infección de la Herida Quirúrgica/epidemiología , Infección de la Herida Quirúrgica/prevención & control , Vacunación/estadística & datos numéricos , Adulto , Factores de Edad , Anciano , Bases de Datos Factuales , Femenino , Humanos , Incidencia , Vacunas contra la Influenza/administración & dosificación , Estimación de Kaplan-Meier , Masculino , Vacunas Meningococicas/administración & dosificación , Persona de Mediana Edad , Minnesota , Vacunas Neumococicas/administración & dosificación , Modelos de Riesgos Proporcionales , Valores de Referencia , Estudios Retrospectivos , Medición de Riesgo , Factores Sexuales , Esplenectomía/métodos
13.
Am J Surg ; 218(5): 869-875, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-30857639

RESUMEN

BACKGROUND: Surgical stabilization of rib fractures (SSRF) can be used to improve pulmonary mechanics; however, hardware infection is a morbid complication. Antibiotic impregnated beads have been used to suppress infection in orthopedic practices. We aimed to determine the efficacy of antibiotic beads for infected and at-risk SSRF hardware. METHODS: This is a single institution retrospective review of adults (18 years or older) that received SSRF between 2009 and 2017. Infected and at-risk hardware were managed with antibiotic beads. The primary outcome was bony union of rib fractures. RESULTS: There were 285 SSRF patients. Infection rate was 3.5%. Antibiotic beads were placed in 17 patients - 9 for infected hardware and 8 for prophylaxis. Increased body mass index (p = 0.04) and hemorrhagic shock at admission (p = 0.03) were risk factors for infection. There was 100% bony union post-operatively. CONCLUSION: SSRF hardware infection is morbid. Antibiotic beads can salvage SSRF hardware until bony union.


Asunto(s)
Antibacterianos/administración & dosificación , Fijación Interna de Fracturas/instrumentación , Fijadores Internos/efectos adversos , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Fracturas de las Costillas/cirugía , Terapia Recuperativa/métodos , Infección de la Herida Quirúrgica/tratamiento farmacológico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Antibacterianos/uso terapéutico , Femenino , Estudios de Seguimiento , Humanos , Fijadores Internos/microbiología , Masculino , Persona de Mediana Edad , Infecciones Relacionadas con Prótesis/diagnóstico , Infecciones Relacionadas con Prótesis/epidemiología , Infecciones Relacionadas con Prótesis/prevención & control , Estudios Retrospectivos , Infección de la Herida Quirúrgica/diagnóstico , Infección de la Herida Quirúrgica/epidemiología , Infección de la Herida Quirúrgica/prevención & control , Resultado del Tratamiento , Adulto Joven
14.
Trauma Case Rep ; 22: 100218, 2019 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-31249855

RESUMEN

BACKGROUND: Three-dimensional printed models are increasingly used in many fields including medicine and surgery, but their use in the planning and execution of complex chest wall reconstruction has not been adequately described. In cases of non-union or prior attempts at chest wall reconstruction which have failed, there can be substantial deviations from expected chest wall anatomy. We report a novel technique for pre-operative planning and surgical execution of complex chest wall reconstruction, assisted by 3D printing. Our objective was to utilize 3-D volumetric modeling coupled with 3-D printing to produce patient-specific models for chest wall reconstruction in complex cases. METHODS: Soft tissue reconstruction 0.75 mm slice thickness computed tomography (CT) imaging data was loaded into medical CAD software for segmentation. Lung, muscle, foreign bodies, and bony structureswere separated due to the differences in density between them. The 3D volumetric mesh was then quality checked and stereolithography files (STL) were made which were able to be utilized by the 3D printer. The STL files were exported to a Objet 500 material jetting printer that utilized several UV light cured photopolymers. RESULTS: As an example case, we discuss a 55 year old male who underwent resuscitative thoracotomy. In the early post-operative period, he developed a pulmonary hernia in the 6th intercostal space, repaired with wire cerclage reapproximation of ribs. He developed a symptomatic mobile chest wall at the site of prior repair with additional concern for dissociated anterior cartilage. In preparation for operative repair, a 3D printed model was created, demonstrating fractured cartilage anteriorly as well a saw effect through the six and seventh ribs. An additional model was created using the normal ribs from the right side in mirror image reflection to quantify the degree and precise geometry of mal-alignment to the left chest. These models were then utilized to determine the operative approach via a thoracotomy incision to remove the cerclage wires, followed by parasternal incision, reduction and plating of the sternocostal non-union bursa Rib non-unions were plate stabilized. Repeat imaging in follow-up has demonstrated continued appropriate alignment and the patient reported improvement in his symptoms. CONCLUSION: At present, the cost of 3-D printing remains substantial, but given the improved planning in complex cases, this cost may be recaptured in the reduction of operative time and improved outcomes with reduced re-operation rates. We believe that the early adoption of this technology by surgeons can help improve surgical quality and provide enhanced individualized patient care. These patient-specific models facilitate identification of features which are often not detected with standard 3-D reconstructed CT rendering. Centers should pursue the integration of 3-D printed models into their practice and active collaborations between surgeons and modeling experts should be sought at every available opportunity.

15.
J Trauma Acute Care Surg ; 87(6): 1277-1281, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31107433

RESUMEN

BACKGROUND: Surgical stabilization of rib fractures (SSRF) is increasingly used for severe rib fractures/flail chest. There are no reports discussing mechanisms of failure of implanted hardware, its clinical presentation, or consequences. The purpose of this study was to evaluate the incidence, presenting signs, and clinical sequela of hardware failure after SSRF. METHODS: A multicenter, retrospective study was performed by a group of surgeons with a large SSRF case volume. All cases with known hardware failure from January 1, 2010, to December 31, 2017, were included. The surgeon's experience at the time of hardware implantation, specific implant used, number of failures the surgeon had experienced with the same system, and time from implantation to hardware failure were recorded. Additionally, patient demographics, including age, comorbid conditions, and number and location of rib fractures were recorded. Symptomatology associated with hardware failure and need for explant and/or reimplantation of hardware was also recorded. Nonparametric statistical tests were used to compare cohorts. RESULTS: Of 1,224 patients who underwent SSRF, 38 patients with 233 rib fractures and 279 fracture segments experienced hardware failure and were enrolled in the study. Twelve patients presented more than 3 months following injury. Median age was 54 years old and 34% were active smokers. One hundred forty-four plates were implanted with a median of four plates per patient. Median number of SSRF cases by each surgeon was 100 (range, 1-280). Fractures and hardware failure were most frequent in the anterolateral/lateral region. Hardware failure was mostly due to screw migration and plate fracture. Hardware failure was asymptomatic in 40% and presented as pain in 42% of cases. Fifty-five percent of the cases required explantation of hardware, and only 10% required SSRF again. There was no difference between the acute and chronic fracture cohorts. CONCLUSION: Hardware failure after SSRF is rare and often asymptomatic. When present, it rarely requires redo SSRF. LEVEL OF EVIDENCE: Therapeutic, level V.


Asunto(s)
Placas Óseas , Tornillos Óseos , Falla de Equipo , Fijación Interna de Fracturas/instrumentación , Fracturas de las Costillas/cirugía , Falla de Equipo/estadística & datos numéricos , Femenino , Migración de Cuerpo Extraño , Humanos , Masculino , Persona de Mediana Edad , Reoperación , Estudios Retrospectivos , Fracturas de las Costillas/complicaciones , Fumar/efectos adversos , Resultado del Tratamiento
16.
Hum Mov Sci ; 57: 171-177, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29241046

RESUMEN

Post activation potentiation (PAP) is a phenomenon in which muscular force is acutely enhanced as a result of prior contractile activity. The net augmentation is dependent upon the intensity of the preceding conditioning contraction influencing calcium release and phosphorylation of the regulatory myosin light chain. This phenomenon has been recorded after various types of conditioning contractions, however the interaction of a warmup on PAP remains uncertain and whether this differs between males and females requires consideration. We investigated the effect of a cycling warmup on twitch contractile properties and PAP of the plantar flexors on males and in females using oral contraceptives. A maximal voluntary contraction (MVC) of the plantar flexors preceded and followed a 10-min cycling warmup, where supramaximal twitches were administered prior to, during and after the conditioning contractions. Twitch contractile properties of peak tension (PT), time to peak tension (TPT), half relaxation time (HRT) and contraction duration (CD) were compared between resting and potentiated twitches before and after the warmup. Ultrasonography was used to measure in vivo Achilles tendon architecture. Males were ∼30% stronger, but voluntary activation did not differ from females (p = .37). In males and females PT increased following the conditioning MVC (p = .03). The degree of potentiation was higher following the warmup in females (25.01%, p = .02) but not males (p = .24). TPT, HRT and contraction duration (p < .05) were faster after the warmup and in males (p < .001). Achilles tendon elongation was unchanged by the warmup (p = .11). Ten minutes of a cycling warmup reduced TPT, HRT, and CD in both males and females without altering the tendon. The degree of PAP was higher in females than males following the warmup. This difference might be associated with altered calcium kinetics of females on oral contraceptives as well as higher proportion of type I fibres in the active muscles.


Asunto(s)
Tendón Calcáneo/fisiología , Ciclismo , Ejercicio Físico , Contracción Isométrica/fisiología , Músculo Esquelético/fisiología , Adulto , Anticonceptivos Orales , Estimulación Eléctrica , Electromiografía , Femenino , Humanos , Masculino , Fosforilación , Factores Sexuales , Adulto Joven
17.
Am Surg ; 84(6): 844-850, 2018 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-29981613

RESUMEN

Symptomatic rib nonunions are a rare complication after rib fractures. Methods used to address these nonunions range from pain management, rib resection, and rib fixation with plates and occasional autologous bone grafting. Given potential complications associated with rib resections such as pulmonary hernia, we hypothesized that plate fixation and autologous bone grafting would yield satisfactory long-term outcomes and a high union rate. Patients (aged ≥18 years) at a single institution with a symptomatic rib nonunion who underwent surgical rib stabilization of the nonunion coupled with bone autograft were evaluated (2010-2014). Pertinent clinical, operative, radiologic, and follow-up data were abstracted. Univariate analyses to assess the relationship of clinical outcomes were performed. Six patients underwent nonunion repair with autograft and plating. The mean time from injury to surgical repair of nonunion was 15 (±6.1) months. A median of 3 [1-3] ribs were repaired with surgery. Postoperative radiographic union was demonstrated on cross-sectional imaging at three months in four patients (57%) and in all patients at five months postoperatively. No patients developed postoperative pulmonary hernia during follow-up. All patients had a significant reduction in median patient-reported pain at follow-up. Surgical rib fixation and bone autograft can provide acceptable outcomes for patients with rib fracture nonunion. This method provides pain relief and promotes healing of the nonunion gap without pulmonary hernia development. Operative fixation and bone autograft should be considered as a viable technical alternative to resection alone for rib nonunion.


Asunto(s)
Placas Óseas , Trasplante Óseo , Fijación Interna de Fracturas/métodos , Fracturas no Consolidadas/cirugía , Fracturas de las Costillas/cirugía , Fijación Interna de Fracturas/instrumentación , Curación de Fractura , Fracturas no Consolidadas/diagnóstico por imagen , Fracturas no Consolidadas/etiología , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Trasplante Autólogo
18.
Ann Thorac Surg ; 104(6): e439-e441, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29153813

RESUMEN

When identified, rib fractures in children are associated with high-energy trauma, nonaccidental trauma, or both. Traditionally, the optimal management of rib fractures in children is supportive care. In this case report, we present a 6-year-old boy who underwent surgical rib fixation for multiple displaced and comminuted rib fractures after being stepped on by a horse.


Asunto(s)
Fijación Interna de Fracturas , Fracturas Conminutas/cirugía , Fracturas de las Costillas/cirugía , Heridas no Penetrantes/complicaciones , Niño , Fracturas Conminutas/diagnóstico por imagen , Fracturas Conminutas/etiología , Humanos , Masculino , Fracturas de las Costillas/diagnóstico por imagen , Fracturas de las Costillas/etiología , Heridas no Penetrantes/diagnóstico por imagen , Heridas no Penetrantes/terapia
19.
J Crit Care ; 42: 324-327, 2017 12.
Artículo en Inglés | MEDLINE | ID: mdl-28843860

RESUMEN

PURPOSE: Newly diagnosed swallowing dysfunction is rare, with an incidence <1% in hospitalized patients. The purpose of this study was to evaluate the incidence and clinical characteristics of dysphagia in elderly trauma patients specifically. METHODS: Patients ≥75years who had newly diagnosed swallowing dysfunction were identified by retrospective review of our institutional trauma database from 2009-2012. A comparison group without dysphagia was also identified that was matched by age, gender, injury mechanism, and injury severity score (ISS). Relevant demographics, injury characteristics, and potential factors associated with dysphagia were collected. RESULTS: 1323 patients met criteria. Of these, 56(4.2%) had newly identified dysphagia. Cases and controls were similar in regards to regional injury pattern (AIS). Patients with dysphagia had a mean Charlson Comorbidity Index (CCI) of 3.7 vs. 1.9 for patients without dysphagia (p<0.01). Patients with dysphagia also had longer hospital (11.4 vs. 5.8days, p<0.01) and ICU LOS (5.6 vs 1.9days, p<0.01). On multivariable regression, CCI greater than 3 (OR 7.2, p<0.001), in-hospital complications (OR 9.6, p<0.01), and ICU LOS greater than 2days (OR 1.5, p<0.05) were independently associated with the diagnosis of dysphagia. CONCLUSIONS: Elderly trauma patients with a high comorbidity burden or with prolonged ICU lengths of stay should be screened for dysphagia.


Asunto(s)
Trastornos de Deglución/epidemiología , Traumatismo Múltiple/complicaciones , Anciano , Anciano de 80 o más Años , Comorbilidad , Bases de Datos Factuales , Trastornos de Deglución/complicaciones , Trastornos de Deglución/diagnóstico , Servicio de Urgencia en Hospital , Femenino , Servicios de Salud para Ancianos , Humanos , Incidencia , Puntaje de Gravedad del Traumatismo , Tiempo de Internación , Masculino , Minnesota/epidemiología , Estudios Retrospectivos
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA