Can Asymmetry in Total Knee Arthroplasty Design Lead to More Normal-Like Postoperative Kinematics? A Multi-Implant Evaluation.

BACKGROUND: Few studies have evaluated the effects of symmetrical versus asymmetrical implant designs, more specifically the femoral condyles, trochlear groove, joint line, and bearing surfaces. The objective of this study was to investigate multiple posterior cruciate-retaining (PCR) total knee arthroplasty (TKA) designs influencing factors related to TKA asymmetry, and to investigate whether asymmetry can improve postoperative knee kinematics. METHODS: In vivo tibio-femoral kinematics for 99 subjects was evaluated in this retrospective study. Overall, 10 subjects had a nonimplanted, normal knee, and 89 subjects had 1 of 3 PCR TKAs with varying degrees of asymmetry within their femoral and tibial components (PCR #1 = 30, PCR #2 = 29, PCR #3 = 30). All TKAs were implanted by the same surgeon and were analyzed using fluoroscopy during a deep knee bend. RESULTS: At full extension, all 3 PCR TKAs experienced a more posteriorized position of the femoral condyles compared to the normal knee, with the 2 asymmetrical PCR TKAs experiencing more anteriorization compared to the third, symmetrical PCR TKA. Both the normal knee and the PCR TKA with greatest amount of asymmetry experienced statistically more posterior femoral rollback of the lateral condyle than the other 2 PCR TKAs. The PCR TKA with greater asymmetry also experienced statistically greater range of motion than the other 2 PCR TKAs. CONCLUSIONS: With increasing flexion, the design with the most asymmetry also experienced the most posterior femoral rollback, axial rotation, and greatest range of motion. The results in this study seem to suggest that the inclusion of asymmetry in a TKA could be beneficial for achieving more normal-like kinematics and greater weight-bearing knee flexion.

In Vivo Weight-Bearing Kinematics for Constrained Versus Traditional Bicruciate Stabilized Total Knee Arthroplasty Cohorts Compared to the Normal Knee.

BACKGROUND: Constrained inserts in total knee arthroplasty (TKA) may offer additional stability, but can this insert type allow unrestricted movements or will the extra conformity cause kinematic conflict with the cam-post mechanism in deeper flexion? The objective of this study was to evaluate the weight-bearing kinematics of both traditional and constrained bicruciate stabilized (BCS) TKA inserts to determine if the rollback induced by the cam-post mechanism will work in unison with the constrained polyethylene insert. METHODS: This study used previously published 3-dimensional model fitting techniques to compare weight-bearing flexion and femoro-tibial condylar motion patterns for 20 patients who had a traditional insert, 20 patients who had a constrained insert, and 10 previously published nonimplanted knees, all performing a deep knee bend activity while under fluoroscopic surveillance. RESULTS: The results from this study indicate that subjects having a bicruciate stabilized TKA experienced similar postoperative kinematics for both constrained and unconstrained insert options, comparable to normal knees. CONCLUSIONS: Subjects in this study having either a constrained or traditional insert experienced progressive rollback of both condyles, with the lateral condyle rolling more posterior than the medial condyle, leading to axial rotation. Although less in magnitude, these results were comparable to the normal knee in pattern, indicating that kinematic conflict did not occur for subjects having a constrained insert.

Effects of Posterior Tibial Slope on a Posterior Cruciate Retaining Total Knee Arthroplasty Kinematics and Kinetics.

BACKGROUND: It has been hypothesized that increasing posterior tibial slope can influence condylar rollback and play a role in increasing knee flexion. However, the effects of tibial slope on knee kinematics are not well studied. The objective of this study is to assess the effects of tibial slope on femorotibial kinematics and kinetics for a posterior cruciate retaining total knee arthroplasty design. METHODS: A validated forward solution model of the knee was implemented to predict the femorotibial biomechanics of a posterior cruciate retaining total knee arthroplasty with varied posterior slopes of 0°-8° at 2° intervals. All analyses were conducted on a weight-bearing deep knee bend activity. RESULTS: Increasing the tibial slope shifted the femoral component posteriorly at full extension but decreased the overall femoral rollback throughout flexion. With no tibial slope, the lateral condyle contacted the polyethylene 6 mm posterior of the midline, but as the slope increased to 8°, the femur shifted an extra 5 mm, to 11 mm posterior of the tibial midline. Similar shifts were observed for the medial condyle, ranging from 7 mm posterior to 13 mm posterior, respectively. Increasing posterior slope decreased the posterior cruciate ligament tension and femorotibial contact force. CONCLUSION: The results of this study revealed that, although increasing the tibial slope shifted the femur posteriorly at full extension and maximum flexion, it reduced the amount of femoral rollback. Despite the lack of rollback, a more posterior location of condyles suggests lower chances of bearing impingement of the posterior femur and may explain why increasing slope may lead to higher knee flexion.

Anatomic vs Dome Patella: Is There a Difference Between Fixed- vs Mobile-Bearing Posterior-Stabilized Total Knee Arthroplasties?

BACKGROUND: It has been hypothesized that the patella, working in conjunction with both medial and lateral femoral condyles, can influence kinematic parameters such as posterior femoral rollback and axial rotation. The objective of this study is to determine the in vivo kinematics of subjects implanted with a fixed-bearing (FB) or mobile-bearing (MB) posterior-stabilized (PS) total knee arthroplasty (TKA), with a specific focus on evaluating the impact that Anatomic and Medialized Dome patellar components have on tibiofemoral kinematic patterns. METHODS: Tibiofemoral kinematics were assessed for 40 subjects; 20 with an anatomic patella and 20 with a dome patella. Within these groups, 10 subjects received an FB PS TKA and 10 subjects received an MB PS TKA. All subjects were analyzed using fluoroscopy while performing a deep knee bend activity. Kinematics were collected during specific intervals to determine similarities and differences in regard to patella and bearing type. RESULTS: The greatest variation in kinematics was detected between the 2 Anatomic patellar groups. Specifically, the MB-Anatomic subjects experienced greater translation of the lateral condyle, the highest magnitude of axial rotation, and the highest range of motion compared to the FB-Anatomic subjects. Subjects with a Dome Patella displayed much variability among the average kinematics, with all parameters between FB and MB cohorts being similar. CONCLUSION: The findings in this study suggest that subjects with an Anatomic patellar component could have more normal kinematic patterns with an MB PS TKA as opposed to an FB PS TKA, while subjects with a Dome patella could achieve similar kinematics regardless of TKA type.

Effects of the Medial Plateau Bearing Insert Conformity on Mid-Flexion Paradoxical Motion in a Posterior-Stabilized Total Knee Arthroplasty Design.

BACKGROUND: One of the most common kinematic abnormalities reported for posterior-stabilized (PS) total knee arthroplasty (TKA) design is paradoxical anterior sliding during early and mid-flexion. PS TKAs have been designed such that the cam-post mechanism does not engage until later in flexion, making these implants vulnerable to anterior sliding during early and mid-flexion. The objective of this study is to investigate the biomechanical effect of increasing bearing conformity on a PS TKA. METHODS: Using a validated computational model of the knee joint, the sagittal conformity of the medial plateau of a PS TKA design was altered. Three scenarios were created and evaluated for mechanics: (1) baseline conformity, (2) increased conformity, and (3) decreased conformity. RESULTS: From full extension to approximately 70° of knee flexion, the medial condyle demonstrated minimal anterior sliding for the increased medial conformity design but revealed anterior sliding of 2 and 4 mm for the baseline and decreased conformity designs, respectively. After cam-post engagement, the medial condyle consistently rolled back for all 3 designs. The lateral condyle experienced consistent rollback throughout the entire flexion range for all 3 designs. However, femorotibial contact force was higher for the increased conformity design, peaking at 3.13 times body weight (×BW) compared to 3.0 × BW contact force for other 2 designs. CONCLUSION: Increasing medial conformity of the bearing insert appears to reduce mid-flexion sliding for PS TKA designs, although this comes at the expense of increased femorotibial forces. This could be due to kinematic conflicts that may be introduced with highly constraining designs.

In Vivo Knee Kinematics: How Important Are the Roles of Femoral Geometry and the Cruciate Ligaments?

BACKGROUND: While posterior cruciate-retaining (PCR) implants are a more common total knee arthroplasty (TKA) design, newer bicruciate-retaining (BCR) TKAs are now being considered as an option for many patients, especially those that are younger. While PCR TKAs remove the ACL, the BCR TKA designs keep both cruciate ligaments intact, as it is believed that the resection of the ACL greatly affects the overall kinematic patterns of TKA designs. The objectives of this study are to assess the in vivo kinematics for subjects implanted with either a PCR or BCR TKA and to compare the in vivo kinematic patterns to the normal knee during flexion. These objectives were achieved with an emphasis on understanding the roles of the cruciate ligaments, as well as the role of changes in femoral geometry of nonimplanted anatomical femurs vs implanted subjects having a metal femoral component. METHODS: Tibiofemoral kinematics of 50 subjects having a PCR (40 subjects) or BCR (10 subjects) TKA were analyzed using fluoroscopy while performing a deep knee bend activity. The kinematics were compared to previously published normal knee data (10 subjects). Kinematics were determined during specific intervals of flexion where the ACL or PCL was most dominant. RESULTS: In early flexion, subjects having a BCR TKA experienced more normal-like kinematic patterns, possibly attributed to the ACL. In mid-flexion, both TKA groups exhibited variable kinematic patterns, which could be due to the transitional cruciate ligament function period. In deeper flexion, both TKA functioned more similar to the normal knee, leading to the assumption that the PCL was properly balanced and functioning in the TKA groups. Interestingly, during late flexion (after 90°), the kinematic patterns for all three groups appeared to be statistically similar. CONCLUSION: Subjects having a PCR TKA experienced greater weight-bearing flexion than the BCR TKA group. Subjects having a BCR TKA exhibited a more normal-like kinematic pattern in early and late flexion. The normal knee subjects achieved greater lateral condyle rollback and axial rotation compared to the TKA groups.

Can an OA Knee Brace Effectively Offload the Medial Condyle? An In Vivo Fluoroscopic Study.

BACKGROUND: Previous studies evaluating the effectiveness of OA offloading knee braces focused on qualitative results. The objective of this study was to analyze the effectiveness of an off-loading knee brace with respect to in vivo three-dimensional knee kinematics to quantitatively measure the changes in medial joint space and relative bone alignment when wearing the brace. METHODS: Twenty subjects diagnosed with medial compartmental joint space narrowing and varus deformity due to OA were recruited. During fluoroscopic surveillance, subjects performed normal gait on a treadmill with and without the brace. Images were sequenced at heel-strike and mid-stance during the weight-bearing portion of gait. 3D-to-2D image registration was performed on each subject using 3D bone models derived from CT segmentation and 3D ultrasound scans. RESULTS: Medial joint space was to increase when the brace was applied in all subjects (1.6 ± 0.7 mm at heel-strike, 1.6 ± 0.8 mm at mid-stance) and was statistically significant (P < .001). It was also found that sixteen of the twenty subjects experienced a medial joint space increase of more than 1.0 mm during heel-strike while thirteen of twenty experienced this change at mid-stance. While wearing the brace, over half of the subjects experienced a valgus correction to their alignment. CONCLUSIONS: All subjects in this study experienced a positive change in the medial joint space when wearing the offloading knee brace. In addition, many subjects also saw joint space values representative of previously documented, nonosteoarthritic subjects and valgus changes in bone alignment more akin to the normal knee.

A Validated Forward Solution Dynamics Mathematical Model of the Knee Joint: Can It Be an Effective Alternative for Implant Evaluation?

BACKGROUND: Mathematical modeling is among the most common computational tools for assessing total knee arthroplasty (TKA) mechanics of different implant designs and surgical alignments. The main objective of this study is to describe and validate a forward solution mathematical of the knee joint to investigate the effects of TKA design and surgical conditions on TKA outcomes. METHODS: A 12-degree of freedom mathematical model of the human knee was developed. This model includes the whole lower extremity of the human body and comprises major muscles and ligaments at the knee joint. The muscle forces are computed using a proportional-integral-derivative controller, and the joint forces are calculated using a contact detection algorithm. The model was validated using telemetric implants and fluoroscopy, and the sensitivity analyses were performed to determine how sensitive the model is to both implant design, which was analyzed by varying medial conformity of the polyethylene, and surgical alignment, which was analyzed by varying the posterior tibial tilt. RESULTS: The model predicted the tibiofemoral joint forces with an average accuracy of 0.14× body weight (BW), 0.13× BW, and 0.17× BW root-mean-square errors for lateral, medial, and total tibiofemoral contact forces. With fluoroscopy, the kinematics were validated with an average accuracy of 0.44 mm, 0.62 mm, and 0.77 root-mean-square errors for lateral anteroposterior position, medial anteroposterior position, and axial rotation, respectively. Increasing medial conformity resulted in reducing the paradoxical anterior sliding midflexion. Furthermore, increasing posterior tibial slopes shifted the femoral contact point more posterior on the bearing and reduced the tension in the posterior cruciate ligament. CONCLUSION: A forward solution dynamics model of the knee joint was developed and validated using telemetry devices and fluoroscopy data. The results of this study suggest that a validated mathematical model can be used to predict the effects of component design and surgical conditions on TKA outcomes.

In Vivo Knee Kinematics for a Cruciate Sacrificing Total Knee Arthroplasty Having Both a Symmetrical Femoral and Tibial Component.

BACKGROUND: Early total knee arthroplasty (TKA) designs were symmetrical, but lead to complications due to over-constraint leading to loosening and poor flexion. Next-generation TKAs have been designed to include asymmetry, pertaining to the trochlear groove, femoral condylar shapes, and/or the tibial component. More recently, an advanced posterior cruciate sacrificing (PCS) TKA was designed to include both a symmetrical femoral component with a patented V-shaped trochlear groove and a symmetrical tibial component with an ultracongruent insert, in an attempt to reduce inventory costs. Because previous PCS TKA designs produced variable results, the objective of this study is to determine and evaluate the in vivo kinematics for subjects implanted with this symmetrical TKA. METHODS: Twenty-one subjects, implanted with symmetrical PCS fixed-bearing TKA, were asked to perform a weight-bearing deep knee bend (DKB) while under fluoroscopic surveillance. A 3-dimensional to 2-dimensional registration technique was used to determine each subject's anteroposterior translation of lateral and medial femoral condyles as well as tibiofemoral axial rotation and their weight-bearing knee flexion. RESULTS: During the DKB, the average active maximum weight-bearing flexion was 111.7° ± 13.3°. On average, from full extension to maximum knee flexion, subjects experienced -2.5 ± 2.0 mm of posterior femoral rollback of the lateral condyle and 2.5 ± 2.2 mm of medial condyle motion in the anterior direction. This medial condyle motion was consistent for the majority of the subjects, with the lateral condyle exhibiting rollback from 0° to 60° of flexion and then experienced an average anterior motion of 0.3 mm from 60° to 90° of knee flexion. On average, the subjects in this study experienced 6.6°± 3.3° of axial rotation, with most of the rotation occurring in early flexion, averaging 4.9°. CONCLUSION: Although subjects in this study were implanted with a symmetrical PCS TKA, they did experience femoral rollback of the lateral condyle and a normal-like pattern of axial rotation, although less in magnitude than the normal knee. The normal axial rotation pattern occurred because the lateral condyle rolled in the posterior direction, while the medial condyle moved in the anterior direction. Interestingly, the magnitude of posterior femoral rollback and axial rotation for subjects in this study was similar in magnitude reported in previous studies pertaining to asymmetrical TKA designs. It is proposed that more patients be analyzed having this TKA implanted by other surgeons.

Kinematic Performance of Gradually Variable Radius Posterior-Stabilized Primary TKA During Various Activities: An In Vivo Study Using Fluoroscopy.

BACKGROUND: Posterior-stabilized total knee arthroplasty (TKA) with gradually variable radii (G-curve) femoral condylar geometry is now available. It is believed that a G-curve design would lead to more mid-flexion stability leading to reduced incidence of paradoxical anterior slide. The objective of this study was to assess the in vivo kinematics for subjects implanted with this type of TKA under various conditions of daily living. METHODS: Tibiofemoral kinematics of 35 patients having posterior-stabilized TKA with G-curve design were analyzed using fluoroscopy while performing three activities: weight-bearing deep knee bend, gait, and walking down a ramp. The subjects were assessed for range of motion, condylar translation, axial rotation, cam-spine engagement, and condylar lift-off. RESULTS: The average weight-bearing flexion during deep knee bend was 111.4°. On average, the subjects exhibited 5.4 mm of posterior rollback of the lateral condyle and 2.0 mm of the medial condyle from full extension to maximum knee flexion. The femur consistently rotated externally with flexion, and the average axial rotation was 5.2°. Overall movement of the condyles during gait and ramp-down activity was small. No incidence of condylar lift-off was observed. CONCLUSION: Subjects in this study experienced consistent magnitudes of posterior femoral rollback and external rotation of the femur with weight-bearing flexion. The variation is similar to that previously reported for normal knee where the lateral condyle moves consistently posterior compared to the medial condyle. Subjects experienced low overall mid-flexion paradoxical anterior sliding and no incidence of condylar lift-off leading to mid-flexion stability.

In Vivo Determination and Comparison of Total Hip Arthroplasty Kinematics for Normal, Preoperative Degenerative, and Postoperative Implanted Hips.

BACKGROUND: The study objective is to analyze subjects having a normal hip and compare in vivo kinematics to subjects before and after receiving a total hip arthroplasty. METHODS: Twenty subjects, 10 with a normal hip and 10 with a preoperative, degenerative hip were analyzed performing normal walking on level ground while under fluoroscopic surveillance. Seven preoperative subjects returned after receiving a total hip arthroplasty using the anterior surgical approach by a single surgeon. Using 3-dimensional to 2-dimensional registration techniques, joint models were overlayed on fluoroscopic images to obtain transformation matrices in the image space. From these images, displacements of the femoral head and acetabulum centers were computed, as well as changes in contact patches between the 2 surfaces throughout the gait cycle. RESULTS: Implanted hips experienced the least amount of separation, compression, and overall sliding throughout the entire gait cycle, but they did show signs of edge loading contact patterns. Conversely, the degenerative hips experienced the most compression, sliding, and separation, with the maximum amount of sliding being 6.9 mm. The normal group ranged in the middle, with the maximum amount of sliding being 1.75 mm. CONCLUSION: Current analysis revealed trends that degenerative hips experience more abnormal hip kinematics that leads to higher articulating surface forces and stresses within the acetabulum. None of the implanted hips experienced hip separation.

Total Knee Arthroplasty Kinematics.

Knee kinematics is an analysis of motion pattern that is utilized to assess a comparative, biomechanical performance of healthy nonimplanted knees, injured nonimplanted knees, and various prosthetic knee designs. Unfortunately, a consensus between implanted knee kinematics and outcomes has not been reached. One might hypothesize that the kinematic variances between the nonimplanted and implanted knee might play a role in patient dissatisfaction following TKA. There is a wide range of TKA designs available today. With such variety, it is important for surgeons and engineers to understand the various geometries and kinematic profiles of available prostheses. The purpose of this review is to provide readers with the pertinent information related to TKA kinematics.

In Vivo Kinematic Comparison of a Bicruciate Stabilized Total Knee Arthroplasty and the Normal Knee Using Fluoroscopy.

BACKGROUND: The bicruciate stabilized (BCS) total knee arthroplasty (TKA) features asymmetrical bearing geometry and dual substitution for the anterior cruciate ligament and posterior cruciate ligament (PCL). Previous TKA designs have not fully replicated normal knee motion, and they are characterized by lower magnitudes of overall rollback and axial rotation than the normal knee. METHODS: In vivo kinematics were derived for 10 normal knees and 40-second generation BCS TKAs all implanted by a single surgeon. Mobile fluoroscopy and three-dimensional-to-two-dimensional registration was used to analyze anterior-posterior motion of the femoral condyles and femorotibial axial rotation during weight-bearing flexion. Statistical analysis was conducted at the 95% confidence level. RESULTS: From 0° to 30° of knee flexion, the BCS subjects exhibited similar patterns of femoral rollback and axial rotation compared to normal knee subjects. From 30° to 60° of knee flexion, BCS subjects experienced negligible anterior-posterior motions and axial rotation while normal knees continued to rollback and externally rotate. Between 60° and 90° the BCS resumed posterior motion and, after 90°, axial rotation increased in a normal-like fashion. CONCLUSION: Similarities in early flexion kinematics suggest that the anterior cam-post is supporting normal-like anterior-posterior motion in the BCS subjects. Likewise, lateral femoral rollback and external rotation of the femur in later flexion provides evidence for appropriate substitution of the PCL via the posterior cam-post. Being discrete in nature, the dual cam-post mechanism does not lend itself to adequate substitution of the cruciate ligaments in mid-flexion during which anterior cruciate ligament tension is decreasing and PCL tension is increasing in the normal knee.

Customized versus Patient-Sized Cruciate-Retaining Total Knee Arthroplasty: An In Vivo Kinematics Study Using Mobile Fluoroscopy.

BACKGROUND: Historically, knee arthroplasties have been designed using average patient anatomy. Recent advances in imaging and manufacturing have facilitated the development of customized prostheses designed to fit the unique shape of individual patients. The purpose of this study is to determine if improving implant design through customized total knee arthroplasty (TKA) improves kinematic function. METHODS: Using state-of-the-art mobile fluoroscopy, tibiofemoral kinematics were analyzed for 24 subjects with a customized individually made (CIM), cruciate-retaining TKA, and 14 subjects having an asymmetric condylar cruciate-retaining TKA. Subjects performed a weight-bearing deep knee bend and a rise from a seated position. Each patient was evaluated for weight-bearing range of motion, femorotibial translation, femorotibial axial rotation, and condylar liftoff occurrence. RESULTS: Subjects having a CIM TKA experienced greater weight-bearing knee flexion compared with the traditional posterior cruciate-retaining (PCR) TKA design. During flexion, the CIM TKA subjects consistently exhibited more posterior femoral rollback than the traditional PCR TKA subjects. The CIM TKA was found to have statistically greater axial rotation compared with the traditional PCR TKA (P = .05). Of note, only the CIM TKA patients experienced femoral internal rotation at full extension, as exhibited in a normal knee. Compared with the traditional PCR TKA, the CIM TKAs demonstrated minimal occurrences of paradoxical sliding and reverse rotation during flexion and extension. The CIM TKA subjects showed minimal liftoff and hence better stability in earlyflexion to midflexion compared with the traditional PCR subjects. CONCLUSION: The CIM TKA demonstrated kinematics more similar to a normal knee. Therefore, using customized implant technology through CIM TKA designs affords benefits including more normal motion compared with a traditional PCR TKA.

Single Versus Multiple-Radii Cruciate-Retaining Total Knee Arthroplasty: An In Vivo Mobile Fluoroscopy Study.

BACKGROUND: Previous fluoroscopic studies, using static C-arm systems, have shown nonnormal kinematic patterns in cruciate-retaining (CR) total knee arthroplasty (TKA). This study compares in vivo the kinematic differences in subjects implanted with single sagittal radius (SR) vs multiradii (MR) CR TKA for various activities using a novel mobile fluoroscopic system. METHODS: Using mobile fluoroscopy and 3D to 2D registration, tibiofemoral kinematics were analyzed for 25 subjects with an SR, symmetrical condylar CR TKA and 25 subjects with an MR, asymmetric condylar CR TKA for three dynamic weight-bearing activities: (1) deep knee bend (DKB), (2) walking up a ramp, and (3) walking down a ramp. RESULTS: During DKB, from full extension to maximum knee flexion, the SR (-0.43 ± 3.43 mm) and MR (-1.00 ± 3.23 mm) groups experienced statistically similar anterior/posterior (AP) motion in the lateral condyle. The SR (3.51 ± 2.68 mm) group had significant anterior movement compared to the MR (-0.42 ± 2.20 mm) group in the medial condyle. This resulted in a significantly larger amount of normal axial rotation experienced by the SR (5.20 ± 3.93°) group compared to the MR (0.75 ± 5.12°) group. During ramp activities, the SR TKA consistently exhibited a significantly more posterior position of both condyles compared to the MR TKA. CONCLUSION: Although the SR TKA exhibited larger amounts of axial rotation compared to the MR TKA in DKB, neither design exhibited weight-bearing kinematics as previously reported for the normal knee. Additional research on the normal knee for ramp activities is required to understand the importance of condylar position during these activities.

Analysis of the Flexion Gap on In Vivo Knee Kinematics Using Fluoroscopy.

There is a paucity of information on the relationships between postoperative knee laxity and in vivo knee kinematics. The correlations were analyzed in 22 knees with axial radiographs and fluoroscopy based 3D model fitting approach after a tri-condylar total knee arthroplasty. During deep knee bend activities, the medial flexion gap had significant correlations with the medial contact point (r=0.529, P=0.011) and axial rotation at full extension. During kneeling activities, a greater medial flexion gap caused larger anterior translation at complete contact (r=0.568, P=0.011). Meanwhile, the lateral flexion gap had less effect. In conclusion, laxity of the medial collateral ligament should be avoided because the magnitude of medial flexion stability was crucial for postoperative knee kinematics.

Kinematic difference between various geometric centers and contact points for tri-condylar bi-surface knee system.

The purpose of the study was to analyze the motion of contact points (CPs), lowest points (LPs), and component facet centers of tri-condylar implants. In vivo knee kinematics was assessed for 43 knees implanted with a multi-radii femoral component during deep knee bend activity, using a model fitting approach. Both LPs had the similar positions to the corresponding geometric centers of the femoral component, and the LP and geometric center angles represented the same component rotation angle defined by Grood and Suntay. Antero-posterior translation of both CPs was significantly overestimated, compared to LPs, and the CP angle showed significant differences from other rotation angles. In conclusion LPs seemed better to evaluate kinematics than CPs because polyethylene congruity had considerable effects on CP analysis.

Abnormal axial rotations in TKA contribute to reduced weightbearing flexion.

BACKGROUND: Previous in vivo fluoroscopy studies have documented that axial rotation for patients having a TKA was significantly less than those having a normal knee. In fact, many subjects having a TKA experience a reverse axial rotation pattern where the femur internally rotates with increasing flexion. However, no previous studies have been conducted to determine if this reverse axial rotation pattern affects TKA performance. QUESTIONS/PURPOSES: The purposes of this study were: (1) Do normal and reverse axial rotation patterns of a TKA affect the maximum flexion angle postoperatively? (2) Does the axial rotation angle of the knee at maximum flexion during weightbearing impact the magnitude of the maximum flexion achieved in weightbearing? METHODS: One hundred twenty patients having TKA, previously analyzed under in vivo conditions using fluoroscopy and a three-dimensional model-fitting software package, were further evaluated to determine if reverse axial rotation patterns limit weightbearing TKA flexion. In this retrospective cohort, we identified 58 patients who had a normal axial rotation pattern (greater than 15° normal rotation). Sixty-two patients experienced greater than 3° of reverse axial rotation, defined as internal rotation of the femur relative to the tibia. RESULTS: Patients having a normal axial rotation achieved greater weightbearing knee flexion than those with reverse axial rotation (115° versus 109°, p = 0.02). Additionally, patients with greater than 3° of normal axial rotation at maximum flexion had more flexion than those with less than 3° of normal axial rotation at ending flexion (115° versus 107°, p < 0.001). CONCLUSIONS: These findings show reverse axial rotation and a smaller magnitude of normal axial rotation reduce weightbearing knee flexion. This is likely the result of increased posterior movement of the lateral condyle and is an important consideration in future implant designs.

In vivo determination of cam-post engagement in fixed and mobile-bearing TKA.

BACKGROUND: Kinematics vary, sometimes in important ways, among the different types of total knee arthroplasty (TKA) designs, yet differences between the in vivo mechanisms of cam-post engagement in rotating-platform posterior-stabilized (PS) TKA, bicruciate-stabilized TKA, and fixed-bearing PS TKA designs remain largely uncharacterized. QUESTIONS/PURPOSES: The objective of this study was to determine the cam-post mechanism interaction for subjects implanted with three different TKA designs. METHODS: In vivo, analysis was conducted for patients implanted with nine rotating-platform PS TKAs, five knees with a fixed-bearing PS TKA, and 10 knees with a bicruciate-stabilized TKA while performing a deep knee bend. Three-dimensional kinematics of the implant components were determined by analysis of fluoroscopic images during flexion. The distances between the interacting surfaces were measured throughout flexion and instances and locations of contact were identified. RESULTS: Seven of the 10 bicruciate-stabilized knees analyzed had the femoral component engaged with the anterior aspect of the tibial post at full extension. Posterior cam-post engagement occurred at 34° for the bicruciate-stabilized (range, 17°-68°), 93° for the fixed-bearing PS (range, 88°-100°), and at 97° (range, 90°-104°) for rotating-platform PS TKA. In bicruciate-stabilized and fixed-bearing PS knees, the contact initially occurred on the medial aspect of the posterior surface of the tibial post and then moved centrally and superiorly with increasing flexion. For rotating-platform PS TKA, it was located centrally on the posterior surface of the post at all times. CONCLUSIONS: This study suggests that mobility of the polyethylene might play an important role in ensuring central cam-post interaction in PS TKA. The polyethylene insert rotates axially in accordance with the rotating femur, maintaining central cam-post contact. This phenomenon was not observed in the fixed-bearing PS TKAs analyzed in this study. CLINICAL RELEVANCE: We speculate that this centralized symmetrical contact between the cam and posterior surface of the post could be beneficial clinically in terms of reducing wear of the posterior surface and particularly at the medial extremes of it.

Confirmation of long-term in vivo bearing mobility in eight rotating-platform TKAs.

BACKGROUND: Posterior-stabilized rotating-platform prostheses for TKAs were designed to improve contact mechanics at the femoral-polyethylene (PE) interface. Short-term followup studies have shown that the PE bearings rotate with respect to the tibia but might not necessarily track with the femur. It is important to know how kinematics in these designs change owing to long-term in vivo use. QUESTIONS/PURPOSES: We asked whether there is a significant change in the in vivo kinematic performance of a posterior-stabilized rotating-platform prosthesis at as much as 10 years postoperative. We specifically examined (1) relative femoral component-PE bearing and relative PE bearing-tibial tray motion; (2) relative AP motion of the femoral condyles with respect to the tibial tray; and (3) relative femorotibial condylar translations. METHODS: In vivo three-dimensional kinematics were evaluated for eight patients at 3 months, 15 months, 5 years, and 10 years after TKA with primary implantation of a posterior-stabilized rotating-platform prosthesis. Each patient performed deep knee bend activity, and three-dimensional kinematics were reconstructed from multiple fluoroscopic images using a three-dimensional to two-dimensional registration technique. Once complete, relative component axial rotation patterns, medial and lateral condyle motions throughout flexion, and the presence of femoral condylar lift-off were analyzed. RESULTS: Overall, tibial bearing rotation was maintained at 10 years postoperatively. There was no statistical difference between postoperative periods for any kinematic parameter except for femoral component-PE bearing axial rotation, which was reduced at the 10-year evaluation versus other assessment periods (p = 0.0006). The lack of statistical difference between postoperative evaluation periods indicates sustained overall implant kinematic performance. CONCLUSIONS: Our study showed that PE bearing-tibial tray mobility was maintained and that femoral component-PE bearing rotation was reduced at the 10-year followup. This suggests that the overall kinematic performance of this mobile-bearing implant is not negatively affected 10 years postoperatively. LEVEL OF EVIDENCE: Level III, retrospective study. See the Instructions for Authors for a complete description of levels of evidence.