RESUMEN
Cervical near-hanging injuries are most frequent in the young adult population. However, the literature gives little guidance regarding diagnostic evaluation of these patients, although it is well known that their initial clinical presentation has limited prognostic value. This case report presents a patient who actually survived a suicidal near-hanging attempt and was later able to walk and talk to his physician. He died the next day due to carotid dissection and cerebral ischemia. In this case report we emphasize the importance of thorough radiological investigation in the accurate assessment of these patients. Early imaging should be performed routinely after near-hanging injury, in order to establish the correct diagnosis and allow appropriate treatment to be started.
Asunto(s)
Cuello , Suicidio , Disección de la Arteria Carótida Interna/etiología , Resultado Fatal , Escala de Coma de Glasgow , Humanos , Masculino , Persona de Mediana Edad , PronósticoRESUMEN
OBJECTIVES: Endovascular techniques are an integral part of modern-day vascular surgery practice and training. Nevertheless, validated in vitro assessment tools for these skills are scarce. This study describes the development and pilot testing of the Simulator for Testing and Rating Endovascular Skills (STRESS machine). DESIGN: The design was kept straightforward and compact, without the need for contrast or fluoroscopy. A specific technical skill score was designed analogous to the Imperial College Evaluation of Procedural Skill (ICEPS), an assessment score for open surgical skill. This score was combined with an already validated global rating assessment to form the total score (TS). METHODS: A pilot study was carried out on 18 candidates of varying levels of expertise: novice, intermediate and expert, who were assessed by two independent observers to test inter-observer reliability. RESULTS: Inter-observer reliability was excellent, Cronbach's alpha coefficient of the TS was 0.94 (95% confidence interval: 0.84-0.97). A one-way analysis of variance (ANOVA) showed a significant difference between the novice and expert groups (p<0.001), between the novice and intermediate groups (p<0.01) and between the intermediate and expert groups (p<0.05). CONCLUSION: The STRESS machine, in combination with the specific technical skill score and global rating assessment, provides a reliable method of discriminating between the novice, intermediate and expert candidates with excellent inter-observer variability.
Asunto(s)
Cateterismo , Competencia Clínica , Simulación por Computador , Obstrucción de la Arteria Renal/terapia , Humanos , Proyectos Piloto , Reproducibilidad de los Resultados , Factores de TiempoAsunto(s)
Aneurisma de la Aorta/cirugía , Aortografía/métodos , Implantación de Prótesis Vascular , Procedimientos Endovasculares , Complicaciones Posoperatorias/diagnóstico , Tomografía Computarizada por Rayos X , Ultrasonografía Doppler Dúplex , Aneurisma de la Aorta/diagnóstico , Aneurisma de la Aorta/economía , Aortografía/efectos adversos , Aortografía/economía , Implantación de Prótesis Vascular/efectos adversos , Implantación de Prótesis Vascular/economía , Ahorro de Costo , Procedimientos Endovasculares/efectos adversos , Procedimientos Endovasculares/economía , Costos de Hospital , Humanos , Estimación de Kaplan-Meier , Cuidados Posoperatorios , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/economía , Complicaciones Posoperatorias/terapia , Valor Predictivo de las Pruebas , Dosis de Radiación , Factores de Tiempo , Tomografía Computarizada por Rayos X/efectos adversos , Tomografía Computarizada por Rayos X/economía , Resultado del Tratamiento , Ultrasonografía Doppler Dúplex/economía , Procedimientos Innecesarios/economíaRESUMEN
Isolated hepatic perfusion (IHP) involves a method of complete vascular isolation of the liver to allow treatment of liver tumours with toxic systemic doses. The recent clinical studies mainly employed IHP with melphalan with or without tumour necrosis factor-alpha (TNF-alpha) and mild hyperthermia. The results of these studies show that high response rates and high survival rates can be achieved by IHP. In this article, the current status, recent developments and future perspectives of IHP are discussed.
Asunto(s)
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Quimioterapia del Cáncer por Perfusión Regional/métodos , Neoplasias Colorrectales , Neoplasias Hepáticas/tratamiento farmacológico , Neoplasias Hepáticas/secundario , Humanos , Hipertermia Inducida/métodos , Melfalán/administración & dosificación , Melfalán/farmacocinética , Resultado del Tratamiento , Factor de Necrosis Tumoral alfa/administración & dosificación , Factor de Necrosis Tumoral alfa/farmacocinéticaRESUMEN
We retrospectively reviewed our experience with subintimal angioplasty for chronic limb ischemia. Hospital records and films of all subintimal angioplasty procedures performed between October 2002 and December 2004 were reviewed and analyzed for demographic data, clinical data, and comorbid condition status. Thirty-nine subintimal angioplasties were performed in 37 patients (65% male, 35% female), with a median age of 73 years. Median follow-up was 9 months. The 30-day mortality rate was 8%. All-cause mortality was 33% after 24 months. In 23 cases (59%), a subintimal angioplasty of the superficial femoral artery (SFA) alone was performed. Both the SFA and popliteal/crural vessels were used in nine limbs (23%), the popliteal artery alone in three limbs (8%), and the crural arteries alone in four limbs (10%). Initial technical and clinical success rates were 67% and 49%, respectively. The complication rate was 28%. Twenty-four additional surgical interventions were performed after the initial angioplasty procedure, of which 12 were major amputations. Amputation-free survival (limb-salvage rate) was 69% at 12 months [95% confidence interval (CI) 52-85%], and overall survival was 69% (95% CI 52-85%) at 12 months. In patients with critical limb ischemia, subintimal angioplasty is feasible and in most cases technically successful. In these high-risk patients, often with combined cardiac, pulmonary, and diabetic risk and considered unfit for bypass surgery, subintimal angioplasty offers a safe and effective alternative.