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2.
Clin J Sport Med ; 29(6): 482-485, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-31688179

RESUMEN

INTRODUCTION: Exercise-related injuries (ERIs) are a common cause of nonfatal emergency department and hospital visits. CrossFit is a high-intensity workout regimen whose popularity has grown rapidly. However, ERIs due to CrossFit remained under investigated. METHODS: All patients who presented to the main hospital at a major academic center complaining of an injury sustained performing CrossFit between June 2010 and June 2016 were identified. Injuries were classified by anatomical location (eg, knee, spine). For patients with spinal injuries, data were collected including age, sex, body mass index (BMI), CrossFit experience level, symptom duration, type of symptoms, type of clinic presentation, cause of injury, objective neurological examination findings, imaging type, number of clinic visits, and treatments prescribed. RESULTS: Four hundred ninety-eight patients with 523 CrossFit-related injuries were identified. Spine injuries were the most common injuries identified, accounting for 20.9%. Among spine injuries, the most common location of injury was the lumbar spine (83.1%). Average symptom duration was 6.4 months ± 15.1, and radicular complaints were the most common symptom (53%). A total of 30 (32%) patients had positive findings on neurologic examination. Six patients (6.7%) required surgical intervention for treatment after failing an average of 9.66 months of conservative treatment. There was no difference in age, sex, BMI, or duration of symptoms of patients requiring surgery with those who did not. CONCLUSIONS: CrossFit is a popular, high-intensity style workout with the potential to injure its participants. Spine injuries were the most common type of injury observed and frequently required surgical intervention.


Asunto(s)
Acondicionamiento Físico Humano/efectos adversos , Acondicionamiento Físico Humano/métodos , Traumatismos Vertebrales/epidemiología , Adulto , Femenino , Humanos , Vértebras Lumbares/lesiones , Masculino , Persona de Mediana Edad , Modalidades de Fisioterapia , Factores de Riesgo , Lesiones del Hombro/epidemiología , Lesiones del Hombro/etiología , Lesiones del Hombro/terapia , Traumatismos Vertebrales/etiología , Traumatismos Vertebrales/cirugía , Traumatismos Vertebrales/terapia , Adulto Joven
3.
Anesth Analg ; 121(4): 981-987, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-25794113

RESUMEN

BACKGROUND: Neuraxial analgesic techniques are the most effective form of labor analgesia. Small studies (9-21 patients), conducted 10 to 20 years ago, demonstrated successful neuraxial labor analgesia in only 50% to 66% of patients with surgical correction for scoliosis. Newer surgical techniques for scoliosis correction make the epidural space more accessible, but postsurgical changes may still alter the efficacy of neuraxial labor analgesia. The purpose of this prospective case-matched study was to compare hourly bupivacaine consumption and time to placement of neuraxial technique in laboring women with spinal instrumentation compared with women without previous back surgery. METHODS: All women with previous spinal instrumentation surgery for scoliosis correction who requested neuraxial labor analgesia at Prentice Women's Hospital during the study period were approached. Control subjects were matched for anesthesiologist level of experience. The primary outcomes were bupivacaine consumption per hour of labor analgesia and time to placement of the neuraxial technique. Secondary outcomes included supplemental analgesia requirements and neuraxial analgesia failures and complications. RESULTS: Data from 41 women with surgical correction for scoliosis and 41 control subjects requesting neuraxial labor analgesia were analyzed. Obstetric and demographic characteristics of study participants were not different between groups. Median (interquartile range) hourly bupivacaine consumption was 15.2 mg/h (12.5-18.7) in the spinal instrumentation group and 14.2 mg/h (11.8-16.0) in the control group; the difference in medians was 1 mg/h (95% confidence interval [CI], -1.3 to 3.0; P = 0.38). The total bupivacaine consumption, number of manual reboluses, and number of subjects requiring greater bupivacaine concentrations did not differ between groups. Neuraxial analgesia failure occurred in 5 (12%) of women in the spinal instrumentation group but in none of the control patients (difference [95% CI], 12% [-0.3% to 25%]; P = 0.06). The mean time required to complete the neuraxial technique was 41% (95% CI, 7%-108%; P = 0.01) longer in the spinal instrumentation group than in the control group. The spinal instrumentation group also required a greater number of needle redirections, attempted interspaces, and need to switch to a more experienced provider than matched controls. CONCLUSIONS: The findings of this investigation suggest that previous surgery for scoliosis repair does not affect neuraxial labor analgesia consumption, but performance of the neuraxial technique is more difficult. Our findings suggest that neuraxial labor analgesia should be offered to parturients with previous surgery for scoliosis repair although informed consent should include a discussion of the possibility of technical difficulties and surgical anesthesia failure.


Asunto(s)
Analgesia Epidural/métodos , Analgesia Obstétrica/métodos , Catéteres de Permanencia , Escoliosis/cirugía , Adulto , Femenino , Humanos , Manejo del Dolor/métodos , Embarazo , Estudios Prospectivos , Escoliosis/complicaciones , Factores de Tiempo
4.
Neurosurg Focus ; 39(2): E11, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-26235009

RESUMEN

OBJECT Patients with symptomatic intradural-extramedullary (ID-EM) tumors may be successfully treated with resection of the lesion and decompression of associated neural structures. Studies of patients undergoing open resection of these tumors have reported high rates of gross-total resection (GTR) with minimal long-term neurological deficit. Case reports and small case series have suggested that these patients may be successfully treated with minimally invasive surgery (MIS). These studies have been limited by small patient populations. Moreover, there are no studies directly comparing perioperative outcomes between patients treated with open resection and MIS. The objective of this study was to compare perioperative outcomes in patients with ID-EM tumors treated using open resection or MIS. METHODS A retrospective review was performed using data collected from 45 consecutive patients treated by open resection or MIS for ID-EM spine tumors. These patients were treated over a 9-year period between April 2003 and October 2012 at Northwestern University and the University of Chicago. Statistical analysis was performed to compare perioperative outcomes between the two groups. RESULTS Of the 45 patients in the study, 27 were treated with the MIS approach and 18 were treated with the open approach. Operative time was similar between the two groups: 256.3 minutes in the MIS group versus 241.1 minutes in the open group (p = 0.55). Estimated blood loss was significantly lower in the MIS group (133.7 ml) compared with the open group (558.8 ml) (p < 0.01). A GTR was achieved in 94.4% of the open cases and 92.6% of the MIS cases (p = 0.81). The mean hospital stay was significantly shorter in the MIS group (3.9 days) compared with the open group (6.1 days) (p < 0.01). There was no significant difference between the complication rates (p = 0.32) and reoperation rates (p = 0.33) between the two groups. Multivariate analysis demonstrated an increased rate of complications in cervical spine tumors (OR 15, p = 0.05). CONCLUSIONS Thoracolumbar ID-EM tumors may be safely and effectively treated with either the open approach or an MIS approach, with an equivalent rate of GTR, perioperative complication rate, and operative time. Patients treated with an MIS approach may benefit from a decrease in operative blood loss and shorter hospital stays.


Asunto(s)
Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Procedimientos Neuroquirúrgicos/métodos , Neoplasias de la Médula Espinal/cirugía , Médula Espinal/cirugía , Vértebras Torácicas/cirugía , Adulto , Anciano , Pérdida de Sangre Quirúrgica/prevención & control , Pérdida de Sangre Quirúrgica/estadística & datos numéricos , Femenino , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Médula Espinal/patología , Neoplasias de la Médula Espinal/patología , Vértebras Torácicas/patología , Resultado del Tratamiento
5.
Clin Spine Surg ; 37(2): E97-E105, 2024 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-37941100

RESUMEN

STUDY DESIGN: A retrospective cohort study. OBJECTIVE: To calculate the magnitude of any increased risk of epidural hematoma (EDH) associated with chemoprophylactic anticoagulation (chemoprophylaxis), if any. SUMMARY OF BACKGROUND DATA: Chemoprophylaxis for the prevention of venous thromboembolic events may be associated with an increased risk of EDH after spine surgery. MATERIALS AND METHODS: A total of 6869 consecutive spine surgeries performed at our institution were identified, and clinical and demographic data were collected. We identified cases in which symptomatic EDHs were evacuated within 30 days postoperatively. Patients receiving chemoprophylaxis and controls were matched using K-nearest neighbor propensity score matching to calculate the effect of anticoagulation on the rate of postoperative EDH. RESULTS: After propensity score matching, 1071 patients who received chemoprophylaxis were matched to 1585 controls. Propensity scores were well balanced between populations (Rubin B=20.6, Rubin R=1.05), and an 89.6% reduction in bias was achieved, with a remaining mean bias of 3.2%. The effect of chemoprophylaxis on EDH was insignificant ( P =0.294). Symptomatic EDH was independently associated with having a transfusion [odds ratio (OR)=7.30 (1.15, 46.20), P =0.035], having thoracic-level surgery [OR=41.19 (3.75, 452.4), P =0.002], and increasing body mass index [OR=1.44 (1.04, 1.98), P =0.028] but was not associated with chemoprophylaxis. Five out of 13 patients who developed EDH (38.5%) were receiving some form of anticoagulation, including 1 patient on therapeutic anticoagulation, 1 concurrently on aspirin and chemoprophylaxis, and 2 who were also found to have developed thrombocytopenia postoperatively. The median time on anticoagulation before EDH was 8.1 days. A higher proportion of patients who developed EDH also developed venous thromboembolic events than the general population [38.5% vs. 2.4%, OR=25.34 (9.226, 79.68), P <0.0001], and 1 EDH patient died from pulmonary embolism while off chemoprophylaxis. CONCLUSIONS: Chemoprophylactic anticoagulation did not cause an increase in the rate of spinal EDH in our patient population.


Asunto(s)
Hematoma Espinal Epidural , Tromboembolia Venosa , Trombosis de la Vena , Humanos , Estudios Retrospectivos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/prevención & control , Complicaciones Posoperatorias/epidemiología , Trombosis de la Vena/complicaciones , Trombosis de la Vena/tratamiento farmacológico , Trombosis de la Vena/epidemiología , Tromboembolia Venosa/etiología , Tromboembolia Venosa/prevención & control , Hematoma Espinal Epidural/prevención & control , Anticoagulantes/efectos adversos , Factores de Riesgo
6.
Spine (Phila Pa 1976) ; 48(3): 172-179, 2023 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-36191060

RESUMEN

STUDY DESIGN: Retrospective cohort. OBJECTIVE: To quantify any reduction in venous thromboembolic events (VTEs) caused by chemoprophylaxis among lumbar surgery patients. SUMMARY OF BACKGROUND DATA: Chemoprophylactic anticoagulation (chemoprophylaxis) is used to prevent VTE after lumbar surgery. However, the treatment effect of chemoprophylaxis has not been reported among spine surgery patients, as conventional statistical methods preclude such inferences. MATERIALS AND METHODS: A total of 1243 consecutive lumbar fusions and 1433 noninstrumented lumbar decompressions performed at our institution over a six-year period were identified, and clinical and demographic data were collected, including on VTE events within 30 days postoperatively. Instrumented lumbar fusions and noninstrumented lumbar surgeries were analyzed separately. Patients who were given chemoprophylaxis (treatment) and controls were matched according to known VTE risk factors, including age, body mass index, sex, diabetes, chronic kidney disease, history of VTE, estimated blood loss, length of surgery, transfusion, whether surgery was staged, and whether surgery used an anterior approach. K-nearest neighbor propensity score matching was performed, and the treatment effect of chemoprophylaxis was calculated. RESULTS: Unadjusted, there was no difference in the rate of VTE between treatment and controls in either population. Baseline clinical and demographic characteristics differed significantly between treatment and control groups. In all, 575 lumbar fusion patients and 435 noninstrumented lumbar decompression patients were successfully propensity score matched, yielding balanced models (Rubin B <25, 0.560% reduction in known bias for both populations. The treatment effect of chemoprophylaxis after lumbar fusion in our patient population was a reduction in VTE incidence from 9.4% to 4.2% ( P <0.05), and propensity score adjusted regression confirmed a reduced odds of VTE with chemoprophylaxis (odds ratio=0.37, P =0.035). The treatment effect was not significant for noninstrumented lumbar decompression patients. CONCLUSION: Among patients undergoing instrumented lumbar fusions, chemoprophylactic anticoagulation causes a significant reduction in VTE, but causes no significant reduction among patients undergoing noninstrumented lumbar decompression.


Asunto(s)
Tromboembolia Venosa , Trombosis de la Vena , Humanos , Tromboembolia Venosa/etiología , Tromboembolia Venosa/prevención & control , Tromboembolia Venosa/epidemiología , Estudios Retrospectivos , Complicaciones Posoperatorias/epidemiología , Trombosis de la Vena/etiología , Anticoagulantes/uso terapéutico
7.
Trends Mol Med ; 29(9): 740-752, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37349248

RESUMEN

The global aging population has led to an increase in geriatric diseases, including adult degenerative scoliosis (ADS). ADS is a spinal deformity affecting adults, particularly females. It is characterized by asymmetric intervertebral disc and facet joint degeneration, leading to spinal imbalance that can result in severe pain and neurological deficits, thus significantly reducing the quality of life. Despite improved management, molecular mechanisms driving ADS remain unclear. Current literature primarily comprises epidemiological and clinical studies. Here, we investigate the molecular mechanisms underlying ADS, with a focus on angiogenesis, inflammation, extracellular matrix remodeling, osteoporosis, sarcopenia, and biomechanical stress. We discuss current limitations and challenges in the field and highlight potential translational applications that may arise with a better understanding of these mechanisms.


Asunto(s)
Disco Intervertebral , Escoliosis , Femenino , Humanos , Adulto , Anciano , Escoliosis/genética , Calidad de Vida , Vértebras Lumbares , Envejecimiento
8.
World Neurosurg ; 179: 88-98, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37480984

RESUMEN

The general objectives of spine surgery are to alleviate pain, restore neurologic function, and prevent or treat spinal deformities or instability. The accumulating expanse of outcome measures has allowed us to more objectively quantify these variables and, therefore, gauge the success of treatments, ultimately improving the quality of the delivered health care. It has become increasingly evident that spinal conditions and their accompanying interventions affect all aspects of a patient's life, including their physical, mental, emotional, and social well-being. This underscores the challenge of creating clinically relevant and accurate outcome measures in spine care, and the reason why there is a growing recognition of the importance of subjective measures such as patient-reported outcome measures, that consider a patients' health-related quality of life. Subjective measures provide valuable insights into patient experiences and perceptions of treatment outcomes, whereas objective measures provide a reproducible glimpse into key radiographic and clinical parameters that are associated with a successful outcome. In this narrative review, we provide a detailed analysis of the most common subjective and objective outcome measures employed in spine surgery, with a special focus on their current role as well as the possible future of outcome reporting.


Asunto(s)
Calidad de Vida , Enfermedades de la Columna Vertebral , Humanos , Columna Vertebral/cirugía , Resultado del Tratamiento , Enfermedades de la Columna Vertebral/cirugía , Dolor , Medición de Resultados Informados por el Paciente
9.
World Neurosurg ; 175: 165-171, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37365762

RESUMEN

The craniovertebral junction (CVJ) involves the atlas, axis, and occiput along with the atlanto-occipital and atlantoaxial joints. The anatomy and neural and vascular anatomy of the junction render the CVJ unique. Specialists treating disorders that affect the CVJ must appreciate its intricate anatomy and should be well versed in its biomechanics. This first article in a three-article series provides an overview of the functional anatomy and biomechanics of the CVJ.


Asunto(s)
Articulación Atlantoaxoidea , Articulación Atlantooccipital , Humanos , Fenómenos Biomecánicos , Articulación Atlantooccipital/anatomía & histología , Articulación Atlantoaxoidea/anatomía & histología
10.
World Neurosurg ; 175: 183-189, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36990348

RESUMEN

In this third article in a 3-article series on the craniocervical junction, we define the terms "basilar impression," "cranial settling," "basilar invagination," and "platybasia," noting that these terms are often used interchangeably but represent distinct entities. We then provide examples that represent these pathologies and treatment paradigms. Finally, we discuss the challenges and future direction in the craniovertebral junction surgery space.


Asunto(s)
Platibasia , Humanos , Platibasia/cirugía , Cráneo/cirugía , Descompresión Quirúrgica
11.
World Neurosurg ; 175: 172-182, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36990349

RESUMEN

The craniovertebral junction (CVJ), or the "first junction," can be affected by a variety of pathological states. Some of these conditions could represent a gray area in that they can be treated by general neurosurgeons or such specialists as skull base or spinal surgeons. However, some conditions are best managed with a multidisciplinary approach. The importance of in-depth knowledge of the anatomy and biomechanics of this junction cannot be overemphasized. Identifying what represents clinical stability or instability is key to successful diagnosis and, hence, treatment. In this report, the second in a 3-article series, we describe our approach to managing CVJ pathologies in a case-based fashion to illustrate key concepts.


Asunto(s)
Base del Cráneo , Columna Vertebral , Humanos , Base del Cráneo/cirugía , Fenómenos Biomecánicos
12.
J Craniovertebr Junction Spine ; 14(3): 221-229, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37860027

RESUMEN

Objective: Venous thromboembolic event (VTE) after spine surgery is a rare but potentially devastating complication. With the advent of machine learning, an opportunity exists for more accurate prediction of such events to aid in prevention and treatment. Methods: Seven models were screened using 108 database variables and 62 preoperative variables. These models included deep neural network (DNN), DNN with synthetic minority oversampling technique (SMOTE), logistic regression, ridge regression, lasso regression, simple linear regression, and gradient boosting classifier. Relevant metrics were compared between each model. The top four models were selected based on area under the receiver operator curve; these models included DNN with SMOTE, linear regression, lasso regression, and ridge regression. Separate random sampling of each model was performed 1000 additional independent times using a randomly generated training/testing distribution. Variable weights and magnitudes were analyzed after sampling. Results: Using all patient-related variables, DNN using SMOTE was the top-performing model in predicting postoperative VTE after spinal surgery (area under the curve [AUC] =0.904), followed by lasso regression (AUC = 0.894), ridge regression (AUC = 0.873), and linear regression (AUC = 0.864). When analyzing a subset of only preoperative variables, the top-performing models were lasso regression (AUC = 0.865) and DNN with SMOTE (AUC = 0.864), both of which outperform any currently published models. Main model contributions relied heavily on variables associated with history of thromboembolic events, length of surgical/anesthetic time, and use of postoperative chemoprophylaxis. Conclusions: The current study provides promise toward machine learning methods geared toward predicting postoperative complications after spine surgery. Further study is needed in order to best quantify and model real-world risk for such events.

13.
Anesth Analg ; 115(2): 348-53, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22584548

RESUMEN

BACKGROUND: Lumbar discectomy surgery is a common neurosurgical procedure. Neuraxial labor analgesia may be less effective in parturients with a history of discectomy surgery because of postsurgical scarring and anatomical distortion. In this prospective observational case-controlled study, we compared bupivacaine consumption per hour of labor analgesia as an indirect measure of labor analgesic effectiveness between women with prior discectomy surgery and those who did not have back surgery. METHODS: All women with prior discectomy surgery who requested neuraxial labor analgesia at a high-volume, single university-affiliated women's hospital during the study period were approached. Control subjects were matched for anesthesiologist skill level. The primary outcome was bupivacaine consumption per hour of labor analgesia. Characteristics associated with the epidural catheter placement including the number of interspaces attempted, time to placement, and number of epidural catheters replaced for inadequate analgesia were recorded. Subject characteristics, labor outcomes, and analgesia outcomes were analyzed using the Wilcoxon ranked sum or Fisher exact test. Epidural placement data were analyzed using the Wilcoxon signed rank, McNemar's, or sign test. RESULTS: Data were analyzed for 42 women in the discectomy group and 42 women in the control group. Bupivacaine consumption per hour of labor analgesia was not different between groups (median [interquartile range, IQR]: discectomy 12.7 mg/h [11.0 to 15.3] and control 13.2 mg/h [11.3 to 15.7]; difference in medians [95% confidence interval, CI]: -0.55 mg/h [-1.33 to 1.39]; P = 0.43). The interval from initiation of neuraxial analgesia and delivery and mode of delivery did not differ between groups. The median difference (95% CI) in the time to place the epidural catheter between the discectomy and control subjects was 0 minute (-1 to 2.5); P = 0.38. More than 1 interspace was attempted in 17% discectomy in comparison with 2% of the control subjects-difference (95% CI) 15% (2-26); P = 0.03. The neuraxial technique and estimated level of catheter placement did not differ. Completion of the procedure by a more senior anesthesiologist occurred in 3 discectomy subjects and 2 control subjects (P = 1.0). No epidural catheters were replaced. CONCLUSIONS: There was no difference in hourly bupivacaine consumption in parturients with prior lumbar discectomy surgery undergoing neuraxial labor analgesia in comparison with controls. Time to placement of the epidural catheter was not different either, but more interspaces were attempted in the discectomy group. Our findings suggest that standard clinical neuraxial analgesic methods are effective in women with discectomy surgery.


Asunto(s)
Analgesia Obstétrica , Analgesia Controlada por el Paciente , Anestésicos Locales/administración & dosificación , Bupivacaína/administración & dosificación , Discectomía , Disco Intervertebral/cirugía , Dolor de Parto/tratamiento farmacológico , Vértebras Lumbares/cirugía , Adulto , Estudios de Casos y Controles , Chicago , Discectomía/efectos adversos , Femenino , Hospitales Universitarios , Humanos , Dolor de Parto/diagnóstico , Dimensión del Dolor , Embarazo , Estudios Prospectivos , Factores de Tiempo
14.
Clin Neurol Neurosurg ; 223: 107506, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-36347180

RESUMEN

OBJECTIVE: Anterior lumbar fusions are thought to be associated with elevated venous thromboembolic event (VTE) rates, but the magnitude of this increase in VTE is not well described. The objective of this study was to quantify any increase in VTE caused by anterior approach lumbar fusion. METHODS: 1147 consecutive lumbar fusions performed at our institution over a six-year period were identified, and clinical and demographic data were collected. K-nearest neighbor propensity score matching and propensity score adjusted regression were performed. Patients undergoing anterior versus posterior approach lumbar fusions were matched according to age, body mass index, sex, VTE history, estimated blood loss, length of surgery, transfusion, selection for postoperative intensive care unit (ICU) admission, comorbid disease burden, and use of chemoprophylactic anticoagulation. RESULTS: Anterior approach surgery (OR=4.29, p < 0.001), a history of VTE (OR=8.67, p < 0.001), age (OR=1.53, p = 0.014), length of surgery (OR=1.16, p = 0.044), and selection for postoperative ICU admission (OR=4.60, p = 0.005) were independently associated with VTE on multivariable regression. 1058 anterior or posterior approach fusion patients were matched. After matching, overall bias was reduced by 71.0 %, no covariates remained significantly different between groups, and propensity scores were well balanced between populations (Rubin's B≤0.25, 0.5 ≤Rubin's R≤2.0). Significantly more patients in the anterior group underwent lower extremity duplex ultrasonography (LED) (36.9 % vs. 14.8 %, OR=3.36 [2.38, 4.76], p < 0.0001), and a statistically insignificantly higher proportion of LEDs were positive among patients in the anterior group (23.2 % vs. 13.2 %, OR=1.99 [0.92, 4.25], p = 0.108). After matching, the rate of VTE was 8.6 % for the anterior group and 1.3 % for the posterior group, with anterior approach surgery causing an increase in VTE by 7.2 % (95 % CI [2.28 %, 12.16 %], p = 0.004). CONCLUSION: Among patients undergoing lumbar fusions, anterior approach surgery causes an increase in VTE by 7.2%, which is a multifold increase in the proportion of patients with thromboembolic complications.


Asunto(s)
Fusión Vertebral , Tromboembolia Venosa , Humanos , Tromboembolia Venosa/epidemiología , Tromboembolia Venosa/etiología , Complicaciones Posoperatorias/etiología , Causalidad , Vértebras Lumbares/cirugía , Estudios Retrospectivos , Fusión Vertebral/efectos adversos
15.
Clin Neurol Neurosurg ; 220: 107360, 2022 09.
Artículo en Inglés | MEDLINE | ID: mdl-35868202

RESUMEN

OBJECTIVE: Metastatic spinal tumors commonly arise from primary breast cancer. We assessed outcomes and identified associated variables for patients who underwent surgical management for spinal metastases of breast cancer. METHODS: We retrospectively reviewed patients surgically treated for spinal metastases of breast cancer. Neurologic and functional outcomes were analyzed via Frankel scale and Karnofksy Performance Status (KPS) scores, respectively. Variables associated with Frankel and KPS scores after surgery were identified. Multivariable analysis was used to assess predictors for postoperative survival. RESULTS: Forty-nine patients were identified. There was no significant difference in Frankel scores postoperatively and at last follow-up. KPS scores (P = 0.002) significantly improved at last follow-up. Preoperative non-ambulation and postprocedural complications were associated with non-ambulation postoperatively. Postprocedural complications and disease-free interval (DFI) < 24 and < 60 months were associated with functional impairment at last follow-up. Current smoking status at the time of surgery (P = 0.021) and triple negative (negative immunohistochemistry for estrogen receptor, progesterone receptor, and HER2) breast cancer (P = 0.038) were significantly associated with shortened postoperative survival. CONCLUSION: When indicated, surgery for spinal metastases of breast cancer leads to preservation of neurologic status and long-term functional improvement. Preoperative ambulatory status and postprocedural complications were associated with ambulatory status after surgery, while postprocedural complications and shortened DFI were associated with functional status after surgery.Current smoking status at the time of surgery and triple negative breast cancer are negative predictors for postoperative survival after metastatic breast cancer to the spine.


Asunto(s)
Neoplasias de la Mama , Neoplasias de la Columna Vertebral , Neoplasias de la Mama/patología , Femenino , Humanos , Periodo Posoperatorio , Estudios Retrospectivos , Neoplasias de la Columna Vertebral/secundario , Columna Vertebral/cirugía , Resultado del Tratamiento
16.
Neurosurg Focus ; 30(3): E12, 2011 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-21361750

RESUMEN

The surgical management of compressive cervical ossification of the posterior longitudinal ligament (OPLL) can be challenging. Traditionally, approach indications for decompression of cervical spondylotic myelopathy have been used. However, the postoperative complication profile after cervical OPLL decompression is unique and may require an alternative approach paradigm. The authors review the literature on approach-related OPLL complications and suggest a management strategy for patients with single- or multiple-segment OPLL with or without greater than 50% canal stenosis.


Asunto(s)
Vértebras Cervicales/cirugía , Descompresión Quirúrgica/efectos adversos , Osificación del Ligamento Longitudinal Posterior/cirugía , Complicaciones Posoperatorias , Vértebras Cervicales/patología , Humanos , Ligamentos Longitudinales/patología , Ligamentos Longitudinales/cirugía , Osificación del Ligamento Longitudinal Posterior/patología , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/patología , Resultado del Tratamiento
17.
Neurosurg Focus ; 30(3): E16, 2011 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-21361754

RESUMEN

The management of thoracic ossification of the posterior longitudinal ligament has been studied by many spinal surgeons. Indications for operative intervention include progressive radiculopathy, myelopathy, and neurological deterioration. The ideal surgery for decompression remains highly debatable as various methods of surgical treatment of ossification of the posterior longitudinal ligament have been devised. Although numerous modifications to the 3 main approaches have been identified (anterior, posterior, or lateral), the indication for each depends on the nature of compression, the morphology of the lesion, the level of the compression, the structural alignment of the spine, and the neurological status of the patient. The authors discuss treatment techniques for thoracic ossification of the posterior longitudinal ligament, cite case examples from a single institution, and review the literature.


Asunto(s)
Osificación del Ligamento Longitudinal Posterior/diagnóstico por imagen , Osificación del Ligamento Longitudinal Posterior/cirugía , Vértebras Torácicas/diagnóstico por imagen , Vértebras Torácicas/cirugía , Adulto , Manejo de la Enfermedad , Femenino , Humanos , Ligamentos Longitudinales/diagnóstico por imagen , Ligamentos Longitudinales/cirugía , Persona de Mediana Edad , Radiografía
18.
Neurosurg Focus ; 31(4): E16, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21961860

RESUMEN

Perioperative abdominal complications associated with spine surgery are rare. Although most known abdominal complications occur in conjunction with anterior spinal fusions, there is a paucity of reports reviewing abdominal complications occurring with posterior spinal fusions. The authors review 4 patients who experienced a perioperative abdominal complication following a posterior spinal fusion. In each of these patients, a history of abdominal surgery is present. Given the physiological changes that occur with surgery in the prone position, patients with previous abdominal surgeries are at risk for developing abdominal complications in the perioperative period.


Asunto(s)
Traumatismos Abdominales/diagnóstico por imagen , Traumatismos Abdominales/etiología , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/etiología , Fusión Vertebral/efectos adversos , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Radiografía
19.
Neurosurg Focus ; 31(4): E4, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21961867

RESUMEN

OBJECT: Recently, the minimally invasive, lateral retroperitoneal, transpsoas approach to the thoracolumbar spinal column has been described by various authors. This is known as the minimally invasive lateral lumbar interbody fusion. The purpose of this study is to elucidate the approach-related morbidity associated with the minimally invasive transpsoas approach to the lumbar spine. To date, there have been only a couple of reports regarding the morbidity of the transpsoas muscle approach. METHODS: A nonrandomized, prospective study utilizing a self-reported patient questionnaire was conducted between January 2006 and June 2008 at Northwestern University. Data were collected in 53 patients with a follow-up period ranging from 6 months to 3.5 years. Only 2 patients were lost to follow-up. RESULTS: Thirty-six percent (19 of 53) of patients reported subjective hip flexor weakness, 25% (13 of 53) anterior thigh numbness, and 23% (12 of 53) anterior thigh pain. However, 84% of the 19 patients reported complete resolution of their subjective hip flexor weakness by 6 months, and most experienced improved strength by 8 weeks. Of those reporting anterior thigh numbness and pain, 69% and 75% improved to their baseline function by the 6-month follow-up evaluations, respectively. All patients with self-reported subjective hip flexor weakness underwent examinations during subsequent clinic visits after surgery; however, these examinations did not confirm a motor deficit less than Grade 5. Subset analysis showed that the L3-4 and L4-5 levels were most often affected. CONCLUSIONS: The minimally invasive, transpsoas muscle approach to the lumbar spine has a number of advantages. The data show that a percentage of the patients undergoing the transpsoas approach will have temporary sensory and motor symptoms related to this approach. The majority of the symptoms are thought to be related to psoas muscle inflammation and/or stretch injury to the genitofemoral nerve due to the surgical corridor traversed during the operation. No major injuries to the lumbar plexus were encountered. It is important to educate patients prior to surgery of the possibility of these largely transient symptoms.


Asunto(s)
Vértebras Lumbares/cirugía , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Complicaciones Posoperatorias/epidemiología , Músculos Psoas/cirugía , Fusión Vertebral/métodos , Estudios de Seguimiento , Humanos , Vértebras Lumbares/patología , Procedimientos Quirúrgicos Mínimamente Invasivos/efectos adversos , Morbilidad , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/prevención & control , Estudios Prospectivos , Fusión Vertebral/efectos adversos
20.
Neurosurg Focus ; 30(3): E3, 2011 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-21434819

RESUMEN

OBJECT: Ossification of the posterior longitudinal ligament (OPLL) is a complex multifactorial disease process combining both metabolic and biomechanical factors. The role for surgical intervention and choice of anterior or posterior approach is controversial. The object of this study was to review the literature and present a single-institution experience with surgical intervention for OPLL. METHODS: The authors performed a retrospective review of their institutional experience with surgical intervention for cervical OPLL. They also reviewed the English-language literature regarding the epidemiology, pathophysiology, natural history, and surgical intervention for OPLL. RESULTS: Review of the literature suggests an improved benefit for anterior decompression and stabilization or posterior decompression and stabilization compared with posterior decompression via laminectomy or laminoplasty. Both anterior and posterior approaches are safe and effective means of decompression of cervical stenosis in the setting of OPLL. CONCLUSIONS: Anterior cervical decompression and reconstruction is a safe and appropriate treatment for cervical spondylitic myelopathy in the setting of OPLL. For patients with maintained cervical lordosis, posterior cervical decompression and stabilization is advocated. The use of laminectomy or laminoplasty is indicated in patients with preserved cervical lordosis and less than 60% of the spinal canal occupied by calcified ligament in a "hill-shaped" contour.


Asunto(s)
Vértebras Cervicales/cirugía , Descompresión Quirúrgica/métodos , Osificación del Ligamento Longitudinal Posterior/etiología , Osificación del Ligamento Longitudinal Posterior/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Vértebras Cervicales/diagnóstico por imagen , Manejo de la Enfermedad , Femenino , Humanos , Ligamentos Longitudinales/diagnóstico por imagen , Ligamentos Longitudinales/cirugía , Masculino , Persona de Mediana Edad , Radiografía , Estudios Retrospectivos
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