Childhood respiratory allergies and symptoms in highly polluted area of Central Europe.

The study investigated the associations between the prevalence of the childhood respiratory diseases and the long-term exposure to air pollution in the burdened area of Moravian-Silesian Region in the Czech Republic. The health data were collected during 2014 in 7,239 children 5, 9, 13 and 17 years of age. Exposure to PM10 and NO2 in the residence addresses was based on dispersion models and GIS based traffic-related indicators. PM10 levels were positively associated with both lifetime (OR 1.35; 95%CI 1.09-1.67) and current (OR 1.32; 95%CI 1.05-1.67) allergic rhinitis; current asthma was associated negatively. The associations between traffic indicator and respiratory health were not found. On the other hand, marked positive associations were found between the respiratory diseases and symptom severity structured into ordinal variables, and PM10 and NO2. Modelled long-term exposure to air pollution was associated with childhood allergic rhinitis and deterioration of the respiratory symptoms.

REFINING OF ASTHMA PREVALENCE SPATIAL DISTRIBUTION AND VISUALIZATION OF OUTDOOR ENVIRONMENT FACTORS USING GIS AND ITS APPLICATION FOR IDENTIFICATION OF MUTUAL ASSOCIATIONS.

AIM: This study presents a procedure of complex assessment of the environment impact on asthma prevalence. This approach is also applicable for any other disease which is supposed to be associated with the quality of the outdoor environment. METHODS: The input data included asthma prevalence values from the National Institute of Public Health (NIPH) cross-section questionnaire survey (13,456 children) and annual reports on activities of all paediatricians in the Czech Republic (2,072 surgeries); concentrations of PM10, PM2.5, NO2, SO2, O3, benzene, benzo(a)pyrene, As, Cd, Pb and Ni; emissions of total suspended particles, SO2, NOx, CO, VOC, NH3; traffic intensity; land cover (anthropogenic area, urban greenery, arable land, grassland, other agricultural land, forests); proportion of cultivation of individual agricultural crops (17 categories); and proportion of individual woods (15 categories). Using the Geographical Information Systems (GIS) analysis the integration of all source data through one spatial unit was achieved and complete data sets were compiled to be subjected to statistical analysis (combination of factor analysis with logistic/linear regression). RESULTS: In this study, the approach of combined use of GIS analyses and statistical evaluation of large input data sets was tested. The asthma prevalence demonstrated positive associations with the air pollution (PM10, PM2.5, benzene, benzo(a)pyren, SO2, Pb, Cd) and the rate of agricultural use of land (growing oats, rye, arable fodder crops). Conversely, there was a negative association with the occurrence of natural forests (ash, poplar, fir, beech, spruce, pine). No significant associations were observed with the distance from the road, traffic intensity and NO2 concentration. CONCLUSIONS: These findings suggest that the outdoor quality may be one of the crucial factors for asthma prevalence.

Levels of PCDDs, PCDFs, and PCBs in the blood of the non-occupationally exposed residents living in the vicinity of a chemical plant in the Czech Republic.

In 2003, concentrations of altogether 17 PCDD/Fs congeners and 12 non-ortho and mono-ortho dioxin-like PCBs were measured in the blood of 60 randomly selected adults who lived in three settlements surrounding a chemical plant that had been producing chlorinated herbicides (mainly HCHs, HCB, pentachlorophenole, 2,4,5-T) in the 1960's; subjects consuming home-produced animal foods were chosen. Twenty blood donors with similar characteristics from the locality with about 80 km distance were used as control subjects. The factors that influenced the dioxin levels were investigated on the basis of a questionnaire. The aim of our study was to find out whether the residents living in the surroundings of the chemical plant are at a greater exposure risk than the controls. To calculate TEQ values, WHO-TEFs were used. The concentrations of four PCDD and six PCDF congeners were below the LOD in more than 50% of samples. Significantly higher WHO-TEQ levels (p<0.05) were found for PCDDs, PCDFs, or PCBs in all three followed up groups compared with controls. The geometric means of the total TEQ values for PCDD/F/PCBs were 43.8, 50.2, and 40.0 pg/g fat compared to 23.2 pg/g fat in the control. The percentages of TEQ due to the measured congeners in exposed groups were 9-10.3% for PCDDs, 20.5-26.9% for PCDFs, 19.2-23.1% for coplanar and 43.6-47.2% for mono-ortho PCBs. In control, the percentage of TEQ was 11.6, 26.7, 24.1, and 37.5%. PCBs, predominantly PCB156, followed by PCB126 contributed 60 to 70% of the total TEQ value. Positive correlation of the PCDD/PCDF/PCB blood levels with age and with consumption of locally produced eggs was found.

Prevalence and risk factors of poor posture in school children in the Czech Republic.

BACKGROUND: The purpose of this study was to identify the prevalence and the main risk factors of poor posture in school children in the Czech Republic. METHODS: The cross-sectional study examined representative sample of children aged 7, 11, and 15 years in the year 2003. From the overall number of 3600 children, 3520 (97.7%) attended and were examined in preventive checkups. Data were obtained from medical examinations and from screening questionnaires. RESULTS: Poor posture was diagnosed in 38.3% children, more frequently in boys. A significantly different occurrence of poor posture was found between 7-year-old and 11-year-old children (33.0% and 40.8%, respectively). The most frequently detected defects were as follows: protruding scapulae (50% of all children), increased lumbar lordosis (32%), and round back (31%). Children with poor posture reported headache and pain in the cervical and lumbar spine more frequently. A total of 14% of children had body mass index levels over the 90th percentile, and the occurrence of poor posture was significantly less likely. On average, children spent 4 hours weekly performing sports activities and 14 hours weekly watching TV/VCR and playing computer games. No sports activities were reported by 20% of children, and these children had a significantly higher probability of poor posture than children performing sports. CONCLUSIONS: The results of our study can be used as an evidence with officials in the area of prevention, to support efforts to improve the health of our school children and to reduce the risk of postural damage to children's health.