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1.
Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC.
Pflugers Arch
; 473(1): 79-93, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33200256
2.
Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis.
Kidney Int
; 100(4): 850-869, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34252449
3.
Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione.
BMC Biol
; 18(1): 19, 2020 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32101139
4.
11ß-Hydroxysteroid dehydrogenases control access of 7ß,27-dihydroxycholesterol to retinoid-related orphan receptor γ.
J Lipid Res
; 60(9): 1535-1546, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31273032
5.
In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice.
Arch Toxicol
; 93(6): 1649-1664, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30993381
6.
IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.
Arch Toxicol
; 91(5): 2223-2234, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27734117
7.
Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells.
J Neuroinflammation
; 11: 190, 2014 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-25407356
8.
Acute effects of 3,4-methylenedioxymethamphetamine and methylphenidate on circulating steroid levels in healthy subjects.
Neuroendocrinology
; 100(1): 17-25, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24903002
9.
Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11ß-hydroxysteroid dehydrogenase 1 inhibitors.
Bioorg Med Chem Lett
; 23(19): 5397-400, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23981897
10.
Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells.
J Neuroinflammation
; 9: 260, 2012 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23190711
11.
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype.
J Endocrinol
; 253(3): 97-113, 2022 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35318963
12.
Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11ß-hydroxysteroid dehydrogenase 2 inhibitors.
Bioorg Med Chem
; 19(6): 1866-80, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21376605
13.
The ratio of ursodeoxycholyltaurine to 7-oxolithocholyltaurine serves as a biomarker of decreased 11ß-hydroxysteroid dehydrogenase 1 activity in mouse.
Br J Pharmacol
; 178(16): 3309-3326, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450045
14.
11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.
Bioorg Med Chem
; 18(4): 1507-15, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20100662
15.
Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples.
Metabolites
; 10(7)2020 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32660078
16.
Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes.
Sci Rep
; 10(1): 3035, 2020 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32080229
17.
Posaconazole-Induced Hypertension Due to Inhibition of 11ß-Hydroxylase and 11ß-Hydroxysteroid Dehydrogenase 2.
J Endocr Soc
; 3(7): 1361-1366, 2019 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31286100
18.
Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study.
J Steroid Biochem Mol Biol
; 186: 212-225, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30381248
19.
Enzymatic interconversion of the oxysterols 7ß,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11ß-hydroxysteroid dehydrogenase type 1 and 2.
J Steroid Biochem Mol Biol
; 190: 19-28, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30902677
20.
Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion.
Sci Rep
; 9(1): 19540, 2019 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31863073