Búsqueda | BVS CLAP/SMR-OPS/OMS

1.

A graph neural network approach for molecule carcinogenicity prediction.

Fradkin, Philip; Young, Adamo; Atanackovic, Lazar; Frey, Brendan; Lee, Leo J; Wang, Bo.

Bioinformatics ; 38(Suppl 1): i84-i91, 2022 06 24.

Artículo en Inglés | MEDLINE | ID: mdl-35758812

2.

Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes.

Blencowe, Benjamin J; Ahmad, Sidrah; Lee, Leo J.

Genes Dev ; 23(12): 1379-86, 2009 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-19528315

3.

Deep learning of the tissue-regulated splicing code.

Leung, Michael K K; Xiong, Hui Yuan; Lee, Leo J; Frey, Brendan J.

Bioinformatics ; 30(12): i121-9, 2014 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-24931975

4.

Genome-wide analysis of alternative splicing in Caenorhabditis elegans.

Ramani, Arun K; Calarco, John A; Pan, Qun; Mavandadi, Sepand; Wang, Ying; Nelson, Andrew C; Lee, Leo J; Morris, Quaid; Blencowe, Benjamin J; Zhen, Mei; Fraser, Andrew G.

Genome Res ; 21(2): 342-8, 2011 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-21177968

5.

Challenges in estimating percent inclusion of alternatively spliced junctions from RNA-seq data.

Kakaradov, Boyko; Xiong, Hui Yuan; Lee, Leo J; Jojic, Nebojsa; Frey, Brendan J.

BMC Bioinformatics ; 13 Suppl 6: S11, 2012 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-22537040

6.

IntroSpect: Motif-Guided Immunopeptidome Database Building Tool to Improve the Sensitivity of HLA I Binding Peptide Identification by Mass Spectrometry.

Zhang, Le; Liu, Geng; Hou, Guixue; Xiang, Haitao; Zhang, Xi; Huang, Ying; Zhang, Xiuqing; Li, Bo; Lee, Leo J.

Biomolecules ; 12(4)2022 04 14.

Artículo en Inglés | MEDLINE | ID: mdl-35454168

7.

The co-stimulation of anti-CD28 and IL-2 enhances the sensitivity of ELISPOT assays for detection of neoantigen-specific T cells in PBMC.

Tang, Yunxia; Zhu, Linnan; Xu, Qumiao; Zhang, Xiuqing; Li, Bo; Lee, Leo J.

J Immunol Methods ; 484-485: 112831, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32758496

8.

ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.

Guallar, Diana; Fuentes-Iglesias, Alejandro; Souto, Yara; Ameneiro, Cristina; Freire-Agulleiro, Oscar; Pardavila, Jose Angel; Escudero, Adriana; Garcia-Outeiral, Vera; Moreira, Tiago; Saenz, Carmen; Xiong, Heng; Liu, Dongbing; Xiao, Shidi; Hou, Yong; Wu, Kui; Torrecilla, Daniel; Hartner, Jochen C; Blanco, Miguel G; Lee, Leo J; López, Miguel; Walkley, Carl R; Wang, Jianlong; Fidalgo, Miguel.

Cell Stem Cell ; 27(2): 300-314.e11, 2020 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-32396862

9.

Characterization of RNA editome in primary and metastatic lung adenocarcinomas.

Peng, Lihua; Lee, Leo J; Xiong, Heng; Su, Hong; Rao, Junhua; Xiao, Dakai; He, Jianxing; Wu, Kui; Liu, Dongbing.

Oncotarget ; 8(7): 11517-11529, 2017 Feb 14.

Artículo en Inglés | MEDLINE | ID: mdl-28009993

10.

RED-ML: a novel, effective RNA editing detection method based on machine learning.

Xiong, Heng; Liu, Dongbing; Li, Qiye; Lei, Mengyue; Xu, Liqin; Wu, Liang; Wang, Zongji; Ren, Shancheng; Li, Wangsheng; Xia, Min; Lu, Lihua; Lu, Haorong; Hou, Yong; Zhu, Shida; Liu, Xin; Sun, Yinghao; Wang, Jian; Yang, Huanming; Wu, Kui; Xu, Xun; Lee, Leo J.

Gigascience ; 6(5): 1-8, 2017 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-28328004

11.

RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.

Xiong, Hui Y; Alipanahi, Babak; Lee, Leo J; Bretschneider, Hannes; Merico, Daniele; Yuen, Ryan K C; Hua, Yimin; Gueroussov, Serge; Najafabadi, Hamed S; Hughes, Timothy R; Morris, Quaid; Barash, Yoseph; Krainer, Adrian R; Jojic, Nebojsa; Scherer, Stephen W; Blencowe, Benjamin J; Frey, Brendan J.

Science ; 347(6218): 1254806, 2015 Jan 09.

Artículo en Inglés | MEDLINE | ID: mdl-25525159

12.

AVISPA: a web tool for the prediction and analysis of alternative splicing.

Barash, Yoseph; Vaquero-Garcia, Jorge; González-Vallinas, Juan; Xiong, Hui Yuan; Gao, Weijun; Lee, Leo J; Frey, Brendan J.

Genome Biol ; 14(10): R114, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24156756

13.

Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndrome.

McDonell, Laura M; Mirzaa, Ghayda M; Alcantara, Diana; Schwartzentruber, Jeremy; Carter, Melissa T; Lee, Leo J; Clericuzio, Carol L; Graham, John M; Morris-Rosendahl, Deborah J; Polster, Tilman; Acsadi, Gyula; Townshend, Sharron; Williams, Simon; Halbert, Anne; Isidor, Bertrand; David, Albert; Smyser, Christopher D; Paciorkowski, Alex R; Willing, Marcia; Woulfe, John; Das, Soma; Beaulieu, Chandree L; Marcadier, Janet; Geraghty, Michael T; Frey, Brendan J; Majewski, Jacek; Bulman, Dennis E; Dobyns, William B; O'Driscoll, Mark; Boycott, Kym M.

Nat Genet ; 45(5): 556-62, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23542699

14.

The evolutionary landscape of alternative splicing in vertebrate species.

Barbosa-Morais, Nuno L; Irimia, Manuel; Pan, Qun; Xiong, Hui Y; Gueroussov, Serge; Lee, Leo J; Slobodeniuc, Valentina; Kutter, Claudia; Watt, Stephen; Colak, Recep; Kim, TaeHyung; Misquitta-Ali, Christine M; Wilson, Michael D; Kim, Philip M; Odom, Duncan T; Frey, Brendan J; Blencowe, Benjamin J.

Science ; 338(6114): 1587-93, 2012 Dec 21.

Artículo en Inglés | MEDLINE | ID: mdl-23258890

15.

Transcriptional profiling of endocrine cerebro-osteodysplasia using microarray and next-generation sequencing.

Lahiry, Piya; Lee, Leo J; Frey, Brendan J; Rupar, C Anthony; Siu, Victoria M; Blencowe, Benjamin J; Hegele, Robert A.

PLoS One ; 6(9): e25400, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21980446

16.

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing.

Pan, Qun; Shai, Ofer; Lee, Leo J; Frey, Brendan J; Blencowe, Benjamin J.

Nat Genet ; 40(12): 1413-5, 2008 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-18978789

17.

How many new genes are there?

Lee, Leo J; Hughes, Timothy R; Frey, Brendan J.

Science ; 311(5768): 1709-11; author reply 1709-11, 2006 Mar 24.

Artículo en Inglés | MEDLINE | ID: mdl-16556823

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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