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1.
N-(3-Methoxyphenyl)-6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)pyridin-2-amine is an inhibitor of the FLT3-ITD and BCR-ABL pathways, and potently inhibits FLT3-ITD/D835Y and FLT3-ITD/F691L secondary mutants.
Bioorg Chem
; 143: 106966, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37995643
2.
Maternal and newborn metabolomic changes associated with urinary polycyclic aromatic hydrocarbon metabolite concentrations at delivery: an untargeted approach.
Metabolomics
; 20(1): 6, 2023 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38095785
3.
A Silent Threat: Exploring the Impact of Endocrine Disruption on Human Health.
Int J Mol Sci
; 24(12)2023 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37372939
4.
Differential methylation values in differential methylation analysis.
Bioinformatics
; 35(7): 1094-1097, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30184051
5.
NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries.
FASEB J
; 33(7): 8335-8348, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30991008
6.
oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA.
Bioinformatics
; 32(23): 3667-3669, 2016 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27522082
7.
Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors.
Nanomedicine
; 13(2): 403-410, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27520723
8.
Prostate Cancer Expression Profiles of Cytoplasmic ERß1 and Nuclear ERß2 are Associated with Poor Outcomes following Radical Prostatectomy.
J Urol
; 195(6): 1760-6, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26804755
9.
Effects of High-Butterfat Diet on Embryo Implantation in Female Rats Exposed to Bisphenol A.
Biol Reprod
; 93(6): 147, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26510865
10.
Estrogen receptor ß (ERß1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent manner.
J Biol Chem
; 288(35): 25038-25052, 2013 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23857583
11.
An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L.
Eur J Med Chem
; 264: 115977, 2024 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38056299
12.
The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/ß-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-ß catenin-p300 Interactions in Hepatocellular Carcinoma.
Adv Sci (Weinh)
; : e2308539, 2024 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38790135
13.
Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care.
Cancers (Basel)
; 15(23)2023 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38067237
14.
The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells.
Oncotarget
; 13: 46-60, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35018219
15.
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
J Med Chem
; 65(2): 1536-1551, 2022 01 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35081714
16.
Discovery of 4-aminoquinolines as highly selective TGFßR1 inhibitors with an attenuated MAP4K4 profile for potential applications in immuno-oncology.
Eur J Med Chem
; 225: 113763, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34419892
17.
Discovery and biological evaluation of phthalazines as novel non-kinase TGFß pathway inhibitors.
Eur J Med Chem
; 223: 113660, 2021 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34246853
18.
Discovery of imidazo[1,2-a]pyridine-thiophene derivatives as FLT3 and FLT3 mutants inhibitors for acute myeloid leukemia through structure-based optimization of an NEK2 inhibitor.
Eur J Med Chem
; 225: 113776, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34479037
19.
Three-Generation Study of Male Rats Gestationally Exposed to High Butterfat and Bisphenol A: Impaired Spermatogenesis, Penetrance with Reduced Severity.
Nutrients
; 13(10)2021 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-34684636
20.
Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer.
Prostate
; 70(7): 765-76, 2010 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20054818