1.
Org Biomol Chem
; 22(34): 6928-6932, 2024 Aug 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-39119751
RESUMEN
A facile synthetic method for direct C(sp2)-H bond trifluoromethylation of 3-methylene-isoindolin-1-ones under visible-light-induced metal-free conditions is presented. This protocol features mild reaction conditions, broad substrate scope and excellent functional group tolerance, resulting in a range of structurally diverse trifluoromethylated products in good to excellent yields.