Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
Más filtros

Banco de datos
Tipo del documento
Asunto de la revista
País de afiliación
Intervalo de año de publicación
1.
Am J Dermatopathol ; 37(4): 305-10, 2015 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24614207

RESUMEN

Cutaneous toxoplasmosis is a rare and diagnostically challenging entity. Today, the acquired form occurs predominantly in immunocompromised patients with human immunodeficiency virus or after hematopoietic stem cell transplantation. We report a case of cutaneous toxoplasmosis in a 6-year-old girl after allogeneic stem cell transplantation for immune-mediated encephalopathy, first manifesting at 16 months of age. In the post-transplant setting, she developed a rash consisting of approximately 8 scattered 3­4-mm round, erythematous macules and papules on her back, abdomen, and right shoulder. Sections from a biopsy of a lesion on the back revealed numerous spherules tightly packed within small cystic structures in the epidermis. The diagnosis of cutaneous toxoplasmosis was confirmed by an immunohistochemical stain for Toxoplasma gondii and polymerase chain reaction on the peripheral blood for the T. gondii genome. This case should raise awareness that acquired toxoplasmosis with cutaneous involvement can occur in the pediatric population, particularly in immunocompromised patients after stem cell transplantation. Early diagnosis and treatment of this life-threatening opportunistic infection may improve patient outcomes.


Asunto(s)
Trasplante de Células Madre Hematopoyéticas/efectos adversos , Huésped Inmunocomprometido , Inmunosupresores/efectos adversos , Infecciones Oportunistas/parasitología , Enfermedades Cutáneas Parasitarias/parasitología , Toxoplasma/aislamiento & purificación , Toxoplasmosis/parasitología , Antiprotozoarios/uso terapéutico , Biopsia , Niño , ADN Protozoario/genética , Quimioterapia Combinada , Resultado Fatal , Femenino , Humanos , Inmunohistoquímica , Infecciones Oportunistas/diagnóstico , Infecciones Oportunistas/inmunología , Reacción en Cadena de la Polimerasa , Enfermedades Cutáneas Parasitarias/diagnóstico , Enfermedades Cutáneas Parasitarias/inmunología , Factores de Tiempo , Toxoplasma/genética , Toxoplasma/inmunología , Toxoplasmosis/diagnóstico , Toxoplasmosis/inmunología , Resultado del Tratamiento
2.
J Drugs Dermatol ; 12(4): 403-9, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-23652887

RESUMEN

Keloids are the result of an overgrowth of dense fibrous tissue that usually develops after healing of a skin injury. Despite their common occurrence, keloids remain one of the most challenging dermatologic conditions to successfully treat. They are often symptomatic, do not usually regress spontaneously, and tend to recur after excision. Prevention of keloids is essential. A previous history of keloid development should be elicited. Wound closure with minimal tension and application of adjunctive therapies before abnormal healing is paramount. Education regarding wound care should be given in order to prevent infection and foreign body reactions. Elective surgery should be avoided in patients predisposed to developing keloids. In this article, we review recent advances in medical and surgical treatment of keloids.


Asunto(s)
Queloide/terapia , Educación del Paciente como Asunto/métodos , Piel/lesiones , Reacción a Cuerpo Extraño/complicaciones , Reacción a Cuerpo Extraño/prevención & control , Humanos , Queloide/etiología , Queloide/patología , Recurrencia , Piel/patología , Técnicas de Cierre de Heridas , Cicatrización de Heridas
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA