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1.
Pediatr Cardiol ; 41(5): 892-898, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32095851

RESUMEN

Accurate assessment of LV systolic function remains a challenge, especially in the pediatric population. Myocardial strain measurement by 2D speckle tracking echocardiography (2DSTE) is a relatively new modality for assessment of regional and global myocardial wall motion. This study aims to establish the normative value among various pediatric age groups at a large pediatric tertiary care institution and to describe the challenges encountered in establishing such strain data. Transthoracic echocardiograms were acquired in 121 healthy children (age 0-21 years) and were retrospectively analyzed. The global longitudinal strain (GLS) was obtained by 2D speckle tracking using Philips Epiq7® and QLAB post processing software. The normative value for left ventricular GLS (%) obtained in our study was - 20.8 ± 2.3 (< 1 year); - 21.4 ± 2.2 (1-4 years); - 19.6 ± 2.4 (5-9 years); - 19.4 ± 2.6 (10-14 years); - 18.9 ± 3.0 (15-21 years). There was a statistically significant difference in GLS between the different age groups. The BMI (kg/m2) of assessed subjects were 14.6 ± 2.3 (< 1 year); 16.3 ± 1.5 (1-4 years); 16.7 ± 2.3 (5-9 years); 21.3 ± 4.6 (10-14 years); 23.9 ± 5.9 (15-21 years). There was no significant difference in GLS by gender or by BMI found in our study. We present our experience with establishment of normative values of 2DSTE in our pediatric echocardiography lab. This study shows that age is the major determinant of variation in peak GLS in healthy subjects, emphasizing the importance of establishment of normative data among various age groups in pediatrics.


Asunto(s)
Ecocardiografía/métodos , Cardiopatías/fisiopatología , Ventrículos Cardíacos/diagnóstico por imagen , Función Ventricular Izquierda , Adolescente , Factores de Edad , Niño , Preescolar , Femenino , Voluntarios Sanos , Cardiopatías/epidemiología , Humanos , Lactante , Recién Nacido , Masculino , Contracción Miocárdica , Miocardio , Pediatría , Estudios Retrospectivos , Adulto Joven
2.
Echocardiography ; 36(3): 609-612, 2019 03.
Artículo en Inglés | MEDLINE | ID: mdl-30677173

RESUMEN

Myocarditis is a common cause for acute heart failure in the pediatric population. Various imaging modalities have evolved over the past 3 decades in order to noninvasively image the myocardium in this patient population. These include standard 2-dimensional echocardiographic imaging, tissue Doppler imaging, and magnetic resonance imaging of the heart. More recently, myocardial speckle tracking also known as strain imaging has been utilized to assess regional wall motion abnormalities with increasing accuracy. We report a case of acute myocarditis in a teenage female in whom progression of myocardial strain findings correlated with the rapidly evolving clinical course of the patient.


Asunto(s)
Corazón/diagnóstico por imagen , Corazón/fisiopatología , Miocarditis/complicaciones , Miocarditis/fisiopatología , Disfunción Ventricular Izquierda/etiología , Disfunción Ventricular Izquierda/fisiopatología , Enfermedad Aguda , Adolescente , Bloqueo Atrioventricular/etiología , Bloqueo Atrioventricular/fisiopatología , Bloqueo Atrioventricular/terapia , Cardiotónicos/uso terapéutico , Progresión de la Enfermedad , Ecocardiografía , Epinefrina/uso terapéutico , Femenino , Humanos , Inmunoglobulinas/uso terapéutico , Imagen por Resonancia Magnética , Milrinona/uso terapéutico , Miocarditis/terapia , Marcapaso Artificial , Disfunción Ventricular Izquierda/terapia
3.
BMJ Case Rep ; 13(9)2020 Sep 08.
Artículo en Inglés | MEDLINE | ID: mdl-32907870

RESUMEN

This case aims to remind all providers to scrutinise for atypical presentations of multisystem inflammatory syndrome in children (MIS-C) which may mimic a more routine diagnosis. In the absence of mucocutaneous symptoms, the diagnosis of MIS-C can be missed. Given the potential for rapid deterioration of patients with MIS-C, early treatment and inpatient interventions are necessary.


Asunto(s)
Dolor Abdominal/inmunología , COVID-19/diagnóstico , Fiebre/inmunología , SARS-CoV-2/aislamiento & purificación , Síndrome de Respuesta Inflamatoria Sistémica/diagnóstico , Taquicardia/inmunología , Dolor Abdominal/sangre , Dolor Abdominal/terapia , Dolor Abdominal/virología , Adenosina Monofosfato/análogos & derivados , Adenosina Monofosfato/uso terapéutico , Alanina/análogos & derivados , Alanina/uso terapéutico , Proteína C-Reactiva/análisis , COVID-19/sangre , COVID-19/inmunología , COVID-19/terapia , Prueba de Ácido Nucleico para COVID-19 , Prueba Serológica para COVID-19 , Niño , Diagnóstico Diferencial , Fiebre/sangre , Fiebre/terapia , Fiebre/virología , Humanos , Proteína Antagonista del Receptor de Interleucina 1/uso terapéutico , Intubación Intratraqueal , Masculino , Síndrome Mucocutáneo Linfonodular/diagnóstico , Miocarditis/diagnóstico , Nasofaringe/virología , Péptido Natriurético Encefálico/sangre , SARS-CoV-2/inmunología , Síndrome de Respuesta Inflamatoria Sistémica/sangre , Síndrome de Respuesta Inflamatoria Sistémica/inmunología , Síndrome de Respuesta Inflamatoria Sistémica/terapia , Taquicardia/sangre , Taquicardia/terapia , Taquicardia/virología , Resultado del Tratamiento , Tratamiento Farmacológico de COVID-19
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